• Title/Summary/Keyword: pharmaceutical service

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Diversification Strategy through Market Creation: The Case of CJ Group

  • Jeong, Jaeseok;Kim, Nam Jung;Lim, Hyunjoo;Kang, Hyoung Goo;Moon, Junghoon
    • Asia Marketing Journal
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    • v.15 no.4
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    • pp.1-32
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    • 2014
  • The purpose of this paper is to investigate upon a diversification strategy through market creation of CJ Group, which has contributed in positioning of the firm as one of the leading conglomerates in South Korea. With such objective, the background of CJ Group, followed by its business diversification strategies were explored, with reference to several case studies. The history of CJ Group began with establishment of CheilJedang Industrial Corporation in 1953, as the first domestic sugar producer and exporter of South Korea. The corporation gradually expanded its business ever since at both national and global level, to include the fields of food production, pharmaceutical, biotechnology, and life chemicals. Later, CheilJedang (CJ) Group was established as an affiliate of CheilJedang Industrial Corporation. With such independence, extension of business has been witnessed across the industries of media, entertainment, finance, information technology and distribution. Thus, the current CJ Group pursues to define itself as a progressive global living culture company with four major business categories from food and food service, biotechnology, entertainment and media, and logistics. Despite its success in today's market, CJ Group underwent hardships in its business diversification in 1990s due to indiscreet management, along with the Asian financial crisis. Here, many firms overcame the financial difficulties by taking advantage of the exchange rate for overseas expansion. Though, CJ Group tried to differentiate itself by focusing on the domestic market by creating something out of nothing. Hence, CJ Group takes a unique position among many cases of business diversification and their categorization. In an effort to identify and classify the types of growth experienced by the top 30 companies in South Korea, the firms were categorized into four groups according to their diversification strategies adapted after the Asian financial crisis. Based on the mode and time of entry, corporations were identified either as the 'Explorer', 'Invader', 'Venture Capitalist', or 'Assimilator'. Here, the majority of the firms showed the qualities of Invader, entering mature markets through large-scaled mergers and acquisitions. However, CJ Group was the only firm that was categorized as an Explorer, for its focus on the newly emerging service sector in culture-contents industry. This diversification strategy through market creation is worth examining, due to its contribution in generating simultaneous growth between the market and the company itself. Diverse brands of CJ Group have been referred to as case studies in this regard, from 'Hatban', 'Cine de Chef', 'VIPS' to 'CJ GLS'. These four businesses, each to represent processed food, film, restaurant service, and logistics industries respectively, show CJ Group's effectiveness in creating a whole new category of goods and services that are innovative. In fact, such businesses not only contributed in advancement of consumers' wellbeing, but toward generating additional value and employment. It is true that the diversification strategy of CJ Group requires long-term capital investment with high risk, compared to the other strategies mentioned in the paper. However, this model does create high employment and additional values that are positive to both the society and the firm itself. Therefore, the paper comes to a conclusion that the diversification strategy through market creation conveys the most positive impact relative to the others.

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Identification and Characterization of Aspergillus oryzae Isolated from Soybean Products in Sunchang County (순창군 장류로부터 분리된 황국균의 동정 및 특성)

  • Lim, Eunmi;Lee, Ji Young;Elgabbar, Mohammed A. Abdo;Han, Kap-Hoon;Lee, Bo-Soon;Cho, Yong Sik;Kim, Hyoun-Young
    • The Korean Journal of Mycology
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    • v.42 no.4
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    • pp.282-288
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    • 2014
  • In this study, we attempted to isolate fungi from soybean fermented foods produced in Sunchang County and to identify Aspergillus oryzae from fungal isolates. Ten fungal isolates were identified with ${\beta}$-tubulin gene. According to the sequences of ${\beta}$-tubulin gene, ten fungal isolates were identified as A. oryzae/flavus complex. For further identification of the ten of fungal isolates, omtA gene, one gene of the aflatoxin biosynthesis gene cluster, was sequenced and the sequences were compared with those of A. oryzae and A. flavus strains from the GenBank database. In addition, identification of the ten fungal isolates was further confirmed using the PCR amplicon of norB and cypA intergenic region, in which a deletion was recognized relative to A. flavus and A. parasiticus. The amplicon size of the ten fungal isolate strains was smaller than those of A. flavus and A. parasiticus, but the same as that of the reference A. oryzae strain. These results indicated that the ten isolates should be identified as A. oryzae. The protease activity in rice koji made with 6, 13, 17, 27, 37 and 38 of strain, respectively was twice higher than that in control. The kojis made with nine of the A. oryzae isolates, respectively, did not produce aflatoxin, suggesting that the strains could possibly be used as starters for soybean products.

Systemic Review of Clinical Studies about Oriental Medical Treatment of Cancer in Korea (국내에 보고된 한국 한의학의 암치료 임상연구에 대한 계통적 고찰)

  • Park, Bong-Ky;Lee, Jong-Hoon;Cho, Chong-Kwan;Shin, Hyun-Kyu;Eom, Seok-Ki;Yoo, Hwa-Seung
    • The Journal of Internal Korean Medicine
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    • v.29 no.4
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    • pp.1061-1074
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    • 2008
  • Objectives : Recently, the number of cancer patients who use complementary and alternative medicine (CAM), including oriental medicine, are increasing. Also, evidence for efficacy and safety of cancer CAM is reported continuously. This study was designed to evaluate the quality of the published papers for clinical studies about oriental medical cancer treatment in Korea. Methods : We searched for clinical research papers on the websites of the Korean oriental medical society and subsidiary academies, Korean traditional knowledge portal. Koreanstudies information service system (KISS), etc. We used the reference words 'cancer', 'malignant tumor', 'leukemia', 'lymphoma', 'multiple myeloma', 'melanoma', etc, We then chose studies that had been presented between 1991 and 2008 and analyzed them by publication year, design, cancer type, intervention, subject and journal. Results : There were 86 clinical research papers that were published between 1991 and 2008. The number of clinical studies has increased in a time-dependent manner. Case reports and case series studies account for 78% of total clinical research. Studies of lung cancer account for 17%. Studies of cancer-related symptoms of cancer patients account for 38%. Studies of Hang-Am-Dan account for 33%. Studies published in the journal of the Korean Society of Oriental Internal Medicine account for 35%. Conclusion : The clinical research papers about oriental medicine are increasing over time, but most of the studies are retrospective case reports or case series. Well-designed and prospective clinical trials would be recommended to provide more reliable evidence.

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The Quality of Life in COPD Patients according to Gender: Based on the 4th Korea National Health and Nutrition Examination Survey (제4기 국민건강영양조사에 기초한 만성 폐쇄성폐질환자의 성별에 따른 삶의 질 분석)

  • Kang, Kyung Sook;Na, Soon Ok;Yu, Young Beob;Shin, Jun Ho
    • Research in Community and Public Health Nursing
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    • v.26 no.2
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    • pp.61-68
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    • 2015
  • Purpose: In this study, we performed a comparative analysis on the quality of life (QoL) in male and female chronic obstructive pulmonary disease (COPD) patients based on the 4th Korea National Health and Nutrition Examination Survey (KNHANES IV) from 2007 to 2010. Methods: We extracted the socio-demographic and clinical data of 1,218 COPD patients including 874 men and 344 women from the KNHANES IV database. Descriptive statistics and correlation test were used to analyze the data. In order to find factors associated with QoL of COPD patients, we conducted multivariate linear regression analysis. Results: Infrequency analysis, the educational level and income were lower in the female COPD patients than in the male ones. The QoL indexes including mobility, self-care, activities of daily living, discomfort, anxiety, and depression were significantly worse in the female of COPD patients than in the male ones (p<.01).Conclusion: Our study indicates that QoL of female COPD patients should be improved on the educational, economic, and healthcare aspects.

Design of Convergence Platform for companion animal Personalized Services (반려동물 개인화서비스를 위한 융합 플랫폼 설계)

  • Kim, Sam-Taek
    • Journal of the Korea Convergence Society
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    • v.7 no.6
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    • pp.29-34
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    • 2016
  • Nowadays, real-time devices that provide health care for a companion animal is being developed by IoT technology and its demand such as smart puppy tag is increasing. However, it is difficult for IoT devices of companion animals to process complex nature due to miniaturized hardware and constructive nature. There is a clear limit to custom advanced features like health care implementation. This paper designs an integrated platform with statistical analysis which makes it possible to customized services such as feed production, pharmaceutical production, and health care for each companion animal. Middleware that collects sensor information, customer's spending pattern and information from Social Network Service is also designed by making use of IoT devices which companion animals wear. Furthermore, the paper designed data analyzer which analyzes and refines data from collected information that can be applied to personalized services.

Comparison of Biological Activities of Fermented Codonopsis lanceolata and Fresh Codonopsis lanceolata (생더덕과 발효더덕의 유용생리활성 비교)

  • Kim, Seung-Seop;Ha, Ji-Hye;Jeong, Myoung-Hoon;Ahn, Ju-Hee;Yoon, Won-Byung;Park, Sung-Jin;Seong, Dong-Ho;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.17 no.4
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    • pp.280-285
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    • 2009
  • Both fresh Codonopsis lanceolata and lactic acid bacteria fermented Codonopsis lanceolata were extracted with water at $100^{\circ}C$, and tested for anticancer activity using several human cancer cell lines. The fermented extracts inhibited the growth of hepatocellular carcinoma cells up to 90%, compared to 75% for fresh Codonopsis lanceolata. The extracts of cytotoxicity on human normal lung cells (HEK293) were as low as 15%. Especially, human hepatocellular carcinoma cell were more efficiently inhibited than other cells. This extract also inhibited $\alpha$-glucosidase activity up to 60% at 1.0mg/$m{\ell}$. This fermented extracts showed the inhibition potency on tyrosinase by 25% at 1.0mg/$m{\ell}$. From the results, the fermented Codonopsis lanceolata enhanced several biological activities up to $20{\sim}30%$, compared to those from fresh Codonopsis lanceolata. It implies that fermentation process could be one of useful methods of utilizing low quality Codonopsis lanceolata. Because this process could yield high amounts of biologically active compounds by the help of microbial growth.

Mobile Healthcare System Based on Bluetooth Medical Device

  • Kim, Jeong-Heon;Lee, Seung-Chul;Lee, Boon-Giin;Chung, Wan-Young
    • Journal of Sensor Science and Technology
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    • v.21 no.4
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    • pp.241-248
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    • 2012
  • Recently healthcare industry such as pharmaceutical, medical device and healthcare service technology is growing significantly. Mobile healthcare has attracted big attention due to IT convergence technology. Paradigm of healthcare has been changed from the 1st generation(communicable disease prevention) and the 2nd generation(treatment of disease due to extended life expectancy) to the 3rd generation(extended life expectancy due to prevention and control). In our study, we suggest the 3rd generation mobile healthcare system using Bluetooth based wearable ECG monitoring system and smart phone technology. The mobile healthcare system consists of wearable shirts with Bluetooth communication module, ECG sensor, battery, and mobile phone. The ECG data is obtained by a miniaturized sensor and the data is transferred to a mobile phone using Bluetooth communication. Then, user can monitor his/her own ECG signal on an application using Android in mobile phone. The Bluetooth communication device is used due to highly reliable data transmission property and the Bluetooth chip is embedded in every mobile phone. The wearable shirts with chest belt of Bluetooth ECG module is designed with a focus on convenience in the daily life of a wearer. The ECG signal evaluation software in Android based mobile phone is developed for the health check and the ECG signal variation is tested according to the activities of the wearer such as walking, climbing stairs, stand up and sit down, and so on.

In Vitro Effects of Water and Methanol Extracts of Melittia inouei on Cytokine Production (유리나방 유충 추출물이 비장 세포로부터 Cytokine 분비에 미치는 효과)

  • Lee, Hyun-Ah;Shon, Hye-Jin;Yang, Young-Taek;Kim, Kyu-Don;Park, Hae-Cheol;Hwang, Jae-Sam;Hwang, Suk-Jo;Ahn, Mi-Young
    • Korean Journal of Pharmacognosy
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    • v.37 no.2 s.145
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    • pp.110-115
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    • 2006
  • Melittia inouei (Yuri Nabang) larvae are used as a crude drug in East Asia for treating stomach cancer and inflammation, and currently reared as a pharmaceutical insect in Jejudo, Korea. This study evaluated the immuno-modulating activity of these extracts, by determining the level of, cytokine production from mouse splenocytes stimulated with the extracts. The Melittia inouei larvae extracts did not induce the splenocyte proliferation. On the other hand, they stimulated the splenocytes to produce cytokines such as $TNF-{\alpha}$, whereas they did not stimulate IL10, IL12 or $IFN-{\gamma}$. The aqueous portion of its plant (Tri-chosanthis kirilowii) extract (sap) was found to be a potent inducer of NO production from the CPAE cells. However, it showed weak inhibitory effects on vascular endothelial growth factor (VEGF) production from splenocytes. These data suggests that a Melittia inouei larvae extract immune modulatory activity in cytokine prodcutions such as $TNF-{\alpha}$ and VEGF which might be related its anticancer effect.

New Finding and Optimal Production of a Novel Extracellular Alkaline Lipase from Yarrowia lipolytica NRRL Y-2178

  • Lee, Geon-Ho;Bae, Jae-Han;Suh, Min-Jung;Kim, In-Hwan;Hou, Ching T.;Kim, Hak-Ryul
    • Journal of Microbiology and Biotechnology
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    • v.17 no.6
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    • pp.1054-1057
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    • 2007
  • Lipases are industrially useful versatile enzymes that catalyze numerous different reactions including hydrolysis of triglycerides, transesterification, and chiral synthesis of esters under natural conditions. Although lipases from various sources have been widely used in industrial applications, such as in food, chemical, pharmaceutical, and detergent industries, there are still substantial current interests in developing new microbial lipases, specifically those functioning in abnormal conditions. We screened 17 lipase-producing yeast strains, which were prescreened for substrate specificity of lipase from more than 500 yeast strains from the Agricultural Research Service Culture Collection (Peoria, IL, U.S.A.), and selected Yarrowia lipolytica NRRL Y-2178 as a best lipase producer. This report presents new finding and optimal production of a novel extracellular alkaline lipase from Y. lipolytica NRRL Y-2178. Optimal culture conditions for lipase production by Y. lipolytica NRRL Y-2178 were 72 h incubation time, $27.5^{\circ}C$, pH 9.0. Glycerol and glucose were efficiently used as the most efficient carbon sources, and a combination of yeast extract and peptone was a good nitrogen source for lipase production by Y. lipolytica NRRL Y-2178. These results suggested that Y. lipolytica NRRL Y-2178 shows good industrial potential as a new alkaline lipase producer.

Survey of Pharmacy Practice for Compounding Parenteral Nutrition in Hospital Setting - 2009 (병원약국 대상으로 정맥영양제 조제 실행에 관한 연구-2009)

  • Sin, Hye-Yeon;Jung, Ki-Hwa
    • YAKHAK HOEJI
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    • v.54 no.4
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    • pp.244-251
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    • 2010
  • Standardized parenteral nutrition is required to improve patient's safety, clinical appropriateness and to increase uniformity between institution and institutions. We assessed the consistency with the American society for parenteral and enteral nutrition (A.S.P.E.N.) practice guideline for PN by evaluating current practice process for parenteral nutrition formulation in inpatients pharmacies in Korea. Each question in this survey was based on 2007 A.S.P.E.N. recommendations of standard parenteral nutrition formulation, the American society of health-system pharmacists (ASHP), and the United State Pharmacopoeia (USP) Chapter 797 guideline for compounding parenteral nutritions. All 90 Korean society of hospital pharmacist (KSHP) member directors of pharmacy were requested to respond to the survey in order to compare the survey results to ASHP national survey of pharmacy practice in hospital settings (2002) in compliance with A.S.P.E.N. guideline. We had final response rate of 35.6%. 25 (100%) hospitals complied with this Garb guideline (response rate was 84.4%) which was the highest compliance. Only 17.9% of hospital pharmacies were actively involved in complications monitoring. Monitoring complications and efficacy were least in compliance with the A.S.P.E.N. guideline. 69.0% of Korean pharmacists adjusted medication dosage based on disease state or monitoring laboratory data in compliance with the A.S.P.E.N. guideline. Over 50% of the hospital pharmacies failed to provide and evaluate staff training in aseptic manipulation skills periodically. Korean hospital pharmacies need to comply with the standard practice guideline for compounding sterile preparation in order to provide better quality of parenteral nutrition service for specific patient population.