• Structural Engineering and Mechanics
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• 제5권4호
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• pp.471-490
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• 1997

In this paper, the classical Irons' patch tests which have been generally accepted for the convergence proof of a finite element are performed for Mindlin plate bending elements with a special emphasis on the nonconforming elements. The elements considered are 4-node and 8-node quadrilateral isoparametric elements which have been dominantly used for the analyses of plate bending problems. It was recognized from the patch tests that some nonconforming Mindlin plate elements pass all the cases of patch tests even though nonconforming elements do not preserve conformity. Then, the clues for the Mindlin plate element to pass the Irons' patch tests are investigated. Also, the convergent characteristics of some nonconforming Mindlin plate elements that do not pass the Irons' patch tests are examined by weak patch tests. The convergence tests are performed on the benchmark numerical problems for both nonconforming elements which pass the patch tests and which do not. Some conclusions on the relationship between the patch test and convergence of nonconforming Mindlin plate elements are drawn.

• Biomolecules & Therapeutics
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• 제2권1호
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• pp.71-76
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• 1994

Anti-inflammatory and analgesic activities and skin irritation of piroxicam patch were investigated. Piroxicam patch increased the pain threshold in rat hind paw inflamed by carrageenan and inhibited writhing induced by acetic acid in mice. Piroxicam patch also inhibited the carrageenan-induced edema in rat hind paw as well as the increased vascular permeability induced by histamine in rats. In adjuvant arthritis of rats, piroxicam patch showed anti-inflammatory effects. Skin irritation of piroxicam patch was tested in Newzealand White rabbits and evaluated by Primary Irritation Index of Draize. The results from skin irritation test showed that piroxicam patch seemed practically non-irritating. The result from the present study indicates that piroxicam may be useful without serious side effects as anti-inflammatory analgesics in this patch form.

• 기본간호학회지
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• 제23권1호
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• pp.12-20
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• 2016

Purpose: This study was done to examine the effects of lidocaine patch application to decrease pain and fear during blood sugar testing in elderly patients with DM. Methods: The participants were 56 elderly patients admitted to J geriatric hospital in G city, Korea. Of the elderly patient, 27 were assigned to the experimental group and 29 to the control group. Participants in the experimental group applied a lidocaine patch on the fingertip for 30 minutes before a blood sugar test. The control group applied a plaster on the fingertip. Pain was evaluated using a visual analogue scale and fear using the Procedure Behaviour Check List. The results were compared using paired t-test and t-test. Results: The scores for pain and fear were significantly lower in the experimental group compared to the control group. Conclusion: The lidocaine patch was found to be an effective local anesthetic to relieve pain and fear during blood sugar test in elderly patients with DM without any severe adverse events.

• Biomolecules & Therapeutics
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• 제4권2호
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• pp.202-204
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• 1996

Clonidine, an antihypertensive drug, stimulates postsynaptic $\alpha_2$adrenergic receptors in the CNS and lowers arterial pressure by erects on both cardiac output and peripheral resistance. However, many patients experience that sedation and xerostomia occured upon oral administration of clonidine. These side effects are due to high plasma peak concentration and can be avoided when clonidine is given transdermally. In this study, we performed the skin irritation test for transdermal administration of clonidine patch on New Zealand white rabbits. Twelve New Zealand white rabbits were divided into two groups according to the dose levels, respectively. After transdermal administration of clonidine patch with two doses, clinical manifestations, body weight loss and postmortem findings were observed. We could not find any significant evidence of skin irritation by transdermal administration of clonidine patch.

• 한국의류산업학회지
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• 제7권1호
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• pp.81-84
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• 2005

Skin patch test and antibacterial properties of the reaction products between poly(hexamethyl biguanide) hydrochloride and trimethylol melamine on textile fabrics were examined. Antibacterial activities of anti-microbial agent treated samples are very good. The reduction ratios against four kinds of colonies are 99.9 % after repeated laundering ten times. Skin patch test results for anti-microbial agent treated samples are almost-negative by Hi-scope judgement and macroscopical judgement.

• 국제강구조저널
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• 제18권4호
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• pp.1410-1419
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• 2018

Recently, a repair method by bonding patch plates is being applied to corroded steel structures. However, one of the issues of patch plate bonding repair is the brittle debonding of the patch plates. Generally, when the delamination of the patch plates occurs, the composite effect acting between the steel members and patch plates abruptly decreases. Therefore, to prevent the brittle debonding of the patch plates, a repair method combining an adhesive and stud bolts is proposed. Till date, tensile and compressive tests have been performed for the proposed method. In this study, plate bending tests were conducted to verify the effectiveness of this method under bending conditions. Furthermore, two types of epoxy resin-based adhesives were prepared to evaluate the effectiveness of the proposed method with different adhesive properties. The test results show that the proposed method is able to prevent the brittle debonding of the patch plates in the case of both epoxy resins.

• 정보보호학회논문지
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• 제30권6호
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• pp.1141-1149
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• 2020

산업제어망은 대부분 독립된 폐쇄망으로 설치 이후 장기적으로 운영되면서 OS가 업데이트 되지 않아 보안 위협이 증가하고 보안 취약성이 존재한다. 제로 데이 공격 방어에는 최신 패치 적용이 필수로 이루어져야 하지만 대규모 산업망에서는 물리적인 장치를 직접 다루는 특성으로 더 높은 실시간성과 무중단 운영이 요구되기 때문에 실 운영 중인 시스템에 적용하기 어렵다. 이 문제를 해결하기 위해 신뢰로운 패치 적용을 위한 유틸리티사 고유의 패치 영향성 평가가 필요하다. 본 논문은 패치 시험에 대한 개념설계로부터 시스템 구현과 실증적용을 아우르고 있다. 패치 영향성 평가 방법론으로서 패치를 적용하기 전과 후의 시스템 고유 기능, 성능, 행위를 기반으로 시험 유형을 분류하고 반복 실험을 통해 패치의 안전성을 판정하는 최대 허용치를 제안하였다. 이후 산업제어망에 직접 적용한 결과 99.99% 가용성을 보장하면서 OS패치가 업데이트 되었다.

• 대한치과의사협회지
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• 제52권2호
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• pp.96-104
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• 2014

The aim of this study was to investigate the frequency of positive patch test reaction to dental materials in patients with oral mucosal diseases. Epicutaneous patch test was performed in 110 patients with oral mucosal diseases; 41 patients with oral lichen planus(OLP), 44 patients with burning mouth syndrome(BMS), 25 patients with other oral mucosal diseases including recurrent aphthous ulcer and mucous membrane pemphigoid. The obtained results were as follows: Oral gold restorations were most common in patents with oral mucosal diseases and porcelain fused metal crown, implant appeared in the order. 33 of 110 patients did not appear skin reactions (negative, 30%) and 77 patients (positive, 70%) had skin reactions including redness, rash, blisters. Dental materials causing positive reaction to patch test were mainly as gold-sodium-thiosulfate (26.7%), nickel sulfate(Ni) (22.7%), cobalt chloride(Co) (14.7%), palladium chloride(Pd) (11.9%), potassium dichromate (10.7%) in order, respectively. In conclusion, old metal restorations could be the cause of oral mucosal diseases and epicutaneous patch test could be used as a tool to improve the oral conditions.

• 한국산학기술학회논문지
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• 제17권1호
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• pp.421-424
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• 2016

본 연구에서 남해안산 전복으로 부터 얻어진 일반 열수 전복 추출물과 발효추출물의 화장품 원료로서의 사용가능성을 평가하고자 기본적인 피부 안전성 시험으로 추물물과 이를 이용한 액정크림 제형에서의 피부 일차 첩포 테스트를 수행하였다. 비교군으로 정제수, 1,3-부틸렌글리콜, 액정크림으로 하였고 시료군은 전복추출물과 전복추출물을 함유한 액정크림 제형이었다. 피부 일차 첩포 테스트 결과, 비교군과 시료군 모두 피부의 자극이 없는 것으로 나타났다. 그러므로 전복 추출물이 화장품 원료로서 피부 안전성을 확인하였다.

• Structural Engineering and Mechanics
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• 제7권2호
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• pp.203-216
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• 1999

A previously proposed finite element formulation method is refined and modified to generate a new type of elements. The method is based on selecting a set of general solution modes for element formulation. The constant strain modes and higher order modes are selected and the formulation method is designed to ensure that the element will pass the basic single element test, which in turn ensures the passage of the basic patch test. If the element is to pass the higher order patch test also, the element stiffness matrix is in general asymmetric. The element stiffness matrix depends only on a nodal displacement matrix and a nodal force matrix. A symmetric stiffness matrix can be obtained by either modifying the nodal displacement matrix or the nodal force matrix. It is shown that both modifications lead to the same new element, which is demonstrated through numerical examples to be more robust than an assumed stress hybrid element in plane stress application. The method of formulation can also be used to arrive at the conforming displacement and hybrid stress formulations. The convergence of the latter two is explained from the point of view of the proposed method.