• Title/Summary/Keyword: parallel system

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Analysis of common and characteristic actions of Panax ginseng and Panax notoginseng in wound healing based on network pharmacology and meta-analysis

  • Zhen Wang ;Xueheng Xie ;Mengchen Wang ;Meng Ding ;Shengliang Gu ;Xiaoyan Xing;Xiaobo Sun
    • Journal of Ginseng Research
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    • v.47 no.4
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    • pp.493-505
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    • 2023
  • In recent years, an increasing number of reports have explored the wound healing mechanism of these two traditional Chinese herbal medicines- Panax ginseng and Panax notoginseng, but there is no systematic research on the related core functions and different mechanisms in the treatment of wound healing up to now. Based on network pharmacology and meta-analysis, the present work aimed to comprehensively review the commonality and diversity of P. ginseng and P. notoginseng in wound healing. In this study, a wound healing-related "ingredients-targets" network of two herbs was constructed. Thereafter, meta-analysis of the multiple target lists by Metascape showed that these two medicines significantly regulated blood vessel development, responses to cytokines and growth factors and oxygen levels, cell death, cell proliferation and differentiation, and cell adhesion. To better understand the discrepancy between these two herbs, it was found that common signaling pathways including Rap1, PI3K/AKT, MAPK, HIF-1 and Focal adhesion regulated the functions listed above. In parallel, the different pathways including renin-angiotensin system, RNA transport and circadian rhythm, autophagy, and the different metabolic pathways may also explained the discrepancies in the regulation of the above-mentioned functions, consistent with the Traditional Chinese Medicine theory about the effects of P. ginseng and P. notoginseng.

Distributed AI Learning-based Proof-of-Work Consensus Algorithm (분산 인공지능 학습 기반 작업증명 합의알고리즘)

  • Won-Boo Chae;Jong-Sou Park
    • The Journal of Bigdata
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    • v.7 no.1
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    • pp.1-14
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    • 2022
  • The proof-of-work consensus algorithm used by most blockchains is causing a massive waste of computing resources in the form of mining. A useful proof-of-work consensus algorithm has been studied to reduce the waste of computing resources in proof-of-work, but there are still resource waste and mining centralization problems when creating blocks. In this paper, the problem of resource waste in block generation was solved by replacing the relatively inefficient computation process for block generation with distributed artificial intelligence model learning. In addition, by providing fair rewards to nodes participating in the learning process, nodes with weak computing power were motivated to participate, and performance similar to the existing centralized AI learning method was maintained. To show the validity of the proposed methodology, we implemented a blockchain network capable of distributed AI learning and experimented with reward distribution through resource verification, and compared the results of the existing centralized learning method and the blockchain distributed AI learning method. In addition, as a future study, the thesis was concluded by suggesting problems and development directions that may occur when expanding the blockchain main network and artificial intelligence model.

Skeletal and dentoalveolar effects of different types of microimplant-assisted rapid palatal expansion

  • Hyeong-Yoon Choi;Sang-Min Lee;Jin-Woo Lee;Dong-Hwa Chung;Mo-Hyeon Lee
    • The korean journal of orthodontics
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    • v.53 no.4
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    • pp.241-253
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    • 2023
  • Objective: To evaluate the following null hypothesis: the skeletal and dentoalveolar expansion patterns in the coronal and axial planes are not different with two different types of microimplant-assisted rapid palatal expansion (MARPE) systems. Methods: Pretreatment (T0) and post-MARPE (T1) cone-beam computed tomography (CBCT) images of 32 patients (14 males and 18 females; mean age, 19.37) were analyzed. We compared two different MARPE systems. One MARPE system included the maxillary first premolars, maxillary first molars, and four microimplants as anchors (U46 type, n = 16), while the other included only the maxillary first molars and microimplants as anchors (U6 type, n = 16). Results: In the molar region of the U6 and U46 groups, the transverse expansion at the midnasal, basal, alveolar, and dental levels was 2.64, 3.52, 4.46, and 6.32 mm and 2.17, 2.56, 2.73, and 5.71 mm, respectively. A significant difference was observed in the posterior alveolar-level expansion (p = 0.036) and posterior basal-bone-level expansion (p = 0.043) between the groups, with greater posterior skeletal and alveolar expansion in the U6 group. Conclusions: Compared with the U46 group, the U6 group showed greater posterior expansion at the alveolar and basal-bone levels, with an almost parallel split. Both groups showed a pyramidal expansion pattern in the coronal view.

Design of a High-Speed Data Packet Allocation Circuit for Network-on-Chip (NoC 용 고속 데이터 패킷 할당 회로 설계)

  • Kim, Jeonghyun;Lee, Jaesung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.10a
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    • pp.459-461
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    • 2022
  • One of the big differences between Network-on-Chip (NoC) and the existing parallel processing system based on an off-chip network is that data packet routing is performed using a centralized control scheme. In such an environment, the best-effort packet routing problem becomes a real-time assignment problem in which data packet arriving time and processing time is the cost. In this paper, the Hungarian algorithm, a representative computational complexity reduction algorithm for the linear algebraic equation of the allocation problem, is implemented in the form of a hardware accelerator. As a result of logic synthesis using the TSMC 0.18um standard cell library, the area of the circuit designed through case analysis for the cost distribution is reduced by about 16% and the propagation delay of it is reduced by about 52%, compared to the circuit implementing the original operation sequence of the Hungarian algorithm.

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Effects of Robot-Assisted, Gait-Training-Combined Virtual Reality Training on the Balance and Gait Ability of Chronic Stroke Patients (가상현실훈련과 로봇보행훈련이 만성 뇌졸중 환자의 균형과 보행능력에 미치는 영향)

  • Dong-Hoon Kim;Kyung-Hun Kim
    • Journal of the Korean Society of Physical Medicine
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    • v.19 no.2
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    • pp.55-64
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    • 2024
  • PURPOSE: This study evaluated the effects of robot-assisted gait training combined with virtual reality training on balance and gait ability in stroke patients. METHODS: Thirty-one stroke patients were allocated randomly into one of two groups: robot-assisted gait training combined virtual reality training group (RGVR group; n = 16) and control group (n = 15). The RGVR group received 30 minutes of robot-assisted gait training combined with virtual reality training. Robot-assisted gait training was conducted in parallel using a virtual reality device. In the Control group, neurodevelopmental therapy was performed according to the function of chronic stroke patients. Both groups underwent training for 30 minutes, three times per week for eight weeks. The balance assessment system (BioRescue, Marseille, France), BBS, and TUG were used to evaluate the balance ability. The OptoGait (Microgate Srl, Bolzano, Italy) and 10 mWT were measured to evaluate the gait ability. The measurements were performed before and after the eight-week intervention period. RESULTS: Both groups showed significant improvement in their balance and gait ability during the intervention. RGVR showed significant differences in balance and gait ability compared to the control group groups (p < .05). These results showed that RGVR was more effective on balance and gait ability in patients with chronic stroke. CONCLUSION: RGVR can improve balance and gait ability, highlighting the benefits of RGVR. This study provides intervention data for recovering the balance and gait ability of chronic stroke patients.

A Psychological Interpretation of a Korean Fairy Tale "I live on my Fortune" - From the Perspective of Analytical Psychology - (민담 <내 복에 산다>의 분석심리학적 해석)

  • Young Sun Pahk
    • Sim-seong Yeon-gu
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    • v.25 no.2
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    • pp.163-193
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    • 2010
  • A Korean fairy tale, "I live on my fortune" is discussed and interpreted from the perspective of analytical psychology. Analytical psychology understands fairy tales are stories in which the workings of archetypes of unconsciousness are represented symbolically. Therefore they are intended to achieve psychic wholeness compensating collective consciousness. The fairy tale is found in almost every region of Korea. There are several parallel stories that share similar motifs, such as Samgongbonpoori, a mythological story and a tale on the king Mooh. The father in the story asked his three daughters whose fortune they lived on. The youngest was expelled by her father for she answered, "I live on my own fortune." Then she came into a humble cottage in the mountain marrying a poor charcoal maker and she found gold there. She became rich, made the charcoal maker a decent learned man and seeked for and took care of her parents who had become beggars. This fairy tale is interpreted as a story about individuation process of a woman who integrated 'inferior' aspects and unconscious animus through actively accepting the suffering from being expelled and commitment to the unconscious world, and also about how rigid collective psyche, under patriarchal system, changes toward wholeness through the workings of the unconscious.

The Effect of the Discontinuity Spacing/Length Ratio on Step-Path Failure of Jointed Rock Slopes (절리 암반 사면의 계단 경로 파괴에 미치는 불연속면 간격/길이 비의 영향)

  • Woon Sang Yoon
    • The Journal of Engineering Geology
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    • v.34 no.2
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    • pp.317-327
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    • 2024
  • When a non-persistent joint system is formed in a large-scale rock slope, slope failure may occur due to presence of a the stepped sliding surface. Such a surface can be divided into joint-to-joint sliding surfaces or joint-to-rock bridge sliding surfaces. In the latter case, the rock bridge provides shear resistance parallel to the joint and tensile resistance perpendicular to the joint. The load of the sliding rock can lead to failure of the rock bridge, thereby connecting the two joints at each ends of the bridge and resulting in step-path failure of the slope. If each rock bridge on a slope has the same length, the tensile strength is lower than the shear strength, resulting in the rock bridges oriented perpendicular to the joint being more prone to failure. In addition, the smaller the ratio of discontinuity spacing to length, the greater the likelihood of step-path failure. To assess the risk of stepped sliding on a rock slope with non-persistent joints, stability analysis can be performed using limit equilibrium analysis or numerical analysis. This involves constructing a step-path failure surface through a systematic discontinuity survey and analysis.

A Study on Implementation and Performance of the Power Control High Power Amplifier for Satellite Mobile Communication System (위성통신용 전력제어 고출력증폭기의 구현 및 성능평가에 관한 연구)

  • 전중성;김동일;배정철
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.1
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    • pp.77-88
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    • 2000
  • In this paper, the 3-mode variable gain high power amplifier for a transmitter of INMARSAT-B operating at L-band(1626.5-1646.5 MHz) was developed. This SSPA can amplify 42 dBm in high power mode, 38 dBm in medium power mode and 36 dBm in low power mode for INMARSAT-B. The allowable errol sets +1 dBm as the upper limit and -2 dBm as the lower limit, respectively. To simplify the fabrication process, the whole system is designed by two parts composed of a driving amplifier and a high power amplifier. The HP's MGA-64135 and Motorola's MRF-6401 were used for driving amplifier, and the ERICSSON's PTE-10114 and PTF-10021 for the high power amplifier. The SSPA was fabricated by the RP circuits, the temperature compensation circuits and 3-mode variable gain control circuits and 20 dB parallel coupled-line directional coupler in aluminum housing. In addition, the gain control method was proposed by digital attenuator for 3-mode amplifier. Then il has been experimentally verified that the gain is controlled for single tone signal as well as two tone signals. In this case, the SSPA detects the output power by 20 dB parallel coupled-line directional coupler and phase non-splitter amplifier. The realized SSPA has 41.6 dB, 37.6 dB and 33.2 dB for small signal gain within 20 MHz bandwidth, and the VSWR of input and output port is less than 1.3:1. The minimum value of the 1 dB compression point gets more than 12 dBm for 3-mode variable gain high power amplifier. A typical two tone intermodulation point has 36.5 dBc maximum which is single carrier backed off 3 dB from 1 dB compression point. The maximum output power of 43 dBm was achieved at the 1636.5 MHz. These results reveal a high power of 20 Watt, which was the design target.

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Depositional Characteristics and Seasonal Change of Surface Sediment and Sedimentary Strucutre on the Doowoovi Tidal Flat, Southwestern Coast of Korea (한국 서남해안 두우리 조간대에서 표층 퇴적물 및 퇴적구조의 특성과 계절변화)

  • Baek Young Suk;Chun Seungsoo
    • The Korean Journal of Petroleum Geology
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    • v.10 no.1_2 s.11
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    • pp.10-17
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    • 2004
  • The Doowoo-ri tidal flat in the southwestern Korean coast is a typical open-coast tidal flat which has no barriers in the offshore such as barrier island and sand bars. The difference of induced wave energy with seasons is affected directly on the distribution of surface sediment and the formation of sedimentary structures because the sedimentation by wind wave is relatively much important element in this open-coast tidal flat. This open-coast tidal flat can be classified into tidal beach, intertidal flat and lower mudflat according to the pattern of geomorphology and sediment type. The intertidal flat can be again divided into 3 types: sand flat, mixed flat and mud flat based on the primary sedimentary structure and sand/mud ratio. Doowoori tidal flat shows a seasonal change in the surface sedimentary facies based on sediment composition and primary sedimentary structure. The change is closely related to the direction and magnitude of monsoon wind and also to storm frequency. In winter and spring, when northwesterly wind is most dominant and strong and also storms are common, sand-flat facies is largely distributed on the intertidal flat, whereas mud-flat facies is most dominant during summer when weak southeasterly wind is common. In the fall season, mixed-flat facies is dominant on the flat. The Doowoori intertidal flat is covered by mud sediment which is ca. 20 cm in thickness in summer season. In winter season, surface sediment is changed from mud to sand because the summer mud is mostly eroded by strong wave action. Can-core peels in the intertidal flat show that parallel laminated mud or sand/mud and climbing ripple cross-laminated sandy silt are dominant on the upper intertidal flat $(0-1.3 {\cal}km)$ during summer season. On the other hand, on lower intertidal flat $(1.7-2.3 {\cal}km)$, dominant sedimentary facies is homogeneous mud. In winter, it is changed into parallel laminated and ripple cross-laminated sand facies.

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Comparative Study on Nursing Education System of Korea and China (한.중 간호교육제도 및 교육과정 비교연구)

  • Moon, Heui-Ja;Kim, Kwang-Joo;Park, Shin-Ae;Kim, Il-Won;Park, Hua-Shun
    • Journal of East-West Nursing Research
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    • v.7 no.1
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    • pp.32-47
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    • 2002
  • This study is a descriptive comparative investigated one to analyze nursing education system and curriculum of Korea and China trans-culturally. 1) Education System The basic level of nursing education in Korea consisted of 65 3-year- junior college of nursing (7379 students) and 48 4-year-bachelor of nursing college (2345 students) in 2000 showing more 3-year-junior college of nursing and its students. In China, western nursing as well as Chinese nursing education system were operating. In 2000, 501 western school of middle technical nursing, 29 school of middle technical nursing of middle level education, and 89 3-year western and 24 Chinese junior college of nursing, and 42 4-year western bachelor of nursing college and 10 Chinese of high level education have been established. The presence of Chinese school of middle technical nursing system seemed to be in slower development in nursing than Korea, but that of Chinese nursing education seemed to be advanced with its national identification prior to Korea. Post graduate continuous education for RN-Diploma and RN-BSN program has been opened as in Korea. The Hosa(護士) system in school of middle technical nursing in China reflects lower level of education than Korea. But it can be a merit, other than in Korea, without nurses aids, when they are acting under supervision of nurses and led by them, and there presents a special course for promotion up to high level education. Graduate school in Korea is divided into general type opening a curriculum for MS in 1960 and as of 2000, 21 general types for majoring in nursing. The PhD course in Korea was established in 1978, and after that the PhD courses have been opening in 14 universities at present. China established master degree course in 1991 and as of 7 colleges are ongoing, and the doctoral course is now under planning, resulting slower development than Korea. 2) Education of theory and clinical practice in Korea and Chine (1) Korea's 3-year junior nursing college have 51 subjects, 49 subjects in China, which was not different. China was following education of ideology and medical. 4-year Bachelor of Science College has 92 subjects in Korea with cultural subjects and essential major studies/elective in theory education in Korea, while 63 subjects in China, showed wider selection in Korea's education. (2) Korea's 3-year and 4-year nursing colleges performed clinical practice education parallel with theoretical education for a certain period, block or theory/practice system. While China's 3-year and 4 or 5-year-colleges educated the theory first and then practice for one year in the last grade, integrating each situation of the departments and the theory. (3) Korea's oriental nursing theory in nursing education was performed in 28 colleges of 65 nationwide ones of 3-year junior nursing colleges, but only one school was educating clinical practice. In 4-year bachelor of nursing colleges, the oriental nursing theory was done in 14 among 48 investigated. And 1-4 subjects of them were doing, and 4 schools performed of clinical practice, showing more reinforced than the junior colleges. China's 3-year and 4-5-year western nursing colleges taught two subjects of Chinese medicine nursing. China's 3-year & 4-5-year College of Chinese medicine nursing, theory of Chines medicine nursing education taught eight subjects. (4) 5-year colleges of Chinese medicine western integrated nursing, theory of Chinese medicine nursing education consisted of twelve Chinese medicine nursing subjects and two of Chinese medicine western integrated nursing subjects. China was tempting a new development of a pattern of Chinese medicine nursing subjects reinforced. 3) The verification of Korean and Chinese nurse's license. The verification test of Chinese nurses license is differentiated at the level of education other than in Korea. Expire date is 2 years and a qualified test must be done to a renewal. And the continuing education hours are 72 per year, which is more enforced than Korean nurses (10 hours a year). In accordance with WTO regulations, we should prepare for opening foreign hospital, educating oriental nursing subjects. And on this, it is recommendable to settle a basic frame research to run the oriental nursing practice ongoing. 1. It is desirable to develop the oriental nursing subjects to apply its idea to the western nursing and differentiate Korean nursing. 2. It is desirable to certify oriental nurse's characters, to expand and develop the nursing areas to practice it, and to establish the oriental nursing system. 3. It is expectable to promote Korean nursing specialization to develop the oriental nursing as a professional and to create its demand.

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