• 한국지진공학회논문집
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• 제18권3호
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• pp.151-160
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• 2014

Probabilistic tsunami hazard analysis (PTHA) is based on the approach of probabilistic seismic hazard analysis (PSHA) which is performed using various seismotectonic models and ground-motion prediction equations. The major difference between PTHA and PSHA is that PTHA requires the wave parameters of tsunami. The wave parameters can be estimated from tsunami propagation analysis. Therefore, a tsunami simulation analysis was conducted for the purpose of evaluating the wave parameters required for the PTHA of Uljin nuclear power plant (NPP) site. The tsunamigenic fault sources in the western part of Japan were chosen for the analysis. The wave heights for 80 rupture scenarios were numerically simulated. The synthetic tsunami waveforms were obtained around the Uljin NPP site. The results show that the wave heights are closely related with the location of the fault sources and the associated potential earthquake magnitudes. These wave parameters can be used as input data for the future PTHA study of the Uljin NPP site.

• 생물정신의학
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• 제6권1호
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• pp.49-66
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• 1999

Polypharmacotherapy, both psychotropic and nonpsychotropic, is widespread in various situations including psychiatric hospitals and general hospitals. As the clinical practice of using more than one drug at a time increase, the clinician is faced with ever-increasing number of potential drug interactions. Although many interactions have little clinical significances, some may interfere with treatment or even be life-threatening. The objective of this review is evaluation for drug-drug interactions often encountered in psychiatric consultation. Drug interactions can be grouped into two principal subdivisions : pharmacokinetic and pharmacodynamic. These subgroups serve to focus attention on possible sites of interaction as a drug moves from the site of administration and absorption to its site of action. Pharmacokinetic processes are those that include transport to and from the receptor site and consist of absorption, distribution on body tissue, plasma protein binding, metabolism, and excretion. Pharmacodynamic interactions occur at biologically active sites. In psychiatric consultation, these two subdivisions of drug interactions between psychotropic drugs and other drugs are likely to happen. We gathered informations of the drugs used in physically ill patients who are consulted to psychiatric department in Korea University Hospital. And we reviewed the related literatures about the drug-drug interactions between psychotropic drugs and other drugs.

• BMB Reports
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• 제29권2호
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• pp.169-174
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• 1996

Yeast cytochrome c (cyt c) was modified at cysteine-102 with a thiol-specific spin label and its interaction with liposomes containing acidic phospholipids was studied by electron paramagnetic resonance (EPR) spectroscopy. Association of cyt c with liposomes resulted in a significant reduction in the mobility of the spin label and a fraction of cyt c even seemed to be immobilized. Based on a large spectral change upon binding and the proximity of the spin-label to lysine-86 and -87, we propose these two residues to be the potential binding site at neutral pH. The interaction is electrostatic in nature because the spectral changes were reversed by addition of anions. Dissociation of the bound cyt c by anions, however, became less effective as the lipid/protein ratio increased. This suggests a repulsive lateral interaction among the bound cyt c. Unlabeled cyt c molecules added to preformed cyt c-liposome complex displaced the bound (spin labeled) cyt c and the process was competitive and reversible.

• 대한한의학회지
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• 제29권2호
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• pp.133-150
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• 2008

Objective: This study was performed to examine Danggui (DG, Angelica gigas Nakai)'s potential activity for promoting axonal regeneration in the injured peripheral nerve. Methods: Using the sciatic nerve in the rats, DG extract 5 ${\mu}l$(10 mg/ml in 0.5% saline) was dripped into the injury site of the nerve. Results: DG treatment facilitated axonal elongation responses in the distal portion to the injury site. GAP-43 protein levels were upregulated by DG treatment in the injured nerve and also in the DRG, suggesting the induction of GAP-43 expression at gene expression level after nerve injury. Phospho-Erk1/2 protein levels were upregulated in the injured nerve area and also in the DRG, suggesting retrograde transport of phospho-Erk1/2 protein from the injury area to the cell body. Cdc2 protein levels were slightly upregulated by DG treatment. DG treatment increased the number of non-neuronal cells in the distal portion to the injury site. Conclusions: The present data suggest that DG is effective for enhanced axonal regrowth after sciatic nerve injury.

• 한국막학회:학술대회논문집
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• 한국막학회 1995년도 제3회 심포지움 (분리막 연구의 최신동향)
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• pp.57-71
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• 1995

A simple mathematical model for gacilitated mass transport with a fixed site carrier membrane was derived by assuming an instantaneous, microscopic concentration (activity) fluctuation, The concentration fluctuation, developed due to reversible chemical reaction between carrier and solute, could acuse the higher chemical potential gradient and the facilitated transport. For mathematical formulation, an analogy was employed between the mass transfer for the facilitated transport with fixed site carrier membrane and the electron transfer in a parallel resistor-capacitor (RC) circuit. For the single RC model, it was assumed that a single capacitor represented the total carrier and a solute could not inter-diffuse between matrix and carrier, allowing only two diffusional pathways, This assumption was relaxed by adopting a serial combination of the parallel RC circuit. Here, a solute diffuses in two elements (matrix or carrier) can exchange its pathway, exhibiting four diffusional pathways. The current models were examined against experimental data and the agreement was exceptional.

• Architectural research
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• 제21권4호
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• pp.111-116
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• 2019

The premise of this research is the recent advancement of Building Information Modeling(BIM) Technology and Laser Scanning Technology(3D Scanning). The purpose of the paper is to amplify the potential offered by the combination of BIM and Point Cloud Data (PCD) for structural analysis. Today, enormous amounts of construction site data can be potentially categorized and quantified through BIM software. One of the extraordinary strengths of BIM software comes from its collaborative feature, which can combine different sources of data and knowledge. There are vastly different ways to obtain multiple construction site data, and 3D scanning is one of the effective ways to collect close-to-reality construction site data. The objective of this paper is to emphasize the prospects of pre-scanning and post-scanning automation algorithms. The research aims to stimulate the recent development of 3D scanning and BIM technology to develop Scan-to-BIM. The paper will review the current issues of Scan-to-BIM tasks to achieve As-Built BIM and suggest how it can be improved. This paper will propose a method of coordinating and utilizing PCD for construction and structural analysis during construction.

• 한국농공학회:학술대회논문집
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• 한국농공학회 2005년도 학술발표논문집
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• pp.387-392
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• 2005

The research was performed to predict the potential landslide with roughness index. It was known that fractal dimension and surface area index can be represented the topography, specially when the natural slopes were rough or rugged. A test site was selected and fractal dimension and surface area index were calculated from the irregular triangle network. Fractal dimension were ranged between $2.016{\sim}2.046$ and surface area index $1.56E+07{\sim}2.59E+07$. Surface area index increased as fractal dimension increased. Slope stability was calculated by infinite slope stability analysis model and was compared to slope stability by fractal and surface area index. In the result, unsafe zones where slope stability is under 1.1 were $5.11{\sim}6.25%$ for the test site. It can be said that fractal dimension and surface area index are a good index to evaluate the slope stability because when fractal dimension and surface area index are greater, then stability of the site is more unsafe.

• Safety and Health at Work
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• 제6권1호
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• pp.39-45
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• 2015

Background: Health and safety (H&S) on a construction site can either make or break a contractor, if not properly managed. The usage of Building Information Modeling (BIM) for H&S on construction execution has the potential to augment practitioner understanding of their sites, and by so doing reduce the probability of accidents. This research explores BIM usage within the construction industry in relation to H&S communication. Methods: In addition to an extensive literature review, a questionnaire survey was conducted to gather information on the embedment of H&S planning with the BIM environment for site practitioners. Results: The analysis of responses indicated that BIM will enhance the current approach of H&S planning for construction site personnel. Conclusion: From the survey, toolbox talk will have to be integrated with the BIM environment, because it is the predominantly used procedure for enhancing H&S issues within construction sites. The advantage is that personnel can visually understand H&S issues as work progresses during the toolbox talk onsite.

• 한국태양에너지학회 논문집
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• 제28권3호
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• pp.45-52
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• 2008

In order to clarify characteristics of variation in wind energy over a long-term period, an investigation was carried out at Seoguang site on Jeju island. The wind data for 10 years from Automatic Weather System (AWS) were analyzed for each year. The variation in the annual energy production (AEP) for the 2 MW wind turbine was estimated through statistical work. The result shows that the range of the yearly average wind speed at 15 m above ground level for 10 years was from -22.6% to +13.7%, which is wider range than that in Japan. The coefficient of variation for the AEP was 22.7%, which is about twice of that for the yearly average wind speed. Therefore, for estimating the wind energy potential accurately at a given site, the wind data should be analyzed over a long-term period based on the data from the meteorological station.

• 한국지하수토양환경학회지:지하수토양환경
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• 제16권1호
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• pp.71-81
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• 2011

Cause of contamination in the study area nearby Jang Hang Refinery is dust scattering in refinery stack, and soil washing treatment is one of the proper technologies for soil remediation in this area. Site conditions frequently limit the selection of a treatment process. A treatment technology may be eliminated based on the soil classification or physicochemical characteristics of soil. This study was assessed the soil washing efficiency by conducting of soil characteristic analysis in the vicinity of Jang Hang Refinery Stack within a 2 km radius. Also, it was decided about remedial range with comparative analysis of As in soil by Korean Standard Test Method before/after revision, whereupon As concentration in soil showed a increasing tendency after revision. As a result, the soil washing using the size separation of soil was determined through identifying of As species in the soil. In this site, only particle size distribution and water content of soil can provide the initial means of screening for the potential use of soil washing.