• Title/Summary/Keyword: patient variation

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Analysis of High Dose Rate Intracavitary Radiotherapy(HDR-ICR) Treatment Planning for Uterine Cervical Cancer (자궁경부암의 고선량율 강내치료 선량계획 분석)

  • Chai, Gyu-Young
    • Radiation Oncology Journal
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    • v.12 no.3
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    • pp.387-392
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    • 1994
  • Purpose : This study was done to confirm the reference point variation according to variation in applicator configuration in each fractioation of HDR ICR. Materials and Methods : We analyzed the treatment planning of HDRICR for 33 uterine cervical cancer patients treated in department of therapeutic radiology from January 1992 to February 1992. Analysis was done with respect to three view points-Interfractionation A point variation, interfractionation bladder and rectum dose ratio variation, interfractionation treatment volume variation. Interfractionation A point variation was defined as difference between maximum and minimum distance from fixed rectal point to A point in each patient. Interfractionation bladder and rectum dose ratio variation was defined as difference between maximum and minimum dose ratio of bladder or rectum to A point dose in each patient, Interfractionation treatment volume variation was defined as difference between miximum and minimum treatment volume which absorbed over the described dose-that is, 350 cGy or 400 cGy-in each patient. Results The mean of distance from rectum to A point was 4.44cm, and the mean of interfractionation distance variation was 1.14 cm in right side,1.09 cm in left side. The mean of bladder and rectum dose ratio was $63.8\%$ and $63.1\%$ and the mean of interfractionation variation was $14.9\%$ and $15.8\%$ respectively. With fixed planning administration of same planning to all fractionations as in first fractionation planning-mean of bladder and rectum dose ratio was $64.9\%$ and $72.3\%$.and the mean of interfraction variation was $28.1\%$ and $48.1\%$ reapectively. The mean of treatment volume was $84.15cm^3$ and the interfractionation variation was $21.47cm^2$. Conclusion : From these data, it was confirmed that there should be adapted planning for every fractionation ,and that confirmation device installed in ICR room would reduce the interfractionation variation due to more stable applicator configuration.

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Variation in radial head fracture treatment recommendations in terrible triad injuries is not influenced by viewing two-dimensional computed tomography

  • Eric M. Perloff;Tom J. Crijns;Casey M. O'Connor;David Ring;Patrick G. Marinello;Science of Variation Group
    • Clinics in Shoulder and Elbow
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    • v.26 no.2
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    • pp.156-161
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    • 2023
  • Background: We analyzed association between viewing two-dimensional computed tomography (2D CT) images in addition to radiographs with radial head treatment recommendations after accounting for patient and surgeon factors in a survey-based experiment. Methods: One hundred and fifty-four surgeons reviewed 15 patient scenarios with terrible triad fracture dislocations of the elbow. Surgeons were randomized to view either radiographs only or radiographs and 2D CT images. The scenarios randomized patient age, hand dominance, and occupation. For each scenario, surgeons were asked if they would recommend fixation or arthroplasty of the radial head. Multi-level logistic regression analysis identified variables associated with radial head treatment recommendations. Results: Reviewing 2D CT images in addition to radiographs had no statistical association with treatment recommendations. A higher likelihood of recommending prosthetic arthroplasty was associated with older patient age, patient occupation not requiring manual labor, surgeon practice location in the United States, practicing for five years or less, and the subspecialties "trauma" and "shoulder and elbow." Conclusions: The results of this study suggest that in terrible triad injuries, the imaging appearance of radial head fractures has no measurable influence on treatment recommendations. Personal surgeon factors and patient demographic characteristics may have a larger role in surgical decision making. Level of evidence: Level III, therapeutic case-control study.

A Study on Variation Types in Celiac Axis and Superior Mesenteric Artery using 3D Volume Rendering of MDCT (MDCT의 3차원 볼륨렌더링을 이용한 복강축과 위창자간막동맥의 변위 형태에 관한연구)

  • Lee, Jeong-Keun;Jang, Young-Ill;Jang, Seong-Joo
    • Journal of radiological science and technology
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    • v.36 no.2
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    • pp.131-139
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    • 2013
  • The aim of this study was to evaluate the variation which based on Celiac axis and SMA using by CT volume rendering images. 613 patients underwent abdominal CTA, there were 552 patients (99.05%, TypeI, II) with normal anatomical form and 61 (9.95%, Type III~XII) with variation. TypeI was 339(55.31%), Type II was 213 (34.74%), Type III was 18 (2.93%), Type IV was 12 patients (1.95%), Type V was 11 patient (1.79%), Type VI was 9 patients (1.46%), Type VII was 6 patients (0.97%), Type VIII was 1 patient (0.16%), Type IX was 1 patient (0.16%), Type X was 1 patient (0.16%), Type XI was 1 patient (0.16%), and Type XII was 1 patient (0.16%) into totally new types of variation. In conclusion, we could found 9 new types of variation by classifying based on celiac axis and superior mesenteric artery. These results were considered to be an important opportunity for a new vessel map.

Medical Service Variation of Urinary Incontinence Surgery and Uterine Polypectomy Using a Multilevel Analysis (다수준 분석을 이용한 요실금수술과 자궁폴립제거술의 의료서비스 변이)

  • Kim, Sang Me;Ahn, Bo Ryung;Kim, Jeong Lim;Lee, Hae Jong
    • Health Policy and Management
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    • v.30 no.1
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    • pp.82-91
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    • 2020
  • Background: This study investigates the influence factors of medical service variations using medical charge and the length of stay (LOS) for urinary incontinence surgery and uterine polypectomy. Methods: The National Health Insurance claims data and Medical Resource Report by the Health Insurance Review & Assessment Service in 2016 were used. Frequency analysis, one-way analysis of variance, and Bonferroni post-hoc tests were executed for each surgery. A multilevel analysis was executed to assess the factors to the medical charge and LOS for each surgery in patient, doctor, and hospital level. Results: Fifty-two point eight percent of urinary incontinence surgery and 87.1% of uterine polypectomy were distributed in general and tertiary hospitals. Among three levels, the patient level variation was 61.5% or 77.2% in medical charge and 93.9% or 96.3% in LOS, respectively. The doctor level variation was 29.6% or 22.6% in medical charge and 0.6% or 0.0% in LOS, respectively. The institution level variation was 8.9% or 0.2% in medical charge and 5.5% or 3.7% in LOS, respectively. Number of other disease and organizational type were main factors that affected the charge and LOS for urinary incontinence surgery and uterine polypectomy. Conclusion: Medical service variations of the urinary incontinence surgery and uterine polypectomy were the largest for the patient level, followed by doctor level for the medical charge, and the institution level for the LOS.

Statistical Diagnosis(SPD) for Control of SARS Epidemic Situation of Beijing

  • Zhang, Gongxu;Sun, Jing
    • International Journal of Quality Innovation
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    • v.4 no.1
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    • pp.46-53
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    • 2003
  • Under the strong leadership of Chinese Government to the anti-SARS struggle, the situation has been successfully controlled. Since May 1 of 2003, the Ministry of Health of China published daily the number of newly increased SARS patient of Beijing, the authors analyzed these data using $X_cs$$-R_scs$ cause-selecting control charts of Statistical Diagnosis(SPD) Theory. Data about number of newly increased SARS patient consists of two kinds of variation: random variation and tendency variation of SARS epidemic. It is concluded that SARS epidemic of Beijing was already controlled since May 9 of 2003.

Between-Hospital Variation in All-Cause Mortality for Potentially Avoidable Hospitalizations in Older People

  • Kim, Jae-Hyun;Lee, Yunhwan
    • Health Policy and Management
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    • v.29 no.2
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    • pp.220-227
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    • 2019
  • Background: Potentially avoidable hospitalizations (PAH) contribute to an increased post-discharge mortality. Methods: To investigate the between-hospital variation and the relationship between all predictors and mortality after discharge among older adults with PAH, we studied 15,186 older patients with PAH in 2,200 hospitals included in the National Health Insurance Service-Senior claims database from 2002 to 2013. Multivariable multilevel logistic regression analyses were performed to analyze the variance at between-hospital for mortality after accounting for differences in patient characteristics. Results: The between-hospital variation in mortality that could be attributed to hospital practice variations were 37.6% at 1-week to 13.9% at 12-month post-discharge, after adjustment for individual patient characteristics and hospital-level factors. Hospital-level factors significantly explained mortality at 3 weeks after discharge. Clinics, compared with general hospitals, demonstrated a 2.75 times higher likelihood of deaths at 3-week post-discharge (p<0.001). Compared with private hospitals, public hospitals exhibited 1.61 times higher odds of 3-week mortality (p=0.01). Conclusion: This study demonstrates considerable between-hospital variations in PAH-related mortality that could be attributed to hospital practices. Monitoring of hospitals to identify practice variations would be warranted to improve the survival of older patients with PAH.

A Study on Regional Medical Utilization Variation of Hospital Inpatients in Korea (우리나라 병원급 이상 의료기관 입원환자의 지역별 의료이용의 변이에 관한 연구)

  • Seo, Young-Suk;Lee, Kyung-Soo;Park, Jong-Ho;Kang, Sung-Hong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.4
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    • pp.1511-1519
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    • 2010
  • The purpose of this study was to analyze regional medical utilization variation of hospital inpatients and to suggest policy for the allocation of medical service in Korea. We analyzed the relationship among medical service, city size, income level and regional medical utilization variation of hospital inpatients. The patient survey report of 2005 year in Ministry of Health and Welfare was used for this study. To adjust on the factor age and sex, we used direct standardization method. Findings of the research were summarized as follows ; First, standardization discharge rate on patient was different in the district. city type, and number of beds. Second, standardization length of stay of patient was different in region, city type, and number of beds.

Variations in hospital length of stay for diagnosis-related groups among health care institutions (DRG 지불제도 참여기관의 재원일수 변이에 관한 연구)

  • Lee Kee-Sung;Kang Hee-Chung;Nam Chung-Mo;Cho Woo-Hyun;Kang Hye-Young
    • Health Policy and Management
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    • v.16 no.2
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    • pp.77-95
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    • 2006
  • The present study was conducted to examine the degree of variation in length-of-stay (LOS) among health care institutions participating in 17 diagnosis-related groups (DRGs) payment system and to find out hospital characteristics affecting the variation. Electronic medical claims data for treatments of severity classification '0' of 17 DRGs provided for two $years(2003{\sim}2004)$ were collected. For each DRG, the degree of variation in average LOS among health care institutions were analyzed using the random effect model. For DRGs showing significant differences in LOS, multiple regression analyses were performed to find out factors associated with LOS. Significant variations in LOS were observed 9 DRGs including unilateral/bilateral lens procedures, adult/child tonsilectomy, other anal procedures, bilateral adult/child herniorraphy, unilateral child herniorraphy, and hysterectomy, and hysterectomy using laparoscopic procedure. Among the 9 DRGs, five DRGs were selected to investigate the factors explaining for the variation. It was observed that the location of institution was significant predictors for all five DRGs. Within the same DRGs, LOS was significantly shorter among the institutions located in Seoul than those in other areas. As compared to clinics, hospitals and general hospitals/tertiary care institutions showed significantly longer LOS for DRGs of lens procedures, tonsilectomy, and other anal procedures. It is recommended that the institutions located in other than Seoul area benchmark the strategies of the institution in Seoul in efficiently managing LOS. Also, significant variation within the same severity classification such as other anal procedures implies the imminent need for improvement of patient classification system.

Statistical Method for Implementing the Experimenter Effect in the Analysis of Gene Expression Data

  • Kim, In-Young;Rha, Sun-Young;Kim, Byung-Soo
    • Communications for Statistical Applications and Methods
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    • v.13 no.3
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    • pp.701-718
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    • 2006
  • In cancer microarray experiments, the experimenter or patient which is nested in each experimenter often shows quite heterogeneous error variability, which should be estimated for identifying a source of variation. Our study describes a Bayesian method which utilizes clinical information for identifying a set of DE genes for the class of subtypes as well as assesses and examines the experimenter effect and patient effect which is nested in each experimenter as a source of variation. We propose a Bayesian multilevel mixed effect model based on analysis of covariance (ANACOVA). The Bayesian multilevel mixed effect model is a combination of the multilevel mixed effect model and the Bayesian hierarchical model, which provides a flexible way of defining a suitable correlation structure among genes.

Immunological ObservatioIn on Gandidiasis (Candida증(症) 발생(發生)의 면역학적(免疫學的) 기전(機轉)에 관(關)한 연구(硏究))

  • Kim, Hong-Sik
    • The Korean Journal of Mycology
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    • v.6 no.2
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    • pp.15-18
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    • 1978
  • The study was performed to investigate the inhibitory action on the growth rate of Candida albicans under the various immunological conditions, Candida albicans was grown in broth media containing 0.1ml. (in total broth volume 4.0ml.) of normal human serum, diabetic patient serum, albumin solution, artifical bulla content and nutrient solution as control subject. The inhibitory action of Candida albicans was indicated by mesurement of transparency rate with use of the spectrophotometer. The results are as follows: 1. Normal human serum shows inhibitory effect on the growth of the candida distinctly. 2. Albumin solution reveals almost similar to that of the effect of normal human serum. 3. Artificial bulla content which obtained by irradiation of ultraviolot ray after application of 1% 8-Methoxy-psolaren cream and the diabetic patient serum shows reduction of inhibitory effect as compared with that of the normal human serum. 4. It is estimated that the titer of negative effect of diabetic patient serum is not related with the variation of immunoglobulin titer in patient serum.

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