• Mass Spectrometry Letters
• /
• v.8 no.4
• /
• pp.90-97
• /
• 2017

Androgenic anabolic steroids (AASs) are synthetic derivatives of testosterone with a common structure containing cyclopentanoperhydrophenanthrene nucleus. Their use enhances the muscle building capacity and is beneficial during performance. The AASs are one of the most abused group of substances in horse doping. Liquid chromatography tandem mass spectrometry ($LC/MS^n$) has been successfully applied to the detection of anabolic steroids in biological samples. However, the saturated hydroxysteroids viz: nandrolone, $5{\alpha}-estrane-3{\beta}$, $17{\alpha}-diol$ exhibit lower detection responses in electrospray ionisation (ESI) because of their poor ionisation efficiency. To overcome this limitation pre-column chemical derivatization has been introduced to enhance their detection responses in $LC-ESI-MS^n$ analysis. The aim of present study was to develop a sensitive method for identification and confirmation of nandrolone and its metabolite in horse urine incorporating pre-column derivatization using picolinic acid. The method consists of extraction of targeted steroid conjugates by solid phase extraction (SPE). The eluted steroid conjugates were hydrolysed by methanolysis and free steroids were recovered with liquid-liquid extraction. The resulting steroids were derivatized to form picolinoyl esters and identification was done using LC-ESI-MS/MS in positive ionization mode. The picolinated steroid adduct enhanced the detection levels in comparison to underivatized steroids.

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.22 no.6
• /
• pp.443-450
• /
• 2022

Background: This double-blind randomized controlled trial (RCT) was conducted to evaluate the pre-emptive analgesia and anti-inflammatory efficacy of piroxicam compared with tramadol in patients undergoing oral surgery. Methods: Seventy-eight patients who required extraction of impacted mandibular third molars were randomized into three treatment groups of 26 patients each: group I received 100 mg of tramadol, group II received 20 mg of piroxicam, and group III received a placebo. Drugs were administered intramuscularly 30 min prior to the extraction procedure. Results: Pain intensity, time to first analgesic administration, total analgesic consumption, facial edema, and trismus were the outcomes of interest. The group receiving 20 mg of piroxicam showed significantly lower pain intensity, increased time to first analgesic, and reduced edema from preoperative to postoperative day seven than those in the tramadol and placebo groups. Conclusion: The findings of this study showed that piroxicam had significant pain relief efficacy after third molar surgery compared with that in tramadol.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.33 no.4
• /
• pp.375-380
• /
• 2007

The purpose of this study is to understand anxiety in patients undergoing third molar extraction and care patients of third molar extraction. The subjects in the study were Sixty-three patients who visited the department of dentistry at Pusan Paik Hospital from May 2006 to September 2006 and who underwent third molar extraction. Patients' anxiety(state anxiety and trait anxiety) to use Spielberger's state-trait anxiety inventory(STAI) were measured. They were asked to fill out STAI question paper immediately before third molar extraction(pre-extraction) and on the day after the extraction(post-extraction). And visual analog scale(VAS) to measure patient's postoperative pain on the day after extraction(postextraction day) was used. Then Differences in anxiety before and after extraction, between men and women, between the first and second extraction, with impacted versus non impacted third molar extraction, between extraction time and anxiety, and between postoperative pain and anxiety were evaluated. The anxiety status of patients undergoing third molar extraction could be quantitatively evaluated using the STAI-KYZ. There were significant difference before and after third molar extraction. Especially women and patients of more severe postoperative pain was more anxious. We need to alleviate patient's anxiety(especially women) and to control postoperative pain throughout the tooth removal process.

• YAKHAK HOEJI
• /
• v.46 no.6
• /
• pp.392-397
• /
• 2002

A simple and sensitive high performance liquid chromatographic method to quantitate ursodeoxycholic acid in crude drug pharmaceuticals was investigated. Ursodeoxycholic acid react with 2-bromoacetyl-6-methoxynaphthalene (Br-AMN) in the presence of triethylamine to form highly fluorescent derivative. The derivatization procedure was performed at 7$0^{\circ}C$ and completed within 30 min. The optimal wavelength of the fluorescence detector are λ$_{ex}$=300 nm and λ$_{em}$ = 460 nm. The LOD of the ursodeoxycholic acid was 25 ng/mι based on the S/N =3, and the LOQ was 80 ng/mι based on S/N = 10. Crude drug pharmaceuticals pretreated by solid phase extraction (Sep-pak $C_{18}$ cartridge) which were shown very good separation and recovery values for the compound.d.

• Journal of Korea Multimedia Society
• /
• v.21 no.8
• /
• pp.960-968
• /
• 2018

The mobile visual search service uses a query image to acquire linkage information through pre-constructed DB search. From the standpoint of this purpose, it would be more useful if you could perform a search on a web-based keyword search system instead of a pre-built DB search. In this paper, we propose a representative query extraction algorithm to be used as a keyword on a web-based search system. To do this, we use image classification labels generated by the CNN (Convolutional Neural Network) algorithm based on Deep Learning, which has a remarkable performance in image recognition. In the query extraction algorithm, dictionary meaningful words are extracted using Wikipedia, and hierarchical categories are constructed using WordNet. The performance of the proposed algorithm is evaluated by measuring the system response time.

• Journal of Korea Technical Association of The Pulp and Paper Industry
• /
• v.34 no.2
• /
• pp.67-72
• /
• 2002

The two stage laccase-assisted delignification process led to significant lignin removal in the non-pressurized treatments. It is clearly shown that an alkaline extraction prior to the second laccase treatment significantly increased the overall delignification by ∼15%. This is in line with the contention that the residual lignin has undergone structural changes during the alkaline extraction, and the resulting modified structures are susceptible to the laccase oxidation. In phenolic hydroxyl group, the pre- methylated sample was very responsive to the delignification process. The phenolic hydroxyl groups could be increased during side chain cleavage catalyzed by laccase. This finding demonstrates that the delignification oi etherified structures is an important reaction in the delignificaton by laccase.

• Proceedings of the KIEE Conference
• /
• 2002.11c
• /
• pp.529-532
• /
• 2002

This research treated development of real time pitch tracer for training of musical tune of speech signal and pre-processing and post-processing technics were proposed to get higher accuracy in extraction of pitch. Autocorrelation Function was used to get pitch frequency from 64Hz to 980Hz in real time. Half Rectifier method and Envelop extraction method as a pre-processing was used to get higher accuracy in pitch detection, and improved results were obtained on noised speech signal. Post-processing method using periodicity of Autocorrelation was proposed to get higher accuracy in the high frequency region.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.20 no.3
• /
• pp.429-437
• /
• 1996

This paper surveys extraction condition-temperature, pH, and changes of adsorbance in accordance with extraction condition of curcuma Longa L. solution. Using extracted curcuma Longa L. Solution, dyeing behaviors with natural fiber, effect of mordants to color fastness and color change were investigated. It was found that the amount of absorption (K/S value) was increased by mordants (Fe, Cr) and mordants treatment affected color change of dyed fabric. Among the mordants, effect of citric acid to color change of dyed fabric was the smallest, and color difference of post- mordant treatment is smaller than that of pee-mordant treatment in making use of citric acid as mordant. And K/S value of post mordant was higher than that of pre mordant. It was found that the pre - and post- mordants treatment little affected color fastness, but affected the amound of adsorption and color change of dyed fabric.

• International Journal of Computer Science & Network Security
• /
• v.23 no.1
• /
• pp.125-139
• /
• 2023

Facial expression recognition, a topical problem in the field of computer vision and pattern recognition, is a direct means of recognizing human emotions and behaviors. This paper first summarizes the datasets commonly used for expression recognition and their associated characteristics and presents traditional machine learning algorithms and their benefits and drawbacks from three key techniques of face expression; image pre-processing, feature extraction, and expression classification. Deep learning-oriented expression recognition methods and various algorithmic framework performances are also analyzed and compared. Finally, the current barriers to facial expression recognition and potential developments are highlighted.

• Journal of Environmental Health Sciences
• /
• v.25 no.3
• /
• pp.103-107
• /
• 1999

Even if odorous compounds remain very low concentration in water, it cause strong odor. Because Geosmin and most of odorous compound had very low vaporization, those were difficult to analyze with GC/MSD and Purge & Trap. So, we needed pre-treatment method for decreasing amounts of extracting solvents, improving recovery efficiencies and increasing analytical efficiencies. This study developed efficient technology for analyzing odorous compounds, using various adsorbents and extracting solvents. The optimum adsorbent was XAD resins. Especially, XAD-2, XAD-7 and XAD-2010 were superior, but XAD-2 of these and the optimum extraction solvent is MTBE. Other extraction solvents' efficiency is in order of MTBE>Dichloromethane>n-Hexane>Diethylether. The optimum NaCl dosage for increasing efficiency is 5 g in liquid-liquid extraction method. The shaking time(0~24hr) has no concern with adsorption efficiency. The optimum adsorbent is XAD-2 resin and extraction solvent is MTBE. Dosing NaCl, adsorption efficiency is increased in liquid-liquid extraction method, but NaCl has no effect on liquid-solid extraction method. In this experimental results, this algae toxins(Mycrocystin, Anatoxin etc.).