• Title/Summary/Keyword: predictor importance

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Human Lung Insults due Air Pollutant -A Review for Priority Setting in the Research- (대기오염에 의한 폐장조직 손상 -연구방향의 설정을 위한 논의-)

  • 김건열;백도명
    • Journal of environmental and Sanitary engineering
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    • v.7 no.2
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    • pp.95-110
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    • 1992
  • Much progress has been made in understanding the subcellular events of the human lung injuries after acute exposure to environmental air pollutants. Host of those events represent oxidative damages mediated by reactive oxygen species such as superoxide, hydrogen peroxide, and the hydroxy, free radical. Recently, nitric oxide (NO) was found to be endogenously produced by endothelial cells and cells of the reticulo-endothelial system as endothelialderived relaxation factor (EDRF) which is a vasoactive and neurotransmitter substance. Together with superoxide, NO can form another strong oxidant, peroxonitrite. The relative importance of exogenous sources of $N0/N0_2$ and endogenous production of NO by the EDRF producing enzymes in the oxidative stresses to the heman lung has to be elucidated. The exact events leading to chronic irreversible damage are still yet to be known. From chronic exposure to oxidant gases, progressive epithelial and interstitial damages develop. Type I epithelial cells become thicker and cover a smaller average alveolar surface area while thee II cells proliferate instead. Under acute damages, the extent of loss of the alveolar epithelial cell lining, especially type II cells appears to be a good predictor of the ensuing irreversible damage to alveolar compartment. Interstitial matrix undergo remodeling during chronic exposure with increased collagen fibers and interstitial fibroblasts. However, Inany of these changes can be reversed after cessation of exposure. Among chronic lung injuries, genetic damages and repair responses received particular attention in view of the known increased lung cancer risks from exposure to several air pollutants. Heavy metals from foundry emission, automobile traffics, and total suspended particulate, especially polycystic aromatic hydrocarbons have been positively linked with the development of lung cancer. Asbestos in another air pollutant with known risk of lung cancer and mesothelioma, but asbestos fibers are nonauthentic in most bioassays. Studies using the electron spin resonance spin trapping method show that the presence of iron in asbestos accelerates the production of the hydroxy, radical in vitro. Interactions of these reactive oxygen species with particular cellular components and disruption of cell defense mechanisms still await further studies to elucidate the carcinogenic potential of asbestos fibers of different size and chemical composition. The distribution of inhaled pollutants and the magnitude of their eventual effects on the respiratory tract are determined by pollutant-independent physical factors such as anatomy of the respiratory tract and level and pattern of breathing, as well as by pollutant-specific phyco-chemical factors such as the reactivity, solubility, and diffusivity of the foreign gas in mucus, blood and tissue. Many of these individual factors determining dose can be quantified in vitro. However, mathematical models based on these factors should be validated for its integrity by using data from intact human lungs.

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A Study on Health-Promoting Lifestyles and Their Affecting Factors in Elementary School Nurses (초등학교 양호교사의 건강증진 생활양식 실천정도와 영향 요인에 관한 연구)

  • Park, So Young
    • Journal of the Korean Society of School Health
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    • v.10 no.1
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    • pp.51-63
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    • 1997
  • Changes in disease patterns increase the importance of health-promoting lifestyles in a healthy society. Thus health education in elementary schools is very important because the knowledge of health and health habits in this period become a habitual part of life. The purpose of this study is to identify the performance in promoting healthy lifestyles of elementary school nurses. Such data helps to provide data to judge whether they are capable health educators or not. The subjects were 365 elementary school nurses selected by purposive sample. The data were collected by a self reporting questionnaire from August to October of 1996. The methods used in this study were the health-promoting lifestyle profile developed by Park In Sook (1995) and Licker's flour-point scale. A Cronbach's ${\alpha}$, percentage, mean, standard deviation, ANOVA, Pearson's correlation coffcient and stepwise multiple regression in the SAS package were used to analyze the data. The results of this study were as follows: 1. 37.7% of the sample were aged between 30 and 39 and 33.7% were between 40 and 49. 44.9% of the sample had attended college. 87.7% of the sample were married. 42.5% of the sample were people with a career of 11~20 years, and 26.0% of it had 21 years or more of working experience as an elementary school nurses. 2. The average scores of the family function and the social support were 2.97 and 2.98 respectively. 3. 86.5% of the sample were satisfied with their job. 4. 85.8% of the sample answered that they were healthy and 14.2% answered that they were unhealthy. The average scores of the internal health locus of control and self-esteem were 3.35 and 3.15 respectively. 5. The average score of performance in health-promoting lifestyle variables was 3.16; the average scores for harmonious relationships, regular diet professional health maintenance, sanitary life, self-control, emotional support, diet, rest and sleep, exercise and activity. self-achievement, and diet control were 3.47, 3.30, 2.52. 3.60, 2.92, 3.18, 3.14, 3.11, 2.96, 3.26 and 3.12. The variable with the highest degree of correlation was a sanitary life, whereas the one with the lowest degree was professional health maintenance. 6. A significant difference was found in self-esteem according to age. There was a significant difference in the average score of internal health locus of control according to age and career. 7. There were significant differences in the health-promoting lifestyle performance depending on age, career and monthly household income. The longer the career, the higher the health-promoting lifestyle performance. 8. A weak positive correlation was found between self-esteem and health-promoting lifestyles performance(r=0.417, p<0.001) Also, a weak positive correlation was found between the internal health locus of control and health-promoting lifestyles performance (r=0.386, p<0.001). 9. Heath-promoting lifestyle performance showed significant correlations with family function, social support and job satisfaction. 10. Stepwise multiple regression analysis revealed that the most powerful predictor was the variance of family function. Social support, age, self-esteem, internal health locus of control, perceived heath status and job satisfaction accounted for 55.9% of the variance in heath-promoting lifestyle performance.

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Development of U-Service Priority Model Based on Customer and Provider's View (수요·공급자를 통합한 u-서비스 우선순위 평가모형 개발)

  • Jang, Jae-Ho;Um, Jung-Sup
    • Journal of the Korean Association of Geographic Information Studies
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    • v.11 no.2
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    • pp.132-147
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    • 2008
  • So far ubiquitous service (u-service) priority has seldom been empirically examined based on the customer's view. It is usual to prioritize the relative importance of u-service variables by the supplier's intuition and a few specialist's experienced knowledge. Such approaches have the disadvantage that they provide only limited empirical information on the field practices in relation to u-service since customer demand of u-service is poorly defined despite abundant interest in this problem. Therefore, the aim of this research was to develop u-service priority model in the context of multi-criteria framework integrating customer and supplier's view, using high technology acceptance theory as major controlling factors. An important question was how to measure or represent criteria that is important to u-service and should be included in a priority model. The selection criteria for the model variables were derived from high technology acceptance theory and AHP approach through the analysis of frequency count, elimination of overlapping factors and brainstorming with specialists. Daegu showed top-rankings in transportation-aid service, guidance service for the eyesight disabled and u-telematics service. In contrast, disaster prevention service and industrial specialized town service ranked highly in the typical supplier's approach were not a dominant determining factor in the u-service priority. The model identified the fact that typical high priority service in terms of supplier's view did not necessarily accompany the important predictor for the u-service priority.

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Importance of pulmonary valve morphology for pulmonary valve preservation in tetralogy of Fallot surgery: comparison of the echocardiographic parameters

  • Choi, Su Jin;Kwon, Jung Eun;Roh, Da Eun;Hyun, Myung Chul;Jung, Han Na;Lee, Young Ok;Cho, Joon Yong;Kim, Yeo Hyang
    • Clinical and Experimental Pediatrics
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    • v.63 no.5
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    • pp.189-194
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    • 2020
  • Background: The decision to use transannular patching (TAP) during tetralogy of Fallot (TOF) repair depends on the pulmonary valve annulus size; the z score of the pulmonary annulus is the most commonly used predictor. However, definitive results are not obtained with z scores as different z score data sets are used for different parameters. Purpose: This study aimed to identify the echocardiographic and other key factors that warranted a change in the surgical method during TOF surgery. Methods: Sixty-two patients were enrolled and divided into a pulmonary valve (PV) preservation group and a TAP group. Their medical records were reviewed. Results: The z score for PV annulus (PVA), ratio of the PVA to aortic annulus size, and ratio of PVA to descending aorta (DAO) size were significantly different between the PV preservation and TAP groups (-1.72±1.52 vs. -3.07±1.94, P=0.004; 0.62±0.12 vs. 0.50±0.14, P=0.002; and 1.32±0.32 vs. 1.07±0.36, P=0.008, respectively). For TAP repair, the PVA z score had a sensitivity of 65.4% and specificity of 73.1%, ratio of PVA to aortic annulus size had a sensitivity of 73.1% and specificity of 65.4%, and ratio of PVA to DAO size had a sensitivity of 69.2% and specificity of 57.7%. The TAP group showed more monocuspid PVs (P=0.011), while the PV preservation group showed more tricuspid PVs (P=0.027). Commissurotomy was more frequently performed in the PV preservation group than in the TAP group (P=0.001). Of patients with commissurotomy, 58% showed a PV z score<-2. Conclusion: Although various echocardiographic parameters may serve as predictors for determining surgical methods for TOF patients, the PV morphology and tissue characteristics should also be considered.

A Study on the Effects of the Cooperative Philosophy between SMEs to the Cooperative Activities and Performance (중소기업 간 협력철학이 협력활동과 협력성과에 미치는 영향에 관한 연구)

  • Lee, Jae-Sun
    • Journal of the Korea Convergence Society
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    • v.8 no.9
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    • pp.301-309
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    • 2017
  • This study analyzed the effect of cooperation activities among SMEs. In order to study empirical analysis, we classified the types of cooperation into four dimensions: technology cooperation, human resource cooperation, sales cooperation and financial cooperation. Review the role of the collaborative philosophy as a predictor. This study also analyzed the relationship between cooperation philosophy, cooperation activities and performance. The results of this study are as follows: First, the result of path analysis between cooperation philosophy and cooperation activities shows that cooperation philosophy has an important influence on technical cooperation, human resource cooperation, sales cooperation and financial cooperation. Second, the results of the relationship between cooperation activities and achievements, technical cooperation, human resource cooperation, and sales cooperation have an important influence on cooperation performance. The meaning of this study is as follows. Analyze empirical tests using the PSBP model from a partnership perspective. We are trying to verify the relationship with SMEs. Therefore, we can suggest a beneficial implication to explain the importance of cooperation activities between SMEs. Also, SME business units have a problem with technical information leakage when they form partnerships, but in order to overcome this problem, we can use cooperative philosophies and avoid negative views.

The Effect of Perceived Value, Satisfaction and Self-Congruity on the Revisit Intention and the Word-of-Mouth Intention (스키장 방문자들의 가치, 만족, 자아일치성이 재방문의도와 구전의도에 미치는 영향)

  • Hong, Sung-Kwon;Kim, Jae-Hyun;Jang, Ho-Chan
    • Journal of the Korean Institute of Landscape Architecture
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    • v.40 no.2
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    • pp.74-85
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    • 2012
  • As competition increases, ski resort managers need to search for ways to attract previous visitors or to gain new visitors through word-of-mouth. This study examined the impact of skiers' perceived value, satisfaction and self-congruity on the revisit intention and the positive word-af-mouth intention. Total respondents were also segmented into a promotion-focus and prevention-focus individuals then later examined the differences in the effect of independent variables between groups in order to suggest a managerial direction that will enhance business competency of ski resorts. Results from regression analysis showed that all independent variables utilized in this study were good predictors of two dependent variables. Specially, satisfaction was a highly significant predictor. Promotion and prevention-focused individuals were also differed in evaluating the importance of independent variables for their revisit and word-of-mouth intention. It means that self-regulatory focus is an effective variable for segmentation. More specifically, satisfaction was the only variable influencing the revisit intention for promotion-focused individuals; whereas both satisfaction and self-congruity had significant effects on the revisit intention for prevention-focused individuals. All independent variables had significant effects on the word-of-mouth intention, except self-congruity for promotion-focused individuals. This research suggests several managerial implications on the findings based on the analysis and the characteristics of the visitors.

Classification Tree Analysis to Assess Contributing Factors Influencing Biosecurity Level on Farrow-to-Finish Pig Farms in Korea (분류 트리 기법을 이용한 국내 일괄사육 양돈장의 차단방역 수준에 영향을 미치는 기여 요인 평가)

  • Kim, Kyu-Wook;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.33 no.2
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    • pp.107-112
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    • 2016
  • The objective of this study was to determine potential contributing factors associated with biosecurity level of farrow-to-finish pig farms and to develop a classification tree model to explore how these factors related to each other based on prediction model. To this end, the author analyzed data (n = 193) extracted from a cross-sectional study of 344 farrow-to-finish farms which was conducted between March and September 2014 aimed to explore swine disease status at farm level. Standardized questionnaires with information about basic demographical data and management practices were collected in each farm by on-site visit of trained veterinarians. For the classification of the data sets regarding biosecurity level as a dependent variable and predictor variables, Chi-squared Automatic Interaction Detection (CHAID) algorithm was applied for modeling classification tree. The statistics of misclassification risk was used to evaluate the fitness of the model in terms of prediction results. Categorical multivariate input data (40 variables) was used to construct a classification tree, and the target variable was biosecurity level dichotomized into low versus high. In general, the level of biosecurity was lower in the majority of farms studied, mainly due to the limited implementation of on-farm basic biosecurity measures aimed at controlling the potential introduction and transmission of swine diseases. The CHAID model illustrated the relative importance of significant predictors in explaining the level of biosecurity; maintenance of medical records of treatment and vaccination, use of dedicated clothing to enter the farm, installing fence surrounding the farm perimeter, and periodic monitoring of the herd using written biosecurity plan in place. The misclassification risk estimate of the prediction model was 0.145 with the standard error of 0.025, indicating that 85.5% of the cases could be classified correctly by using the decision rule based on the current tree. Although CHAID approach could provide detailed information and insight about interactions among factors associated with biosecurity level, further evaluation of potential bias intervened in the course of data collection should be included in future studies. In addition, there is still need to validate findings through the external dataset with larger sample size to improve the external validity of the current model.

The Effect of Collectivism on Anxiety Perception and Mental Health in Youth Unemployment (집합주의 문화가 청년실업에 대한 불안 지각 및 정신건강에 미치는 영향)

  • Minjung Cha;So Young Park;Hyun-joo Song;Younhee Roh
    • Korean Journal of Culture and Social Issue
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    • v.18 no.1
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    • pp.27-51
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    • 2012
  • The current paper examines the effect of collectivism on perceived youth unemployment anxiety as well as mental health and the mediating effects of employment self-efficacy; self-esteem; and the frequency of upward and downward social comparisons. In Study 1, data were gathered from 179 university students in upper-ranking schools and middle-ranking schools in Seoul, Korea. Our results indicated that (a) collectivism was positively correlated to, and also an significant predictor of perceived youth unemployment anxiety and mental health and (b) employment self-efficacy and self-esteem had mediating effects on the relationship between collectivism and perceived youth unemployment anxiety and mental health. In Study 2, data were gathered from 118 students in upper-ranking schools in Seoul, Korea. Our results indicated that (c) upward social comparison had mediating effects on the relationship between collectivism and perceived youth unemployment anxiety and mental health, while downward social comparison did not. The findings are discussed in terms of their general implications for understanding the importance of culture in employment seeking settings.

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Role and Clinical Importance of Progressive Changes in Echocardiographic Parameters in Predicting Outcomes in Patients With Hypertrophic Cardiomyopathy

  • Kyehwan Kim;Seung Do Lee;Hyo Jin Lee;Hangyul Kim;Hye Ree Kim;Yun Ho Cho;Jeong Yoon Jang;Min Gyu Kang;Jin-Sin Koh;Seok-Jae Hwang;Jin-Yong Hwang;Jeong Rang Park
    • Journal of Cardiovascular Imaging
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    • v.31 no.2
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    • pp.85-95
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    • 2023
  • BACKGROUND: The prognostic utility of follow-up transthoracic echocardiography (FU-TTE) in patients with hypertrophic cardiomyopathy (HCM) is unclear, specifically in terms of whether changes in echocardiographic parameters in routine FU-TTE parameters are associated with cardiovascular outcomes. METHODS: From 2010 to 2017, 162 patients with HCM were retrospectively enrolled in this study. Using echocardiography, HCM was diagnosed based on morphological criteria. Patients with other diseases that cause cardiac hypertrophy were excluded. TTE parameters at baseline and FU were analyzed. FU-TTE was designated as the last recorded value in patients who did not develop any cardiovascular event or the latest exam before event development. Clinical outcomes were acute heart failure, cardiac death, arrhythmia, ischemic stroke, and cardiogenic syncope. RESULTS: Median interval between the baseline TTE and FU-TTE was 3.3 years. Median clinical FU duration was 4.7 years. Septal trans-mitral velocity/mitral annular tissue Doppler velocity (E/e'), tricuspid regurgitation velocity, left ventricular ejection fraction (LVEF), and left atrial volume index (LAVI) at baseline were recorded. LVEF, LAVI, and E/e' values were associated with poor outcomes. However, no delta values predicted HCM-related cardiovascular outcomes. Logistic regression models incorporating changes in TTE parameters had no significant findings. Baseline LAVI was the best predictor of a poor prognosis. In survival analysis, an already enlarged or increased size LAVI was associated with poorer clinical outcomes. CONCLUSIONS: Changes in echocardiographic parameters extracted from TTE did not assist in predicting clinical outcomes. Cross-sectionally evaluated TTE parameters were superior to changes in TTE parameters between baseline and FU at predicting cardiovascular events.

Atherogenic index of plasma and its association with food group intake in Korean adults: based on the baseline data of KoGES-HEXA study (우리나라 성인에서 atherogenic index of plasma와 식품군 섭취의 관련성: 도시기반 코호트 자료를 활용하여)

  • Hye Ran Shin;SuJin Song
    • Journal of Nutrition and Health
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    • v.57 no.1
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    • pp.105-119
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    • 2024
  • Purpose: The atherogenic index of plasma (AIP) is gaining recognition as a superior predictor of coronary artery disease. This study examined the relationship between the AIP and the intake of various food groups in Korean adults, using the baseline data from the Korean Genome and Epidemiology Study-The Health Examinees (KoGES-HEXA) study. Methods: This study included 133,381 adults (46,288 men, 87,093 women) who completed the nutrition survey and biochemical tests of the KoGES-HEXA study. The AIP was calculated as the log (triglycerides/high-density lipoprotein-cholesterol) and was divided into quintiles according to sex for further analysis. Data on food group intake were obtained using the semi-quantitative food frequency questionnaire, and daily food group intake (g/d) was evaluated for each individual. The association between the food group intake and the AIP was examined using the linear regression analysis after adjusting for the confounding variables. Results: In this study population, there was a positive correlation between energy intake and the AIP in men whereas an inverse assocation was shown in women (p < 0.001). In women, a rise in the AIP significantly correlated with an increased percentage of energy intake derived from carbohydrates but decreased percentages of energy from protein and fat (p < 0.001). In men and women, the consumption of grains and kimchi/pickles increased as the AIP rose, while the intake of legumes, nuts, meat and its products, eggs, fish, and milk and dairy products decreased. Among men, individuals in the highest AIP group showed higher intake of wheat products than those in the lowest group of the AIP. In women, the AIP was inversely correlated with potatoes and beverages consumption. Conclusion: This study highlights the importance of a balanced diet, including various protein sources, milk and dairy products, legumes, and nuts, for preventing cardiovascular diseases. Further research into sex-specific dietary patterns is essential for tailoring appropriate dietary recommendations.