• The Journal of Engineering Geology
• /
• v.19 no.4
• /
• pp.493-499
• /
• 2009

Recently, the construction of Concrete Faced Rockfill Dam (CFRD) is increasing because rock material resources are plenty in Korea. Bedding zone in the CFRD is necessary enough bearing capacity to support the concrete face slab uniformly and enough impermeability to prevent the loss of fine soils in case of leakage from the concrete slab face. Therefore, cut-off the water leakage in bedding zone securely is the key factor influencing the safety of CFRD. Tested materials satisfied with the specification of particle size distribution at the Bedding Zone area are chosen for conducting permeability tests, which are done to evaluate the property of cut off the materials. Based on the test results, the effects of cut off the materials are investigated by considering the coefficient of permeability, the soil particle distribution, and the dry unit weight. Especially, the relationships between coefficient of permeability with effective size(D10), dry unit weight, and weight passing percent the No.4 sieve are suggested, and also the variation of coefficient of permeability with time are proposed.

• Reproductive and Developmental Biology
• /
• v.34 no.3
• /
• pp.153-159
• /
• 2010

The 34 potently pig pheromonal odorants (1-32, 5755 & 7113) through structure-based virtual screening and ligand-based virtual screening method were selected and their ADMET and pharmacokinetics characters were evaluated and discussed quantitatively. The pheromonal odorants were projected on the following pre-calculated models, Caco-2 cell permeability, blood-brain barrier permeation, hERG inhibition and volume-distribution. From the results of in silico study, it is found that an optimal compound (31) either penetrating or have a little ($P_{caco2}$=-8.143) for Caco-2 cell permeability, moderate penetrating ability ($P_{BBB}$=0.082) for blood-brain barrier permeation, the low QT prolongation ($P_{hERG}$=1.137) for the hERG $K^+$ channel inhibition, and low distribution into tissues ($P_{VD}$=-5.468) for volume-distribution. Therefore, it is predicted that the compound (31) a topical application may be preferable from these based foundings.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.48 no.6
• /
• pp.59-67
• /
• 2006

Particles of soil are crushed when soil is compacted in the in-situ or lab. Among many factors that affect the crush of particles, compaction energy is a major factor. Because the crush of particles can change physical properties, the analysis of effect of compaction energy is very important. In this study, the fragmentation fractals were used for determining the change in grain size distribution and the effect due to change in grain size distribution was estimated. Compaction energy was increased by 50, 100, 200 and 300% based on the energy of standard A compaction test. As a result, grain size distribution curves were changed and fine particles increased as compaction energy were increased. Relative compaction were ranged between $93.38{\sim}107.67$. Fractal dimension of each site increased as compaction energy increased. Relative compaction is proportional to the fractal dimension but coefficients of permeability were in inverse proportional to the involution of fractal dimension.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.15 no.3
• /
• pp.333-344
• /
• 2013

This paper discussed about the effect of permeability reduction of the jointed rock mass in the vicinity of a tunnel which is one of the reasons making large difference between the estimated ground-water inflow rate and the measured value. Current practice assumes that the jointed rock mass around a tunnel is a homogeneous, isotropic porous medium with constant permeability. However, in actual condition the permeability of a jointed rock mass varies with the change of effective stress condition around a tunnel, and in turn effective stress condition is affected by the ground water flow in the jointed rock mass around the tunnel. In short time after tunnel excavation, large increase of effective tangential stress around a tunnel due to stress concentration and pore-water pressure drop, and consequently large joint closure followed by significant permeability reduction of jointed rock mass in the vicinity of a tunnel takes place. A significant pore-water pressure drop takes place across this ring zone in the vicinity of a tunnel, and the actual pore-water pressure distribution around a tunnel shows large difference from the value estimated by an analytical solution assuming the jointed rock mass around the tunnel as a homogeneous, isotropic medium. This paper presents the analytical solution estimating pore-water pressure distribution and ground-water inflow rate into a tunnel based on the concept of hydro-mechanically coupled behavior of a jointed rock mass and the solution is verified by numerical analysis.

• Investigative Magnetic Resonance Imaging
• /
• v.2 no.1
• /
• pp.73-82
• /
• 1998

Purpose : A precise NMR technique for measuring the rate of water exchange and cell membrane permeability across the hepatocyte membrane using liver-specific MR contrast agent is described. Materials and Methods : The rat hepatocytes isolated by perfusion of the livers were used for the NMR measurements. All experiments were performed on an IBM field cycling relaxometer operating from 0.02MHz to 60 MHz proton Larmor frequency. spin-echo pulse sequence was empolyed to measure spin-lattice relaxation time, T1. The continuous distribution analysis of water proton T1 data from rat hepatocytes containing low concentrations of the liver specific contrast agent, Gd-EOB-DTPA, modeled by a general two compartment exchange model. Results : The mean residence time of water molecule inside the hepatocyte was approximately 250 msec. The lower limit for the permeability of the hepatocyte membrane was $(1.3{\pm}0.1){\;}{\times}{\;}10^{-3}cm/sec$. The CONTIN analysis, which seeks the natural distribution of relaxation times, reveals direct evidence of the effect of diffusive exchange. the diffusive water exchange is not small in the intracellular space in the case of hepatocytes. Conclusions : Gd-EOB-DTPA, when combined with continuous distribution analysis, provides a robust method to study water exchange and membrane permeability in hepatocytes. Water exchange in hepatocyte is much slower thatn that in red blood cells. Therefore, tissue-specific contrast agent may be used as a functional agent to give physiological information such as cell membrane permeability.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.36 no.2
• /
• pp.207-217
• /
• 2016

Permeability can not be expressed as a function of porosity alone, it depends on the porosity, pore size and distribution, and tortuosity of pore channels in concrete. There has been considerable interest in the relationship between microstructure and transport in cementitious materials, however, it is very rare to deal with the theoretical study on gas permeability coefficient in connection with carbonation of concrete and the effect of volumetric fraction of cement paste or aggregate on the permeability coefficient. The majority of these researches have not dealt with this issue combined with carbonation of concrete, although carbonation can significantly impact on the permeability coefficient of concrete. In this study, fundamental approach to compute gas permeability of (non)carbonated concrete is suggested. For several compositions of cement pastes, the gas permeability coefficient was calculated with the analytical formulation, followed by a microstructure-based model. For carbonated concrete, reduced porosity was calculated and this was used for calculating the gas permeability coefficeint. As the result of calculation of gas permeability for carbonated concrete, carbonation leaded to the significant reduction of gas permeability coefficient and this was obvious for concrete with high w/c ratio. Meanwhile, the relationship between gas permeability and water permeability has a linear function for cement paste based on Klinkenberg effect, however, which is not effective for concrete. For the evidence of the modeling, YOON's test was accomplished and these results were compared to each other.

• The Journal of Engineering Geology
• /
• v.17 no.1 s.50
• /
• pp.135-142
• /
• 2007

Although rock itself has high strength or low permeability, engineering properties of rock masses are significantly influenced by discontinuities such as cracks and joints. Considered with possibility of groundwater flow in massive rock mass of deep subsurface, the connectivity of micro cracks should be analyzed as a conduit of ground-water flow. The objective of this study is to estimate permeability characteristics of granite dependent on damage process with application of joint distribution analysis and modeling of permeability analysis in rock masses. In case of average permeability coefficients, the modeling results based on micro cracks data are well matched with the results from permeability tests. Based on the visualization result of three dimensional model, the average permeability coefficients through the discharge plane have a positive relationship with the number of microcrack induced by rock damage.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.13 no.3
• /
• pp.1391-1395
• /
• 2012

In order to find out the influences of the coefficient of permeability and the coefficient of consolidation on the consolidation of nonhomogeneous soils, self-developed program was used. For the purpose of analysis, nonhomogeneous soils of two layers which have various values of coefficient of permeability and coefficient of consolidation were assumed and analyzed by the developed program. According to the results obtained by the analysis, coefficient of consolidation has great effect on the distribution of excess pore water pressure and the consolidation settlement whereas coefficient of permeability has little effect on the characteristics of consolidation of nonhomogeneous soils.

• Geomechanics and Engineering
• /
• v.7 no.6
• /
• pp.649-663
• /
• 2014

In past few years, the use of bacterial calcium carbonate precipitation (biocementation) has become popular as a ground improvement technique for sandy soil. However, this technique was not applied to organic soil. This study focused on bacterial calcium carbonate precipitation and its effect on permeability in organic soil. A special injection system was prepared for inducing bacterial solution to the samples. The bacterial solution supplied to the samples by gravity for 4 days in specific molds designed for this work. Calcite precipitation was observed by monitoring pH value and measuring amount of calcium carbonate. Change in the permeability was measured before and after biocementation. The test results showed that the pH values indicates that the treatment medium is appropriate for calcite precipitation, and amount of precipitated calcium carbonate in organic soil increased about 20% from untreated one. It was also found that the biocementation can be considered as an effective method for reducing permeability of organic soil. The results were supported by Scanning electron microscopy (SEM) analysis and energy-dispersive x-ray (EDX) analysis.

• International Journal of Concrete Structures and Materials
• /
• v.19 no.1E
• /
• pp.41-48
• /
• 2007

Addition of latex to concrete is known to increase its durability and permeability. The purpose of this study is to analyze air void systems in latex-modified concretes using a reasonable and objective method of image analysis with such experimental variables as water-cement (w/c) ratios, latex contents (0%, 15%) and cement types (ordinary portland cement (OPC), high-early strength (HES) cement and very-early strength (VES) cement). The results are analyzed by spacing factor, air volume (content) after hardening, air void distribution and structure. Additionally, air void systems and permeability of latex-modified concrete (LMC) are compared by a correlation analysis. The results are as follows. The LMC of the same w/c ratio showed better air entraining (AE) effect than OPC with AE water reducer. The VES-LMC showed that the quantity of entrained air below $100{\mu}m$ increased more than four times. For the case of HES-LMC, microscopic entrained air between the range of 50 to $500{\mu}m$ increased greater than 7 times even in the absence of anti-foamer. Although spacing factor was measured rather low, the permeability of latex-modified concrete was good. It is construed that air void system does not have a considerable effect on the property of latex-modified concrete, but latex film (membrane) has a definite influence on the durability of LMC.