• Journal of Microbiology and Biotechnology
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• v.14 no.1
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• pp.134-139
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• 2004

Hybrid cluster protein (HCP) was investigated because of its unique iron-sulfur clusters, which have been found in bacteria and archaea. Here, HCP homologous proteins from the third domain, 'eukarya'(3 amitochondriate protozoans, Giardia lamblia, Entamoeba histolytica, and Trichomonas vaginalis), were identified. All three amitochondriate protozoan HCPs (GlHCP, EhHCP, and TvHCP) belonged to Class I on the basis of two key characters, the cysteine spacing, Cys-(Xaa)₂Cys(Xaa)/sub 7-8/-Cys(Xaa)/sub 5/-Cys, and the absence of N-terminal deletion characteristic to the Class III. In phylogenetic analysis performed with amino acid sequences of 3 eukaryal, 5 bacterial, and 4 archaeal HCPs, the maximum likelihood (ML) tree indicated that TvHCP was clustered with Class I HCPs, whereas the other two HCPs (GlHCP and EhHCP) formed an independent clade with a high bootstrapping value (96%) not belonging to any previously recognized HCP class. In spite of the relatively lower bootstrapping value (61%), the position of the new eukaryal GlHCP-EhHCP clade was close to Class I, including the TvHCP, and Classes II and III were closely related with each other. The finding of eukaryal HCPs would help to understand the evolutionary history of HCP.

• Journal of the Korean Society for Marine Environment & Energy
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• v.19 no.2
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• pp.129-136
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• 2016

Floating offshore structures keep its position by a mooring system against various kind of environmental loadings. For this reason, a reliable design of the mooring system is a key factor for initial design stage of a floating structure. However, there exists possibility of mooring failure, even the system is designed with enough safety margin, due to the unexpected extreme environmental conditions or long-term fatigue loadings. The breaking of one of the mooring lines may change the tension level of the other mooring lines, which can potentially result in a progressive failure of the entire structure. In this study, time domain numerical simulation of 10MW class wind-wave hybrid platform was carried out with partially broken mooring line. Overall platform responses and variations of the mooring line tension were numerically evaluated.

• Journal of Biomedical Engineering Research
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• v.20 no.6
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• pp.573-581
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• 1999

Although phonocardiography by auscultation has been used in diagnosis long time ago, recognition of heart sound was tried only restricted fields such as the first heart sound, the second heart sound, and specific valve operation for the purpose of analyzing local function or operation of heart and developments of heart sound recognition in full cycle are quite insignificant. in this paper, we proposed a recognition method which extracts features of heart sound in full cycle and classllies heart sounds This proposed recognition algorithm is based on detecting the first and second heart sounds in thme domain. The algorithm classifics heart sound into several classes by extracting the important time blocks and analyzing the peak position, integration values and statistical variables. Heart sounds are classified into normal, early systolic murmur, late systolic mumur, early diastolic murmur, late diastolie murmur, continuous murmur. We can verify our algorithm is useful from the results which show the average recognition rate of heart sounds is 88 perecnt. Recognition error was occurred mainly in early systolic murmur.

• Health Policy and Management
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• v.15 no.4
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• pp.110-135
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• 2005

The objectives of this study were (1) to describe doctors' perception and attitudes toward patient safety culture and medical error reporting in their working unit and hospitals, (2) to examine whether these perception and attitudes differ by doctors' characteristics, such as sex, position, and specialties, and (3) to understand the relationship between overall perception of patient safety in their working unit and each sub domain of patient safety culture. A survey was conducted with 135 doctors working in a university hospital in Korea. After descriptive analyses and chi-square tests of subgroup differences, a multivariate-regression of overall perception of patient safety in their unit with sub-domains of patient safety culture was conducted. Overall, a significant proportion of doctors expressed negative perception of their working units' patient safety culture, many reporting potentials for patient safety problems to occur in their unit. They also negatively viewed their hospital leadership's commitment on patient safety. Regarding the patient safety in their working unit, doctors were most worried about staffing level and observance of safety procedures. Most doctors did not know how and which medical error to report. They also perceived that medical errors would work against them personally and penalize them. About 22 percent of respondents believed that even seriously harmful medical errors were not reported.

• Journal of Microbiology
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• v.44 no.4
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• pp.447-452
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• 2006

The murine ecotropic retroviral receptor has been demonstrated to function as a mouse cationic amino acid transporter 1(mCAT1), and is comprised of multiple membranespanning domains. Feral mouse (Mus dunni) cells are not susceptible to infection by the ecotropic Moloney murine leukemia virus (MoMLV), although they can be infected by other ecotropic murine leukemia viruses, including Friend MLV and Rauscher MLV. The relative inability of MoMLV to replicate in M. dunni cells has been attributed to two amino acids $(V_{214}\;and\;G_{236})$ located within the third extracellular loop of the M. dunni CAT1 receptor (dCAT1). Via the exchange of the third extracellular loop of the mCAT1 cDNA encoding receptor from the permissive mouse and the corresponding portion of cDNA encoding for the nonpermissive M. dunni receptor, we have identified the most critical amino acid residue, which is a glycine located at position 236 within the third extracellular loop of dCAT1. We also attempted to determine the role of the third extracellular loop of the M. dunni CAT1 receptor with regard to the formation of the syncytium. The relationship between dCAT1 and virus-induced syncytia was suggested initially by our previous identification of two MLV isolates (S82F in Moloney and S84A in Friend MLV), both of which are uniquely cytopathic in M. dunni cells. In an attempt to determine the relationship existing between dCAT1 and the virally-induced syncytia, we infected 293-dCAT1 or chimeric dCAT1 cells with the S82F pseudotype virus. The S82F pseudotype virus did not induce the formation of syncytia, but did show increased susceptibility to 293 cells expressing dCATl. The results of our study indicate that S82F-induced syncytium formation may be the result of cell-cell fusion, but not virus-cell fusion.

• Polymer(Korea)
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• v.26 no.1
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• pp.37-44
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• 2002

The polymer blends of waste polyvinyl chloride (RPVC) and waste polyethylene(RPE) were prepared by melt mixing, and their morphology and tensile properties were evaluated after the copolymers having an ethylene group in backbone and ester group in side position were added as comptatibilizers. The blend compositions were varied as follows ; RPVC/RPE 85/15 wt%, where RPVC formed a continuous phase : 50/50, mid composition : 15/85, RPE a continuous phase. The blends revealed a very low compatibility between component polymers because they showed domain sizes greater than $10\mu\textrm{m}$ over all compositions, especially the worst compatibility around mid composition. The blends showed higher compatibility when ethylene vinylacetate copolymer(EVA) and ethylene ethylacrylate-graft-methyl methacrylate copolymers(EEA-MMA) were added.

• The Korean Journal of Rehabilitation Nursing
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• v.8 no.2
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• pp.119-128
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• 2005

Purpose: The purpose of this study was to analyze research in the Korean Journal of Rehabilitation Nursing and to suggest further perspective for rehabilitation nursing research. Method: In this study we reviewed the contents of 134 articles published in this journal from its beginning year 1998 to 2004. Results: The majority of subjects were adult patients. The type of disease were Cerebrovascular Accident, Neuromuscular disease, Cancer patients, Urogenital disease such as Chronic Renal Failure, Spinal cord injury. Domain of research almost was client, type of research were survey(34.3%), quasi experimental study(20.9%), correlation study(19.4%). Nursing intervention of experimental study was exercise(39.0%), education(17.1%). Place of data collection was hospital (58.2%), position of researcher was professor(67.2%), method of data collection was questionnaire(50.7%). Conclusion: There has been a lack of written consent, child rehabilitation, measurement tool development, qualitative research. More studies about rehabilitation nursing are needed to extend the role and fields for professional nursing.

• Journal of Navigation and Port Research
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• v.42 no.2
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• pp.127-136
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• 2018

The motion response of floating structures is of significant concern in marine engineering. Floating structures can be disturbed by waves, winds, and currents that create undesirable motions of the vessel, therefore causing challenges to its operation. For a floating structure, mooring lines are provided in order to maintain its position; these should also produce a restoring force when the vessel is displaced. Therefore, it is important to investigate the tension of mooring lines and the motion responses of a twin barge when moored to guarantee the safety of the barge during its operation. It is essential to precisely identify the characteristics of the motion responses of a moored barge under different loading conditions. In this study, the motion responses of a moored twin barge were measured in regular waves of seven different wave directions. The experiment was performed with regular waves with different wavelengths and wave directions in order to estimate the twin-barge motions and the tension of the mooring line. In addition, the motion components of roll, pitch, and heave are completely free. In contrast, the surge, sway, and yaw components are fixed. In the succeeding step, a time-domain analysis is carried out in order to obtain the responses of the structure when moored. As a result, the Response Amplitude Operator (RAO) motion value was estimated for different wave directions. The results of the experiment show that the motion components of the twin barge have a significant effect on the tension of the mooring lines.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.22 no.4
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• pp.335-341
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• 2009

In this paper, review of developed MLS-based finite elements and a proposal for their applications are described. The shape functions and their derivatives of MLS-based finite elements are constructed using Moving-Least Square approximation. In MLS-based finite element, using the adequate influence domain of weight function used in MLS approximation, kronecker delta condition could be satisfied at the element boundary. Moreover, because of the characteristics of MLS approximation, we could easily add extra nodes at an arbitrary position in MLS-based finite elements. For these reasons, until now, several variable-node elements(2D variable element for linear case and quadratic case and 3D variable-node elements) and finite crack elements are developed using MLS-based finite elements concept. MLS-based finite elements could be extended to 2D variable-node triangle element, 2D finite crack triangle element, variable-node shell element, finite crack shell element, and 3D polyhedron element. In this paper, we showed the feasibility of 3D polyhedron element at the case of femur meshing.

• Wind and Structures
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• v.30 no.4
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• pp.367-378
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• 2020

Two-dimensional Delayed Detached Eddy Simulation (DDES) was carried out to investigate the uniform flow over a twin-box bridge deck (TBBD) with various gap ratios of L/C=5.1%, 12.8%, 25.6%, 38.5%, 73.3% and 108.2% (L: the gap-width between two girders, C: the chord length of a single girder) at Reynolds number, Re=4×104. The aerodynamic coefficients of the prototype deck with gap ratio of 73.3% obtained from the present simulation were compared with the previous experimental and numerical data for different attack angles to validate the present numerical method. Particular attention is devoted to the fluctuating pressure distribution and forces, shear layer reattachment position, wake velocity and flow pattern in order to understand the effects of gap ratio on dynamic flow interaction with the twin-box bridge deck. The flow structure is sensitive to the gap, thus a change in L/C thus leads to single-side shedding regime at L/C≤25.6%, and co-shedding regime at L/C≥35.8% distinguished by drastic changes in flow structure and vortex shedding. The gap-ratio-dependent Strouhal number gradually increases from 0.12 to 0.27, though the domain frequencies of vortices shedding from two girders are identical. The mean and fluctuating pressure distributions is significantly influenced by the flow pattern, and thus the fluctuating lift force on two girders increases or decreases with increasing of L/C in the single-side shedding and co-shedding regime, respectively. In addition, the flow mechanisms for the variation in aerodynamic performance with respect to gap ratios are discussed in detail.