• 여성건강간호학회지
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• 제26권4호
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• pp.336-345
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• 2020

Purpose: This study aimed to identify factors influencing quality of life in post-menopausal women. Methods: The participants were 194 post-menopausal women who visited a women's clinic in Changwon, Korea from July 1 to August 31, 2018, and completed questionnaires containing items on menopausal symptoms, marital intimacy, current menopausal hormone therapy (MHT), and quality of life. Collected data were analyzed by descriptive statistics, the independent t-test, Pearson correlation coefficients, and multiple regression using SPSS for Windows version 23.0. Results: Quality of life had a significant negative correlation with menopausal symptoms (r=-.40, p<.001), and a significant positive correlation with marital intimacy (r=.54, p<.001). The factors influencing the quality of life of post-menopausal women were current MHT (t=6.32, p<.001), marital intimacy (t=4.94, p<.001), monthly family income (t=4.78, p<.001), menopausal symptoms (t=-4.37, p<.001), and education level (t=3.66, p<.001). These variables had an explanatory power of 59.2% for quality of life in post-menopausal women. Conclusion: In order to improve the quality of life of post-menopausal women, nursing interventions are needed to help menopausal women choose appropriate MHT, alleviate menopausal symptoms, and increase marital intimacy. Interventions should also be prioritized for women of a low educational level and with a low income in consideration of their health problems.

• 대한간호학회지
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• 제30권4호
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• pp.956-966
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• 2000

The purpose of this study was to examine the comparative between depression and stress related to life events among women in the menopausal stage. Menopausal stages were divided into two groups: Pre and post-menopausal stages. The degree of depression and stress related to life events between pre and post menopausal women were compared to each other. Women, aged between 41 and 59 years, answered self-reported questionnaires which included Zung's depression scale and life events scale modified by Lee (1984). Findings were as follows; 1) The mean score of premenopausal women who experienced depression was 39.66, and for post-menopausal women the score was 41.45. There was no significant differences in depression levels between pre and post menopausal group.s (t=-1.55, p=.122). 2) Menopausal women experienced low levels of stress related to life events. There were no significant differences between pre and post menopausal groups(t=.527, p>.05). Both pre and post menopausal groups were highly concerned about education issues of their children and disharmony between couples. 3) There was a significant relationship between depression and stress related to life events among post-menopausal groups (r=.22, p<.01). Based on the findings of this study, the menopausal depression was associated with stress related to life events, especially among post-menopausal women. Feelings of lost fertility and feminine attributies result in menopausal depression, which is significantly correlated with women's negative perception of their life events. Therefore, nursing intervention needs to develop to help reduce the levels of depression and overcome their negative perception of the menopausal experience. Nurses should develop nursing strategies to help menopausal women to have positive perceptions and enhance quality of life by assisting their adaptability to physiological and psychological changes related to menopause.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2327-2331
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• 2015

Purpose: To determine the accuracy of visual inspection with acetic acid (VIA) in detecting high-grade cervical intraepithelial neoplasia (CIN) in pre- and post-menopausal women with atypical squamous cells of undetermined significance (ASC-US) and low grade squamous intraepithelial lesion (LSIL) Papanicolaou (Pap) smears. Materials and Methods: Two hundred women (150 pre-menopausal and 50 post-menopausal) with ASC-US and LSIL cytology who attended the colposcopy clinic, Thammasat University Hospital, between March 2013 and August 2014 were included. All women underwent VIA testing and colposcopy by gynecologic oncologists. Diagnostic values of VIA testing including sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for detecting high-grade CIN were determined using the histopathology obtained from colposcopic-directed biopsy as a gold standard. Results: VIA testing was positive in 54/150 (36%) pre-menopausal women and 5/50 (10%) post-menopausal women. Out of 54 pre-menopausal women with positive VIA testing, 15 (27.8%) had high-grade CIN and 39 (72.2%) had either CIN 1 or insignificant pathology. Ten (10.4%), 43 (44.8%) and 43 (44.8%) out of the remaining 96 pre-menopausal women with negative VIA testing had high-grade CIN, CIN 1 and insignificant pathology, respectively. Out of 5 post-menopausal women with positive VIA testing, there were 4 (80%) women with high-grade CIN, and 1 (20%) women with insignificant pathology. Out of 45 VIA-negative post-menopausal women, 42 (93.3%) women had CIN 1 and insignificant pathology, and 3 (6.7%) had high-grade CIN. Sensitivity, specificity, PPV and NPV of the VIA testing were 59.4%, 76.2%, 32.2% and 90.8%, respectively (60%, 68.8%, 27.8% and 89.6% in pre-menopausal women and 57.1%, 97.7%, 80% and 93.3% in post-menopausal women). Conclusions: VIA testing may be used as a screening tool for detecting high-grade CIN in women with minor cervical cytological abnormalities in a low-resource setting in order to lower the rate of colposcopy referral.

• 대한간호학회지
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• 제41권2호
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• pp.191-196
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• 2011

Purpose: We investigated the effects of group III mechanoreceptors to cardiovascular responses in both pre-menopausal woman and post-menopausal woman during passive ankle dorsiflexion (PAD). Methods: Twenty healthy volunteers (10 post-menopausal women and 10 pre-menopausal women) were recruited for this study. Stroke volume (SV), heart rate (HR), cardiac output (CO), and total vascular conductances (TVC) were measured continuously throughout the experiment. To stimulate the group III mechanoreceptors, PAD was performed for one minute. Results: The results showed that mean arterial pressure (MAP) mediated by the mechanoreflex activation was significantly increased in both groups. However, this pressor response was significantly higher in post-menopausal women. This reflex significantly increased both SV and CO in pre-menopausal women, while there were no differences in post-menopausal women. There was no difference in HR in either group. The mechanoreflex significantly decreased TVC in post-menopausal woman, while there was no difference in pre-menopausal woman. Conclusion: The results indicate that the excessive pressor response mediated by the mechanoreflex occurs due to overactivity of group III mechanorecptors and the mechanism is produced mainly via peripheral vasoconstriction in post-menopausal women.

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6639-6641
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• 2014

Background: To evaluate the clinical significance of atypical squamous cells of undetermined significance (ASCUS) in PAP test in post-menopausal women and compare with reproductive age women. Materials and Methods: A total of 367 patients who referred to our gynecologic oncology clinic were included to the study between September 2012 and August 2013. Data for 164 post-menopausal (group 1) and 203 pre-menopausal (group 2) women with ASCUS cytology were evaluated retrospectively. Immediate colposcopy and endocervical curettage was performed for both groups and conization for all women with a result suggestive of CIN2-3. Histopathological results and demographic features of patients were compared between the two groups. Results: Mean age of the patients was $54.6{\pm}6.5$ years in group 1 and $38{\pm}6.6$ years in group 2. Some 14 (8.5%) of post-menopausal women and 36 (17.7%) of pre-menopausal women were current smokers (p=011). Totals of 38 (23.2%) post-menopausal and 64 (31.5%) pre-menopausal women were assessed for HPV-DNA. High risk HPV was detected in 7 (4.3%) and 21 (10.3%), respectively (p=0.029). Final histopathological results recorded were normal cervix, low grade cervical intra-epithelial neoplasia (CIN 1), and high grade cervical intra-epithelial neoplasia (CIN2-3). In group 1 results were 84.8%, 12.2% and 1.8%, respectively, and in group 2 were 71.9%, 23.2% and 4.9%. There were no cases of micro invasive or invasive cervical carcinoma in either group. Two cases were detected as endometrial carcinoma in the menopausal group (1.2%). Conclusions: In current study we found that preinvasive lesions were statistically significantly higher in pre-menopausal women than post-menopausal women with ASCUS. Cervicitis was more common in menopausal women. Therefore, we think that in case of ASCUS in a post-menopausal woman there is no need for radical management.

• 여성건강간호학회지
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• 제3권2호
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• pp.268-281
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• 1997

This study was done for the purpose of analysing the relationship between menopausal syndrome and depression in the pre and post menopausal women's group. Data were collected by a questionnaire from November, 1995 to December, 1996. The subject were 244 midlife women(94 subjects were in pre-menopausal period, 150 subject were in post-menopausal period). The instruments used for this study were the menopausal syndrome scale by Neugarton and depression scale by Zung. Data were analyzed with the SPSS/PC using frequency, t-test, and Pearson correlation coefficients. The results of this study were as follows ; 1. The most serious menopausal symptom in the midlife women was 'back pain and joint pain'. 2. The item of 'Hot flush'(t=-2.78, p<0.01), 'sweating'(t=-2.31, p<0.05) and 'nervousness'(t=-2.13, p<0.05) as menopausal syndromes were statistically significant in the two groups ; Post menopausal group were higher then premenopausal group. 3. Postmenopausal group were a little higher then premenopausal group as depression level. It was none statistically significant in the two groups. 4. The relationship between menopausal syndromes and the level of depression was statistically significant in the group of post-menopausal group(r=0.2083, p<0.01).

• 동아시아식생활학회지
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• 제27권4호
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• pp.408-419
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• 2017

This study was carried out to compare the relationship between biochemical indices and bone mineral density (BMD) in 50 pre-menopausal and 50 post-menopausal women. The subjects were divided into normal and risk groups according to their bone status, as determined by T-scores of the lumbar spine and femur. The average T-score of the lumbar spine was higher (p<0.05) in pre-menopausal women ($0.42{\pm}0.18$) than post-menopausal women ($-0.08{\pm}0.21$). Serum levels of HDL-cholesterol, P, and Fe were significantly higher in the risk group than the normal group in pre-menopausal women (p<0.05). Serum levels of total protein, globulin, alkaline phosphatase (ALP), and osteocalcin were lower in the risk group than the normal group, whereas the level of estrogen was higher in the normal group than the risk group in post-menopausal women (p<0.05). In pre-menopausal women, P was positively correlated with Ca (p<0.01), and ALP was positively correlated with osteocalcin (p<0.01) and parathyroid hormone (PTH) (p<0.05). Further, insulin-like growth factor-I (IGF-I) was negatively correlated with the vitamin $25(OH)D_3$ and vitamin K (p<0.05). In post- menopausal women, the Ca was positively correlated with vitamin $25(OH)D_3$ (p<0.05) and vitamin K (p<0.01), and P was positively correlated with vitamin K (p<0.01), Ca (p<0.01), and IGF-I (p<0.05) and negatively correlated with PTH (p<0.05). IGF-I was negatively correlated with PTH (p<0.01) and estrogen (p<0.05), and ALP was positively correlated with osteocalcin (p<0.01) and negatively correlated with vitamin K and estrogen (p<0.05). In pre-menopausal women, the lumbar spine BMD was positively correlated with vitamin K level (p<0.01) and negatively correlated with P level (p<0.05). In post-menopausal women, the femur BMD was positively correlated with estrogen level and negatively correlated with PTH leves (p<0.05). These results suggest that vitamin K and P levels are associated with bone health in pre-menopausal women, and estrogen and PTH levels are associated with bone health in post-menopausal women.

• 대한한방부인과학회지
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• 제24권3호
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• pp.116-126
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• 2011

Objectives: To identify the difference of autonomic nervous system activity in women with overactive bladder between women with pre-menopausal onset and post-menopausal onset. Methods: Total of 46 women with overactive bladder participated in this study. Patients were categorized in two groups, patients with pre-menopausal onset(n=31) and post-menopausal onset(n=15). We measured and compared parameters of Heart Rate Variability of patients. The results were analysed using SPSS for windows 12.0. Results: On frequency domain analysis, the patients with post-menopausal onset had significantly decreased mean value of Total Power, High Frequence, Low Frequence, compared with the patients with post-menopausal onset. Conclusion: Decreased Total Power of patients with post-menopausal onset indicated that they may have had decreased activity of autonomic nervous system. Also, the patients with pre-menopausal onset had relatively increased sympathetic activity than the patients with post-menopausal onset.

• 근관절건강학회지
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• 제19권3호
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• pp.263-271
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• 2012

Purpose: The purpose of this study was to examine the effects of line dance program on muscle strength, balance, flexibility, pain, and mood state in post-menopausal women. Methods: A quasi-experimental research design (one group pretest-posttest) was employed. A total of 13 post-menopausal women completed 12-week line dance program(60min/day, 2days/wk) in S city. Descriptive statistics, Wilcoxon signed rank test were used in the data analysis by SPSS 18.0. Results: Muscle strength and balance were higher, and pain level were lower than before the line dance program. However, flexibility and mood state were not significantly changed after the line dance program. Conclusion: Findings of this study indicated that the 12-week line dance program were effective on muscle strength, balance, and pain relief in the post-menopausal women. Future study is needed to explore the effect of the line dance program on flexibility and mood state with the post-menopausal women.

• 근관절건강학회지
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• 제18권2호
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• pp.158-168
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• 2011

Purpose: The purpose of this study was to compare musculoskeletal pain, menopausal symptoms and depression by women's menopausal stage. Method: With a survey design, a convenience sample of 203 women between age of 40 to 64 was recruited through a community. Data were collected via a structured study questionnaire from May to July, 2008. Measures included with symptom severity list for menopausal symptoms, Aches and Pains scale, and Beck's Depression Inventory. Results: Thirty-seven percent of women belong to early peri-menopausal stage, 31% to late peri-menopausal stage, and 32% to postmenopausal stage. By group comparison, late peri-menopausal and post menopausal women reported higher scores of depression than early peri-menopausal women. Postmenopausal women had greater scores in two pain subscales (bodily pain and pain that interferes with normal work) and two menopausal symptoms subscales (sleep pattern and sexual behaviors) than early peri-menopausal women. There were moderate levels of positive relationships among study variables at each menopausal stage. Conclusion: Postmenopausal women seem to have greater musculoskeletal pain and menopausal symptoms, and have depression more than did early peri-menopausal women. Tailored nursing strategies are required to reduce these kinds of common symptoms for women with menopausal transition to improve their physical and psychological wellbeing.