• Title/Summary/Keyword: performance design

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Study Design and Baseline Results in a Cohort Study to Identify Predictors for the Clinical Progression to Mild Cognitive Impairment or Dementia From Subjective Cognitive Decline (CoSCo) Study

  • SeongHee Ho;Yun Jeong Hong;Jee Hyang Jeong;Kee Hyung Park;SangYun Kim;Min Jeong Wang;Seong Hye Choi;SeungHyun Han;Dong Won Yang
    • Dementia and Neurocognitive Disorders
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    • v.21 no.4
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    • pp.147-161
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    • 2022
  • Background and Purpose: Subjective cognitive decline (SCD) refers to the self-perception of cognitive decline with normal performance on objective neuropsychological tests. SCD, which is the first help-seeking stage and the last stage before the clinical disease stage, can be considered to be the most appropriate time for prevention and treatment. This study aimed to compare characteristics between the amyloid positive and amyloid negative groups of SCD patients. Methods: A cohort study to identify predictors for the clinical progression to mild cognitive impairment (MCI) or dementia from subjective cognitive decline (CoSCo) study is a multicenter, prospective observational study conducted in the Republic of Korea. In total, 120 people aged 60 years or above who presented with a complaint of persistent cognitive decline were selected, and various risk factors were measured among these participants. Continuous variables were analyzed using the Wilcoxon rank-sum test, and categorical variables were analyzed using the χ2 test or Fisher's exact test. Logistic regression models were used to assess the predictors of amyloid positivity. Results: The multivariate logistic regression model indicated that amyloid positivity on PET was related to a lack of hypertension, atrophy of the left temporal lateral and entorhinal cortex, low body mass index, low waist circumference, less body and visceral fat, fast gait speed, and the presence of the apolipoprotein E ε4 allele in amnestic SCD patients. Conclusions: The CoSCo study is still in progress, and the authors aim to identify the risk factors that are related to the progression of MCI or dementia in amnestic SCD patients through a two-year follow-up longitudinal study.

A Study on Precision Positioning Methods for Autonomous Mobile Robots Using VRS Network-RTK GNSS Module (VRS 네트워크-RTK GNSS 모듈을 이용한 자율 이동 로봇의 정밀 측위방법에 관한 연구)

  • Dong Eon Kim;YUN-JAE CHOUNG;Dong Seog Han
    • Journal of the Korean Association of Geographic Information Studies
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    • v.27 no.3
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    • pp.1-13
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    • 2024
  • This paper proposes a cost-effective system design and user-friendly approach for the key technological elements necessary to configure an autonomous mobile robot. To implement a high-precision positioning system using an autonomous mobile robot, we established a Linux-based VRS (virtual reference station)-RTK (real-time kinematic) GNSS (global navigation satellite system) system with NTRIP (Network Transport of RTCM via Internet Protocol) client functionality. Notably, we reduced the construction cost of the GNSS positioning system by performing dynamic location analysis of the established system, without utilizing an RTK replay system. Dynamic location analysis involves sampling each point during the trajectory following of the autonomous mobile robot and comparing the location precision with ground-truth points. The proposed system ensures high positioning performance with fast sampling times and suggests a GPS waypoint system for user convenience. The centimeter-level precision GNSS information is provided at a 30Hz sampling rate, and the dead reckoning function ensures valid information even when passing through tall buildings and dense forests. The horizontal position error measured through the proposed system is 6.7cm, demonstrating a highly precise dynamic location measurement error within 10cm. The VRS network-RTK Linux system, which provides precise dynamic location information at a high sampling rate, supports a GPS waypoint planner function for user convenience, enabling easy destination setting based on GPS information.

Validation of Launch Vibration Isolation Performance of the Passive Vibration Isolator for the Scientific Payload BioCabinet for CAS500-3 (차세대중형위성 3호 과학탑재체 바이오캐비넷용 수동형 진동절연기의 발사진동 저감성능 검증)

  • Dong-Jae Seo;Yeon-Hyeok Park;Young-Jin Lee;Ji-Seung Lee;Kyung-Hee Kim;Soon-Hee Kim;Chan-Hum Park;Hyun-Ung Oh
    • Journal of Aerospace System Engineering
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    • v.18 no.4
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    • pp.81-88
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    • 2024
  • The payload BioCabinet of CAS500-3 is designed for 3D stem cell differentiation, culture, and analysis utilizing bio 3D printing techniques in space. The 3D printing technique was initially developed for orbital use; however, it lacks separate validation for extreme launch vibration environments, necessitating a design that mitigates the launch load on the payload. This paper proposes a passive vibration isolator with a low-stiffness elastic support structure and high damping characteristics to reduce the launch loads affecting the BioCabinet. We explore the high-damping characteristics through the superelastic effects of SMA (Shape Memory Alloys) and a multi-layered structure incorporating viscoelastic tape. The effectiveness of the proposed vibration isolation system was confirmed via launch vibration tests on a qualification model.

Literature Review of Model Testing Techniques for Performance Evaluation of Floating Offshore Wind Turbine in Ocean Basin (부유식 해상풍력 시스템 성능평가를 위한 수조모형시험 기법고찰)

  • Yoon-Jin Ha;Hyeonjeong Ahn;Sewan Park;Ji-Yong Park;Dong Woo Jung;Jae-Sang Jung;Young Uk Won;Ikseung Han;Kyong-Hwan Kim;Jonghun Lee
    • Journal of Wind Energy
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    • v.13 no.4
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    • pp.26-41
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    • 2022
  • Three similarities (i.e., geometrical similarity, kinematic similarity and dynamic similarity) between a prototype and model must be satisfied to perform an experiment for a floating offshore wind turbine (FOWT). For dynamic similarity, most of the model tests in ocean engineering basins are performed based on the Froude number, so the scale effect for the wind turbine of an FOWT occurs by different Reynolds numbers between the prototype and model. In this study, various model test techniques for overcoming the scale effect of the wind turbine part of the FOWT are investigated. Firstly, model test techniques using simple approaches are reviewed, and the advantages and disadvantages of the simple approaches are summarized. Secondly, the model test techniques in recent projects that apply improved approaches are introduced including advantages and disadvantages. Finally, new approaches applying digitalization are reviewed, and the characteristics of the new approaches are introduced.

Effect of Dietary Bacillus subtilis on Growth Performance, Immunological Cells Change, Fecal NH3-N Concentration and Carcass Meat Quality Characteristics in Finishing Pigs (비육돈 사료내 Bacillus subtilis의 첨가가 성장, 면역세포 변화, 분내 암모니아태질소 함량 및 도체 특성에 미치는 영향)

  • Cho, J.H.;Chen, Y.J.;Min, B.J.;Kim, H.J.;Shon, K.S.;Kwon, O.S.;Kim, J.D.;Kim, I.H.
    • Journal of Animal Science and Technology
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    • v.47 no.6
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    • pp.937-946
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    • 2005
  • This experiment was conducted to investigate the effects of dietary Bacillus subtilis on growth performance, nutrient digestibility, immunological cells change, fecal noxious gas and carcass meat quality characteristics in finishing pigs. The dietary treatments were 1) CON(basal diet), 2) BS0.1(basal diet+ 0.1% Bacillus subtilis) and 3)BS0.2(basal diet+0.2% Bacillus subtilis). Sixty crossbred(Landrace$\time$ Yorkshire$\time$Duroc) pigs(89.5$\pm$0.11kg average initial body weight) were used in a 42 days growth trial. The pigs were assigned to the treatments according to body weight and each treatment had 5 replicates of 4 pigs per pen in a randomized complete block design. Through the entire experimental period, average daily gain(ADG) and average daily feed intake(ADFI) were not significantly different among the treatments. Pigs fed BS0.1 diet significantly increased their gain/feed compared to pigs fed CON and BS0.2 diets(P<0.05). Also, dry matter(DM) and nitrogen(N) digestibilities were greater in the pigs fed BS0.1 diet than those fed CON diet(P<0.05). There were no significant differences in fecal NH3-N concentration among the treatments. In blood assay for immunological cells change investigations, red blood cells(RBC) counts increased in the pigs fed BS0.2 diet compared to pigs fed CON and BS0.1 diets. There were no significant differences in carcass pH, drip loss, marbling and firmness. However, sensual color and a*(redness) value of meat in the pigs fed BS0.2 diet were higher than in pigs fed CON diet(P<0.05). Therefore, this experiment suggested that Bacillus subtilis supplementation could improve nutrient digestibility, RBC counts and carcass meat color of pigs.

Cyclic Seismic Performance of RBS Weak-Axis Welded Moment Connections (RBS 약축 용접모멘트접합부의 내진성능 평가)

  • Lee, Cheol Ho;Jung, Jong Hyun;Kim, Sung Yong
    • Journal of Korean Society of Steel Construction
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    • v.27 no.6
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    • pp.513-523
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    • 2015
  • In steel moment frames constructed of H-shapes, strong-axis moment connections should be used for maximum structural efficiency if possible. And most of cyclic seismic testing, domestic and international, has been conducted for strong-axis moment connections and cyclic test data for weak-axis connections is quite limited. However, when perpendicular moment frames meet, weak-axis moment connections are also needed at the intersecting locations. Especially, both strong- and weak-axis moment connections have been frequently used in domestic practice. In this study, cyclic seismic performance of RBS (reduced beam section) weak-axis welded moment connections was experimentally investigated. Test specimens, designed according to the procedure proposed by Gilton and Uang (2002), performed well and developed an excellent plastic rotation capacity of 0.03 rad or higher, although a simplified sizing procedure for attaching the beam web to the shear plate in the form of C-shaped fillet weld was used. The test results of this study showed that the sharp corner of C-shaped fillet weld tends to be the origin of crack propagation due to stress concentration there and needs to be trimmed for the better weld shape. Different from strong-axis moment connections, due to the presence of weld access hole, a kind of CJP butt joint is formed between the beam flange and the horizontal continuity plate in weak-axis moment connections. When weld access hole is large, this butt joint can experience cyclic local buckling and subsequent low cycle fatigue fracture as observed in this testing program. Thus the size of web access hole at the butt joint should be minimized if possible. The recommended seismic detailing such as stickout, trimming, and thicker continuity plate for construction tolerance should be followed for design and fabrication of weak-axis welded moment connections.

Studies on Working Intensity in Felling Operation of the Thinning Forest -In Thinning of Some Conifer Species- (벌채작업(伐採作業)에서의 작업강도(作業强度) 측정연구(測定硏究) -침엽수(針葉樹) 간벌림에(間伐林)서-)

  • Park, Soo-Kyoo;Kang, Gun-Uh
    • Journal of Korean Society of Forest Science
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    • v.85 no.3
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    • pp.396-408
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    • 1996
  • The purposes of this study were to standardise the forest working system to design the intensity of working system in felling operation of the thinning forest in our country as well as to contrive the improvement of working method and the increase of productivity. For the purpose of investigating these, element working was classified by felling operation in softwood thinning forest, and a pulse rate were measured and analyzed. The results were as follow : 1. From the analysis of the pulse frequence measurment, the average pulse showed 108 pulse per minute for worker A in the total of pure working time, 130 pulse per minutes for worker B, 119 pulse per minute for worker C and 125 pulse per minute for worker D, respectively. 2. From the results of the pulse frequence analysis according to element working classification, the highest pulse frequence represented 115 pulse per minute for worker A in the circumference, 131 pulse per minute for worker B in the movement, 122 pulse per minute for worker C in the limbing operation and 128 pulse per minute for work D in hang-up. 3. If the original pulse frequence was 100% for workers, the working intensity showed as follow : worker A was 160%(original pulse frequence was 61=100%) for the total of the working intensity and 188% for the circumference among element working. Worker B was 220%(original pulse frequence was 57=100%) for the total of the working intensity and 229 for movement among element working. Worker C was 159%(original pulse frequence was 73=100%) for the total of the working intensity and 168% for limbing operation among the element working. Worker D was 156%(original pulse frequence was 70=100%) for the total of working intensity and 182% for hang-up among element working. 4. At the limit point of Labor performance rating, showing the total of working intensity, overtime pulse rate per minute was 30 for worker A, 207 for worker B, 14 for worker C and 67 for worker D. Worker B was highest in working intensity, and got physically a big load.

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Effects of Total Mixed Rations with Corn on Growth and Meat Quality of Castrated Korean Black Goats (옥수수 첨가 TMR 사료 급여가 거세흑염소의 발육과 육질에 미치는 영향)

  • Kim, Sang-Uk;Choi, Young-Sun;Yoo, Dae-Joong;Ku, Min-Jung;Lee, Gi-Ho;Park, Sang-Guk
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.4
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    • pp.350-356
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    • 2016
  • The objective of this study was to evaluate the effect of different dietary corn levels in Total Mixed Rations (TMR) on growth and meat quality of castrated Korean black goats. For feeding trials, thirty-two castrated Korean black goats with similar age (average of 3 months) and body weight (average of 15.9 kg) were divided into the following four treatment groups: commercial feed (control), TMR containing 15% of corn (T1), TMR containing 25% of corn (T2), and TMR containing 35% of corn (T3) in a randomized complete block design. Final body weight was the highest in T2 (58.9 kg), followed by that in control group (53.1 kg). Average daily gain (ADG) and total dry matter intake (TDMI) were also the highest in T2 (100.2 g and 1,346 g, respectively). However, feed conversion ratio (13.4) was the lowest in T2. Carcass weight and dressing percentage in T2 and T3 were higher than those in the control. For meat quality characteristics, crude fat content was the highest in T2 (6.54%). Cooking loss (15.2%) was the lowest in the control. However, the control had the highest flavor value (5.3%). Oleic acid (C18:l) and palmitic acid (C16:0) were the highest in T2 (48.6% and 22.4%, respectively). Stearic acid (C18:0) was the highest in T1 (14.5%). Unsaturated fatty acid was the highest in the control (58.8%), followed by that in T3 (58.2%), T2 (57.8%), and T1 (54.4%). These results indicate that TMR containing 25% of corn could improve the growth performance and meat quality of castrated Korean black goats.

Stud and Puzzle-Strip Shear Connector for Composite Beam of UHPC Deck and Inverted-T Steel Girder (초고성능 콘크리트 바닥판과 역T형 강거더의 합성보를 위한 스터드 및 퍼즐스트립 전단연결재에 관한 연구)

  • Lee, Kyoung-Chan;Joh, Changbin;Choi, Eun-Suk;Kim, Jee-Sang
    • Journal of the Korea Concrete Institute
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    • v.26 no.2
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    • pp.151-157
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    • 2014
  • Since recently developed Ultra-High-Performance-Concrete (UHPC) provides very high strength, stiffness, and durability, many studies have been made on the application of the UHPC to bridge decks. Due to high strength and stiffness of UHPC bridge deck, the structural contribution of top flange of steel girder composite to UHPC deck would be much lower than that of conventional concrete deck. At this point of view, this study proposes a inverted-T shaped steel girder composite to UHPC deck. This girder requires a new type of shear connector because conventional shear connectors are welded on top flange. This study also proposes three different types of shear connectors, and evaluate their ultimate strength via push-out static test. The first one is a stud shear connector welded directly to the web of the girder in the transverse direction. The second one is a puzzle-strip type shear connector developed by the European Commission, and the last one is the combination of the stud and the puzzle-strip shear connectors. Experimental results showed that the ultimate strength of the transverse stud was 26% larger than that given in the AASHTO LRFD Bridge Design Specifications, but a splitting crack observed in the UHPC deck was so severe that another measure needs to be developed to prevent the splitting crack. The ultimate strength of the puzzle-strip specimen was 40% larger than that evaluated by the equation of European Commission. The specimens combined with stud and puzzle-strip shear connectors provided less strength than arithmetical sum of those. Based on the experimental observations, there appears to be no advantage of combining transverse stud and puzzle-strip shear connectors.

Effects of Concentrate Feeding Method and Slaughter Age on Growth Performance, Feed Intake and Carcass Characteristics of Hanwoo Steers (거세한우 배합사료 급여방법 및 출하월령이 발육, 사료섭취량 및 도체특성에 미치는 영향)

  • Cho, Young-Moo;Chang, Sun-Sik;Kim, Hyeong-Cheol;Kim, Tae-Il;Park, Byung-Ki;Paek, Bong-Hyun;Kim, Jin-Hyoung;Kwon, Eung-Gi
    • Journal of Animal Science and Technology
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    • v.51 no.1
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    • pp.53-60
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    • 2009
  • Thirty one Hanwoo steers were used in a completely randomized design experiment to see the effects of concentrate feeding method (group vs. individual feeding) and age at slaughter (26 vs. 28 months of age) on growth performance, feed intake and carcass characteristics. Steers were randomly assigned to one of four groups, G26 (group feeding slaughtered at 26 months of age), G28 (group feeding slaughtered at 28 months of age), I26 (individual feeding slaughtered at 26 months of age) or I28 (individual feeding slaughtered at 28 months of age). Amount of concentrate were restricted to 1.5% of BW for the growing period and 1.8% of BW for the early fattening period in both groups. For the late fattening period, concentrate were given ad libitum for G26 and G28, but were given up to 1.7% of BW for I26 and I28. Average daily gains were higher in individual feeding groups (I26 and I28) than those in group feeding groups (G26 and G28) for the early fattening period (p<0.05). ADGs were higher in group feeding groups than those in individual feeding groups (p<0.05). Concentrate intake in individual feeding groups tended to be higher compared to that in group feeding groups for the early fattening period, but tended to be higher in group feeding groups compared to that in individual feeding groups for the late fattening period. Feeding method or slaughter age had no significant effects on carcass characteristics, yield grade and quality grade. Shear force and tenderness of longissmus muscle were higher in groups slaughtered at 28 months of age than in groups slaughtered at 26 months of age (p<0.05). Feeding method or slaughter age had no effects on cooking loss, water holding capacity, juiciness, flavor, moisture, protein and fat of longissmus muscle.