• Journal of Digestive Cancer Research
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• 제7권1호
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• pp.1-4
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• 2019

It is important to choose the appropriate treatment option for patients with colorectal cancer (CRC), because it could affect the prognosis of patients. Chemotherapy is effective in prolonging survival and time to progression in patients with advanced CRC. Adjuvant chemotherapy have been reported to reduce the recurrence rate of colorectal cancer by 30% in patients with stage 3 or high risk of stage 2 CRC. Although palliative chemotherapy does not offer long-term benefits, as life expectancy remains below 12 months in most of those receiving treatment, recent developments in the treatment including target agents and immunotherapy have improved the median overall survival time in patients with metastatic CRC by up to 30 months. Chemotherapy for patients with CRC is classified into neoadjuvant, adjuvant, and palliative therapy according to the status of patients. In this review, I summarized the chemotherapy for patients with CRC, which applying in clinical practice.

• 성인간호학회지
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• 제22권6호
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• pp.570-581
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• 2010

Purpose: This study was conducted to develop a Cancer Patient Guide with patients involvement using evidenced based practice research. The purpose of this patient guide was to help patients undergoing chemotherapy to manage their nausea and vomiting based on evidence. Methods: The design of the research was a methodological study. The participants consisted of seven cancer patients who were asked about their ' need for nausea and vomiting management, and secondly, 16 expert & 15 cancer patients to evaluate the Cancer Patient Guide using the DESCERN tool. Results: 1) Sixty-four relevant research evidences based articles were reviewed. 2) Patients were interviewed as to their needs in controlling nausea and vomiting. 3) The preliminary Cancer Patient Guide utilizing the research evidenced and the cancer patients interviews was then evaluated and revised by the experts and cancer patients. Lastly, the Cancer Patient which included an overview of chemotherapy, pathophysiology of nausea & vomiting, pharmacological and non-pharmacological interventions was finalized with each intervention supported by research evidence and patients' narratives of their experience. Conclusion: The Cancer Patient Guide was developed using evidenced based research and cancer patients in-put and be used to improve patients' self-management skill of nausea and vomiting in chemotherapy. The guide t also provides evidence based patient friendly information and contributes as a baseline data for developing and evaluating evidence-based guide for patients.

• 한국의류산업학회지
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• 제16권6호
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• pp.849-859
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• 2014

This study developed adaptive clothing to increase psychological comfort and protection for dementia patients. Our research method and data collection were as follows. The author selected and interviewed 10 caregivers and nurses to understand dementia patient behavior. The author collected eight pieces of clothing designed for dementia patients that are sold in Korean and overseas markets. We then analyzed garment details, open systems, close systems, and expected functions. Adaptive clothing for dementia patients were developed based upon our research. The results are as follows. First, dementia patients' behavior differed by dementia patient symptoms. Second, all items sold in Korean and overseas markets were jump suits designed to prevent behavior characteristic of dementia patients. Third, the author designed and manufactured five pieces of adaptive clothing for dementia patients that included two for mild dementia patients and three for moderate dementia patients. A panel of 50 caregivers gave high marks to developed clothing in regards to functionality, hygiene, patient human rights and aesthetics. The adaptive clothing of dementia patients from this research will increase the psychological and emotional satisfaction of dementia patients.

• 대한간호학회지
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• 제6권2호
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• pp.18-24
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• 1976

This study to find out the causes and degree of anxiety experienced by hospitalized patients, with the objective of instituting improvement of Nursing care program based on the needs of patients. The present study was carry out from July 1 , 1975 to October 10, 1975 with 168 patients random sampling from those admitted of Kyung Hee Medical Center. The Questionnaire form included 47 questions which are considered to be anxiety events for admitted patients and was divided into four areas namely, such events related to 1) hospital environment, 2) Psychology and emotion, 3) Nursing care and treatment, and 4 )Education. The results of the study were as follows : 1) Most of the respondents (70.09%) felt uneasy about their disease affected by the behaviors of medical personnel. 2) Regarding the correlation between anxiety felt by patients and their educational level. Only 9 sub- items of 47 items showed significant difference. 3) There was revealed no particular significance in the correlation between anxiety felt by patients and period of hospitalization. 4) Only 5 sub- items out of 47 items showed significant difference ill the correlation between anxiety felt by patients and previous experience of operation. 5) Only 3 sub-items out of 47 items showed signigicant difference in the correlation between anxiety felt day patients and previous experience of hospitalization. 6) Regarding the extent of anxiety felt by patients, "insufficient explanation about meals" showed the highest score followed. "The visit of physicians and Nurses to the patient is too frequent " showed the lowest score and "Nurses change too frequently the physical posture of patients" followed.

• 대한간호학회지
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• 제36권7호
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• pp.1145-1153
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• 2006

Purpose: The purpose of this study was to discover kidney transplant and hemodialysis patients' quality of life(QOL) and provide basic data to improve their QOL. Method: One hundred two hemodialysis patients and 106 kidney transplant patients were given a self-administered questionnaire from Mar. 6 to Mar 31, 2006. The instrument consisted of demographic variables, therapeutic-related characteristics and QOL. Collected data was processed using the SPSS 12.0 statistical program for real numbers, percentages, ANCOVA, t-test, ANOVA, Stepwise multiple regression and the Scheffe test. Results: Kidney transplantpatients' QOL was higher than hemodialysis patients. The demographic variables which showed a significant difference in overall QOL were religion, children and monthly income for kidney transplantpatients and educational background for hemodialysis patients. The therapeutic-related variable which showed a significant difference in overall QOL was the patients' perceived health condition for both groups. The influencing factor on overall QOL for both groups was the health condition perceived by themselves. The total variance of the variable for QOL was 42% for kidney transplant patients and 19% for hemodialysis patients. Conclusion: This study revealed that kidney transplant patients have a higher QOL and how patients perceive their health is the strongest influencing factor for QOL. However, there is a large difference between the demand and supply of kidney donors. To solve this problem the standards for donation should be reviewed and revised.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5729-5733
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• 2012

Background and Objectives: This study aimed to present the clinicopathological characteristics and treatment of patients with bladder carcinoma with sarcomatoid differentiation at our institution. Methods: Between 1995-2009, 950 patients were followed-up for bladder carcinoma. Among them, 14 patients with sarcomatoid carcinoma were retrospectively reviewed, and their clinical, pathological features and treatment were recorded. Results: Median age of the patients was 65 years (range: 41-86 years), 12 (86%) being male and 2 (14%) female. All the patients presented with hematuria and 11 (88%) had a history of smoking. The tumor growth pattern was solid in 10 patients, papillary in 2, and mixed in 2. In all, 5 of the patients had urothelial carcinoma with sarcomatoid differentiation and 9 were diagnosed with sarcomatoid carcinoma. Five patients underwent radical cystectomy with ileal conduit surgery, 2 patients refused cystectomy, and 8 patients underwent re-TUR. Following diagnosis, 12 of the patients died in mean 10.7 months (range: 1-48 months). Conclusion: Urothelial carcinomas with sarcomatoid features are aggressive and are usually at advanced stage at the time of diagnosis. The outcomes of multimodal treatment are not satisfactory. Significant findings of the present study are that early diagnosis positively affect survival and that gemcitabine and cisplatin in combination can positively affect survival.

• Journal of Trauma and Injury
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• 제29권4호
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• pp.151-154
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• 2016

Purpose: To evaluate the association between time to surgery and injury severity score (ISS). Methods: Medical charts and records were reviewed for polytrauma patients who underwent trauma surgery from November 2014 to March 2016. The patients were divided into two groups based on the ISS. Results: Among the 217 operated patients, 22 patients underwent first and second surgery. The patients with an ISS over 17 (mean 13.0 days) had a longer interval between surgeries than patients with an ISS of 17 or less (mean 7.5 days) (p=0.031). One hundred and twenty-one patients only underwent elective surgery and there is a positive correlation between ISS and time to elective surgery (p<0.028, Pearson's correlation coefficient=0.224). Seventy-four patients underwent emergent surgery only. Among these, the patients with an ISS of 17 or less underwent general surgery (86%) but the patients with an ISS more than 17 underwent neurological surgery (47%). Conclusion: Patients with high ISS need critical care during the preoperative and postoperative period.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2583-2585
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• 2016

Objectives: To evaluate efficacy and toxicity in patients with advanced lung cancer, including non-small cell and small cell variants (NSCLC and SCLC), treated with thalidomide plus chemotherapy. Methods: Fourteen patients with advanced lung cancer were scheduled to receive chemotherapy combined with thalidomide. All patients in this study received thalidomide (100 mg orally per night before sleeping, produced by Changzhou Pharmaceutical Factory Co.Ltd) after the start of chemotherapy for at least 14 days. Chemotherapy was administered according to the condition of patients. After at least 14 days of treatment, efficacy and toxicity were evaluated. Results: There were 6 female and 8 male patients with advanced lung cancer recruited into this study, including 2 with SCLC and 12 with NSCLC. The median age was 56.7 (44-65) years. Progressive disease was observed in 12 patients (12/14), and stable disease in 2 (2/14). Grade 1 to 2 myelosuppression was observed in 4/14 patients, and Grade 1 to 2 elevation of hepatic enzymes was recorded in 5/14 patients. Adverse effects on the gastrointestinal tract were documented in 2/14 patients, all beingGrade 1. No Grade 3-4 toxicity was recorded. No treatment related deaths occurred. Conclusions: Our results demonstrate that thalidomide combined with chemotherapy is mildly effective and safe for treating patients with advanced lung cancer. However, further evaluation of this combination is warranted.

• 대한간호학회지
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• 제44권4호
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• pp.437-445
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• 2014

Purpose: This study was done to identify pain perception (P-PER) by nurses and pain expression (P-EXP) by patients in critical care units (ICUs) and degree of agreement between nurses' P-PER and patients' P-EXP. Methods: Nurses' P-PER was measured with a self-administered questionnaire completed by 99 nurses working in ICUs during May, 2013. Patients' P-EXP was measured with the Critical Care Non-Verbal Pain Scale through observations of 31 ICU patients during nine nursing procedures (NPs) performed between May and July, 2013. Results: Nurses' P-PER was from 4.49 points for nasogastric tube (NGT) insertion to 0.83 for blood pressure (BP) measurement based on a 9-point scale, Patients' P-EXP was 4.48 points for NGT to 0.18 for BP measurement based on a 10-point scale. Eight NPs except oral care showed higher scores for nurses' P-PER than for patients' P-EXP. Position change (p=.019), subcutaneous injection (p<.001), blood sugar test (p<.001), and BP measurement (p<.001) showed significant differences between nurses' P-PER and patients' P-EXP. Conclusion: Nasogastric tube (NGT) insertion was scored highest by both nurses and patients. Eight NPs except 'oral care' showed nurses' P-PER was higher or similar to patients' P-EXP, which indicates that nurses may overestimate procedural pain experienced by patients.

• 대한추나의학회지
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• 제5권1호
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• pp.205-211
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• 2004

Objective : This study is designed to provide clinical data about patients of scoliosis for clinicians. Methods : We investigated 112 patients who have signs and symptoms of scoliosis. visited Vertebral -Joint Center of Conmaul Oriental Medical Hospital from January 2003 to July 2004. We measured Cobb's angle in the 112 patients' X-ray of full spine AP and lateral view and also analyzed age, sex, chief complaints. Results : 1. We investigated 72 female and 40 male patients. The most common distribution of age was 20's in both sex. 2. In the scoliosis angle : The average scoliosis angle was $9.27^{\circ}{\pm}6.06^{\circ}$ in 112 patients. The average scoliosis angle of 40 male patients was$8.9^{\circ}{\pm}6.77^{\circ}$. The average scoliosis angle of 72 female patients was $9.48^{\circ}{\pm}5.67^{\circ}$. 3. The most common region of scoliosis was thoracic spine with 37 patients. 4. The most common chief complaint was low back pain with 69 patients. In the 48 patients. self awareness of scoliosis was included in the chief complaint.