• The Journal of Korean Academy of Prosthodontics
• /
• v.42 no.2
• /
• pp.125-132
• /
• 2004

Statements of problem: All ceramic fixed partial denture cores can be made by the slip casting method and the advanced alumina tape method. The fracture resistance of these core connector areas is relatively low. Purpose: The purpose of this study is to standardize the appropriate volumetric figure and location of the connectors in the alumina core fabricated in alumina tape to be used in fixed partial dentures by way of topology optimization. Material and method: A maxillary anterior three-unit bridge alumina core with teeth form and surrounding periodontal apparatus model was used to ultimately design the most structurally rigid form of the connector. Loadings from a $0^{\circ}$, $45^{\circ}$ and $60^{\circ}$ to the axis of each tooth were applied and analyzed with the 3-D finite element analysis method. Using the results from these experiments, the topology optimization was applied and the optimal reinforcement layout of connector was obtained and the detail shape in the fixed partial denture core was designed. Results: The modified prosthesis with the form of a bulk in the lower lingual surface of the connector in the event, reduced the stress concentration up to 20% in the 3-D FEA. Conclusion: The formation of a bulk in the lower lingual connector area of an alumina core for a fixed partial denture decreases the stress to a clinically favorable measure but does not harm the esthetic point of view. This result illustrates the possibility of clinical application of the modified form designed by the topology optimization method.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.9 no.3 s.43
• /
• pp.77-85
• /
• 2005

After the collapse of the World Trade Center in september 11, 2001 and due to the frequent fire-caused damages of buildings during earthquake attacks, social concerns have been increased for the fire proof of the structural members of buildings. Recently, researches have been conducted to improve the fire resistance for building members not by the traditional ways but by utilizing the fire-resisting characteristics of reinforced concrete and structural characteristics of H-steel. In this paper, laboratory tests were conducted in room temperature to investigate the structural performance of the composite beams, which were developed to improve the fire resistance, comprising with concrete incasement between upper and lower flanges of H steel. From the experimental results, the displacement ductility factors of $6\~8$ were obtained. The difference of flexural behavior ol H steel-partial concrete incased composite beams with various composite details seems to be minor. The amount of longitudinal rebars is the most influential factor for the flexural strength of the composite beams. Therefore, if this type of composite beams are selected for designing a building located in moderate seismic lone, identical beam size could be used in several stories of the building.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.15 no.5
• /
• pp.207-212
• /
• 2015

Continuous, high-quality supply of electrical energy is the backbone of any modern economy. Any equipment operating at a power station must be reliable and safe. All major power supply components such as transformers, cables, generators, and switchgear need to be kept in perfect operating condition. The lifetime of power cables, used as the main means of transferring electric power, is understood to be about 30 years, from the time of manufacturing. The dielectrics between two conductors of a cable must be able to withstand electrical stresses from high-voltage input. This condition should be verified throughout the lifetime of the cable system. Several techniques, such as VLF-tan${\delta}$, partial discharge, and insulation resistance are used in order to determine the operating conditions of cables. In this paper, we present our work on insulation resistance to diagnose cables in operation at the Western Power station in Taean, Chungcheong Namdo Province, South Korea. As a result we have found cables the life time of which is 38 years.

• Journal of Technologic Dentistry
• /
• v.34 no.3
• /
• pp.237-245
• /
• 2012

Purpose: This study was conducted to evaluate the corrosion resistance of metal ions of alloys and use the results as the dental health data. These were performed by examining the corrosion levels of Co-Cr alloys for the full and removable partial denture metal frameworks and porcelain-fused-to-metal crown, among the dental casting nonprecious alloys. Methods: The alloy specimens (N = 10) were manufactured in $15mm{\times}10mm{\times}1.2mm$ and stored in two types of corrosive solutions at $37^{\circ}C$ for seven days. The metal ions were quantitatively analyzed using the Inductively Coupled Plasma-Atomic Emission Spectrometer. Results: Of the three Co-Cr alloys, the Co ion concentration of the porcelain-fused-to-metal alloy was 1.512 ${\mu}g/cm^2$, which indicated the highest metal ion dissolution. The metal corrosion was higher in the more acidic pH 2.2 solution compared with the pH 4.4 solution. In all three Co-Cr alloys, Co ion dissolution was predominant in the two corrosive solutions. Conclusion: The corrosion resistance of the three Co-Cr alloys was high, indicating a good biocompatibility.

• Structural Engineering and Mechanics
• /
• v.90 no.5
• /
• pp.467-480
• /
• 2024

The mechanical properties and durability of concrete pavements may be degraded in extreme situations, resulting in the need for partial repair or total replacement. During the past few decades, there has been a growing body of research on substituting a portion of Portland cement with alternative cementitious materials for improving concrete properties. In this study, two different configurations of powdered and granulated blast furnace slag were implemented, replacing fine aggregates (by 12 wt.%) and Portland cement (by 0, 20, 40, and 60 wt.%) in the making of roller-compacted concrete (RCC) mixes. The specimens were fabricated to investigate the mechanical properties and durability specifications, involving freeze-thaw, salt-scaling, and water absorption resistance. The experimental results indicated that the optimum mechanical properties of RCC mixes could be achieved when 20-40 wt.% of powdered slag was added to concrete mixes containing slag aggregates. Accordingly, the increases in compressive, tensile, and flexural strengths were 45, 50, and 28%, in comparison to the control specimen at the age of 90 days. Also, incorporating 60 wt.% of powdered slag gave rise to the optimum mix plan in terms of freeze-thaw resistance such that a negligible strength degradation was experienced after 300 cycles. In addition, the optimal moisture content of the proposed RCC mixtures was measured to be in the range of 5 to 6.56%. Furthermore, the partial addition of granulated slag was found to be more advantageous than using entirely natural sand in the improvement of the mechanical and durability characteristics of all mixture plans.

• Journal of Technologic Dentistry
• /
• v.31 no.1
• /
• pp.63-74
• /
• 2009

Partial or complete prosthesis is needed when teeth are lost due to various kinds of reason. Artificial teeth recover occlusion instead of natural teeth. Artificial teeth are required of esthetics, fragile resistance and abrasive resistance. Artificial tooth is made of acrylic resin or porcelain. Nowadays, acrylic resin artificial teeth are mainly used. Acrylic resin teeth are occluded with natural teeth, gold alloy, Ni-Cr alloy or porcelain etc. Acrylic resin teeth have similar translucency, gloss of natural teeth. And it has good chemical bond with denture base material, but it has low wear resistance. The aim of this study is to compare wear resistance among several denture teeth(Endura, SR-orthosit-PE, Planustar) and between artificial resin denture teeth and opposing 3 restorative materials(gold, Ni-Cr alloy, porcelain). Wear tests were conducted with a rotating wear testing apparatus(pin-on-disk type wear tester) under conditions of rpm 180, 75 minutes and constant loading of 50N. The upper part was the cusp of maxillary first molar and the lower part was a disk type restorative materials. To make similar oral environment, water was supplied continually. The acrylic resin teeth wear was determined by weighing the cusp each 5 minutes during 75 minutes test. Vicker's hardness tester was used to evaluate the surface hardness of test specimens. The SEM was used to evaluate the wear surfaces. The results were as follows: 1. Wear rates of acrylic resin teeth opposing to the restorative materials were high in order of Porcelain, Gold, Ni-Cr alloy (p<.05). 2. Wear resistance rate opposing to the Porcelain disk, was shown in order of Endura, SR-orthosit-PE, Planustar. The wear rate of opposing to porcelain disk was above two times more than that of other groups (p<.05). 3. Wear resistance rates opposing to the Gold, Ni-Cr alloy disk, was shown in order of Endura, SR-orthosit-PE, Planustar (p<.05). 4. A degree of the surface hardness is directly proportional to the degree of wear resistance. There are statistically significant differences between each groups (p<.05).

• Mycobiology
• /
• v.46 no.2
• /
• pp.147-153
• /
• 2018

Certain beneficial microorganisms isolated from rhizosphere soil promote plant growth and induce resistance to a wide variety of plant pathogens. We obtained 49 fungal isolates from the rhizosphere soil of paprika plants, and selected 18 of these isolates that did not inhibit tomato seed germination for further investigation. Based on a seed germination assay, we selected four isolates for further plant tests. Treatment of seeds with isolate JF27 promoted plant growth in pot tests, and suppressed bacterial speck disease caused by Pseudomonas syringae pathovar (pv.) tomato DC3000. Furthermore, expression of the pathogenesis-related 1 (PR1) gene was higher in the leaves of tomato plants grown from seeds treated with JF27; expression remained at a consistently higher level than in the control plants for 12 h after pathogen infection. The phylogenetic analysis of a partial internal transcribed spacer sequence and the b-tubulin gene identified isolate JF27 as Aspergillus terreus. Taken together, these results suggest that A. terreus JF27 has potential as a growth promoter and could be used to control bacterial speck disease by inducing resistance in tomato plants.

• Geomechanics and Engineering
• /
• v.8 no.6
• /
• pp.811-828
• /
• 2015

Proper modelling of the basal resistance terms is key in simulating the motion of fluidized granular flow. In this paper, standard depth-averaged governing equations of granular flow are used together with the classical Coulomb, Voellmy, and velocity dependent friction models (VDFM). A high-resolution modified TVDLF method is implemented to solve the partial differential equations without numerical oscillations. The effects of basal resistance terms on the motion of granular flows such as geometric shape evolution, travel times and final deposits are analyzed. Based on the numerical results, the predictions of the front and rear end positions and developing length of granular flow with Coulomb friction model show excellent agreements with experiment results reported by Hutter et al. (1995), and illustrate the validity of the numerical approach. For the Voellmy model, the higher value of turbulent coefficient than reality may obtain more reasonable predicted runout for the small-scale avalanche or granular flow. The energy exchange laws indicate that VDFM is different from the Coulomb and Voellmy models, although the flow characteristics of both three models fit the measurements and observations very well.

• Journal of Welding and Joining
• /
• v.33 no.6
• /
• pp.21-26
• /
• 2015

Recently, application of UHSS(Ultra High Strength Steels) whose tensile strength is over 1000MPa to car body structure are growing due to great needs for light weighting and improved crash worthiness. However, their poor weldability is one of obstacles to expand selecting to car body. In this study, effect of Phosphorus contents on resistance spot weldability of high elongation DP980 steel whose Si content is over 1% was investigated. The cross tension strength (CTS) was decreased showing partial interface fracture as Phosphorus content increase because of solidification segregation of Phosphorus. In order to improve resistance spot weldability by modification of welding condition, in-situ post-weld heating pulse was introduced after main pulse. The optimum cooling time between main and post pulse and post-pulse current condtion were determined through FEM welding simulation and DOE tests. The CTS was increased about 1.5 time showing plug fracture. The decrease of Phosphorus segregation was found to be a major reason for weld ductility and CTS improvement.

• Molecules and Cells
• /
• v.44 no.5
• /
• pp.363-373
• /
• 2021

Immune checkpoint inhibitors have changed the paradigm of treatment options for non-small cell lung cancer (NSCLC). Monoclonal antibodies targeting programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) have gained wide attention for their application, which has been shown to result in prolonged survival. Nevertheless, only a limited subset of patients show partial or complete response to PD-1 therapy, and patients who show a response eventually develop resistance to immunotherapy. This article aims to provide an overview of the mechanisms of acquired resistance to anti-PD-1/PD-L1 therapy from the perspective of tumor cells and the surrounding microenvironment. In addition, we address the potential therapeutic targets and ongoing clinical trials, focusing mainly on NSCLC.