• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of the Pharmaceutical Society of Korea
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• pp.158.2-159
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• 2001

• 생약학회지
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• 제25권1호
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• pp.70-72
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• 1994

From the herb of Artemisia princeps var. orientalis o-coumaric acid and 4,5-O-dicaffeoylquinic acid were isolated and identified by chemical and spectral analysis.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.161.3-162
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• 2002

• Bulletin of the Korean Chemical Society
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• 제31권4호
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• pp.1070-1072
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• 2010

• Natural Product Sciences
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• 제8권4호
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• pp.111-126
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• 2002

The chemistry of secondary products from Acanthopanax species and their pharmacological activities were reviewed. A nitrogenous compound, a furan compound, a quinoid, benzoids, coumarins, phenylpropanoids, lignans, flavonoids, terpenoids, phytosterols, polyacetylenes, a pyrimidine, cyclitols, monosaccharides and an aliphatic alcohol have been isolated from Acanthopanax species and have been shown to have various levels of activities such as anti-bacterial, anti-cancer, anti-gout, anti-hepatitis, anti-hyperglycemic, anti-inflammatory, anti-leishmanicidic, anti-oxidant, anti-pyretic, anti-xanthine oxidase, choleretic, hemostatic, hypocholesterolemic, immunostimulatory and radioprotectant effects, etc.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of the Pharmaceutical Society of Korea
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• pp.159.1-159.1
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• 2001

• Archives of Pharmacal Research
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• 제12권1호
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• pp.22-25
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• 1989

Ethylacetate fraction from Orobanche crenata, contained two phenylpropanoid glycosides, exhibited some pharmacological properties. It was found to be non-toxic to rats in oral doses up to 500mg/100gm body weight. In large doses, it lowered the arterial blood pressure of anaethetised rats, and produced significant analgesic effect in mice and diuretic effect in rats. It further showed smooth muscle relaxant and antispasmodic effects in the isolated rabbit intestine and guinea-pig ileum respectively.

• 한국약용작물학회지
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• 제5권2호
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• pp.126-130
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• 1997

$^1H-NMR,\;^{13}C-NMR$, Dept. NMR의 spectrum으로 compound 1은 safrole로, compoud 2은 o-methyleugenol로 추정(推定)되었으며 처리농도별(處理濃度別) 발아억제(發芽抑制) 효과조사(效果調査)에서 발아억제 물질로 추정한 safrole은 25mg/ml의 처리에서도 발아 및 생육억제 효과를 나타내지 않았다. o-methyleugenol의 경우는 5mg/ml의 처리(處理)로 최종발아(最終發芽)는 무처리구에 비해 58% 저해하였으며, 그리고 25mg/ml에서도 92%, 생육(生育)에는 100%의 저해도(沮害度)를 나타내었다. 이상(以上)의 결과(結果)를 보면 o-methyleugenol은 세신의 강(强)한 발아저해활성 물질의 하나로 처음 확인되었으며 천연(天然) 제초제(除草劑)로서의 개발(開發) 가능성(可能性)은 추후 재검증(再檢證)해 보아야 하겠다.

• Natural Product Sciences
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• 제14권2호
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• pp.90-94
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• 2008

Two sesquiterpenes (1 - 2), a tetralone (3), and two phenylpropanoids (4 - 5) were isolated from the stem bark of Magnolia obovata Thunberg (Magnoliaceae) through repeated column chromatography. Their structures were identified as ${\beta}-eudesmol$ (1), cryptomeridiol (2), 4R-4,8-dihydroxy-${\beta}-tetralone$ (3), trans-pcoumaryl aldehyde (4), and p-coumaric acid (5) on the basis of spectroscopic analysis including two dimensional NMR and mass. Compounds 1 - 3 were tested in vitro for their cytotoxic activity against the K562, HeLa, A549, and HCT116 cancer cell lines. However, compounds 1 - 3 were inactive in this assay system.

• Natural Product Sciences
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• 제14권3호
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• pp.196-201
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• 2008

Five neolignans (1 - 4, 8), two sesquiterpene-lignans (5 - 6), and two phenylpropanoids (7, 9) were isolated from the stem bark of Magnolia obovata Thunberg (Magnoliaceae) by repeated column chromatography. The structures of isolated compounds were identified as 4-methoxyhonokiol (1), obovatol (2), magnolol (3), honokiol (4), eudeshonokiol B (5), eudesobovatol B (6), coumaric acid (7), magnaldehyde B (8), and ${\rho}-coumaric$ acid (9) on the basis of spectroscopic analysis including 2D-NMR and MS data. Compounds 1 - 9 were evaluated for their anti-complement activities against the classical pathway of the complement system. Of them, compound 8 showed significant anti-complement activity on the classical pathway with $IC_{50}$ value of 102.7 ${\mu}M$, whereas compounds 1 - 7 and 9 were inactive. This result indicated that an aldehyde group in the neolignan is important for the anti-complement activity against the classical pathway.