• Title/Summary/Keyword: palatinose syrup

Search Result 2, Processing Time 0.02 seconds

Acute Toxicity of Palatinose and Palatinose Syrup in Rats (팔라티노스 및 팔라티노스 시럽의 Rat 에서 급성 독성)

  • Lim, Dong-Moon;Lee, Seong-Hak;Kim, Dal-Hyun;Cho, Hyo-Jin;Kim, Jeong-Hwan;Chun, Young-Jung;Kim, Je-Hak
    • Korean Journal of Food Science and Technology
    • /
    • v.29 no.4
    • /
    • pp.800-803
    • /
    • 1997
  • The acute toxicity of palatinose and palatinose syrup was assessed in Sprague-Dawley rats. Palatinose and palatinose syrup, when administered orally at the doses of 27 g/kg, did not cause any death. Although the decrease in weight gain was observed in males treated with palatinose syrup, it did not have any toxicological importance. There were no significant changes in hematological and biochemical parameters. From these results, it was concluded that palatinose and palatinose syrup did not induce any remarkable toxicological symptoms and the $LD_{50}$ is >27 g/kg by oral administration in Sprague-Dawley rats.

  • PDF

In Vitro Mutagenicity Tests on Palatinose and Palatinose Syrup (팔라티노스 및 팔라티노스 시럽에 대한 in vitro 변이원성 시험)

  • Baek, Nam-Jin;Kang, Jae-Ku;Kim, Jeong-Hwan;Kim, Dal-Hyun;Chun, Young-Jung;Kim, Je-Hak
    • Korean Journal of Food Science and Technology
    • /
    • v.29 no.4
    • /
    • pp.804-807
    • /
    • 1997
  • Palatinose is a disaccharide molecule which can substitute sucrose as a sweetening agent. A microbial fermentation technology has been developed to produce palatinose. In order to verify the safety of palatinose products, we have performed 1) bacterial reverse mutation test using Salmonella typhimurium TA1535, TA1537, TA98 and TA100, and 2) in vitro chromosome aberration test using Chinese Hamster Lung (CHL) cell. In bacterial reverse mutation test, both palatinose and palatinose syrup did not induce any significant increase of $His^{+}$ revertants up to 10 mg/plate. In in vitro chromosome aberration test, palatinose and palatinose syrup also did not cause any significant increase of chromosome aberrant cells up to 5 mg/mL. These results suggest that palatinose products have no mutagenic potential in these in vitro mutagenicity tests.

  • PDF