• 동의생리병리학회지
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• 제33권3호
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• pp.181-190
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• 2019

In South Korea, traffic accident patients can be treated under automobile insurance coverage. This study investigated the status of Korean medicine (KM) Automobile insurance system and usage status of main pharmacopuncture in KM clinic which reported that the largest number of automobile insurance fee claims among medical institutions. We surveyed 258 traffic accident patients who were treated at Namsangcheon KM clinic from 2014 to 2018 according to medical chart. The majority of the patients were male and thirties. In traffic accident situation, the highest distribution was car to car crash with 85.66% and 66.67% of the patients visited in the most acute phase. The most frequent treatment period was within 4 weeks and the number of treatments was 10 or less with 72.87%. In total results of treatment, the distribution was exellent with 10.08%, good with 46.90%, fair with 27.13% and poor with 15.89%, and the effective rate was 84.11%. The most frequent treatment period was within 4 weeks with 64.73% and the number of treatments was 10 or less with 72.87%. Of the 242 patients who received pharmacopunture, 91.5% were treated with HO, which was named after Honghwaja and TA, which was named after traffic accidents, and there were significant differences in the number of treatments and symptom improvement between the two groups. In this study, we confirmed the status of automobile insurance treatment and usage of main pharmacopuncture of single KM clinic with symptom improvement. This study can be regarded as one of the basis of KM treatment for the rapidly growing automobile insurance market.

• 한국산학기술학회논문지
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• 제17권12호
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• pp.198-204
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• 2016

본 연구는 대학생들이 인지하는 구강 내 증후증상과 공포감의 관련성을 연구하여 적절한 시기에 치료와 예방을 위한 방안을 모색하고자 2015년 9월부터 3개월간 부산지역에 거주하는 대학생을 대상으로 최종 288명을 최종 분석하였다. 공포수준은 모든 항목에서 여자에서 높게 나타났으며, 세부적으로는 약속 미룸(p=0.014), 진료 시 긴장(p=0.001), 진료 시 호흡 가쁨(p=0.009), 진료 시 심장 박동 수 증가(p=0.010), 약속 시 두려움(p=0.003), 치과도착 시 두려움(p=0.001), 대기실 대기 시 두려움(p=0.001), 치과냄새 두려움(p=0.006), 마취 시 두려움(p<0.001), 주사바늘 주입 시 두려움(p<0.001), 치아삭제용 기구를 볼 때 두려움(p<0.001), 치아삭제용 기구 소리 두려움(p<0.001), 치아삭제 시 느낌에 대한 두려움(p<0.001), 치석제거 시 두려움(p<0.001), 치과치료 전체에 대한 느낌 나쁨(p<0.001)에서 통계적으로 유의한 차이를 보였다. 증후증상 인지에 따른 공포수준은 충치가 있는 경우 진료회피(p=0.001), 생리적 반응(p=0.001), Dental Fear Survey(DFS) 전체(p=0.003), 깨진 치아가 있는 경우 진료회피(p=0.010), 자극요인(p=0.031), DFS전체(p=0.019)에서 공포수준이 높았다. 상실치아가 있는 경우 생리적 반응(p=0.019), DFS전체(p=0.033), 아픈 치아가 있는 경우 자극요인(p=0.031), 잇몸의 통증이 있는 경우 자극요인(p=0.013), DFS전체(p=0.034)에서 공포수준이 높았다. 따라서 통증을 느끼기 전 정기적 검진과 더불어서 예방적 처치를 할 수 있는 전반적인 시스템을 구축하여 치과를 내원하는 환자들로 하여금 공포감을 줄여 적절한 시기에 치료를 받을 수 있도록 하여야 할 것이다.

• 한국안전학회지
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• 제24권3호
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• pp.71-78
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• 2009

During a learning process, a human being is assumed to experience knowledge-based behaviors, rule-based behaviors, and skill-based behaviors sequentially if Rasmussen was right. If any psycho-physiological symptom to those different levels can be obtained, it can be useful as a measure whether a human being is fully trained and has gotten a skill in his work. Therefore, this study aimed to draw relationships between human performance measures and psycho-physiological measures while committing a computer-simulated pointing task by utilizing the power spectrum technique of EEG data, especially with the ratio of relative beta-to-alpha band power. The result showed that, during correct responses, the ratio came to stabilize as all the performance data went stable. However, response time was not a simple linear function of task difficulty level only, but a joint function of task characteristics as well as behavior levels. Comparing relative band power ratios from errors and correct responses, activated states of one's brain could be explained, and characteristics of the task could understood. To tell that of pointing task, correlations around C3, C4, P3, P4 and 01, 02 area were significant and high in correct response cases whereas most correlation coefficients went down in error cases standing for imbalance of psycho-motor functions. Though task difficulty was the only one factor that could influence on relative band power ratio with statistical significance, it should be comprehended to mean a different way of expression indicating task characteristics since at least error-some situation could be explained with the help of relative band power ratio that absolute band power failed.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3737-3740
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• 2014

Background: Abnormal uterine bleeding (AUB) is the most important symptom of endometrial hyperplasia and endometrial curettage (EC) is the gold standard diagnostic procedure. We present the results of patients who underwent EC for AUB and the efficacy of progestin administration in those with endometrial hyperplasia. Materials and Methods: A total of 415 female patients who presented to Duzce Public Hospital in 2011-2012 for AUB and who underwent EC were included. We determined the reasons for AUB, and females with hyperplasia were treated with 10 mg/day medroxyprogesterone acetate for 14 days/month or 160 mg/day megestrol acetate continuously for 3 months. We evaluated the efficacy of progestins for periods of three and/or six cycles by repeating EC. A statistical analysis of specific endometrial causes according to age of presentation was conducted using the chi-square test. Results: Among the 415 females (average age, 53.5 years) followed for 6 months, 186 had physiological changes (44.8%), 89 had simple hyperplasia (21.44%), 1 had atypical hyperplasia (0.2%), 6 had (1.44%) complex hyperplasia, 3 had (0.72%) atypical complex hyperplasia, and 5 had adenocarcinoma (1.2%). Regression rates were 72.7-100%, and the optimum results were observed after 6 months of hormonal therapy. Conclusions: The main cause of AUB was physiological change. Progestin therapy resulted in significant regression even in females with atypical hyperplasia.

• 대한한방내과학회지
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• 제28권3호
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• pp.560-569
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• 2007

Objectives : Ryodoraku is a physiological function test using electric current, and is closely related to skin sympathetic tone. Pulse analysis is known to reflect cardiovascular reactivity. There has been no report on the correlation between ryodoraku and pulse analysis in respiratory diseases. The present study examined the diagnostic values of ryodoraku and pulse analysis for respiratory disease patients Methods : For this study, we conducted ryodoraku and pulse analysis in 103 people including 79 respiratory disease outpatients who visited the $5^{th}$ Internal Department of the Oriental Medicine Hospital of Kyung Hee University during the period from January 1, 2003 to July 25, 2006, and 24 volunteers who did not have any respiratory symptoms or disease history. The respiratory disease patients were divided into five sub-groups according to their symptom: cough-sputum group, wheezing-dyspnea group ' nasal symptoms group. cold-prone group, and fatigue prone group. We compared the disease groups with the control group in six items as follows : mean ryodoraku, mean H1, mean elastic index, the percentage of those with mean ryodoraku below $40{\mu}A$, the percentage of those with HI beyond the physiological range, and the ratio of left : right of elastic index Results and Conclusions : Ryodoraku and pulse analysis were found to have a high value as quantitative diagnosis tools reflecting individuals' weakness and firmness. The results of this research suggest that ryodoraku and pulse analysis have value as tools for diagnosing respiratory diseases.

• 동의생리병리학회지
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• 제22권1호
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• pp.256-261
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• 2008

Anorexia is a common symptom in the elderly patients. Causes of anorexia in the elderly are very diverse and multifactorial. Causes include physiological changes associated with aging, mental disorders such as depression, anorexia tardive, dementia, medical diseases such as cancer(lung and gastrointestinal cancer), benign gastrointestinal disorders, cardiac disorders, pulmonary disease, thyroid disorders, infection. Medications such as digoxin, theophylline have also been implicated in the problem. No cause is found in about one quarter of patients. Management is directing at treating causes and providing nutritional support. In Oriental medicine, the appetite has close relation to Biwi. The main cause of anorexia is the insufficiency of Biwi. The physiology of Biwi is that Bi sends clarity(food essence) upward and Wi sends digested food downward. Specially if the physiologic function of Wi is disordered by various factors, Wi cannot send digested food downward. As a result, the anorexia can present by the disorder of Wi function. We experienced a case of an 74 years old female patient with ill-defined severe anorexia differentiated as Wijoongheohan. The patient was managed with fluid therapy and Jeonghyangsiche-tang. The anorexia and other symptoms improved continuously during hospitalization.

• 사상체질의학회지
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• 제21권2호
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• pp.79-86
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• 2009

1. Objective : This study aimed to know the concordance coefficient and diagnostic trend of 6 Sasang constitution diagnosis factors among experts, which are important to diagnose Sasang constitution. 2. Methods : We suggested each 100 cases containing body shape, face, temperament, physiological and pathological symptom and constitutional drug response to 2 groups experts, and researched expert opinions. We analyzed concordance coefficient with Kendall's coefficient of concordance W. 3. Results : 1) Experts agreed with 167(82.5%) diagnosis results of cases, but there were 33 cases(17.5%), with which even one expert disagreed 2) The concordance of priority order of Sasang constitutional factors was significantly associated within expert. 3) Experts put the priority concordance to drug response and Face, body shape, voice and Pathological and physiological symptoms in order. 4) In case by case, concordance coefficient was 47(55.9%) in group 1, 9(10.8%) in group 2, 56 (33.5%) in total. 4. Conclusions : Experts made much account of drug responses and faces in diagnosing Sasang constitution. but there were different opinions in concordance coefficient. So Sasang Constitution Diagnosis Guideline is necessary to integrate experts opinions.

• 환경생물
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• 제35권4호
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• pp.461-467
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• 2017

Shrimps infected with WSSV(White Spot Syndrome Virus) generally exhibit white spots in their inner space of carapaces as an acute clinical sign. In an effort to identify the correlation between this acute clinical sign and the condition, the index factors (RNA/DNA concentration and ratio, trypsin activity) were analyzed. A total 580 farmed Fenneropenaeus chinensis and 130 Lithopenaeus vannamei were collected from western and southern fifteen outdoor ponds in Korea. The status of the white spot pathology was divided into four stages (stage 0, stage I, stage II, and stage III), in accordance with the clinical signs as to the size and area of white spots. A significant decrease in RNA concentration and RNA/DNA ratio for multi-infected fleshy prawn (WSSV and vibrio sp.) occurred during the stage III (the whole carapace is covered with a white spot). In particular, RNA/DNA ratio was significantly lower as $1.47{\pm}0.04$ than other groups. A similar trend was also found in the single infection (WSSV), but the decrease was less than the multi-infection. In the species comparison, both species were vulnerable to the multi-infection, but L. vannamei was more sensitive than F. chinensis(ANOVA, p<0.05): A significant decrease in RNA concentration and RNA/DNA ratio was first found in stage II for the former species, while it was found in stage III for the latter species. Trypsin activity was also showed a similar tendency with nucleic acid variation. Multi-infected shrimp showed drastically decrease of trypsin activity. According to the results, clinical signs of the white spot under carapace have an only physiological effect on shrimp if they covered entirely with white spots.

• 한국산림과학회지
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• 제97권6호
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• pp.570-575
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• 2008

본 연구는 국내산 4년생 해송을 대상으로 소나무재선충을 인공접종하여 나타나는 병징의 발달과 묘목내 수분함량 및 선충밀도의 변화를 조사 및 분석하여 소나무재선충에 의한 생리적 변화과정 구명에 사용될 수 있는 기초 자료로 활용되고자 수행되었다. 소나무재선충 인공접종 후 20일을 기점으로 외부적으로 잎의 변색 그리고 내부적으로 접종 부위 위 아래의 목부 건조 및 수 갈변 현상이 나타났다. 그러나 접종 후 10일에 대조구 묘목과 접종목의 목부 및 피층의 건조상태는 차이를 나타내어 목부 건조는 접종 후 10일 경부터 진행이 되고 있음을 알 수 있었다. 소나무재선충 밀도는 접종 후 5일과 10일 사이에서 소폭의 증가를 보였으나 외부적 또는 내부적 피해증상이 나타난 10일과 20일 사이에서는 급격한 증가를 보였다. 소나무재선충 접종 후 시간이 경과함에 따라 감염목의 줄기수분함량 및 당년생 잎과 줄기의 상대수분함량은 꾸준히 감소하였다. 소나무재선충의 개체 수가 증가함에 따라 줄기수분함량, 당년생 가지 및 잎의 상대수분함량이 유의적으로 감소하여, 소나무재선충 증식은 병 발달 및 수체내 목부의 수분건조 현상과 밀접한 상관관계를 보이지만 묘목의 고사와 함께 재선충 번식이 현격히 줄어드는 것으로 나타났다.

• 한국약용작물학회지
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• 제22권1호
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• pp.32-37
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• 2014

To study the cause of physiological disorder in leaf of ginseng cultivated at paddy soil, the degree of brown-colored symptom (BCS) and the contents of inorganic matter in leaf were investigated by irrigating the solution of ferric and ferrous iron of 0.1 ~ 2.0%, and citric acid of 1.0 ~ 4.0% on bed soil, respectively. Ratio of BCS by variety was as high as 85.0% in Yoenpoong, while it was as low as 5.4%, 7.5% in Chunpoong and Hwangsook, respectively. The contents of inorganic matter of leaf in Yoenpoong were lower in $P_2O_5$, Ca, and Mg, while it were higher in K, Fe, and Mn than other variety. Iron solution caused BCS more distinctly when each ferric and ferrous iron were dissolved with 1.0% citric acid than when each iron was dissolved without citric acid. Ferric iron caused BCS more effectively than ferrous iron. BCS occurred in 4.0% citric acid was as same as 2.0% ferric iron mixed with 1.0% citric acid. Low $P_2O_5$ and high Fe content in leaf appeared in both of artificial and natural symptoms. We concluded that excessive Fe uptake caused BCS to leaf because the solubility of iron was increased in condition of low soil pH.