• Clinical and Experimental Reproductive Medicine
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• v.25 no.2
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• pp.115-122
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• 1998

The maintenance of a viable pregnancy has long been viewed as an immunological paradox. The deveolping embryo and trophoblast are immunologically foreign to the maternal immune system due to their maternally inherited genes products and tissue-specific differentiation antigens (Hill & Anderson, 1988). Therefore, speculation has arisen that spontaneous abortion may be caused by impaired maternal immune tolerance to the semiallogenic conceptus (Hill, 1990). Loss of recall antigen has been reported in immunosuppressed transplant recipients and is associated with graft survival (Muluk et al., 1991; Schulik et al., 1994). Progesterone $(10^{-5}M)$ has immunosuppressive capabilities (Szekeres-Bartho et al., 1985). Previous study showed that fertile women, but not women with unexplained recurrent abortion (URA), lose their immune response to recall antigens when pregnant (Bermas & Hill, 1997). Therefore, we hypothesized that immunosuppressive doses of progesterone may affect proliferative response of lymphocytes to trophoblast antigen and alloantigen. Proliferative responses using $^3H$-thymidine ($^3H$-TdR) incorporation of peripheral blood mononuclear cells (PBMCs) to the irradiated allogeneic periperal blood mononuclear cells as alloantigen, trophoblast extract and Flu as recall antigen, and PHA as mitogen were serially checked in 9 women who had experienced unexplained recurrent miscarriage. Progesterone vaginal suppositories (100mg b.i.d; Utrogestan, Organon) beginning 3 days after ovulation were given to 9 women with unexplained RSA who had prior evidence of Th1 immunity to trophoblast. We checked proliferation responses to conception cycle before and after progesterone supplementation once a week through the first 7 weeks of pregnancy. All patients of alloantigen and PHA had a positive proliferation response that occmed in the baseline phase. But 4 out of 9 patients (44.4%) of trophoblast antigen and Flu antigen had a positive proliferative response. The suppression of proliferation response to each antigen were started after proliferative phase and during pregnancy cycles. Our data demonstrated that since in vivo progesterone treated PBMCs suppressed more T-lymphocyte activation and $^3H$-TdR incorporation compare to PBMCs, which are not influenced by progesterone. This data suggested that it might be influenced by immunosuppressive effect of progesterone. In conclusion, progesterone may play an important immunological role in regulating local immune response in the fetal-placental unit. Furthermore, in the 9 women given progesterone during a conception cycle, Only two (22%) repeat pregnancy losses occured in these 9 women despite loss of antigen responsiveness (one chemical pregnancy loss and one loss at 8 weeks of growth which was karyotyped as a Trisomy 4). These finding suggested that pregnancy loss due to fetal aneuploidy is not associated with immunological phenomena.

• Korean Journal of Social Welfare
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• v.61 no.2
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• pp.161-187
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• 2009

Disability Discrimination Act(DDA) is generally recognized as the institutional frame to realize social model of disability. However social model is not automatically realized via the enactment of DDA. The realization of social model is influenced by various factors among which the definition of disability in DDA is very important factor. Paradoxically definitions of disability based on social model may push DDA into contradictory situation. This is caused by the fact that on the one hand definitions of based on social model exclude impairment and on the other hand they mixes characteristics and treatment. Because of these, when definitions of disability based on social model is reflected into definitions of disability in DDA, they may not be helpful to realize social model against original intention of advocates of the model. We can consider two approaches to resolve this paradox; one is to partially reform current definition of disability in DDA, the other is to totally amend current definition of disability. The former may pragmatic and worth to pursue but it cannot solve fundamental problems and may cause some new problems. The most consistent resolution with social model is to amend current definitions of disability into radically new one which excludes substantial limits and definition of disabled person from definition of disability. This new definition may called characteristics based definition or impairment based definition. Some people may think this new definition as one based on medical model but it is not. What we need is not to carve definition of disability based on social model into DDA but to make institutional frame for DDA to operate without contradictions and to develop social model of both impairment and disability. This model which does not exclude impairment could takes part in realization of the social model disability.

• Sijohaknonchong
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• v.42
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• pp.117-150
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• 2015

English sijo is the sijo poems written in English. This paper considered English sijo especially in association with its wit. In English-speaking countries, wit has been often emphasized as one of the main characteristics of the sijo genre, and it is often found in many English sijo poems. As a critical term, wit indicates a kind of "concord of discord", which consists of dissimilar images, paradox, irony, etc. This paper investigated how English sijo embodied this kind of critical wit and created three kinds of delight; those are intelligent, sarcastic, and humorous one. First, I examined old Korean sijo poems and the wit embedded in them, and then I compared them to the case of English sijo. Sijo was received in English-speaking countries in the context of the literary genre tradition such as the epigram and the sonnet, and of the literary concepts such as irony and wit. In this context, sijo, which has a three-divided semantic structure and a twist in the last part, often containing irony and wit, could be received and composed without much difficulty in Englih-speaking countries. Many English sijo poems contain wit, and they make abundant delight, which is intelligent, sarcastic, or humorous. Wit is found in Korean old sijo too, but the wit that catches humorous moments variously in everyday lives, rather than show acid sarcasm or exaggerated comic scene, is a remarkable characteristic of the English sijo. English sijo presents the possibility of the sijo genre as the poetry of everyday life, which presents various aspects of daily lives in a warm and delightful perspective.

• Sijohaknonchong
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• v.44
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• pp.255-279
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• 2016

Ignominy are ashamed or that mind. It is noted that this article 'shame[恥]' will do for obtaining the social dynamics in some way in the literary aspect. To investigate this aspect, this article took the text produced on the basis of 'shame[恥]' to be analyzed. First, through the Sayuksin[死六臣]'s Sijo[時調], 'Shame[恥]' they have confirmed the room to go to form a sympathy by revealing without hidden. It is worth evaluating in common with these Sijo is that of justice or loyalty. But the parameters of evaluation described what people are rare. In this article, I saw the parameter to 'shame[恥]'. Second, through the Sijo created in the war of the middle age of Chosun Dynasty, I examined the aspect of 'anger' which sparked a shame[恥]. Thus shame[恥] is hard to change the world directly. However, the possibility that it can also be a psychological instrument was found to be sufficient. In conclusion, 'shame[恥]' is clearly greater tendency to dismiss as a private act of the heart. But, I understood that the negative region of 'shame[恥]' can be converted to positive region. At this time, The premise of 'shame[恥]' should always be oriented to justice.

• Journal of Technology Innovation
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• v.28 no.1
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• pp.53-80
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• 2020

Recent studies focus on how open innovation strategies affect innovation in enterprises, but lack research related to the forms of openness. There is also a paradox that an entity should open up for open innovation but also protect its innovation. In this regard, the need for research on innovation protection has expanded. Therefore, this study looked at the effect of the form of openness on product innovation, and explored how the relationship between the form of openness and product innovation depends on the appropriation mechanisms. This study used data from the Korean Innovation Survey(KIS), which was developed and distributed by the OECD. The main findings of this study are summarized as follows. First, the forms of openness has a positive effect on product innovation. Specifically, external search has had a positive impact on exploitative innovation, and collaboration has shown to have a positive impact on exploratory innovation. Second, the appropriation mechanisms has a positive moderating effect on the relationship between the forms of openness and product innovation. Specifically, it was shown that formal appropriation mechanisms had a positive effect on the relationship between external search and product innovation, and that informal appropriation mechanisms had a positive effect on the relationship between collaboration and exploratory innovation. This study is expected to contribute to: First, this study has divided the forms of openness into external search and collaboration, unlike the existing method, and thus identified the type of product innovation and the appropriation mechanisms and forms of openness by identifying the impact on product innovation. Second, depending on the characteristics of the appropriation mechanisms, it was identified that it had the moderating effect on the forms of openness and the relationship of product innovation, so that depending on the type of openness and the type of product innovation, the type of appropriation mechanisms more suitable was identified.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.2
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• pp.422-429
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• 2007

Location awareness is one of the key functionalities to build an U-city. Recently, many of works of the location-aware systems are emerging to commercially apply to on-going large-scale apartment complex based on U-city. As dwellers or cars being attached with active tags are moving in the U-city complex, the active tags periodically broadcast their own identifiers and receivers fixed along the street or in building use those information to calculate location of them. There are several issues to be considered for such an environment. The first is that the number of active tags operating in the same region are large as much as tens of thousands, and the second is that the active tags should be alive without change of batteries more than a year, hence low power consumption is very important. In this paper we propose i) a new architecture for location-aware system considering such issues, ii) technical issues to implement it using active tags, and iii) a mathematical analytic model to investigate overall performance and verify it by comparing with actual experimental results. Through the analysis we can show the theoretical boundary of the lowest packet loss rate and the maximum number of tags with acceptable performance for the systems based on active tags. The results can be applied to practical design of location-based systems of U-City projects.

• Cross-Cultural Studies
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• v.20
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• pp.241-274
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• 2010

Due to the remarkable changes in the early twentieth century, the new invention and technology impacted peoples' everyday lives and people started to use the word, modern, to apply specifically to what pertained to present times and to designate a movement in what was new and not old-fashioned-a condition of newness. In the present day, however, the fantastic cultural changes of a century ago have now become commonplace, and what was once considered radically new is no longer a reason to marvel. This paper considers what it mean to be modern, once the new is no longer new. This question seems to remain as complicated and inappropriate to ponder because the consideration and impact of modernity cannot simply end with the end of an era. This paper investigates how the interconnected nature of popular culture provides apt illustrations to reveal the ambivalent nature of modernity and postmodernity. In doing so, first of all, this paper pays attentions to the notion of modernity and popular culture which emerged together in the early twentieth century when technology and mass consumer culture were promoted over the world. Also, it examines how popular culture represents a complex of mutually-interdependent perspectives and values that influence society and its institutions in various ways as the image of modernity continues to build in a postmodern era. That is, popular culture is identified as a large amount of intertextuality or collective experiences due to its intermingling of complementary distribution sources and techonology. Thus, this paper explores that popular culture devotes itself other images or narratives instead of referring to the real world and its output revisits the contemporary or past times in other places, being a means to produce and reproduce the accumulated images of the modern which shapes ceaseless simulacra of modernity over complexities of modernity. In order to find a critical juncture of the complex networks of modernity and popular culture, this paper considers two places, Chicago and Gyeongsung in the 1920s and 1930s in which the rapid modern experience took place and the modern movement forced the two societies to join the mass consumer culture whether willingly or not. Next, this paper considers two movies released in 2002 and 2008 that exemplify the complexities of modernity in Chicago and Gyeongung of the 1920s and 30s: Chicago and Modern Boy. Both films have common themes of the 1920s and 30s such as violence, adultery, femme fatal, and criminal themes with the forms of musical, dance, drama, and romance. Through the textual analysis of both Chicago and Modern Boy, two films are compared in observing the similar and different ways in which two films deal with the theme of modernity when they are represented from the contemporary perspectives. More specifically, this paper questions how modernity is present in contemporary cultural forms such as commercial and hybrid genre films; and how these movies create a new image of modern by embodying the double coding. Ultimately, this paper aims at realizing the paradox of double edged modernity and its ongoing discourse that controls people's consciousness through the medium of popular culture.

• Korean Journal of Logic
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• v.22 no.1
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• pp.43-86
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• 2019

If 1st order ZFC is consistent(has a model($M_1$)) it has a transitive denumerable model($M_2$). This leads to a paradoxical situation called 'Skolem paradox'. This can be easily resolved by Skolem's typical resolution. but In the process, we must accept the model theoretic relativity for the concept of set. This relativity can generate a situation where the meaning of the set concept, for example, is given differently depending on the two models. The problem is next. because the sentence '¬denu(PN)' which indicate that PN is not denumerable is equally true in two models, A indistinguishability problem that the concept <¬denu> is not formally indistinguishable in ZFC arise. First, I will give a detail analysis of what the nature of this problem is. And I will provide three ways of responding to this problem from the standpoint of supporting ZFC. First, I will argue that <¬denu> concept, which can be relative to the different models, can be 'almost' distinguished in ZFC by using the formalization of model theory in ZFC. Second, I will show that <¬denu> can change its meaning intrinsically or naturally, by its contextual dependency from the semantic considerations about quantifier that plays a key role in the relativity of <¬denu>. Thus, I will show the model-relative meaning change of <¬denu> concept is a natural phenomenon external to the language, not a matter of responsible for ZFC.

• 한국사회정책
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• v.25 no.3
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• pp.3-35
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• 2018

This article critically reviews the arguments that deny the financial feasbility and effectiveness of universal basic income as an alternative to existing social security systems and makes some suggestions to design effective and efficient basic income schemes. Regarding the financial feasibility of universal basic income, I argue that replacement of the existing regressive tax expenditures with universal basic income without raising tax rates can effectively reduce tax burden or provide income support to a majority of people except the rich. Addition of basic income to the tax base and reduction of the number of beneficiaries of public assistance and the amount of cash payment for them can further help save money. Regarding the redistributive effect, I note that the targeting ability of the existing social security systems is not good and that "the paradox of redistribution" that universal-type programs tend to be more redistributive than selective programs applies to universal basic income as well. I demonstrate significant redistributive effect of a hypothetical revenue-neutral basic income scheme and reviews several empirical studies done in Korea and abroad to show that basic income can be more effective in redistribution than social insurances or public assistance programs. Lastly, I emphasize the need to construct a reliable tax-benefit microsimulation model to help researchers to study redistributive effects of basic income schemes and other taxes and social policies.

• Cross-Cultural Studies
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• v.52
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• pp.1-29
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• 2018

The notion of 'gift' is one of the effective and fruitful codes for understanding Western civilization. In this study, we will shed light on several meanings, especially by comparing among the three French philosophers that expressed interest in this notion: they are Mauss, Derrida and $Ric{\oe}ur$. Called "father of French ethnography", Mauss claims, in his famous article "Essay on the Gift", that the gift is paradoxically a kind of economic exchange dominated by three obligations: to give, receive, and return. But he strives to establish a moral theory based on the obligation to give. Under the influence of Mauss, Derrida deconstructs the theory of Mauss by devoting attention to 'time', one of the determining elements in studies on the gift. Derrida observes that the gift is established just at the extremely short moment of emergence of the act of giving and that this act is transformed into an economic exchange with passing of time. From it, the impossibility of the gift is derived despite its concrete and real emergence and existence. Under the influence of Mauss, $Ric{\oe}ur$, for his part, is interested in the notion of giving as part of the dialectic between 'love' and 'justice'. According to him, whereas justice is dominated by the economy of gift, namely the logic of equivalence, love, by the logic of 'superabundance'. He focuses on establishing 'Supra-ethics' by considering the fact that the gift is at the core of his religious and philosophical vision. Finally, let us point out that in $Ric{\oe}ur$, this notion of gift ('don') is closely linked to forgiveness ('pardon'), that holds in it the secret of understanding regarding the 'fallible' and 'capable' man.