• Title/Summary/Keyword: physiochemical change

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Pharmacopuncture of Bauhinia variegata Nanoemulsion Formulation against Diabetic Peripheral Neuropathic Pain

  • Gupta, Pushpraj S;Singh, Sunil K;Tripathi, Abhishek K
    • Journal of Pharmacopuncture
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    • v.23 no.1
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    • pp.30-36
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    • 2020
  • Objectives: The objective of the study was to prepare Bauhinia variegata loaded nanoemulsion(formulation and determine the efficacy of herbal drug formulation against diabetic peripheral neuropathic pain through acupuncture technique. Methods: Nine different ba tches of nanoemulsion (NE1 NE9) of BVN was prepared by varying the Smix ratio and the concentration of oil. BVN was characterized to determine particle size, shape, zeta potential, polydispersity index, optical transmittance, drug release profile and stora ge stability. The optimized formulation was subjected to plantar test, behavioral tests of neuropathic pain and Von Frey filament stimulation test. Diabetes was induced by intraperitoneal injection of freshly prepared solution of Streptozotocin (60 mg/kg) to the experimental rats. Animals were made diabetic divided into four groups, Group I was untreated normal control group, Group II was diabetic control group, Group III was Bauhinia variegata extract ( treated group (100 mg/kg/day, p.o) and Group IV was BVN treated groups (100 mg/kg/day, p.o) acute and chronically. Results: The prepared B. variegata loaded nanoemulsion was nanosized (124 nm), spherical, uniform and stable over the period of 180 days with no change in physiochemical properties. The bl ood glucose and body weight of animals was normalizing after four weeks of treatment that was significant with BVN in comparison to diabetic control group. The chronic administration of BVN significantly (P<0.001) decreased hind paw withdrawal latency an d attenuated mechanical allodynia as compared with diabetic rats. Conclusion: Thus, BVN may be an effective drug formulation against diabetic peripheral neuropathic pain.

Shelf-life Extension of Raw Oyster Crassostrea gigas by Depuration Process (인공정화에 의한 참굴(Crassostrea gigas)의 유통기한 연장)

  • Lee, Do-Ha;Kang, Dong-Min;Park, Seul-Ki;Jeong, Min-Chul;Kang, Min-Gyun;Jo, Du-Min;Lee, Jae-Hwa;Lee, Da-Eun;Sim, Yoon-Ah;Jeong, Geum-Jae;Cho, Kyung-Jin;Kim, Young-Mog
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.6
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    • pp.842-850
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    • 2020
  • The objective of this study was to evaluate the effect of the depuration process (artificial seawater sterilization using UV light) for extending the shelf life of raw oyster Crassostrea gigas and maintaining food quality. To confirm the effects of depuration, microbiological (viable cell count) and several physiochemical analyses (pH and glycogen levels in shucked oyster and pH, soluble protein, and turbidity in filling water) were carried out during the storage of raw oysters. The results showed that depuration could effectively extend the shelf life (2-3 days) of raw oysters with minimal change in food quality, including pH and glycogen content. Thus, the depuration process proposed in this study could successfully be applied to processing practices for other shellfish to extend their shelf life and contribute to the management of seafood safety issues.

Multi-responsive hydrogel cross-linked synthesized spiropyran-based hydrophilic cross-linker (스피로피란 기반 친수성 가교제를 활용한 다중 자극 감응형 하이드로젤)

  • Jeong, Hye-Won;Kim, Sang Jin;Heo, Eun-Jin;Shin, Sung Gyu;Han, Sa Ra;Jeong, Jae Hyun
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.1
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    • pp.126-135
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    • 2021
  • Stimuli-responsive hydrogels are being extensively studied to alter their physiochemical properties in response to external changes such as temperature, pH, light and mechanical stress. This study reports multi-responsive hydrogel having optical change response to external stress. First, we synthesized a novel spiropyran cross-linker successfully by grafting poly(ethylene glycol) diacrylate (PEGDA) on both side of spiropyran and introduced to hydrogel. In the results, the yellow spriopyran structure was conversed to purple merocyaine structure by internal stress during swelling of the hydrogels cross-linked with the SP-PEGDAs. Also, the hydrogel could be visualized the swelling and deswelling process in response to pH, by converting MC and prontonated MC structure.

Groundwater and Soil Pollution Caused by Forest Fires, and Its Effects on the Distribution and Transport of Radionuclides in Subsurface Environments: Review (산불에 의한 지하수 토양 환경오염과 방사성 물질 분포 및 거동 영향 고찰)

  • Hyojin Bae;Sungwook Choung;Jungsun Oh;Jina Jeong
    • Economic and Environmental Geology
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    • v.56 no.5
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    • pp.501-514
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    • 2023
  • Forest fires can generate numerous pollutants through the combustion of vegetation and cause serious environmental problems. The global warming and climate change will increase the frequency and scale of forest fires across the world. In Korea, many nuclear power plants (NPPs) are located in the East Coast where large-scale forest fires frequently occur. Therefore, understanding the sorption and transport characteristics of radionuclides in the forest fire areas is required against the severe accidents in NPPs. This article reviewed the physiochemical changes and contamination of groundwater and soil environments after forest fires, and discussed sorption and transport of radionuclides in the subsurface environment of burned forest area. We considered the geochemical factors of subsurface environment changed by forest fire. Moreover, we highlighted the need for studies on changes and contamination of subsurface environments caused by forest fires to understand more specific mechanisms.

The Effect of Washing of Carcasses with Sodium Hypochlorite Solution and Vacuum Packaging on the Microbiological and Physiochemical Quality of the Breast Meat from Old Hen during Storage at 4℃ (차아염소산나트륨 세척 및 진공 포장이 노계 가슴육의 냉장 저장 중 미생물학적 및 이화학적 품질에 미치는 영향)

  • Na, Jae Cheon;Kim, Sun Hyo;Jung, Samooel;Lee, Soo Kee;Kang, Hwan Gu;Choi, Hee Cheol;Jo, Cheorun
    • Korean Journal of Poultry Science
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    • v.40 no.4
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    • pp.327-336
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    • 2013
  • This study was conducted to examine the effect of spray-washing old hens (old laying hens, old molting hens and old breeder hens) carcasses with sodium hypochlorite (50 ppm) solution and vacuum packaging on the microbiological and physiochemical quality of breast meat during storage at $4^{\circ}C$. There were no significant differences of cooking loss and texture among breast meats from different birds with spray-washing by water or sodium hypochlorite solution before storage. The numbers of total aerobic bacteria of aerobically packaged and only water-washed breast meat were higher than 7 Log CFU/g (the limitation population for spoilage of meat) after 7 days of storage. However, the numbers of total aerobic bacteria of vacuum packaged breast meat washed by sodium hypochlorite solution were lower than 7 Log CFU/g even after 14 days of storage. The volatile basic nitrogen content of vacuum packaged breast meat were lower than 20 mg% (the limitation value for spoilage of meat) regardless of the washing method, while those of aerobically packaged breast meat washed by tap water and sodium hypochlorite solution were 41.1 and 20.1 mg%, respectively. In addition, lipid oxidation and change of pH in breast meat was inhibited by vacuum packaging when compared with that of aerobic packaged breast meat during storage. Therefore, the results indicated that the washing old hen's carcasses with sodium hypochlorite (50 ppm) solution and vacuum packaging could improve the shelf-life of meat from old birds. This result can provide the basic information for industry, which are seeking for export market.

Effects of Complex Carbohydrase Treatment on Physiological Activities of Pear Peel and Core (탄수화물 분해효소 처리에 의한 배 과피와 과심의 항산화 생리활성 증대효과)

  • Lee, Pyeong Hwa;Park, Su Yeon;Jang, Tae Hoon;Yim, Sun-Hee;Nam, Seung-Hee;In, Man-Jin;Kim, Dong Chung;Chae, Hee Jeong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.3
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    • pp.404-410
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    • 2014
  • The effects of treatment with various complex carbohydrases such as Pectinex, Celluclast, Viscozyme, and Ultraflo on the physiochemical properties, polyphenol extraction yields and antioxidant activities of pear peel and pear core were investigated. When pear peel and pear core were treated with complex carbohydrases, the soluble solid content of peel increased, whereas it did not change significantly in the case of pear core. When pear peel and pear core were treated with Pectinex, significant improvement of soluble solid content was observed along with the highest extraction yield of reducing sugar content. Total sugar content increased in most of the enzyme treatment groups. In the case of pear peel, the Viscozyme treatment group showed the highest total polyphenol contents, total flavonoid contents, DPPH radical scavenging activity, ABTS radical scavenging activity, and SOD-like activity. When the flesh and core of pear were treated with Celluclast, total polyphenol contents increased. All enzyme treatment groups except for the Ultraflo treatment group showed increases in total flavonoid contents. With regard to pear flesh, the Celluclast group showed the highest DPPH radical scavenging activity. When pear core was treated with the four complex carbohydrases, DPPH radical scavenging activity and ABTS radical scavenging activity did not increase significantly. However, the SOD-like activity of all enzyme treatment groups significantly increased. Consequently, dry matter and soluble solid contents, polyphenol content, and antioxidant activity of pear peel and core could be improved by complex carbohydrase treatment.

Change of Electrochemical Characteristics Due to the Fe Doping in Lithium Manganese Oxide Electrode

  • Ju Jeh Beck;Kang Tae Young;Cho Sung Jin;Sohn Tae Won
    • Journal of the Korean Electrochemical Society
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    • v.7 no.3
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    • pp.131-137
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    • 2004
  • Sol-gel method which provides better electrochemical and physiochemical properties compared to the solid-state method was used to synthesize the material of $LiFe_yMn_{2-y}O_4$. Fe was substituted to increase the structural stability so that the effects of the substitution amount and sintering temperature were analyzed. XRD was used for the structural analysis of produced material, which in turn, showed the same cubic spinel structure as $LiMn_2O_4$ despite the substitution of $Fe^{3+}$. During the synthesis of $LiFe_yMn_{2-y}O_4$, as the sintering temperature and the doping amount of Fe(y=0.05, 0.1, 0.2)were increased, grain growth proceeded which in turn, showed a high crystalline and a large grain size, certain morphology with narrow specific surface area and large pore volume distribution was observed. In order to examine the ability for the practical use of the battery, charge-discharge tests were undertaken. When the substitution amount of $Fe^{3+}\;into\;LiMn_2O_4$ increased, the initial discharge capacity showed a tendency to decrease within the region of $3.0\~4.2V$ but when charge-discharge processes were repeated, other capacity maintenance properties turned out to be outstanding. In addition, when the sintering temperature was $800\~850^{\circ}C$, the initial capacity was small but showed very stable cycle performance. According to EVS(electrochemical voltage spectroscopy) test, $LiFe_yMn_{2-y}O_4(y=0,\;0.05,\;0.1,\;0.2)$ showed two plateau region and the typical peaks of manganese spinel structure when the substitution amount of $Fe^{3+}$ increased, the peak value at about 4.15V during the charge-discharge process showed a tendency to decrease. From the previous results, the local distortion due to the biphase within the region near 4.15V during the lithium extraction gave a phase transition to a more suitable single phase. When the transition was derived, the discharge capacity decreased. However the cycle performance showed an outstanding result.

The Physicochemical and Quality Properties of the Bread Added with Soy Fiber Powder (콩식이섬유를 첨가한 식빵의 이화학적 및 품질 특성)

  • Lee, Myung-Ho;Byun, Jong-Beom;Kim, Sun-Kyung;Choi, Young-Sim
    • Culinary science and hospitality research
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    • v.18 no.1
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    • pp.1-14
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    • 2012
  • This study examines the physiochemical and quality properties of the bread added with soy fiber powder to promote the intake of soy fiber. For this study, the powder for making bread was mixed with soy fiber, wheat flour and SF-1450 and SF-1260 at the ratio of 0~12% each. The ratios of the edible fiber contained in the soy fiber power samples were 72.0% in the SF-1450 sample and 67.8% in the SF-1260 sample. The mixograph characteristics tended to be conspicuons in proportion to the amount of the soy fiber added at midline peak height, width at peak and, width at 8.00. The specific volume of the bread tended to decrease significantly as the amount of the soy fiber increased from 2 to 12%. In terms of crust chromaticity change, L-value increased more significantly in the samples added with 4 to 12% than the control. For a-value, SF-1450 in the samples with 6 to 12% and SF-1260 in the samples with 8 to 12% more significantly decreased than the control. For such characteristics of texture as hardness, SF-1450 in the samples with 10 to 12% and SF-1260 in the samples with 6 to 12% increased more than the control. As discussed above, the sensual characteristics of the white pan bread with soy fiber added tended to be worse as the amount of the additive increased, compared with the control samples. Summing up the results of the physico-chemical analysis and the overall acceptability, those samples with 2~4% of SF-1450 and 2% of SF-1260 were found excellent.

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Effect of Storage Period and Temperature on the Characteristics Related with Rice Quality (벼 저장온도 및 저장기간이 미질 관련 형질에 미치는 영향)

  • Ha, Ki-Yong;Park, Hong-Kyu;Ko, Jae-Kwon;Kim, Chung-Kon;Choi, Yoon-Hee;Kim, Ki-Young;Kim, Young-Doo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.51 no.spc1
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    • pp.25-29
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    • 2006
  • This study was carried out to investigate physiochemical properties and factors related with eating quality in the rice and paddy rice with different storage methods. As storage period was longer and temperature was higher, the b values of chromaticity and degree of fatty acid were increased, and the b value of room temp. was higher than that of low temp. In the varieties, the b value of Samcheonbyeo was the highest among varieties. also b value of Gancheokbyeo and Sae-gyehwabyeo were more increased than those of Dongjinbyeo and Hojinbyeo. Toyo meter values were significantly different according to storage temperature and period. Toyo meter values in storage of low temp. small decreased from 8 month after storages and that of loom temp. was severe decreased from 2 month after storages. In storage of low temp, Toyo meter values in storage of low temp. $(5{\sim}10^{\circ}C)$ was the lowest, and those of the early varieties were the most decreased. Degree of fatty acid of brown rice was increased from 2 month after storages and those of low temp. was severe increased. So, they made rice quality and eating quality to be deteriorated.

The Change of Free Sugar, Hesperidine, Naringin, Flavonoid Contents and Antihypertensive Activities of Yuza Variety according to Harvest Date (유자의 종류별 수확시기에 따른 유리당, 헤스페리딘, 나린진, 플라보노이드 함량과 항고혈압 활성 변화)

  • Hwang, Seong-Hee;Jang, Jae-Seon;Kim, Min-Jeong;Kim, Kang-Sung
    • The Korean Journal of Food And Nutrition
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    • v.27 no.6
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    • pp.1051-1058
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    • 2014
  • Yuza (Citrus junos) had 3 varieties and they had variable physiochemical properties. This study analyzed free sugar, hesperidine, naringin, flavonoid contents and antihypertensive activities according to variety and harvest time of Yuza. Three Yuza varieties, native (C. junos I), improved I (C. junos I + Poncirus trifoliata), improved II (C. junos I + C. junos II) were used. Harvest time could influence biochemical properties of Yuza such as acidity and $^{\circ}brix$. When the Yuza harvested at behind of season, the sugar/acid ratio went up because the acidity was decreased but sugar content was increased. Fructose content was dramatically high at November, Yuza of the season. Total flavonoids was high in pulp parts of improved II and in juice of native one harvested at October. The content of hesperidin and naringin in peels and juices were high in immature fruits fresh-picked at July since then they were decreased steadily and there were no difference according to varieties. The angiotensin converting enzyme (ACE) inhibition was powerful at pulp of Yuza in particular native one picked at November.