• Title/Summary/Keyword: pre-transition

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Allyloxy-and Benzyloxy-Substituted Pyridine-bis-imine Iron(II) and Cobalt(II) Complexes for Ethylene Polymerization

  • Kim Il;Han Byeong Heui;Kim Jae Sung;Ha Chang-Sik
    • Macromolecular Research
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    • v.13 no.1
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    • pp.2-7
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    • 2005
  • A series of ethylene polymerization catalysts based on tridentate bis-imine ligands coordinated to iron and cobalt was reported. The ligands were prepared through the condensation of sterically bulky anilines with allyloxy-and benzyloxy-substituted 2,6-acetylpyridines. The pre-catalyst complexes were penta-coordinate species of the general formula $\{[(ArN=C(Me))_2(4-RO-C_5H_3N)]MCl_2\}$ (Ar=ortho dialkyl-substituted aryl ring; R=allyl, benzyl; M=Fe, Co). In the presence of ethylene and methyl alumoxane cocatalysts, these complexes were active for the polymerization of ethylene, with activities lower than those of metal complexes of the general formula $\{[(2-ArN=C(Me)_2C_5H_3N]MCl_2\}$ (Ar=ortho dialkyl-substituted aryl ring; M=Co, Fe), containing no substituents in 2,6-acetylpyridine ring. The effects of the catalyst structure and temperature on the polymerization activity, thermal properties, and molecular weight were discussed.

Application Effects of STS Module Concerning Food Waste (음식물 쓰레기에 관한 STS 모듈의 적용 효과)

  • Lee, Nae-Hwan;Cha, Hee-Young;Kim, Sung-Ha
    • Hwankyungkyoyuk
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    • v.18 no.1 s.26
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    • pp.44-54
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    • 2005
  • This study is intended to examine an effectiveness of STS module concerning food waste, 'Even if food waste is the money, would you throw it away', in the areas of affective domains related to science and attitudes towards environmental problems. For this study, one group of 142 seventh graders attending 'L' middle school in Iksan city, Jeonrabukdo received 8 class hours with this module. Their affective domains related to science and attitudes towards environmental problems were measured by pre- and post-test design in a single group. In addition, their views on STS instruction was also analyzed. Results are as follows. Students in the transition period who had been taught with this module showed that they had a statistically significant effectiveness in interests related to science, scientific attitudes and execution towards environmental problems(p<.05). Students taught with this module had a positive views on the STS instructional methods or contents. It was also shown that their recognition or behavior towards environmental problems have been changed positively.

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Daily Rainfall Simulation by Rainfall Frequency and State Model of Markov Chain (강우 빈도와 마코프 연쇄의 상태모형에 의한 일 강우량 모의)

  • Jung, Young-Hun;Kim, Buyng-Sik;Kim, Hung Soo;Shim, Myung-Pil
    • Journal of Wetlands Research
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    • v.5 no.2
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    • pp.1-13
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    • 2003
  • In Korea, most of the rainfalls have been concentrated in the flood season and the flood study has received more attention than low flow analysis. One of the reasons that the analysis of low flows has less attention is the lacks of the required data like daily rainfall and so we have used the stochastic processes such as pulse noise, exponential distribution, and state model of Markov chain for the rainfall simulation in short term such as daily. Especially this study will pay attention to the state model of Markov chain. The previous study had performed the simulation study by the state model without considerations of the flood and non-flood periods and without consideration of the frequency of rainfall for the period of a state. Therefore this study considers afore mentioned two cases and compares the results with the known state model. As the results, the RMSEs of the suggested and known models represent the similar results. However, the PRE(relative percentage error) shows the suggested model is better results.

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Hed1 Promotes Meiotic Crossover Formation in Saccharomyces cerevisiae

  • Kong, Yoon-Ju;Joo, Jeong-Hwan;Kim, Keun Pil;Hong, Soogil
    • Journal of Microbiology and Biotechnology
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    • v.27 no.2
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    • pp.405-411
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    • 2017
  • Homologous recombination occurs between homologous chromosomes and is significantly involved in programmed double-strand break (DSB) repair. Activation of two recombinases, Rad51 and Dmc1, is essential for an interhomolog bias during meiosis. Rad51 participates in both mitotic and meiotic recombination, and its strand exchange activity is regulated by an inhibitory factor during meiosis. Thus, activities of Rad51 and Dmc1 are coordinated to promote homolog bias. It has been reported that Hed1, a meiosis-specific protein in budding yeast, regulates Rad51-dependent recombination activity. Here, we investigated the role of Hed1 in meiotic recombination by ectopic expression of the protein after pre-meiotic replication in Saccharomyces cerevisiae. DNA physical analysis revealed that the overexpression of Hed1 delays the DSB-to-joint molecule (JM) transition and promotes interhomolog JM formation. The study indicates a possible role of Hed1 in controlling the strand exchange activity of Rad51 and, eventually, meiotic crossover formation.

Bayes Rule for MAC State Sojourn Time Supporting Packet Data Service in CDMA Wireless Celluar Networks

  • Park, Cheon-Won;Kim, Dong-Joon;Shin, Woo-Cheol;Ju, Jee-Hwan
    • Proceedings of the IEEK Conference
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    • 2002.07c
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    • pp.1606-1609
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    • 2002
  • MAC state models appeared with an effort to overcome technical demerits of CDMA in provisioning packet data service. In the scenario of sojourn and transition on MAC states, the design of state sojourn time is a critical issue for an efficient utilization of limited recource; a longer sojourn time leads to more resource being preserved for inactive stations, while more connection components should be recovered with a shorter sojourn time. Thus, the sojourn time at each MAC state must be optimized in consideration of these two conflicting arguments. In this paper, we first present a generic MAC state model. Secondly, based on the generic model, we reveal a relation of inactive period and the delay time of the last packet served in pre- ceding active period and specify a loss function reflect-ing two antinomic features that result from a change of state sojourn time. Using the proposed loss function, we construct a decision problem to find an optima3 rule for state sojourn times. Finally, we present a way of computing Bayes rule by use of the posterior distribution of inactivity duration for given observation on the delay time of last packet. Furthermore, Bayes rules are explicitly expressed for special arrival processes and investigated with respect to traffic load and loss parameters.

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A Study on the Conceptual Origin of Pathogenic Qi in the Mawangdui Yishu (마왕퇴의서 속 사기(邪氣)의 시원적(始原的) 개념 고찰)

  • Lee, Kyung
    • Journal of Korean Medical classics
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    • v.35 no.1
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    • pp.81-92
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    • 2022
  • Objectives : This paper aims to analyze the origins of the pathogenic qi[邪氣] concept through analysis of related character shapes and examples within the Mawangdui Yishu, where we can grasp the state of medicine pre-Huangdineijing. Methods : Etymology was determined through ancient character analysis, while examples of its usage and original texts were compared to extract their implications. For usage analysis, medical texts of later periods that contained similar verses or contents with the Mawangdui text were compared, through which similarities and changes in meaning of the word or verse were examined. Conclusions : While the term 'xieqi(邪氣, pathogenic qi)' had not yet been mentioned in the Mawangdui text, 'eqi(惡氣)' was used similarly. Wind[風], cold[寒], dampness[濕] were not only understood as terms referring to weather or climate but possible causes for disease. Meanwhile, there was lingering belief from the Shang(商) period that saw disease as God's punishment, which could be seen as transition phenomenon from superstition to rational thought. Through diseases 'wind disease[風病]' and 'bi(痹)', we could determine that medicine at the time was limited to the Yin-yang theory, having not yet integrated the Five phases perspective. Moreover, the possibility of other pathogenic qi elements, 'heat[暑]', 'dryness[燥]', and 'fire[火]' could be assumed to have been embedded in 'wenbing(溫病)'.

Thermal buckling of rectangular sandwich plates with advanced hybrid SMA/CNT/graphite/epoxy composite face sheets

  • Saeed Kamarian;Jung-Il Song
    • Advances in nano research
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    • v.14 no.3
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    • pp.261-271
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    • 2023
  • The present study follows three main goals. First, an analytical solution with high accuracy is developed to assess the effects of embedding pre-strained shape memory alloy (SMA) wires on the critical buckling temperatures of rectangular sandwich plates made of soft core and graphite fiber/epoxy (GF/EP) face sheets based on piecewise low-order shear deformation theory (PLSDT) using Brinson's model. As the second goal, this study compares the effects of SMAs on the thermal buckling of sandwich plates with those of carbon nanotubes (CNTs). The glass transition temperature is considered as a limiting factor. For each material, the effective ranges of operating temperature and thickness ratio are determined for real situations. The results indicate that depending on the geometric parameters and thermal conditions, one of the SMAs and CNTs may outperform the other. The third purpose is to study the thermal buckling of sandwich plates with advanced hybrid SMA/CNT/GF/EP composite face sheets. It is shown that in some circumstances, the co-incorporation of SMAs and CNTs leads to an astonishing enhancement in the critical buckling temperatures of sandwich plates.

An Empirical Study on the Effect of Inflation Targeting on PPP: Evidence From 19 OECD countries (물가안정목표제가 구매력평가에 미친 영향: 19개의 OECD 국가들을 대상으로)

  • Eun-Son Lim
    • Korea Trade Review
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    • v.47 no.5
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    • pp.75-93
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    • 2022
  • Purchasing Power Parity (hereafter, PPP) means the purchasing power of two currencies is the same when one is converted into the other one. According to previous studies on PPP, as the volatility of the real exchange rate is smaller, PPP may be more likely to hold. Since New Zealand adopted the inflation targeting policy in December 1989, many countries started to adopt it as their monetary policy frame. Previous studies on inflation targeting found that inflation targeting policy has positive effects on not only achieving price stability but also reducing the volatility of nominal/ real exchange rates. Therefore, in this study, I explored whether inflation targeting policy has positive effects on purchasing power parity subject to 19 OECD countries, applying an Exponential Smooth Transition Autoregressive (ESTAR) model during the sample periods, from 1974:Q1 to 2019:Q4. Based on the ESTAR estimate results, I found limited favorable evidence of PPP for only two countries- England and Switzerland- among 9 inflation targeters, compared to non-inflation targeters, and also I found that favorable evidence of PPP only for these two countries among 9 inflation targeters during post-inflation targeting, but not during pre-inflation targeting. These findings imply that the positive effects of inflation targeting on PPP may be questionable unlike Ding and Kim (2012) and Kim (2014)'s study.

Association of a Pre-miR-27a Polymorphism with Cancer Risk: an Updated Meta-analysis

  • Bai, Rong-Pan;Weng, Yu;Su, Li-Ling;Jin, Ming-Juan;Xu, Zheng-Ping;Lu, Li-Qin;Chen, Guang-Di
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10107-10114
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    • 2015
  • MicroRNA-27a is highly expressed in cancers and has been identified as an oncogenic microRNA. A genetic variant in pre-miR-27a (rs895819) with a transition of A to G has been demonstrated to be associated with cancer risk; however, the results of these studies remain conflicting rather than conclusive. Therefore, we performed a meta-analysis to derive a more precise estimation. Through searching PubMed or other databases up to March 2014 using the following MeSH terms and keywords, "miR-27a", "polymorphism" and "cancer", seventeen case-control studies were identified in this meta-analysis, including 7,813 cases and 9,602. Crude odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were calculated to investigate the association strength between rs895819 and the susceptibility of cancer. The results of the overall meta-analysis did not suggest any association between rs895819 polymorphism and cancer susceptibility, and this remained in Asians as a subgroup. In Caucasians, however, the rs895819 was associated with a reduced cancer risk in heterozygous (OR, 0.83; 95%CI, 0.75-0.93) and dominant models (OR, 0.84; 95%CI, 0.76-0.93), and the [G] allele of rs895819 showed a protective effect (OR, 0.90, 95%CI, 0.84-0.97). Further studies showed a significant association between the [G] allele of rs895819 and decreased risk of breast cancer (0.91; 95%CI, 0.85-0.98), and stratified analyses indicated a protective effect of the [G] allele in Caucasians (OR, 0.89; 95%CI, 0.82-0.98), younger breast cancer cases (OR, 0.87; 95%CI, 0.79-0.96), and in the group of unilateral breast cancer patients (OR, 0.90; 95%CI, 0.83-0.97). These findings suggest an association between pre-miR-27a polymorphism rs895819 and cancer risk in Caucasians. The protective effect of rs895819 [G] allele in younger breast cancer and in the group of unilateral breast cancer patients await further confirmation since the included studies in this meta-analysis were limited.

Characterization of Genes Related to the Cell Size Growth and CCN Family According to the Early Folliculogenesis in the Mouse (쥐의 초기 난포 발달에 관여하는 Cell Size Growth 및 CCN Family 유전자에 관한 연구)

  • Kim, Kyeoung-Hwa;Park, Chang-Eun;Yoon, Se-Jin;Lee, Kyung-Ah
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.3
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    • pp.269-277
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    • 2005
  • Objectives: Previously, we sought to compile a list of genes expressed during early folliculogenesis by using cDNA microarray to investigate follicular gene expression and changes during primordialprimary follicle transition and development of secondary follicles (Yoon et al., 2005). Among those genes, a group of genes related to the cell size growth was characterized during the ovarian development in the present study. Methods: We determined ovarian expression pattern of six genes related to the cell size growth (cyr61, emp1, fhl1, socs2, wig1 and wisp1) and extended into CCN family (${\underline{c}}onnective$ tissue growth factor/${\underline{c}}ysteine$-rich 61/${\underline{n}}ephroblastoma$-overexpressed), ctgf, nov, wisp2, wisp3, including cyr61 and wisp1 genes. Expression of mRNA and protein according to the ovarian developmental stage was evaluated by in situ hybridization, and/or semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR), and immunohistochemistry, respectively. Results: Among 6 genes related to the cell size growth, cyr61 and wisp1 mRNA was detected only in oocytes in the postnatal day5 mouse ovaries. cyr61 mRNA expression was limited to the nucleolus of oocytes, while wisp1 was expressed in the cytoplasm and nucleolus of oocytes, except nucleus. cyr61 mRNA expression, however, was found in granulosa cells from secondary follicles. The rest 4 genes in the cell size growth group were detected in oocytes, granulosa and theca cells. Cyr61 and Wisp1 proteins were expressed in the oocyte cytoplasm from primordial follicle stage. Especially, Cyr61 protein was detected in pre-granulosa cells, Wisp1 protein was not. By using RT-PCR, we evaluated and decided that Cyr61 protein is produced by their own mRNA in pre-granulosa cells that was not detected by in situ hybridization. cyr61 and wisp1 genes are happen to be the CCN family members. The other members of CCN family were also studied, but their expression was detected in oocytes, granulose and theca cells. Conclusions: We firstly characterized the ovarian expression of genes related to the cell size growth and CCN family according to the early folliculogenesis. Cyr61 protein expression in the pre-granulosa cells is profound in meaning. Further functional analysis for cyr61 in early folliculogenesis is under investigation.