• Journal of Chest Surgery
• /
• v.17 no.4
• /
• pp.593-606
• /
• 1984

With the ligation of patent ductus arteriosus by Gross in 1938, surgeons first entered the field of congenital heart disease. Interruption of a ductus is one of the most satisfactory and curative operations in the field of surgery for congenital heart disease. 27 cases of isolated patent ductus arteriosus were operated from Jan. 1978 to July 1984 at the Department of Thoracic & Cardiovascular Surgery in Kyung-Hee University Hospital. Retrospective clinical analysis of these patients were: 1. Sex ratio, female: male, was 2:1. 2. Mean age at operation was 9.85\ulcorner.58 years. The youngest patient was a 23 month-old girl and the oldest one was a 24 year-old male. 3. More than half of the patients had less than 50 percentile of growth retardation. 4. Chief complaints of the patients were frequent URI [52%], dyspnea on exertion [33%], generalized weakness [22%], palpitation [7%], but 7 patients [26%] had no subjective symptoms. 5. Continuous machinery murmur could be heard at the 2nd or 3rd intercostal space on the left sternal border in 22 patients [81%]. The other S patients made systolic murmur with accentuation of the second heart sound and those were associated with pulmonary hypertension. 6. Radiologic findings of Chest P-A were cardiac enlargement in 15 patients [55%], enlargement of pulmonary conus and/or increasing density of pulmonary vascularity in 20 patients [74%]. 7. Electrocardiographic findings of the patients were within normal limit in 13 patients [48%], LVH in 4 patients [15%], biventricular hypertrophy in 3 patients [11%]. 8; echocardiogram was obtained from 11 patients. Ductus was directly visualized in 7 patients. Left atrial enlargement is the secondary change of left to right shunt, 10 patients had LA/Ao ratio more than 1.2. 9. Cardiac catheterization performed in 25 patients. The mean value of the results were:SO2[PA-RV]= 14.72\ulcorner6.01%, Qp/Qs=2.22\ulcorner.80, peak systolic pulmonary arterial pressure=48.28\ulcorner1.60 mmHg. 10. 26 patients were operated through the left posterolateral thoracotomy: closure of ductus by double ligation in 14 cases, triple ligation in 5 cases, and division with suture in 8 cases. One patient suffer from aneurysmal rupture of main pulmonary artery, endocarditis, hemopericardium was treated with cardiopulmonary bypass via median sternotomy and closure of ductus through the ruptured main pulmonary artery. 11.There was no death associated with the operation, but 3 cases were experienced with intraoperative rupture around the ductus resulting in massive bleeding. The other complications were transient hoarseness in one patient, atelectasis in left lower lobe in 3 patients, and postoperative systemic hypertension in 4 patients with unknown etiology. 12. Pulse pressure was reduced, 11.47+5.92 mmHg, postoperatively, as compare to preoperative status. 13. Intraoperative wedge lung biopsy from lingular segment for the evaluation of the pulmonary vascular disease was taken in S patients with severe pulmonary hypertension. The result was Heath-Edward grade I in one case, grade II in two cases, and grade III in two cases.

• Korean Journal of Community Nutrition
• /
• v.1 no.1
• /
• pp.61-70
• /
• 1996

Correlations of adolescents' blood pressure with dietary factors and blood or urinary electrolytes were investigated in this study. Through the screening for blood pressures of 960 middle school students aged 13-16 years, 30 students with the mean value of SBP and DBP above 96th percentile(high blood pressure group) and the other 30 with the mean blood pressure between 48th and 52th percentiles(normal blood pressure group) were selected as the subjects. SBP/DBP of the high and talc normal blood pressure groups were $141.8{\pm}9.0$ / $83.6{\pm}5.1$ mmHg and $116.4{\pm}3.5$ / $69.8{\pm}3.7 mmHg$, respectively. The average values of age, weight, height, BMI, degree of relative crude physical activity, and family income were not different between two groups. Among nutrients for which intakes were determined by 24 hour-recall and expressed as percent RDA, intakes of total and animal calcium were lower in the high blood pressure group compared to the normal, and were negatively correlated with both SBP and DBP even when the effects of related general and other dietary factors were excluded. Whereas energy, total, animal and vegetable protein, total and animal lipid, and riboflavin were higher in intake in the high blood pressure group than in fille normal, and they were in positive correlations with SBP and/or DBP. Vitamin A and ascorbic acid intakes were also negatively correlated with DBP, though ascorbic acid intake was not different between two groups. High blood pressure group preferred higher concentration of thin rice gruel than normal group and talc preferred salt concentrations was ill positive correlation with SBP. Serum and urinary levels of Ca, Mg, Ca/Mg ratio, Na, K and Na/K ratio did not show any differences between two groups. However serum Ca/Mg retio was in negative and se겨m Mg was ill positive correlations with SBP, and urinary Na excretion was negatively correlated with SBP. Calcium intake showed negative correlation with serum Ha and Na/K ratio. Our data indicated that dietary intake of Ca, energy, protein, lipid, vitamin A and C as well as salt preference were associated with blood pressure in adolescents. It might be assumed that Ca lowered blood pressure by increasing serum Ca/Mg ratio and decreasing serum Ca/K ratio though urinary excretion of Na.

• Journal of Korean Society for Atmospheric Environment
• /
• v.32 no.4
• /
• pp.360-371
• /
• 2016

The goal of this research is to examine the recent decade-long (2000~2014) trends of national background concentrations over China, Japan, and Korea. Based on the Long-range Transboundary Air Pollutants in Northeast Asia (LTP) project, which is three-party collaboration project among three countries, we investigated the long-term trends of national background $PM_{10}$ concentrations in three countries over the recent 15 years, including the 2008 Beijing Olympic Game period. In accordance with the agreement among three countries, a total of 8 national background sites: three national background monitoring sites in China (2 sites in Dalian, and 1 in Xiamen), three sites in Korea (Ganghwa, Gosan, and Taean), and two sites in Japan (Oki and Rishiri), were chosen for the trend analysis. The results showed that Chinese background concentration recorded the highest level overall. However, the rapid declining recent trends of annual median ($50^{th}$-percentile) values were surprisingly detected since 2006 or 2007 in every site in China, with the most rapidly decreasing rate (- $18.6{\pm}10.3%$/year) over 2006~2007, and the second most rapidly decreasing rate (- $18.0{\pm}1.5%$/year) over 2007~2008. Based on the previous statistical literature, we concluded that this declining trends were due to the emission reduction of $PM_{10}$ concentrations in China for 2008 Beijing Olympic Game. In Korea, Ganghwa was also showing the decreasing trends over the recent years since 2006, which is also well accorded with the decreasing period of Chinese background concentrations. Taean also implied some impact of Beijing Olympic Game, showing small but detectable decreasing trends, while Gosan showed the increasing tendencies probably due to the near-urban influences. However, since 2012, most sites in both China and Korea showed strong increasing trends, undoubtedly implying the increasement of both emission in China and its long-range transport process toward Korea. Two sites in Japan, Oki and Rishiri recorded the lowest level of $PM_{10}$ level during whole period with the smallest deviations of measurements. Other discussions including the decade-long trends of $5^{th}$, $10^{th}$, $25^{th}$, $50^{th}$, $75^{th}$, $90^{th}$, $95^{th}$-percentiles of $PM_{10}$ background concentrations in three countries were also comparatively addressed here.

• Journal of Korean Society of Environmental Engineers
• /
• v.38 no.10
• /
• pp.558-565
• /
• 2016

Water quality data including flow rates and BOD/COD/T-N/T-P/SS/TOC concentrations in Nakdong river tributaries were analyzed to determine priority management areas using 699 data sets from 195 locations in 2015. It was pointed out that the coefficients of variation, the ratio of the standard deviation to the mean, for the concentrations and loading rates of BOD, T-P, and TOC in each monitoring location were so large that average values of water quality monitoring data might be not appropriate to determine the priority management areas among all 195 monitoring stations in Nakdoing river. Therefore we suggested two evaluation methods using each water quality data independently. In the first method the excess numbers of the BOD, T-P, and TOC concentrations comparing to the water quality standards in the medium-sized management areas in Nakdong river was evaluated for each monitoring station. In the second method the percentile ranks of the loading rates of the BOD, T-P, and TOC were obtained for each monitoring data. The two groups of the priority management areas determined by each method were compared and the water quality characteristics in Nakdoing river were investigated.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.17 no.2
• /
• pp.182-189
• /
• 2015

Climate departure from the past variability was projected to start in 2042 for Seoul. In order to understand the implication of climate departure in Seoul for urban agriculture, we evaluated the daily temperature for the June-September period from 2041 to 2070, which were projected by the RCP8.5 climate scenario. These data were analyzed with respect to climate extremes and their effects on growth of hot pepper (Capsicum annuum), one of the major crops in urban farming. The mean daily maximum and minimum temperatures in 2041-2070 approached to the $90^{th}$ percentile in the past 30 years (1951-1980). However, the frequency of extreme events such as heat waves and tropical nights appeared to exceed the past variability. While the departure of mean temperature might begin in or after 2040, the climate departure in the sense of extreme weather events seems already in progress. When the climate scenario data were applied to the growth and development of hot pepper, the departures of both planting date and harvest date are expected to follow those of temperature. However, the maximum duration for hot pepper cultivation, which is the number of days between the first planting and the last harvest, seems to have already deviated from the past variability.

• The Journal of Pediatrics of Korean Medicine
• /
• v.27 no.4
• /
• pp.57-67
• /
• 2013

Objectives The purpose of this study is to investigate the safety and effect of Biman-tang (BMT) on two different administration periods in the treatment of childhood overweight and obesity. Methods In retrospective study, 39 overweight and obese ($85^{th}$ percentile ${\leq}$ Body Mass Index (BMI)) children were treated with BMT from January 2006 to April 2013 at Korean Medical Clinic in Suwon, Korea. The primary outcomes were the changes in BMI and Obesity Index (OI) from baseline to the treatment groups. Secondary outcomes included the changes in height, weight and safety of the medicine. Comparisons of BMI, OI, height and weight between the short-period (SP) treatment group and the long-period (LP) treatment group were done by using ANCOVA. Results The change of the mean of BMI ($-0.5{\pm}0.6kg/m^2$ vs $-1.4{\pm}0.8kg/m^2$, respectively; p=0.003) and OI ($-3.6{\pm}3.9%$ vs $-9.7{\pm}4.7%$, respectively; p<0.001) showed significant reduction both in SP (n=16) and LP treatment group (n=23). The mean height showed no significant difference in both groups. The mean weight of LP treatment group showed significant reduction compared to SP treatment group ($-0.2{\pm}1.3kg$ vs $-1.6{\pm}1.6kg$, respectively; p=0.006). Most of the children were compliant to the medication and no serious adverse events were found in two groups. Conclusions These findings emphasize that BMT is effective in the treatment of childhood obesity and it requires at least 45 days of treatment for the best result.

• Clinical and Experimental Pediatrics
• /
• v.48 no.9
• /
• pp.935-938
• /
• 2005

Purpose : The aim of the present study was to ascertain whether the increase of carotid intima-media thickeness(cIMT) as one of premature pathologic changes of atherosclerosis, was present in obese children compared to normal weight children. Methods : The obese group consisted of 21 obese/overweight(body mass index(BMI) above 85 percentile of age, sex standards) children and the control group of 11 normal weight children. None of the children had any chronic illnesses or previous medication history. We investigated the age, sex, height, weight, and systolic/diastolic blood pressure. We measured cIMT by ultrasonogram. In 19 of the obese group, we tested the serum glucose level, liver transaminase level, and cholesterol level etc. Results : The increase of cIMT in obese group did not achieved statistical significance(obese group vs. control group; 0.42 vs. 0.40 mm, P=0.0592). In addition, cIMT showed no significant correlation with any physical/laboratory variables including BMI(P=0.0585). Conclusion : To our knowledge, this is the first study to measure the cIMT in Korean children. Though the results approached statistical significance, we could not prove an increase of cIMT in obese children or an association between cIMT and BMI, due to the study's small sample size. In the future, larger and more extensive trials are needed.

• Clinical and Experimental Pediatrics
• /
• v.53 no.6
• /
• pp.705-710
• /
• 2010

Purpose: To determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit. Methods: A retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neonatal intensive care unit between 1990 and 2007. Results: The rate of prenatal diagnosis was 12%. The average gestational age and birth weight were $37^{+2}$ weeks and $2.5{\pm}0.7kg$, respectively. Thirty-one infants were born prematurely (32%). Type C was the most common. The mean gap between the proximal and distal esophagus was 2 cm. Esophago-esophagostomy was performed in 72 patients at a mean age of 4 days after birth; gastrostomy or duodenostomy were performed in 8 patients. Forty patients exhibited vertebral, anorectal, cardiac, tracheoesophageal, renal, limb (VACTERL) association with at least 2 combined anomalies, and cardiac anomaly was the most common. The most common post-operative complications were esophageal stricture followed by gastroesophageal reflux. Balloon dilatation was performed for 1.3 times in 26 patients at a mean age of 3 months. The mortality and morbidity rates were 24% and 67%, respectively, and the most common cause of death was sepsis. The weight of approximately 40% patients was below the 10th percentile at 2 years of age. Conclusion: Mortality and morbidity rates of patients with TEF and EA are high as compared to those of infants with other neonatal surgical diseases. Further efforts must be taken to reduce mortality and morbidity and improve growth retardation.

• Clinical and Experimental Pediatrics
• /
• v.55 no.11
• /
• pp.438-444
• /
• 2012

Mucolipidosis II (ML II) or inclusion cell disease (I-cell disease) is a rarely occurring autosomal recessive lysosomal enzyme-targeting disease. This disease is usually found to occur in individuals aged between 6 and 12 months, with a clinical phenotype resembling that of Hurler syndrome and radiological findings resembling those of dysostosis multiplex. However, we encountered a rare case of an infant with ML II who presented with prenatal skeletal dysplasia and typical clinical features of severe secondary hyperparathyroidism at birth. A female infant was born at $37^{+1}$ weeks of gestation with a birth weight of 1,690 g (<3rd percentile). Prenatal ultrasonographic findings revealed intrauterine growth retardation and skeletal dysplasia. At birth, the patient had characteristic features of ML II, and skeletal radiographs revealed dysostosis multiplex, similar to rickets. In addition, the patient had high levels of alkaline phosphatase and parathyroid hormone, consistent with severe secondary neonatal hyperparathyroidism. The activities of ${\beta}$-D-hexosaminidase and ${\alpha}$-N-acetylglucosaminidase were moderately decreased in the leukocytes but were 5- to 10-fold higher in the plasma. Examination of a placental biopsy specimen showed foamy vacuolar changes in trophoblasts and syncytiotrophoblasts. The diagnosis of ML II was confirmed via GNPTAB genetic testing, which revealed compound heterozygosity of c.3091C>T (p.Arg1031X) and c.3456_3459dupCAAC (p.Ile1154GlnfsX3), the latter being a novel mutation. The infant was treated with vitamin D supplements but expired because of asphyxia at the age of 2 months.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.5
• /
• pp.190-198
• /
• 2018

The purpose of this study was intended to provide baseline data to develop child health education for multicultural mothers. Participants were 30 multicultural mothers in B city multicultural family support centers and 20 persons in charge of child healthcare in B city. From Dec 2016 to Jan 2017 a self-report instrument was used to measure general characteristics, status, importance, implementation, and needs of child healthcare education. The data were analyzed through frequencies, Chi-squared test, and analysis of variance using the SPSS 20.0 program. Fifty-seven percent of transcultural mothers had not participated in child healthcare education before. There was no significant difference between importance and implementation of child healthcare education. In Borich analysis, "Safety accident prevention", "Toilet training", and "Growth and development" were in the 25th percentile. In Locus for Focus, "Safety accident prevention", "Bathing", "Baby massage", "Toilet training", and "Weaning food" were in the HH area. In comparison with importance of child healthcare education, multicultural mothers, and persons in charge of child healthcare, multicultural mothers had significantly higher scores than persons in charge of child healthcare. Therefore, in order to meet multicultural mothers' educational needs for child healthcare education, child healthcare information should be developed.