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Studies on the Nonvolatile Organic Acids in Kimchis fermented at Different Temperatures (숙성온도(熟成溫度)에 따른 김치의 비휘발성(非揮發性) 유기산(有機酸)에 관(關)한 연구(硏究))

  • Kim, Hyun-Ock;Rhee, Hei-Soo
    • Korean Journal of Food Science and Technology
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    • v.7 no.2
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    • pp.74-81
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    • 1975
  • Nonvolatile organic acids were determined in raw Chinese cabbage, Kimchis fermented at $6^{\circ}{\sim}7^{\circ}C$ and at $22^{\circ}{\sim}23^{\circ}C$. Total acids were isolated by ion-exchange chromatography and quantitative determination of individual acids was performed by silicic acid partition column chromatography. Acids were identified qualitatively by paper chromatography. Palatability of Kimchis was evaluated by nine pannels. Results were as follows: Maleic, fumaric, lactic, succinic, malonic, oxalic, glycolic, malic, citric, tartaric, sulphuric and phosphoric acid were found in raw Chinese cabbage. Kimchis fermented at $6^{\circ}{\sim}7^{\circ}C$, and at $22^{\circ}{\sim}23^{\circ}C$. In raw Chinese cabbage, most of organic acids were in salt form and malic acid was highest in amount. In Kimchi fermented at $6^{\circ}{\sim}7^{\circ}C$, the amount of lactic acid and succinic acid was higher than that in Kimchi fermented at $22^{\circ}{\sim}23^{\circ}C$, and, tartaric, oxalic, malic, malonic, maleic, glycolic and fumaric acids were less than those in Kimchi fermented at $22^{\circ}{\sim}23^{\circ}C$. Kimchi fermented at $6^{\circ}{\sim}7^{\circ}C$ had a more flavorous sour taste than Kimchi fermented at $22^{\circ}{\sim}23^{\circ}C$. It is assumed that large amount of lactic acid and succinic acid in Kimchi fermented st $6^{\circ}{\sim}7^{\circ}C$ have a connection with flavorous sour taste.

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The Abnormality of Posterior Default Mode Network in Medication-Naïve Attention-Deficit Hyperactivity Disorder Children : Resting State fMRI Study (약물 복용력이 없는 주의력결핍 과잉행동장애 아동에서의 뒤쪽 내정상태회로 이상 : 휴식상태 기능적 뇌자기공명영상 연구)

  • Choi, Jee-Wook;Go, Hyo-Jin;Woo, Young-Sup;Song, Seung-Hoon;Yang, Po-Song;Jeong, Bum-Seok
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.23 no.2
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    • pp.57-62
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    • 2012
  • Objectives : Characteristic symptoms, including hyperactivity and easy distractibility, in children with attention-deficit hyperactivity disorder (ADHD) suggest that their brain status, even at rest, might differ from that of healthy children. This study was conducted in order to determine whether resting state brain activity is compromised in medication-naive children with ADHD. Methods : Twenty medication-naive children with ADHD (mean age $10.3{\pm}2.5$) and 28 age- and gender-matched healthy volunteers (mean age $10.3{\pm}2.0$) underwent measurements for resting state brain activity using functional magnetic resonance imaging (fMRI). Among resting state related-independent components (RSICs) extracted from fMRI data using independent component analysis, a significant difference in RSICs was observed between groups, using a mixed Gaussian/gamma model. Results : Except for IQ, which was higher in the healthy control group, no demographic difference was observed between the two groups (p<.001). Significantly less activation of one RSIC, which includes the bilateral precuneus/posterior cingulate cortex, occipito-temporal junction, and anterior cingulate cortex, was observed in the ADHD group, compared with the control group (p<.05). Conclusion : An abnormal RSIC, posterior default mode network (DMN), was observed in the medication-naive ADHD group. Results of our study suggest that abnormality of posterior DMN is one of the main pathophysiologies of ADHD.

Fabrication and characterization of GaN substrate by HVPE (HVPE법으로 성장시킨 GaN substrate 제작과 특성 평가)

  • Oh, Dong-Keun;Choi, Bong-Geun;Bang, Sin-Young;Eun, Jong-Won;Chung, Jun-Ho;Lee, Seong-Kuk;Chung, Jin-Hyun;Shim, Kwang-Bo
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.20 no.4
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    • pp.164-167
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    • 2010
  • Bulk GaN single crystal with 1.5 mm thickness was successfully grown by hydride vapor phase epitaxy (HVPE) technique. Free-standing GaN substrates of $10{\times}10,\;15{\times}15$ mm size were fabricate after lift-off of sapphire substrate and their optical properties were characterized properties for device applications. X-ray diffraction patterns showed (002) and (004) peak, and the FWHM of the X-ray rocking curve (XRC) measurement in (002) was 98 arcsec. A sharp photoluminescence spectrum at 363 nm was observed and defect spectrum at visible range was not detected. The hexagonal-shaped etch-pits are formed on the GaN surface in $200^{\circ}C\;H_3PO_4$ at 5 minutes. The defect density calculated from observed etch-pits on surface was around $5{\times}10^6/cm^2$. This indicates that the fabricated GaN substrates can be used for applications in the field of optodevice, and high power electronics.

A Clinical Case Study of Common Peroneal Nerve Palsy(Foot Drop) Following Entrapment Neuropathy (압박성 신경병증에 의한 족하수(足下垂) 환자(患者) 1례(例)에 대한 임상적(臨床的) 고찰(考察))

  • Shin, Jeong-Cheol;Lee, Dong-Hyun;Wei, Tung-Shuen;Kim, Seon-Jong;Choe, Won-Hwak;Ryu, Chung-Ryul;Yun, Yeo-Choong;Cho, Myung-Rae;Che, Wu-Suk;Na, Gun-Ho
    • Journal of Acupuncture Research
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    • v.22 no.4
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    • pp.1-12
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    • 2005
  • Objectives : The Purpose of this study is to report in patient with common peroneal nerve palsy, who improved by oriental medical treatament. Methods : We Checked the temperature of a leg by Digital Infrared Thermal Imaging(DITI) at intervals of 10 days, angle of active dorsiflexion and range of active motion for estimating the improvement of symptoms. We used the Visual Analogue Scale(VAS) for estimating the degree of pain, too. Results : After 4 weeks treatment, the movement and power of ankle joint improved to nearly normal range. The degree of active dorsiflexion of the ankle increased from $-40^{\circ}\;to\;15^{\circ}$ and range of active motion increased from Gr III to Gr I. The difference of temperature between the both legs decreased remarkably. Conclusion : In this case we experienced improvement of symptoms by conservative oriental medical therapy, e.g acupuncture stimulation, herbal medication, physical therapy. It should be needed further investigation on common peroneal nerve palsy and its symptoms in order to set up a reasonable standard about a surgical operation.

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A Clinical study for cervical headache (경추성(頸椎性) 두통(頭痛)에 대한 임상적(臨床的) 연구(硏究))

  • Cho Eun-Hee;Hwang Yoo-Jin;Lyu Dong-Soo;Yoon Min-Young;Kim Hyun-Jung;Jin Sin-Young;Cho Nam-Geun;Lee Byeung-Cheul;Lee In;Lee Geon-Mok
    • Journal of Acupuncture Research
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    • v.18 no.6
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    • pp.114-124
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    • 2001
  • Objective : To evaluate the effect of treatment for cervical headache by using Cathami Flos herbal acupuncture that are known for anti-inflammatory and function of relieving the pain. Methods : Evaluated the result of Cathami Flos herbal acupuncture treatment twice in a week for patients who have cervical headache with cervical MRI abnormality at Gun-Po Oriental medical hospital in affiliation with wonkwang university. Results : 1. In the distribution of sex; Female rate was 45.9% and male rate was 54.1%., In the distribution of age, Thirties and forties group was the largest group by each 32.8%. 2. In the distribution of Cervical MRI abnormality; Abnormality of C2/3, C3/4, C4/5 was 94.6%, disk bulging and disk protrusion was 94.5%. 3. The effect of treatment by age was as follows; Thirties and forties group were each 31.1%, total 62.2%. 4. In the distribution of treatment period and curative value; 'Two weeks to four week' was 63.9%. Conclusion : These results shows that it is possible for headache to be occurred by cervical abnormality and that the effect of treatment by Cathami Flos herbal acupuncture is exellent by relaxing contracted muscles, strengthening weakened' ligaments and improving inflammatory parts.

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Production of Keratinolytic Protease by Bacillus pumilus RS7 and Feather Hydrolysate As a Source of Amino Acids (Bacillus pumilus RS7에 의한 난분해성 케라틴 분해효소의 생산 및 아미노산 공급원으로서 우모 분해산물)

  • Woo, Eun-Ok;Kim, Min-Ju;Son, Hyeng-Sik;Ryu, Eun-Youn;Jeong, Seong-Yun;Son, Hong-Joo;Lee, Sang-Joon;Park, Geun-Tae
    • Journal of Environmental Science International
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    • v.16 no.10
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    • pp.1203-1208
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    • 2007
  • Feathers are produced in huge quantities as a waste product at commercial poultry processing plants. Since feathers are almost pure keratin protein, feather wastes represent an alternative to more expensive dietary ingredients for animal feedstuffs. Generally they become feather meal used as animal feed after undergoing physical and chemical treatments. These processes require significant energy and also cause environmental pollutions. Therefore, biodegradation of feather by microorganisms represents an alternative method to prevent environment contamination. The aim of this study was to investigate cultural conditions affecting keratinolytic protease production by Bacillus pumilus RS7. We also assessed the nutritive value of microbial and alkaline feather hydrolysates, The composition of optimal medium for the keratinolytic protease was fructose 0.05%, yeast extract 0.3%, NaCl 0.05%, K2HPO4 0.03%, KH2PO4 0.04% and MgCl2 6H2O 0.01%, respectively. The optimal temperature and initial pH was $30^{\circ}C$ and 9.0, respectively. The keratinolytic protease production under optimal condition reached a maximum after 18 h of cultivation. Total amino acid content of feather hydrolysates treated by NaOH and B. pumilius RS7 was $113.8\;{\mu}g/ml$ and $504.9\;{\mu}g/ml$, respectively. Essential amino acid content of feather hydrolysates treated by NaOH and B. pumilius RS7 was $47.2\;{\mu}g/ml$ and $334.0\;{\mu}g/ml$, respectively. Thus, feather hydrolysates have the potential for utilization as an ingredient in animal feed.

Break Point Chlorination (BPC) Characteristics for Heavy Metals Removal in Plating Wastewater Treatment (염소산화공정을 이용한 도금폐수의 중금속 제거 특성)

  • Jung, Byung-Gil;Lee, Seung-Won;Yun, Kwon-Gam;Jung, Jin-Hee;Kim, Jeong-Woong;Choi, Young-Ik
    • Journal of Environmental Science International
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    • v.29 no.11
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    • pp.1055-1064
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    • 2020
  • In this research, heavy metals and T-P removal characteristics of plated wastewater are derived using BPC(Break Point Chlorination) process. AA sedimentation pond outflow(Influence) was evaluated for the removal efficiency of heavy metal(Ni) and T-P at a reaction time of 25 minutes by NaOCl input volume(9, 11, 13 and 15 mL). In the case, the higher the NaOCl input volumes, the higher the ORP values were maintained and the higher the removal efficiency tended to be. On the other hand, T-P was judged to have a low relationship between the ORP value and the removal efficiency. In addition, the efficiency of removal heavy metals and T-P in the plated wastewater by injecting 10 mL, 15 mL, 20 mL and 25 mL NaOCl, increased as the amount of NaOCl injected increased, the amount of NaOH input for pH increased. It was found that suspended solid in effluence also increased. It was also observed that the color of the plating wastewater changed from yellowish green to green to charcoal gray to black as the amount of NaOCl injected increased. Treatment characteristics of the reaction time, the longer the reaction time with the substance to be treated after the input of NaOCl, the more the heavy metal removal efficiency tended to increase. Through XRF analysis of the sludge, the constituents in the sludge such as NaCNO, CNCl, Na3PO4, CrO4, 2Na2CrO4 and 2NaNO3 will be analyzed in detail, and the mechanisms of the reaction between the plated wastewater and the complex compound will be elucidated.

A Study on Nurse - Patient Interacting Behaviour Patterns (간호사-환자 상호작용 양상에 관한 연구)

  • 이성심;지성애
    • Journal of Korean Academy of Nursing
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    • v.20 no.1
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    • pp.61-78
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    • 1990
  • The purpose of the present study is to confirm the interacting behavior between nurses and patients and other things concerned herewith. Subjects of investigation were : 42 nurses selected out of the average nurses who serve in hospital as nurses assigned to medical and surgical wards : and 42 male and female adult patients selected out of the average patients who were under the care of the nurse individuals and can make themselves understood verbally. A nurse and her patient were paired off for questioning. Materials for statistics were gathered by means of observaing interactions- - verbal and nonverbal - -of the chosen subjects for four hours every day from 7 : 30 a.m. through 7 : 30 p.m. between on July 15, 1988 and on Aug. 16, 1988. Classified by patterns, the materials observed and gathered were preliminarily analyzed by this researcher, and then reexamined in a full-fledged way by one professor, three nurses and three non - nurses. The researcher depended chiefly on Frequency, ANOVA, Pearson's Correlation Coefficient attached to SPSS Computer System for the process of gathered materials. The results of this investigations are follows 1) A total of 98 times' interactions between nurses and patients were provided during observation of 168 hours. 2) It took them the averaged 264.8 seconds(around 4.4 minutes) per a couple of subjects to interact between nurses and patients during observation of four hours. 3) The aim of interactions between nurses and patients appear that 29 times of injection amounted to 29.6% the most, 27 times of PO around to 27.6% the next most, 25 times of vital check to 25.5% the next most, 17 times of independent nursing works and round to 17.3% the least most. 4) As a result of qualitative analyzing the interactions between nurses and patients by the distinctive method of words were positively recognized in 19 cases with 45.2% and negatively in 23 cases with 54.8%. 5) A total of 2, 193 times. interaction behaviours between nurses and patients were provided. The frequency of these interaction behaviours took place l, 364 times with 62.2% to nurse, and 829 times with 37.8% to patients. 6) The classification of verbal and nonverbal interaction behaviour between nurses and patients indicated that it is amounted to 64.9% for verbal behaviour numbered 1, 423 and 35.1% for nonverbal one numbered 770. 7) The frequency of verbal behaviour between nurses and patients numbered 1, 423 in total. They took place 924 times to nurses and 499 times to patients, it can be also amounted to 64.9% and 35.1% respectively in percentagewise. 8) In interactions between nurses and patients, it turned out that the frequency of nurses' turns, which the present research discovered averaged 16.8 times for four hours, and the verbal behaviours by numbered 9.7 on an average. 9) Nonverbal behaviours between nurses and patients numbered 770 in total, it is assigned 440 times to nurse with 57.1% and 330 times to patients with 42.9%. 10) The investigation releases in formation that the frequency of verbal behaviours between nurses and patients was very much concerned with the age of patients(r=0.422, p<.01) and the number of patients one nurse has under her care(r=-0.356, p<.01). 11) It was found that were deep relationship of the number of a nurses turn with the patients age(r=0.377, p<.01) and the nurses burden of caring patients(r=-0.372, p<.01).

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The Effect of the Transforming Growth $Factor-{\beta}$ on Collagen Synthetic Activity of the Human Periodontal Ligament Cells and Human Gingival Fibroblasts (치주인대세포와 치은섬유아세포의 단백질과 교원질 합성능에 대한 Transforming Growth $Factor-{\beta}$의 효과)

  • Kim, Mi-Jeong;Lee, Jae-Mok;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.26 no.2
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    • pp.429-447
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    • 1996
  • Transforming growth factor $-{\beta}$ is one of the polypeptide growth factors that mediate the activity of mesenchymal cells and regulate wound healing process via cell proliferation, migration and extracellular matrix formation. The purposes of this study is to evaluate the effects of transforming growth factor $-{\beta}$ on the protein synthetic activity of human periodontal ligament cells and human gingival fibroblasts. The cells which were prepared were primary cultured gingival fibroblasts and periodontal ligament cells from humans, and the fourth or sixth subpassage were used in the experiments. Cells were seeded and at a confluent state, 0, 0.5, I, 2.5, 5, 10 ng/ml $TGF-{\beta}$ and $2{\mu]Ci/ml\;[^3H]$ proline were added to the cells and cultured for 24 hours. Then, 1 and 5 ng/ml concentrations were selected and added to confluent cells and cultured for 24 and 48 hours. They were labeled with $2{\mu}Ci/ml\;[^3H]$ proline for 24 hours and a collagen assay was done by the Peterkofsky and Diegelman method. The results were presented as the mean disintegration per minute (dpm) per well and S.D. of four determinations, The results were as follows. : The total protein, collagen and noncollagenous protein synthesis in periodontal ligament cells and gingival fibroblasts were increased dose- dependently by transforming growth factor-p to 2.5-5 ng/ml concentration and decreased at 10 ng/ml concentration. The percent of collagen was slightly changed according to the concentration of transforming growth factor-po The effect of transforming growth $factor-{\beta}$ was not specific for collagen synthesis since it increased the total, noncollagenous and collagenous protein, simultaneously. In the comparison of protein synthetic activity between the human periodontal ligament cells and human gingival fibroblasts, the human gingival fibroblasts had higher activities than the human periodontal ligament cells at all times and concentrations of $TGF-{\beta}$. In the comparison of protein synthetic activity between the 24 hour effect and the 48 hour effect of $TGF-{\beta}$, the 48 hour cultured cells' synthetic activity decreased more than the 24 hour cultured cells at human periodontal ligament cells and human gingival fibroblasts. In conclusion, $TGF-{\beta}$ has important roles in the stimulation of protein synthesis in human periodontal ligament cells and human gingival fibroblasts. Thus, it may be useful for clinical application in periodontal regenerative procedures.

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Garlic flavor (마늘 flavor)

  • Kim, Mee Ree;Ahn, Seung Yo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.12 no.2
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    • pp.176-187
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    • 1983
  • Volatile flavor components of garlic and factors which influence on its flavors were reviewed. Growth, storage and processing conditions influence on the flavor intensity of garlic. To intensify garlic flavors, it is desirable that sufficient sulfate nutrition be supplied to the soil of growing garlic and that the suggested proportions of mineral composition and water content be considered. And to maintain the flavor intensity of post harvested garlic, flavor losses taken place during over inter storage mainly due to respiration, sprout and decay, have to be minimized. Among the various storage methods, combination method of post harvest hot-air drying and low temperature ($0^{\circ}C$), low humidity (RH 70-75%) is useful. The flavor of processed garlic is very much decreased as compared with that of fresh, and the decreasing rate of flavors depends on processing method. The synthetic garlic flavors were obtained by three types based on intermediate thiosulfinate, S-alk(en) yl-$\small{L}$-cyteine sulfoxlde-alliinase fission products and $\small{L}$-5-alk (en)yl thiomethylhydantoin ${\pm}$ S-oxides. These synthetic garlic flavors may be promised to be applied to food additives.

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