• Composites Research
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• 제27권2호
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• pp.47-51
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• 2014

본 논문은 기존의 유/공압 및 전기식 모터를 대체할 수 있는 경량, 고성능 지능소자 구동기를 설계/제작하고 이를 소형 무인비행체의 조종익 시스템에 적용 가능성을 연구한 것이다. 또한 압전 복합재료 작동기에 대한 성능평가를 수행하였으며, 유니모프 및 바이모프 형태의 작동기를 제작하여 각각의 작동 특성을 확인하였다. 이와 같은 성능시험 평과 결과를 통해 바이모프 형태의 작동기가 하중 유무와 무관하게 선형적인 받음각 변화를 가짐을 알 수 있었다. 이러한 지능소자 구동 시스템은 소형 로봇, 유도무기 및 MAV, UAV의 조종익 제어 시스템으로 사용될 수 있는 가능성을 확인하였다.

• 한국추진공학회지
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• 제14권6호
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• pp.89-102
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• 2010

본 논문에서는 항공우주분야의 구동장치와 여러 산업분야에서 응용되고 있는 미래 지향적 구동기의 기술에 대한 사항과 발전방향에 대해 연구하였다. 특히, 항공기 비행조종면 구동장치의 경우 기존에는 기계식 링키지나 무게 대비 출력이 높은 유 공압 구동기가 많이 사용되었으나 최근에는 대부분의 항공기에서 사용 중인 Fly-By-Wire 시스템과 더 나아가 'More Electric', 'All Electric' 시스템으로의 변화가 이루어지고 있다. 전기식 유압구동기와 전기식 구동장치의 경우 효율이나 안전성 그리고 비용적인 측면에서 우수하기 때문에 근래에 지속적인 개발이 진행되고 있다. 또한, 최근에는 구동기의 무게와 정밀도 그리고 응답속도의 향상을 위해 신소재를 이용한 새로운 분야의 구동기들이 개발되고 있다. 따라서 본 연구를 통해서 차세대 항공우주분야 구동장치와 신개념 구동기들의 세부기술 및 발전방향을 제시하고자 한다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 C
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• pp.1629-1630
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• 2006

This paper describes a micro total analysis system ($\mu$ TAS) for detecting and digesting the target protein which includes a bead based temperature controllable microchip and computer based controllers for temperature and valve actuation. We firstly combined the temperature control function with a bead based microchip and realized the on-chip sequential reactions using two kinds of beads. The PEG-grafted bead, on which RNA aptamer was immobilized, was used for capturing and releasing the target protein. The target protein can be chosen by the type of RNA aptamer. In this paper, we used the RNA aptamer of HCV replicase. The trypsin coated bead was used for digesting the released protein prior to the matrix assisted laser desorption ionization time of flight mass spectrometer (MALDI TOF MS). Heat is applied for release of the captured protein binding on the bead, thermal denaturation and trypsin digestion. PDMS microchannel and PDMS micro pneumatic valves were also combined for the small volume liquid handling. The entire procedures for the detection and the digestion of the target protein were successfully carried out on a microchip without any other chemical treatment or off-chip handling using $20\;{\mu}l$ protein mixture within 20 min. We could acquire six matched peaks (7% sequence coverage) of HCV replicase.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.273-273
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• 2013

Recently, Point-of-care (POC) testing microdevices enable to do the patient monitoring, drug screening, pathogen detection in the outside of hospital. Immunochromatographic strip (ICS) is one of the diagnostic technologies which are widely applied to POC detection. Relatively low cost, simplicity to use, easy interpretations of the diagnostic results and high stability under any circumstances are representative advantages of POC diagnosis. It would provide colorimetric results more conveniently, if the genetic analysis microsystem incorporates the ICS as a detector part. In this work, we develop a reverse transcriptase-polymerase chain reaction (RT-PCR) microfluidic device integrated with a ROSGENE strip for colorimetric influenza H1N1 virus detection. The integrated RT-PCR- ROSGENE device is consist of four functional units which are a pneumatic micropump for sample loading, 2 ${\mu}L$ volume RT-PCR chamber for target gene amplification, a resistance temperature detector (RTD) electrode for temperature control, and a ROSGENE strip for target gene detection. The device was fabricated by combining four layers: First wafer is for RTD microfabrication, the second wafer is for PCR chamber at the bottom and micropump channel on the top, the third is the monolithic PDMS, and the fourth is the manifold for micropump operation. The RT-PCR was performed with subtype specific forward and reverse primers which were labeled with Texas-red, serving as a fluorescent hapten. A biotin-dUTP was used to insert biotin moieties in the PCR amplicons, during the RT-PCR. The RT-PCR amplicons were loaded in the sample application area, and they were conjugated with Au NP-labeled hapten-antibody. The test band embedded with streptavidins captures the biotin labeled amplicons and we can see violet colorimetric signals if the target gene was amplified with the control line. The off-chip RT-PCR amplicons of the influenza H1N1 virus were analyzed with a ROSGENE strip in comparison with an agarose gel electrophoresis. The intensities of test line was proportional to the template quantity and the detection sensitivity of the strip was better than that of the agarose gel. The test band of the ROSGENE strip could be observed with only 10 copies of a RNA template by the naked eyes. For the on-chip RT-PCR-ROSGENE experiments, a RT-PCR cocktail was injected into the chamber from the inlet reservoir to the waste outlet by the micro-pump actuation. After filling without bubbles inside the chamber, a RT-PCR thermal cycling was executed for 2 hours with all the microvalves closed to isolate the PCR chamber. After thermal cycling, the RT-PCR product was delivered to the attached ROSGENE strip through the outlet reservoir. After dropping 40 ${\mu}L$ of an eluant buffer at the end of the strip, the violet test line was detected as a H1N1 virus indicator, while the negative experiment only revealed a control line and while the positive experiment a control and a test line was appeared.