• Title/Summary/Keyword: pre-evaluation

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Captopril $^{99m}Tc-DTPA$ Renal Scintigraphy in Diagnosis of Renovascular Hypertension (신혈관성 고혈압의 진단에 있어서 캅토프릴 신스캔의 의의)

  • Yang, Hyung-In;Lee, Dong-Soo;Kim, Sung-Chul;Bae, Sang-Kyun;Choi, Chang-Woon;Chung, June-Key;Kim, Suhng-Gwon;Lee, Myung-Chul;Lee, Jung-Sang;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.2
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    • pp.312-317
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    • 1992
  • To evaluate the sensitivity and specificity of captopril renal scan for renovascular hypertension, we employed the captopril renal scan in conjunction with renal angiography in 81 patients, 159 kidneys, who were referred to evaluate the cause of hypertension. We defined the renovascular hypertension by the criteria of demonstration of renal artery stenosis by angiography, and improvement or cure of hypertension by revascularization. Visual and quantitative evaluation of $^{99m}Tc-DTPA$ renal scan was peformed pre and post captopril administration. The prevalence rate of renovascular hypertension was 40% in comparing with renal angiography, and 70% in confirmed cases. The causes of renovascular hypertension in 81 patients were Takayasu's arteritis, fibromuscular dysplasia, atherosclerosis, essential hypertension, chronic pyetonephritis etc. The sensitivity and specificity of captopril renal scan in comparing with renal angiography were 80%, 86.5%, respectively and also 84.2%, 72.6% in confirmed cases of renovascular hypertension, respectively. The causes of false negative cases were nonfunctioning kidney due to complete obstruction or long duration of disease in basal scan, segmental branch artery stenosis, unknown causes, and suspicious true negative cases without confirmation. The false positive cases were abdominal aortic stenosis or aneurysm, dehydration, unknown causes, and suspicious true positive cases. We conclude that captopril renal scintigraphy is highly sensitive, reasonably specific diagnostic method and comparable to other techniques very favorably.

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The Study of Characteristics of Cosmetic Powder by Using Various Grinding mill (화장품용 분체의 분쇄방식에 따른 특성연구)

  • Shim, Seung-Bo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.2
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    • pp.500-507
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    • 2008
  • By Using various grinding mill in powder cosmetics manufacturing process; screen milt and pin mill, jet mill, properties of the powder and grinding mills were studied; talc, mica, nylon powder, silica, titanium dioxide. Besides, the experiments fur evaluation of grinding were performed by using iron oxides those are tracers. In powders of plate shape, they were grinded more vertically than horizontally at the screen mill and pin mill, although were all grinded vertically and horizontally at the jet mill. The spheric powders became the primary particles or aggregation by electrostatic interaction at the screen mill and pin mill. But, at the jet mill, they resulted the agglomeration or transformation or damage up to 2bar. Titanium dioxides became the primary particles by all grinding mill. Pin mill has an excellent result in experiments which is a change of the tone of color by grinding. From these results, suggest that the jet mill is used to pre-treat of powders of plate shape in practical cosmetic manufacturing process, and the screen mill and pin mill are used to match the color of powder cosmetics. If industrial process condition is taken into consideration, suggest that 4times of grinding is excellent on grinding effect by the screen mill, and twice grinding by the pin mill and grind air pressure of 1bar by the jet mill.

Single-tube nested reverse transcription-polymerase chain reaction for simultaneous detection of genotyping of porcine reproductive and respiratory syndrome virus without DNA carryover contamination (DNA 교차오염 방지기능이 있는 single-tube nested reverse transcription-polymerase chain reaction을 이용한 돼지생식기호흡기증후군바이러스 유전형 감별진단)

  • Jeong, Pil-Soo;Park, Su-Jin;Kim, Eun-Mi;Park, Ji-Young;Park, Yu-Ri;Kang, Dae-Young;Cha, Hyun-Ouk;Lee, Kyoung-Ki;Kim, Seong-Hee;Park, Choi-Kyu
    • Korean Journal of Veterinary Service
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    • v.39 no.2
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    • pp.107-116
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    • 2016
  • In the study, we developed and evaluated a uracil N-glycosylase (UNG)-supplemented single-tube nested reverse transcription-polymerase chain reaction (UsnRT-PCR) assay that can carried out first-round RT-PCR and second-round nested PCR in a reaction tube without reaction tube opening and can simultaneously detect EU- and NA-PRRSV. The UsnRT-PCR confirmed to have a preventing ability of mis-amplification by contamination of pre-amplified PRRSV DNA from previous UsnRT-PCR. Primer specificities were evaluated with RNAs extracted from 8 viral strains and our results revealed that the primers had a high specificity for both genotypes of PRRSV. The sensitivity of the UsnRT-PCR was 0.1 $TCID_{50}$/0.1 mL for EU- or NA-PRRSV, respectively, which is comparable to that of previously reported real time RT-PCR (RRT-PCR). Clinical evaluation on 110 field samples (60 sera and 50 lung tissues) by the UsnRT-PCR and the RRT-PCR showed that detection rates of the UsnRT-PCR was 70% (77/110), and was relatively higher than that of the RRT-PCR (69.1%, 76/110). The percent positive or negative agreement of the UsnRT-PCR compared to RRT-PCR was 96.1% (73/76) or 90.9% (30/33), showing that the test results of both assays may be different for some clinical samples. Therefore, it is recommend that diagnostic laboratory workers use the two diagnostic assays for the correct diagnosis for the relevant samples in the swine disease diagnostic laboratories. In conclusion, the UsnRT-PCR assay can be applied for the rapid, and reliable diagnosis of PRRSV without concerns about preamplified DNA carryover contamination that can occurred in PCR process in the swine disease diagnostic laboratories.

Evaluation of Surgical Outcome with Pre-and Post-operative Rest/Acetazolamide Tc-99m HMPAO SPECT in Children with Moyamoya Disease (어린이 모야모야병에서 휴식/아세타졸아미드 Tc-99m-HMPAO SPECT를 이용한 수술결과 평가)

  • Lee, D.S.;Hyun, I.Y.;Wang, K.C.;Cho, B.K.;Chung, J.K.;Lee, M.C.
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.4
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    • pp.314-324
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    • 1998
  • Purpose: This study was performed to evaluate the outcome of encephalo-duro-arterio-synangiosis (EDAS) surgery with rest/acetazolamide Tc-99m HMPAO SPECT in moyamoya disease. Materials and Methods: Rost/acetazolamide subtraction SPECT with consecutive acquisition were done before and 2 months after 21 EDAS surgeries in 18 patients. Perfusion decrease was graded visually for 14 areas of each hemisphere as 0 (normal) to 3 (defect) using 4 point scoring system. Postoperative rest perfusion or perfusion reserve was compared with preoperative ones. Results: Among 294 areas of 21 hemispheres, rest perfusion abnormality was found in 91 areas of 15 hemispheres. Decrease of perfusion reserve was found in 146 areas of 18 hemispheres. Six hemispheres having normal rest perfusion and 12 of 15 hemispheres having rest perfusion abnormality showed reserve decrease. Three having rest perfusion defect did not change after acetazolamide in preoperative SPECT. After operation, 16 patients (89%) demonstrated clinical improvement. Fifteen among 18 hemispheres (83%) with decreased reserve improved. Rest perfusion abnormality improved in 6 among the 15 hemispheres (40%). The areas having rest perfusion and/or reserve decrease improved in 87 among 146 areas (60%). Decrease of reserve, improved in 85% (68/80). However, areas without reserve decrease also improved in 29% (19/66). The better was preoperative rest perfusion in involved areas or the more decreased vascular reserve, the more improved perfusion and reserve after operation. Conclusion: We conclude that assessment of perfusion and Perfusion reserve using rest/acetazolamide brain perfusion SPECT predict the surgical outcome in patients with moyamoya disease.

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Correlation of the Consolidation Characteristics of Inland and Harbour District Soil (육상 및 항만지역상의 압밀특성치의 상관성)

  • 도덕현;이성태;강우묵
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.25 no.4
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    • pp.50-60
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    • 1983
  • 305 samples of alluvial deposit in inland and harbour districts were selected and consolidation charateristics of the alluvium were put in order statiscally. The correlations between them were as follows. 1. The relationships between LL(liguid limit) and Cc (compression index) were explained as Cc=0. 03(LL-21. 7) in case of inland district soil and as Cc=0. 019(LL-19) in case of harbour district soil. As compared with formular proposed by Skernpton, the gradient of this linear line was slight steep. 2. The relationships between PI(plastic index) and Cc were explained as Cc=0. 063 PI-0. 52 in case of inland district soil and Cc=0. 043 PI-0. 31 in case of harbour district soil. 3. As void ratio and natural moisture content were increased, Cc was increased, and as wet density was increased, Cc was decreased with a gentle curve. 4. As LL and P1 increased, mv(coefficient of volume compressibility) was increased but if LL and P1 was increased beyond a certain extend, mv has a tendency of constant value, that is, mv show a tendency to take constant value in the very soft clay. and mv in P=2. 5kg/cm$^2$ was about l${\times}$ l0-$^1$cm$^2$/kg in case of land district soil and 6x 10-$^1$crn$^2$/kg in case of harbour district soil lower than that in P=0. 25kg/crn2. 5. Cv(coefficient of consolidation) was a tendency to decrease with a gentle curve as LL was increased, and Cv in P=0. 25kg/crn2 was about 3x l0-$^1$crn$^2$/min larger than that in P=2. 5kg/crn$^2$. 6. Relationships between Py(pre-consolidation pressure) which is included over consolidation soil and ∑r1h(effective over-burden pressure) were explained as Py=l. 12 ∑r'h in case of land district soil and as Py=l. l5∑r'h in case of harbour district soil. 7. Some of the properties show good correlations between them, practical and effective applications of these correlations are expected in the planning and excution of soil investigation and also in the evaluation of the results.

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Design and Evaluation of an Edge-Fog Cloud-based Hierarchical Data Delivery Scheme for IoT Applications (사물인터넷 응용을 위한 에지-포그 클라우드 기반 계층적 데이터 전달 방법의 설계 및 평가)

  • Bae, Ihn-Han
    • Journal of Internet Computing and Services
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    • v.19 no.1
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    • pp.37-47
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    • 2018
  • The number of capabilities of Internet of Things (IoT) devices will exponentially grow over the next years. These devices may generate a vast amount of time-constrained data. In the context of IoT, data management should act as a layer between the objects and devices generating the data and the applications accessing the data for analysis purposes and services. In addition, most of IoT services will be content-centric rather than host centric to increase the data availability and the efficiency of data delivery. IoT will enable all the communication devices to be interconnected and make the data generated by or associated with devices or objects globally accessible. Also, fog computing keeps data and computation close to end users at the edge of network, and thus provides a new breed of applications and services to end users with low latency, high bandwidth, and geographically distributed. In this paper, we propose Edge-Fog cloud-based Hierarchical Data Delivery ($EFcHD^2$) method that effectively and reliably delivers IoT data to associated with IoT applications with ensuring time sensitivity. The proposed $EFcHD^2$ method stands on basis of fully decentralized hybrid of Edge and Fog compute cloud model, Edge-Fog cloud, and uses information-centric networking and bloom filters. In addition, it stores the replica of IoT data or the pre-processed feature data by edge node in the appropriate locations of Edge-Fog cloud considering the characteristic of IoT data: locality, size, time sensitivity and popularity. Then, the performance of $EFcHD^2$ method is evaluated through an analytical model, and is compared to fog server-based and Content-Centric Networking (CCN)-based data delivery methods.

Evaluation of Chemical Pre-treatment for the Optimization of CO2 Fixatiom Using by Carbonation Reaction with Serpentine (이산화탄소 광물고정화 효율 증가를 위한 사문석의 화학적 전처리에 관한 연구)

  • Jang, Na Hyung;Shim, Hyun Min;Hua, Xu Li;Kim, Hyung Teak
    • Applied Chemistry for Engineering
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    • v.19 no.5
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    • pp.526-532
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    • 2008
  • The proposed $CO_2$ storage technology in the present study is a one-step sequestration process that stabilizes $CO_2$ in a reactor with Serpentine. The advantage of this technology is associated with its high stability of final product so that the entire system is recognized as permanent environment-friendly $CO_2$ removal method. Since the sequestration reaction mechanisms are generally understood that carbonation reaction proceeds with very slow rate, so that pretreatment method to increases reaction rate of $CO_2$ carbonation reaction should be developed. To increase the reactivity of Serpentine with $CO_2$, two different methods of pretreatment are carried out in the present investigation. One is heat-treatment, the other is chemical pretreatment. In this study, only chemical pretreatment is considered leaching method of magnesium from Serpentine using sulfuric acid at the various reaction temperatures, times, and acid concentrations. Experimental results illustrated that pretreatment by sulfuric acid increases surface area of serpentine from $11.1209m^2/g$ to $98.7903m^2/g$ and extracts magnesium compounds. Single variable experiment demonstrated the enhancements of magnesium extraction with increased reaction temperature and time. Amount of magnesium extraction is obtained by using the data of ICP-AES as maximum extraction condition of magnesium is 2 M acid solution, $75^{\circ}C$ and 1hr. After performing chemical pretreatment, carbonation yield increased from 23.24% to 46.30% of weight.

Effect of Different Pre-treatments on the Physicochemical and Antioxidant Activities of Cold-Vacuum Dried Peaches (전처리조건에 따른 냉풍감압건조 복숭아의 이화학적 및 항산화 활성)

  • Kwon, Gi-Man;Kim, Jae-Won;Youn, KwangSup
    • Korean Journal of Food Science and Technology
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    • v.45 no.4
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    • pp.466-472
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    • 2013
  • This study was performed to determine the effects of the pretreatment and cold-vacuum drying methods on the physicochemical properties and antioxidant activities of dried peaches. Moisture content was significantly lower with 0.3% NaCl treatment with cold-vacuum drying. The pH, brix and acid ratio (SS/TA) were the lowest with 1.0% soluble Ca treatment, while soluble solid and SS/TA were significantly higher with 0.1% vitamin C treatment compared to those with other treatments. The ${\delta}E$ and browning degree was lower in the pretreated sample compared to the untreated sample. Cutting strength of dried peaches was highest in the pretreated samples, and it was the highest with 1.0% soluble Ca treatment. Total sugar content with 0.1% vitamin C and 1.0% soluble Ca treatment was significantly higher than that with 0.3% NaCl treatment. The free sugar content was lower with 0.3% NaCl treatment but it was higher with 0.1% vitamin C and 1.0% soluble Ca treatment. The sensory evaluation result was highest with 0.1% vitamin C treatment. Phenolic compounds and antioxidant ability were the highest with the 0.1% vitamin C and 0.1% soluble Ca treatment; all the dried peaches showed relatively high antioxidant activities. These results suggest that pretreatment can affect the quality of dried peaches, showing that cold-vacuum drying can be applied for the production of high quality dried peach products.

The effect of aroma foot spa on stress (아로마풋스파가 스트레스에 미치는 영향)

  • Lee, Yeon-Hee;Jong, Seo-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.5
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    • pp.2206-2211
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    • 2012
  • To identify the effect of the aroma foot spa on the stress, 12 university students with stress were divided into control group (6 subjects) and aroma foot spa group (6 subjects). Control group was not subjected to any kind of intervention while aroma foot spa group was subjected to 10 minutes of foot bath using 5% Juniper, lavender and lemon essential oil and 10 minutes of foot massage using massage cream during four weeks, two times per week. As for the evaluation method, brain wave was studied to measure the amount of change in stress. After measuring the change in the brain wave before and after the experiment, it was proven that the aroma foot spa group s Alpha wave (Z=-2.364, p<.05) and SMR wave (Z=-1.981, p<.05) were higher than those of the control group. Moreover, when the pre and post experiment results of the aroma foot spa group were measured, it was proven that the Theta wave (Z=-2.366, p<.05) decreased while Alpha wave (Z=-2.371, p<.05) increased. In other words, aroma foot spa that included foot bath using essential oil and foot massage increased Alpha wave which in turn influenced the brain wave due to increased blood circulation resulting from muscle relaxation. Moreover, SMR wave increase was closely related to the change in Alpha wave, which demonstrates that SMR wave increased due to stress alleviation. Accordingly, it may be possible to assume that aroma foot spa is effective in relieving stress.

Collapse Capacity Evaluation of Steel Intermediate Moment Frames Using Incremental Dynamic Analysis (비선형 증분동적해석을 통한 철골 중간모멘트 골조의 붕괴성능 평가)

  • Shin, Dong-Hyeon;Kim, Hyung-Joon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.2
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    • pp.9-20
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    • 2014
  • Steel intermediate moment frames (IMFs) have been generally used as seismic load resisting systems (SLRSs) of a building to provide resistances against strong ground shaking. However, most of low and mid-rise steel buildings in Korea were constructed during pre-seismic code era or before the introduction of well-organized current seismic codes. It has been recognized that the seismic performance of these steel IMFs is still questionable. In order to respond to such a question, this study quantitatively investigates the seismic capacities of steel IMFs. Prototype models are built according to the number of stories, the levels of elastic seismic design base shear and the ductilities of structural components. Also, the other prototype models employing hysteretic energy dissipating devices (HEDDs) are considered. The collapse mechanism and the seismic performance of the prototype models are then described based on the results obtained from nonlinear-static and incremental-dynamic analyses. The seismic performance of the prototype models is assessed from collapse margin ratio (CMR) and collapse probability. From the assessment, the prototype model representing new steel IMFs has enough seismic capacities while, the prototype models representing existing steel IMFs provide higher collapse probabilities. From the analytic results of the prototype models retrofitted with HEDDs, the HEDDs enhance the seismic performance and collapse capacity of the existing steel IMFs. This is due to the energy dissipating capacity of the HEDDs and the redistribution of plastic hinges.