• ETRI Journal
• /
• 제42권4호
• /
• pp.575-584
• /
• 2020

Electromagnetic (EM) waves used to send signals under seawater are normally restricted to low frequencies (f) because of sudden exponential increases of attenuation (𝛼) at higher f. The mathematics of EM wave propagation in seawater demonstrate dependence on relative permeability (𝜇_r), relative permittivity (𝜀_r), conductivity (𝜎), and f of transmission. Estimation of 𝜀_r and 𝜎 based on the W. Ellison interpolation model was performed for averaged real-time data of temperature (T) and salinity (S) from 1955 to 2012 for all oceans with 41 088 latitude/longitude points and 101 depth points up to 5500 m. Estimation of parameters such as real and imaginary parts of 𝜀_r, 𝜀_r', 𝜀_r", 𝜎, loss tangent (tan 𝛿), propagation velocity (V_p), phase constant (𝛽), and α contributes to absorption loss (L_a) for seawater channels carried out by using normal distribution fit in the 3 GHz-40 GHz f range. We also estimated total path loss (L_PL) in seawater for given transmission power P_t and antenna (dipole) gain. MATLAB is the simulation tool used for analysis.

• 조명전기설비학회논문지
• /
• 제21권10호
• /
• pp.59-65
• /
• 2007

최근 유비쿼터스 센서네트워크 기술이 전력설비관리에 적용되어 오고 있다. 본 연구에서는 가공배전선로에서 전력용변압기와 피뢰기를 관리할 수 있는 유비쿼터스 센서의 설계 및 제작에 대해 기술하였다. 이 센서들은 8-[bit] 마이크로프로세서, IEEE 802.15.4기반 무선통신모듈과 주변 전자회로로 구성되어 있다. 변압기의 부하 및 서지전류 측정에는 1000[A]까지 포화되지 않고 선형성을 유지할 수 있도록 공심형 로고우스키 코일을 제작하여 적용하였다. 피뢰기를 흐르는 $50[{\mu}A]{\sim}1[mA]$의 미소누설전류를 측정하기 위하여 180[Hz]에서 $10^5$의 고투자율을 갖는 영상변류기를 사용하였으며, 피뢰기 감시모듈의 -3[dB] 주파수 대역은 12[Hz]에서 1.24[kHz]이다.

• Macromolecular Research
• /
• 제16권1호
• /
• pp.15-20
• /
• 2008

The enhanced permeability and retention (EPR) effect is used extensively for the passive targeting of many macromolecular drugs for tumors. Indeed, the EPR concept has been a gold standard in polymeric anticancer drug delivery systems. This study investigated the tumoral distribution of self-assembled nanoparticles based on the EPR effect using fluorescein and radio-labeled nanoparticles. Self-assembled nanoparticles were prepared from amphiphilic chitosan derivatives, and their tissue distribution was examined in tumor-bearing mice. The size of the nanoparticles was controlled to be 330 run, which is a size suited for opening between the defective endothelial cells in tumors. The long-circulating polymer nanoparticles were allowed to gradually accumulate in the tumors for 11 days. The amount of nanoparticles accumulated in the tumors was remarkably augmented from 3.4%ID/g tissue at 1 day to 25.9%ID/g tissue at 11 days after i.v. administration. The self-assembled nanoparticles were sustained at a high level throughout the 14 day experimental period, indicating their long systemic retention in the blood circulation. The ${\gamma}$-images provided clear evidence of selective tumor localization of the $^{131}I$-labeled nanoparticles. Confocal microscopy revealed the fluorescein-labeled nanoparticles to be preferentially localized in the perivascular regions, suggesting their extravasation to the tumors through the hyperpermeable angiogenic tumor vasculature. This highly selective tumoral accumulation of nanoparticles was attributed to the leakiness of the blood vessels in the tumors and their long residence time in the blood circulation.

• 한국수자원학회논문집
• /
• 제33권5호
• /
• pp.611-622
• /
• 2000

본 연구에서는 제주도 서귀포유역의 지하수 유동시스템 해석을 위해 MODFLOW 모델을 이용하였으며 양수량 측정자료를 통한 투수량계수 및 저류계수를 초기치로 선정하여 시행착오법을 통한 대상유역의 최종 매개변수를 얻을 수 있었고 모델의 모의 발생을 한 결과 지하수유동시스템에 대한 적용성이 잘 반영됨을 알 수 있었다. 서귀포 유역은 지형지질을 고려한 관측치 해석, 이(1996)의 연구결과 및 모의발생을 통한 결과로 볼 때 지하수두 분포는 표고 400m이내에서 안정된 지하수 함양에 의한 용출이 이루어지고 있는 것으로 판단된다. 또한, 부정류상태하에서 지하수 유동경로 해석을 위하여 수두분포의 결과치를 이용한 유속벡터 분석을 실시한 결과 유속벡터가 상대적으로 크게 나타난 지역은 II, III 및 Ⅵ지점이었으며 지하수 유동경로는 I, II, III, IV, V, Ⅵ 및 Ⅶ지점의 각 방향으로 분산되어 유출되고 있음을 알 수 있었다.

• Journal of Ginseng Research
• /
• 제42권4호
• /
• pp.512-523
• /
• 2018

Background: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is required to improve its solubility and skin permeability, thereby enhancing its skin deposition. Thus, we optimized microemulsion (ME)-based hydrogel (MEH) formulations for the topical delivery of 20S-PPD. Methods: MEs and MEHs were formulated and evaluated for their particle size distribution, morphology, drug loading capacity, and stability. Then, the deposition profiles of the selected 20S-PPD-loaded MEH formulation were studied using a hairless mouse skin model and Strat-M membrane as an artificial skin model. Results: A Carbopol-based MEH system of 20S-PPD was successfully prepared with a mean droplet size of 110 nm and narrow size distribution. The formulation was stable for 56 d, and its viscosity was high enough for its topical application. It significantly enhanced the in vitro and in vivo skin deposition of 20S-PPD with no influence on its systemic absorption in hairless mice. Notably, it was found that the Strat-M membrane provided skin deposition data well correlated to those obtained from the in vitro and in vivo mouse skin studies on 20S-PPD (correlation coefficient $r^2=0.929-0.947$). Conclusion: The MEH formulation developed in this study could serve as an effective topical delivery system for poorly soluble ginsenosides and their deglycosylated metabolites, including 20S-PPD.

• 한국해양공학회지
• /
• 제30권6호
• /
• pp.505-519
• /
• 2016

If the seabed is exposed to high waves for a long period, the pore water pressure may be excessive, making the seabed subject to liquefaction. As the water pressure change due to wave action is transmitted to the pore water pressure of the seabed, a phase difference will occur because of the fluid resistance from water permeability. Thus, the effective stress of the seabed will be decreased. If a composite breakwater or other structure with large wave reflection is installed over the seabed, a partial standing wave field is formed, and thus larger wave loading is directly transmitted to the seabed, which considerably influences its stability. To analyze the 3-D dynamic response characteristics of the seabed around a composite breakwater, this study performed a numerical simulation by applying LES-WASS-3D to directly analyze the wave-structure-soil interaction. First, the waveform around the composite breakwater and the pore water pressure in the seabed and rubble mound were compared and verified using the results of existing experiments. In addition, the characteristics of the wave field were analyzed around the composite breakwater, where there was an opening under different incident wave conditions. To analyze the effect of the changed wave field on the 3-D dynamic response of the seabed, the correlation between the wave height distribution and pore water pressure distribution of the seabed was investigated. Finally, the numerical results for the perpendicular phase difference of the pore water pressure were aggregated to understand the characteristics of the 3-D dynamic response of the seabed around the composite breakwater in relation to the water-structure-soil interaction.

• 한국철도학회논문집
• /
• 제17권3호
• /
• pp.186-192
• /
• 2014

본 연구에서는 콘크리트 진공튜브 구조의 설계에 있어서 주어진 재료 및 시스템 구성에서 존재하는 불확실성을 정량화하여 내부기압의 변화를 확률적으로 예측할 수 있는 신뢰성 평가를 수행하였다. 시스템 등가투기계수의 산정 및 외부기압에 영향을 주는 인자들 중 불확실성을 내재하고 있는 인자들을 확률변수로 모델링한 후 수식 유도 및 시뮬레이션을 통해 시간에 따른 내부기압의 변화를 확률적으로 예측하였으며 확정적 해석과 그 결과를 비교 분석한 결과 적정 수준의 신뢰성을 얻기 위해서는 단면의 변화가 반드시 필요한 것으로 나타났다. 이와 같은 튜브구조의 기밀성능에 대한 확률적 해석 결과는 튜브 내부를 주행하는 열차 또는 다른 운송수단의 추진력과 공기저항, 그리고 펌프의 용량을 복합적으로 고려하여 목표 압력을 정하고 튜브 단면을 결정하는데 필요한 기술적 자료로써 활용될 수 있을 것이다.

• 한국신재생에너지학회:학술대회논문집
• /
• 한국신재생에너지학회 2010년도 추계학술대회 초록집
• /
• pp.76.1-76.1
• /
• 2010

Recently, many efforts to solve the durability problem of PEM fuel cell are carried on constantly. However, despite this attention, durability researches of gas diffusion layer (GDL) are not much reported yet. Generally, GDL of PEM fuel cell experiences three external attacks, which are dissolution of water, erosion of gas flow, corrosion of electric potential. In this study, among these degradation factors, carbon corrosion of electric potential was focused and investigated with accelerated carbon corrosion test. Through the test, it is confirmed that carbon corrosion occurred at GDL, and corroded GDL decreased a performance of operating fuel cell. The property changes of GDL were measured with various methods such as air permeability meter, pore distribution analyzer, thermo gravimetric analyzer, and tensile stress test to discover the effects of carbon corrosion. Carbon corrosion caused not only loss of weight and thickness, but also degradation of mechanical strength of GDL. In addition, to analysis the reason of GDL property changes, a surface and a cross section of GDL were observed with scanning electron microscope. After 100 hours test, the GDL showed serious damage in center of layer.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2001년도 춘계학술대회논문집D
• /
• pp.365-370
• /
• 2001

There are various wick types for heat pipe. In the present study, the manufacturing technology of a sintered wick among various wick types is discussed. The sintering technology using metal has been applied broadly in the field of electronic-telecommunication as well as heat pipes. A study of manufacturing procedure and characteristic of sintered wick for heat pipe have been performed. Copper powder was used as wick material and stainless steel as a mandrel. A manufacturing technology of the mandrel for arranging vapor core in heat pipe, a sintering technology by first or second times and operating temperature for sintering, the measurements of a porosity, pore size, and pore distribution of sintered wick were considered. In the meantime, a heat pipe with sintered wick has been manufactured and a performance test of the heat pipe has been performed in order to review cooling performance. The performance test results for the 4mm diameter heat pipe with the sintered wick shows the stability since the temperature difference between a evaporator and a condenser of the heat pipe is less than $4.4^{\circ}C$, and thermal resistance is less than $0.7^{\circ}C/W$.

• 지질공학
• /
• 제3권2호
• /
• pp.203-214
• /
• 1993

액체 산업폐기물을 심층지하에 방출시, 폐기물의 이동은 지하매체의 낮은 투수율로 인하여 분자확산에 의해 좌우된다. 하편 확산에 의한 이동은 Fick의 제2법칙으로 예측할 수 있다. 본 연구에서는 실험을 통한 Cr(VI)의 확산 이동계수를 구하였다. 다공질내에서의 Cr(VI)이동을 추적하기 위해 방사성 동위원소인 $^{51}Cr$을 사용하였으며, Fick의 제2법칙에 대한 해석해를 구해 Cr(VI)의 확산계수를 결정하였다. 본 연구에서는 온도, $^{51}Cr$의 양, 염소 이온의 양, 매체의 건조밀도를 환경적 변화인자로 이용하였다.