• Proceedings of the National Institute of Ecology of the Republic of Korea
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• v.2 no.1
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• pp.1-14
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• 2021

The study has been carried out with an objective to prepare Siberian roe deer habitat potential maps in South Korea based on three geographic information system-based models including frequency ratio (FR) as a bivariate statistical approach as well as convolutional neural network (CNN) and long short-term memory (LSTM) as machine learning algorithms. According to field observations, 741 locations were reported as roe deer's habitat preferences. The dataset were divided with a proportion of 70:30 for constructing models and validation purposes. Through FR model, a total of 10 influential factors were opted for the modelling process, namely altitude, valley depth, slope height, topographic position index (TPI), topographic wetness index (TWI), normalized difference water index, drainage density, road density, radar intensity, and morphological feature. The results of variable importance analysis determined that TPI, TWI, altitude and valley depth have higher impact on predicting. Furthermore, the area under the receiver operating characteristic (ROC) curve was applied to assess the prediction accuracies of three models. The results showed that all the models almost have similar performances, but LSTM model had relatively higher prediction ability in comparison to FR and CNN models with the accuracy of 76% and 73% during the training and validation process. The obtained map of LSTM model was categorized into five classes of potentiality including very low, low, moderate, high and very high with proportions of 19.70%, 19.81%, 19.31%, 19.86%, and 21.31%, respectively. The resultant potential maps may be valuable to monitor and preserve the Siberian roe deer habitats.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10513-10524
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• 2015

Background: Metastasis is a major reason for poor prognosis in patients with cancer, including hepatocellular carcinoma (HCC). A salient feature is the ability of cancer cells to colonize different organs. Long non-coding RNAs (lncRNAs) play important roles in numerous cellular processes, including metastasis. Materials and Methods: In this study, the lncRNA expression profiles of two HCC cell lines, one with high potential for metastasis to the lung (HCCLM3) and the other to lymph nodes (HCCLYM-H2) were assessed using the Arraystar Human LncRNA Array v2.0, which contains 33,045 lncRNAs and 30,215 mRNAs. Coding-non-coding gene co-expression (CNC) networks were constructed and gene set enrichment analysis (GSEA) was performed to identify lncRNAs with potential functions in organ-specific metastasis. Levels of two representative lncRNAs and one representative mRNA, RP5-1014O16.1, lincRNA-TSPAN8 and TSPAN8, were further detected in HCC cell lines with differing metastasis potential by qRT-PCR. Results: Using microarray data, we identified 1,482 lncRNAs and 1,629 mRNAs that were differentially expressed (${\geq}1.5$ fold-change) between the two HCC cell lines. The most upregulated lncRNAs in H2 were RP11-672F9.1, RP5-1014O16.1, and RP11-501G6.1, while the most downregulated ones were lincRNA-TSPAN8, lincRNA-CALCA, C14orf132, NCRNA00173, and CR613944. The most upregulated mRNAs in H2 were C15orf48, PSG2, and PSG8, while the most downregulated ones were CALCB, CD81, CD24, TSPAN8, and SOST. Among them, lincRNA-TSPAN8 and TSPAN8 were found highly expressed in high lung metastatic potential HCC cells, while lowly expressed in no or low lung metastatic potential HCC cells. RP5-1014O16.1 was highly expressed in high lymphatic metastatic potential HCC cell lines, while lowly expressed in no lymphatic metastatic potential HCC cell lines. Conclusions: We provide the first detailed description of lncRNA expression profiles related to organ-specific metastasis in HCC. We demonstrated that a large number of lncRNAs may play important roles in driving HCC cells to metastasize to different sites; these lncRNAs may provide novel molecular biomarkers and offer a new basis for combating metastasis in HCC cases.

• Management & Information Systems Review
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• v.30 no.4
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• pp.315-338
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• 2011

A "high-potential employee" is an employee who has been identified as having the potential, ability and aspiration for successive leadership positions within the company and identify employees who have the greatest future potential and make them future-ready to take your organization to success. The primary purpose of this paper is to investigate the relationships of corporate performance on the high potential employee system using the samples from HCCP panel data. This study seeks to identify a significant high potential employee system though empirical research as well. Results of empirical study are summarized. Finally suggestions, implications and limitations of the present study are also discussed. In this article, we explore the role of competitive strategy and technological environment in the introduction of high-potential employees and its link to impact of these performance.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.3
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• pp.387-395
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• 2013

PURPOSE: The purpose of the present study was to investigate the effect of the training using Pedalo equipment on balance function in post-stroke patients. METHODS: The present study was case-series. Ten post-stroke patients participated in the study. Participants performed the training using Pedalo equipment. The training using four Pedalo equipment lasted 30 minutes, 3 times a week for 6 weeks. Force platform, Berg Balance Scale(BBS), and Timed Up and Go(TUG) test were used to assess balance ability before and after training. RESULTS: After training using Pedalo equipment, there were significantly improved on path length and sway velocity of post-stroke patients in the both of eye open and - close conditions comparing with baseline. Also, on the BBS and TUG, there were significant improvements after training. CONCLUSION: The results of this study showed that the training using Pedalo equipment may be effective on improving the balance ability in the post-stroke patients. Through this study, we were able to confirm the potential of training using Pedalo equipment as an intervention in the rehabilitation of post-stroke patients.

• Preventive Nutrition and Food Science
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• v.22 no.3
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• pp.216-222
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• 2017

Antioxidant rich green leafy vegetables including garden spinach leaf, water spinach leaf, Indian spinach leaf, and green leaved amaranth were selected to evaluate the effects of water boiling and oil frying on their total phenolic content (TPC), total flavonoid content (TFC), reducing power (RP), and antioxidant capacity. The results revealed that there was a significant increase in TPC, TFC, and RP in all the selected vegetables indicating the effectiveness of the cooking process on the antioxidant potential of leafy vegetables. Both cooking processes enhanced significantly (P<0.05) the radical scavenging ability, especially the oil fried samples showed the highest values. There is a significant reduction in the vitamin C content in all the vegetables due to boiling and frying except in the Indian spinach leaf. However, the present findings suggest that boiling and frying can be used to enhance the antioxidant ability, by increasing the bioaccessibility of health-promoting constituents from the four vegetables investigated in this study.

• Journal of Korean Foot and Ankle Society
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• v.8 no.1
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• pp.111-113
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• 2004

In neurogenic equinovarus deformity, surgical intervention such as tendon transfer or osteotomy can be expected to improve symptoms. However, in rare cases of hereditary spastic paraplegia, the deformity and paralysis gradually progress. So limited operation and early post-operative rehabilitation are preferred to aggressive operation. We would like to report our clinical experience with one case of hereditary spastic paraplegia patient with reference review. A 40 year-old male, given tendon transfer of ankle and foot and tendo achilles lengthening 10 years ago, complained about aggravated spastic paraplegia which resulted in dynamic equinovarus and limited walking ability since his operation. Family history showed limited walking ability of his father with gradually progressing spastic paralysis and he was diagnosed as hereditary spastic paraplegia type I. We had performed a limited operation such as tendo achilles and tibialis posterior lengthening to induce plantigrade standing and walking with crutch. As a result, the patient was able to maintain a stabilized standing posture and walk after the operation. Hereditary spastic paraplegia presents with a progressive paralysis which limits rehabilitation after tendon transfer, and the symptoms can be aggravated. Therefore, considering potential hereditary neurogenic disorders in paients with equinovarus deformity and performing limited operative procedures seem to be important.

• The KSFM Journal of Fluid Machinery
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• v.7 no.2 s.23
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• pp.41-49
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• 2004

Condition monitoring is very important in turbo machinery because single failure could cause critical damages to its plant. So, automatic fault recognition has been one of the main research topics in condition monitoring area. We have used a relatively new fault recognition method, Hidden Markov Model(HMM), for mechanical system. It has been widely used in speech recognition, however, its application to fault recognition of mechanical signal has been very limited despite its good potential. In this paper, discrete HMM(DHMM) was used to recognize the faults of rotor system to study its fault recognition ability. We set up a rotor kit under unbalance and oil whirl conditions and sampled vibration signals of two failure conditions. DHMMS of each failure condition were trained using sampled signals. Next, we changed the setup and the rotating speed of the rotor kit. We sampled vibration signals and each DHMM was applied to these sampled data. It was found that DHMMs trained by data of one rotating speed have shown good fault recognition ability in spite of lack of training data, but DHMMs trained by data of four different rotating speeds have shown better robustness.

• Journal of Korean Medical classics
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• v.29 no.1
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• pp.125-137
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• 2016

Objectives : Introduction to Medicine(醫學入門, Yixuerumen) is one of the basic clinical texts in Korean medical history. This study is designed to prove clinical value of Introduction to Medicine for practitioners in their early stage of clinical practice. Methods : Introduction to Medicine is closely reviewed in various aspects in order to examine broad outlines of specificity as well as its distinctive constructional feature. Results : Since Introduction to Medicine showed peculiar intention of developing practitioner's clinical ability, it has been a preferential choice for Korean medicine practitioners to enhance their qualification at the early stage of one's career in Korean history. It is still valid for modern practitioners because composite medical texts are needed in order to systematize one's fragmental knowledge acquired from institutional education. Conclusions : Introduction to Medicine shows a large potential as a clinical textbook in the course of maximizing one's clinical ability with its aid. Through understanding multilateral aspects of clinical guidelines and directions engraved in Introduction to Medicine, learners will be able to derive full capacity from the text.

• Toxicological Research
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• v.23 no.2
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• pp.115-121
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• 2007

Biotechnology is often described as the 'exploitation of biological processes for industrial purposes'. The last twenty years have seen phenomenal growth in this industry. The 21 century promises to see further advances in the field. However, since the cost of research is high, and the potential returns are linked to exclusivity, intellectual property protection is critical to this burgeoning industry. Without protection such investments in R&D would not be made and, the benefit that BT-related development are expected to bring, would not occur. BT industry are eager for high technology, and the technology must be transferred to a corporation from a research organization. In order to be successful, it is important that scientist must be directed toward R&D outcome beyond performance assessment. The process to gain a outcome involves multiple steps to turn the idea into the profit, and intellectual property issues are considered into the critical factors to affect the quality of R&D. The management of Intellectual property is very important in R&D. However, According to the survey conducted by KIIP (Korea Institute of Intellectual Property) and KOSEF (Korea Science and Engineering Foundation) in 2006, it is estimated the ability to treat Intellectual property is not sufficient because 82.5% of the respondents have not received an education. Governmental Support is needed to prompt systematically the ability of intellectual property management through education and consulting.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06a
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• pp.112-115
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• 2011

Healthcare is one of the biggest industries that consume IT Infrastructure as a necessity. A reliable reach to secure private information is the essential goal. Most of the healthcare organizations either have their own custom solutions developed or third part CRM software tailored to their needs. This culture satisfies the usability internal to the organization but lacks the ability to provide public access to the users or even to take a step ahead and collaborate with like minded institutes for research and potential growth. Emergence of cloud computing has provided us the opportunity to take a step ahead and build applications available to users on a secure platform, with ability to scale the resources depending on the requirements. The effective use of hybrid and community cloud can create rock solid foundations for healthcare IT Infrastructure. These cloud deployment models not only caters the present needs of healthcare IT Infrastructure but also opens the possibilities to build applications and provide secure and reliable access beyond the limits of organizational boundaries.