• The Korean Journal of Pharmacology
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• v.22 no.1 s.38
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• pp.60-70
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• 1986

Distributions of serum dopamine-${\beta}$-hydroxylase(DBH) activity and thermostability in a randomly selected population of Korean adults were studied to investigate the genetic factor which could exert an influence on the serum DBH activity and thermostability. The results were followings: 1. The mean serum DBH activity in a randomly selected population of adults was $18.3{\pm}4.5$ umol/min/l($mean{\pm}SD;n=327$) which showed no age or sex variation. 2. The frequency distribution showed no isolated subgroup with very low serum DBH activity. 3. When the ratio of enzyme activity after heating $55^{\circ}C$ for 20 minutes to that before heating (heated-to-control or H/C ratio). was used as a measure of thermostability, the mean serum DBH H/C ratio in a randomly selecfld population, of adults was $0.90{\pm}0.17(mean{\pm}SD; n=327)$ which showed no age or sex variation. 4. Serum DBH H/C ratio showed unimodal, homogeneous distribution. 5. There was significant negative correlation between serum DBH activity and H/C ratio(r=-0.39. p<0.01). 6. Subjects with H/C ratio less than 0.1 had significantly higher basal enzyme activity $(22.2{\pm}4.5)$ $(mean{\pm}SD;n=33)$ umo1/min/1 than those with H/C ratio more than 1.09 $(15.5{\pm}3.3)$ $(mean{\pm}SD;n=32)$ umo1/min/1. This study shows that the distribution patterns of serum DBH activity and thermostability of Korean population are considerably different from those of Caucasian and it might be a line of evidence for the different inheritance pattern of plasma DBH enzyme between these racial groups.

• Journal of the Korean Geographical Society
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• v.43 no.3
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• pp.337-357
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• 2008

This study examines the characteristics of population ageing and the employment of aged workers in Seoul. Population indexes such as aged/child ratio and longevity degree are analyzed to identify the time-spatial changes and differentiation of population ageing by Gu. Job offerers, job seekers and employees related to the aged workers are also analyzed using data from Center of Job Placement for the Aged in Seoul. The results indicate that population ageing of Seoul has progressed faster than other regions in recent years. In addition, regional differences in tendency of population ageing is obvious even within Seoul. The percentage of unskilled laborer is much higher in Seoul compared with other regions. There is geographical differentiation in employment of aged workers among regions within Seoul. The employment opportunity of the aged is high in core economic areas of Seoul, while low in the outer residential area. This shows geographical mismatch between job offerers and seekers, which means that it is difficult for aged workers to get the jobs near to their residence. Accordingly, governmental support and intervention is needed considering their lower mobility.

• Journal of the Korean Statistical Society
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• v.35 no.4
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• pp.377-395
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• 2006

In this paper we have suggested a family of chain estimators of the population mean $\bar{Y}$ of a study variate y using two auxiliary variates in two phase (double) sampling assuming that the coefficient of variation of the second auxiliary variable is known. It is well known that chain estimators are traditionally formulated when the population mean $\bar{X}_1$ of one of the two auxiliary variables, say $x_1$, is not known but the population mean $\bar{X}_2$ of the other auxiliary variate $x_2$ is available and $x_1$ has higher degree of positive correlation with the study variate y than $x_2$ has with y, $x_2$ being closely related to $x_1$. Here the classes are constructed when the population mean $\bar{X}_1\;of\;X_1$ is not known and the coefficient of variation $C_{x2}\;of\;X_2$ is known instead of population mean $\bar{X}_2$. Asymptotic expressions for the bias and mean square error (MSE) of the suggested family have been obtained. An asymptotic optimum estimator (AOE) is also identified with its MSE formula. The optimum sample sizes of the preliminary and final samples have been derived under a linear cost function. An empirical study has been carried out to show the superiority of the constructed estimator over others.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.9
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• pp.1369-1377
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• 2020

Objective: The main objectives of the present study were to assess the genetic diversity, population structure and to appraise the efficiency of ongoing selective breeding program in the closed nucleus herd of Nellore sheep through pedigree analysis. Methods: Information utilized in the study was collected from the pedigree records of Livestock Research Station, Palamaner during the period from 1989 to 2016. Genealogical parameters like generation interval, pedigree completeness, inbreeding level, average relatedness among the animals and genetic conservation index were estimated based on gene origin probabilities. Lambs born during 2012 and 2016 were considered as reference population. Two animal models either with the use of F_i or ΔF_i as linear co-variables were evaluated to know the effects of inbreeding on the growth traits of Nellore sheep. Results: Average generation interval and realized effective population size for the reference cohort were estimated as 3.38±0.10 and 91.56±1.58, respectively and the average inbreeding coefficient for reference population was 3.32%. Similarly, the effective number of founders, ancestors and founder genome equivalent of the reference population were observed as 47, 37, and 22.48, respectively. Fifty per cent of the genetic variability was explained by 14 influential ancestors in the reference cohort. The ratio f_e/f_a obtained in the study was 1.21, which is an indicator of bottlenecks in the population. The number of equivalent generations obtained in the study was 4.23 and this estimate suggested the fair depth of the pedigree. Conclusion: Study suggested that the population had decent levels of genetic diversity and a non-significant influence of inbreeding coefficient on growth traits of Nellore lambs. However, small portion of genetic diversity was lost due to a disproportionate contribution of founders and bottlenecks. Hence, breeding strategies which improve the genetic gain, widens the selection process and with optimum levels of inbreeding are recommended for the herd.

• Journal of Korean Medical Science
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• v.33 no.47
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• pp.302.1-303.10
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• 2018

Background: A considerable amount of research has shown that knowledge and appropriate awareness are essential for encouraging positive behaviors and promoting health. In Korea, the roles that behavioral changes play in the prevention of cancer have been an important issue since the introduction of the 10 codes for cancer prevention in 2006. Thus, the present study investigated the associations of tobacco-related knowledge with awareness and attitudes towards positive smoking-cessation behaviors. Methods: The present study analyzed data from the 2010 national questionnaire survey (n = 1,006). This study evaluated sociodemographic characteristics, smoking status, self-rated health status, health-related interests, and the accuracy of 12 tobacco-related statements to determine knowledge level and to investigate its impact on awareness and behaviors related to smoking. These parameters were examined and staged using the Precaution Adoption Process Model. Results: A higher level of tobacco-related knowledge was significantly associated with a positive attitude towards smoking cessation (5-8 correct answers: odds ratio [OR], 2.53; 95% confidence interval [CI], 1.57-4.08; ${\geq}9$ correct answers: OR, 3.90; 95% CI, 2.22-6.82; reference: ${\leq}4$ correct answers). Interestingly, among current smokers, only those who correctly responded to ${\geq}9$ of 12 tobacco-related statements were significantly associated with a positive attitude towards smoking cessation. Conclusion: This study found that having a higher level of tobacco-related knowledge had a significant impact on positive attitudes towards smoking cessation. This suggests that there is a need to disseminate appropriate knowledge to the general population to encourage positive attitudes and promote healthful behaviors in terms of smoking.

• Journal of applied mathematics & informatics
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• v.23 no.1_2
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• pp.385-395
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• 2007

The dynamics of a prey-predator system, where predator population has two stages, juvenile and adult with harvesting are modelled by a system of delay differential equation. Our analysis shows that, both the delay and harvesting effort may play a significant role on the stability of the system. Numerical simulations are given to illustrate the results.

• Structural Engineering and Mechanics
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• v.60 no.6
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• pp.953-977
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• 2016

Modern performance-based design methods require ways to determine the factual behavior of structures subjected to earthquakes. Drift ratio demands are important measures of structural and/or nonstructural damage of the structures in performance-based design. In this study, global drift ratio and interstory drift ratio demands, obtained by nonlinear time history analysis of three generic RC frames using code-compatible ground motion record sets, are statistically evaluated. Several ground motion record sets compatible with elastic design spectra defined for the local soil classes in Turkish Earthquake Code are used for the analyses. Variation of the drift ratio demands obtained from ground motion records in the sets and difference between the mean of drift ratio demands calculated for ground motion sets are evaluated. The results of the study indicate that i) variation of maximum drift ratio demands in the sets were high; ii) different drift ratio demands are calculated using different ground motion record sets although they are compatible with the same design spectra; iii) the effect of variability due to random causes on the total variability of drift ratio demands is much larger than the effect of variability due to differences between the mean of ground motion record sets; iv) global and interstory drift ratio demands obtained for different ground motion record sets can be accepted as simply random samples of the same population at %95 confidence level. The results are valid for all the generic frames and local soil classes considered in this study.

• Korean System Dynamics Review
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• v.4 no.2
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• pp.71-94
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• 2003

The purpose of this dissertation is to build a development density control model and estimate optimum developmental density level for a sustainable urban growth management. To develop the model, system dynamics modeling approach was used. The model was developed to analyze how urban growth, transition, and decay occur depending on the interaction among population, houses, industry structure, land and urban infrastructure such as road, water supply, and sewage treatment facilities. The model was applied to Anyang city to estimate optimum density level. Extensive computer simulation was conducted to find out the maximum numbers of population, industry structure, houses, and cars that can be adequately sustained with the current Anyang city's infrastructure capacity. The computer simulation result shows that the city is overpopulated by some 90,000 people. It nab analyzed that 20％ increase of existing capacity of urban infrastructure is necessary to support current population of Anyang city. To reduce the population to the adequate level whereby the current urban infrastructure can sustain, the current city regulation on floor area ratio needs be strengthened at least 20％ to 35%.

• Korean journal of applied entomology
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• v.37 no.2
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• pp.207-212
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• 1998

Tea field-collected populations of the tea red spider mite (Tetranychus kazawai Kishida) from five different locations in the southern region of Korea were assessed for resistance to seven acaricides using leaf spray method. There were considerable differences in susceptibility depending on the tested acaricides and the location from which the population was collected. The populations showing high resistance ratio of more than 20 with respect to certain acaricide were as follows: the Sungjun and Cheju populations to azocyclotin, tebufenpyrad, fenpyroximate, pyridaben, propargite, and fenpropathrin; the Haenam population to propargite and fenpyroximate; the Bosung population to propargite; the Youngam population to pyridaben. Therefore, the use of other alternative acaricides against the Sungjun and Cheju populations is needed. However, careful selection of the appropriate acaricide against the Haenam, Bosung and Youngam populations of the tea red spider mite might be maintained in effective control.

• The Mathematical Education
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• v.57 no.4
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• pp.413-431
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• 2018

In this study, I developed an activity oriented lesson to support the understanding of probabilistic and quantitative estimating population ratios according to the standard statistical principles and discussed its implications in didactical respects. The developed activity lesson, as an efficient physical simulation activity by sampling with replacement, simulates unknown populations and real problem situations through completely closed 'Closed Box' in which we can not see nor take out the inside balls, and provides teaching and learning devices which highlight the representativeness of sample ratios and the sampling variability. I applied this activity lesson to the gifted students who did not learn estimating population ratios and collected the research data such as the activity sheets and recording and transcribing data of students' presenting, and analyzed them by Qualitative Content Analysis. As a result of an application, this activity lesson was effective in recognizing and reflecting on the representativeness of sample ratios and recognizing the random sampling variability. On the other hand, in order to show the sampling variability clearer, I discussed appropriately increasing the total number of the inside balls put in 'Closed Box' and the active involvement of the teachers to make students pay attention to controlling possible selection bias in sampling processes.