• Journal of Plant Biology
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• v.37 no.3
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• pp.263-269
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• 1994

Involvement of ethylene and Ca2+ on the induction of phenylalanine ammonia-lyase (PAL) was investigated in Daucus carota L. suspension culture system. Ethylene production started to increase about 3 h after glucan treatment. And the maximal induction of ethylene was preceded by PAL induction by 30 min. After the treatment of ethrel, PAL activity was increased. When cells were treated with glucan and Co2+, PAL activity was simultaneously reduced. Ethylene production was reduced dramatically in calcium-free medium, even though glucan was treated. PAL activity and ethylene producton was inhibited conspicuously when ethylene glycolbis($\beta$-aminoethyl ether) N,N,N',N'-tetraacetic acid (EGTA) was treated with glucan. Verapamil and trifluoperazine also inhibited PAL activity. When cells were treated with calcium ionophore A23187, PAL activity was increased in nontreated medium. We report here PAl activity is increased in related to ethylene production and involvement of Ca2+ in glucan-treated carrot suspension cells.

• Archives of Plastic Surgery
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• v.32 no.4
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• pp.496-502
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• 2005

This study was performed to compare the effect of external ultrasound assisted PAL(power assisted liposuction) with that of PAL alone. We performed 17 cases of liposuction from January 2003 to June 2003. For comparing both systems, we treated the right side(study group) with external ultrasound assisted PAL and the left side(control group) with PAL alone. To evaluate the difference in results between two groups, we surveyed three objective and four subjective items. Objectives were categorized as "Reduction rate of postoperative swelling", "Efficiency of suction" and "Histologic finding of aspirated fat tissue". Subjectives were also filed as "Degree of postoperative bruising", "Cannula resistance that operator felt", "Degree of postoperative pain" and "Patient's satisfaction". We assessed by questionnaire three times at 1day, 7 days and 30 days after operation. There were statistically significant differences in two of the subjective items; "Degree of postoperative pain at postoperative 1 day" and "Cannula resistance that operator felt". This study concludes that external ultrasound PAL is more effective high mobility of fat tissue and low tension of surrounding tissue. External ultrasound PAL will be more useful in case of large volume liposuction and revision procedures.

• Proceedings of the Korean Vacuum Society Conference
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• 2009.08a
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• pp.335-335
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• 2009

• Food Science and Biotechnology
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• v.18 no.4
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• pp.954-958
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• 2009

Effects of controlled- and uncontrolled-pH operations on phenylalanine ammonia lyase (PAL) production by a recombinant Escherichia coli strain were investigated at uncontrolled-pH ($pH_{UC}$) and controlled-pH ($pH_C$) of 5.5, 6.0, 6.5, 7.0, 7.5, 8.0, and 8.5 in bioreactor systems. The results showed that the recombinant PAL activity was improved significantly by controlled pH strategy. Among the $pH_C$ operations, the highest PAL activities were obtained under $pH_C$ 7.5 strategy where cell mass ($OD_{600\;nm}$) and PAL activity was 1.3 and 1.8 fold higher than those of $pH_{UC}$, respectively. The maximum PAL activity reached 123 U/g. The $pH_C$ 7.5 strategy made recombinant plasmid more stable and therefore allowed easier expression of PAL recombinant plasmid, which increased PAL production. It was indicated that the new approach (controlled-pH strategy) obtained in this work possessed a high potential for the industrial production of PAL, especially in the biosynthesis of L-phenylalanine.

• Journal of Korean Medical classics
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• v.10
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• pp.671-728
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• 1997

By studying from Chun Kuk are(戰國時代) to Chung area(淸代), I could find some conclusion as follows. 1. It was Chun Kuk area(戰國時代) that was shown some signs of forthcoming activity of theory of Ki Kyung Pal Maek(奇經八脈). In that time, Hwang Jae Nae Kyung(黃帝內經) had been written. That book made a important role for foundation of theory of Ki Kyung Pal Maek(奇經八脈), but it hadn't sufficient contents in some parts. 2. The theory of the Ki Kyung Pal Maek (奇經八脈) had been developed in Jin Han area(秦漢時代), Nan Kyung(難經) had been written in the area, Nan Kyung(難經) had been the first book which had referred to name and physiology of Ki Kyung Pal Maek(奇經八脈) and it also had mentioned about course, function, and pathology of that in simple manner. 3. In Yang Jin are and Su Dang area(兩晋 및 隋唐時代), Maek Kyung(脈經) and Hwang Jae Nae Kyung Tae So(黃帝內經太素) had been written Maek Kyung(脈經) had been the first book which had referred to pathology of Ki Kyung Pal Maek(奇經八脈) by Maek Jin(脈診) in detail, and it had affected on such books like Tae Pyung Seoung Hveu bang (太平聖惠方) and Ko Kum Yeu Tong Dae Chon(古今醫統大全). Hwang Jae Nae Kyung Tae So(黃帝內經太素) had mentioned about course, function, and pathology about Ki Kyung Pal Maek(奇經八脈) in most detail at that time, and it also had referred to that of such books like Myung Dang(明堂) and Ku Khoun Kyung(九卷經) which do not exist in present. Because of these point, Hwang jae Nae Kyung Tae So(黃帝內經太素) is evaluated an important book of theory of Ki Kyung Pal Maek(奇經八脈). 4. In Song area(宋代), Seung Jae Chong Rok(聖濟總錄) had been written. Seung Jae Chong Rok(聖濟總錄) first mentioned about meeting between Ki Kyung Pal Maek(奇經八脈) and Sip I Jong Kyung(十二正經), so this book helped development of theory of Ki Kyung Pal Maek(奇經八脈) of Kum Won area(金元時代). 5. In Kum Won area(金元時代), Dong In Su Hyul Chym Ku Do Kyung(銅人腧穴針灸圖經) had been written. Dong In Su Hyul Chym Ku Do Kyung(銅人腧穴針灸圖經) made a important role of theroy of Im Meak(任脈) and Dok Meank(督脈). Sip Sa Kyung Bal Hyui(十四經發揮) was superior to other books which had been referred to theory of Ki Kyung Pal Maek(奇經八脈) at that time. Also Sip Sa Kyung Bal Hyui(十四經發揮) more mentioned about meeting between Ki Kyung Pal Maek(奇經八脈) and Sip I Jong Kyung(十二正經) than that of Seung Jae Chong Rok(聖濟總錄), so this book helped dvelopment of theory of Ki Kyung Pal Maek(奇經八脈). 6. In Myung area(明代), Ki Kyung Pal Maek Ko(奇經八脈考) that had almost accomplished theory of Ki Kyung Pal Maek(奇經八脈) had been written. Ki Kyung Pal Maek Ko(奇經八脈考) was the best book more than any other book that had been mentioned about theory of Ki Kyung Pal Maek(奇經八脈) in three ways as follows. 1) It is Ki Kyung Pal Maek Ko(奇經八脈考) that mentioned about near similar manner of modern course and physiology of Ki Kyung Pal Maek(奇經八脈). 2) Ki Kyung Pal Maek Ko(奇經八脈考) mentioned about pathology and treatment of Ki Kyung Pal Maek(奇經八脈) in detail more than any other book. 3) Ki Kyung Pal Maek Ko(奇經八脈考) emphasized on relationship between Ryun Kong(鍊功) and Ki Kyung Pal Maek(奇經八脈).

• Korean Medical Education Review
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• v.18 no.2
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• pp.106-113
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• 2016

The purpose of this study is to identify factors associated with effective peer-assisted learning (PAL) for nursing students. This review examined studies on PAL in nursing education. The literature was searched using terms including 'nursing & peer assisted learning,' 'nursing & peer learning,' and 'nursing & peer teaching.' Potentially relevant research on PAL was identified, and 12 studies were determined to meet the inclusion criteria. This review includes five qualitative, three mixed-methods, and three experimental studies published on the topic. In the studies reviewed, practicum classes were found to use PAL the most. Students of the same age were most commonly the subjects of PAL, as indicated in six papers. PAL has been suggested to affect participants' knowledge, self-efficacy, confidence, and anxiety. The findings indicate that interactions between peers promote learning and lead to mutually positive responses, which provide opportunities for self-development. Finally, students' learning outcomes improve and their confidence in their knowledge and skills increases as they experience the role of student nurse. These findings indicate that PAL can be utilized as an efficient learning method in nursing education programs. However, effective strategies for using PAL to achieve learning objectives and maximize learning outcomes are needed.

• Biomolecules & Therapeutics
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• v.22 no.4
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• pp.321-327
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• 2014

Collagen pentapeptide (Lys-Thr-Thr-Lys-Ser, KTTKS) and its palmitoylated derivative (pal-KTTKS) have received a great deal of attention as cosmeceutical ingredients for their anti-wrinkle effects. The objective of this study was to evaluate stability and permeability of KTTKS and pal-KTTKS in hairless mouse skin. In this study, a liquid chromatography-tandem mass spectrometric method was developed for the quantification of pal-KTTKS, and used for stability and permeability studies. Stability studies were performed using skin extracts and homogenates. Both KTTKS and pal-KTTKS were rapidly degraded, but pal-KTTKS was more stable than KTTKS. When protease inhibitors were added, the stability of both compounds (KTTKS and pal-KTTKS) improved significantly. In the skin permeation study, neither KTTKS nor pal-KTTKS was detected in the receptor solution, which indicates that neither compound could permeate through the full-thickness hairless mouse skin in the experimental conditions of this study. While KTTKS was not detected in any of the skin layers (the stratum corneum, epidermis, and dermis), pal-KTTKS was observed in all skin layers: $4.2{\pm}0.7{\mu}g/cm^2$ in the stratum corneum, $2.8{\pm}0.5{\mu}g/cm^2$ in the epidermis, and $0.3{\pm}0.1{\mu}g/cm^2$ in the dermis. In conclusion, this study indicated that pal-KTTKS had greater stability and permeability than that of un-modified KTTKS, and may be a useful anti-wrinkle and anti-aging cosmeceutical agent.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.7
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• pp.1006-1012
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• 2017

Objective: This study was conducted to investigate effects of zinc (Zn) bearing palygorskite (ZnPal) supplementation on growth performance, hepatic mineral content, and antioxidant status of broilers at early age. Methods: A total of 240 1-day-old Arbor Acres broiler chicks were allocated into 5 treatments with 6 replicates of 8 chicks each. Birds in 5 treatments were fed a basal diet supplemented with 0 (Control group; Analyzed Zn content: 81 mg/kg), 20, 40, 60, and 80 mg/kg Zn as ZnPal for 21 days, respectively. Blood, liver and intestinal mucosa were collected at 21 days of age. Results: Treatments did not affect growth performance of broilers during the 21-day study (p>0.05). The contents of hepatic Zn and magnesium (Mg) were linearly increased (p<0.001) by ZnPal supplementation. ZnPal inclusion linearly (p = 0.007) reduced malondialdehyde (MDA) concentration in serum. The activity of total superoxide dismutase (T-SOD) in liver increased linearly (p = 0.001) with concentration of ZnPal in diet. ZnPal inclusion linearly (p = 0.036) and quadratically (p = 0.005) increased T-SOD activity, and linearly (p = 0.012) increased copper/zinc superoxide dismutase (Cu/Zn SOD) activity in jejunal mucosa. The maximum responses of hepatic and jejunal antioxidant enzymes activities (T-SOD and Cu/Zn SOD) were found when supplementing the basal diet with 60 mg/kg Zn as ZnPal. Furthermore, ZnPal supplementation quadratically (p = 0.001) increased Cu/Zn SOD activity in ileal mucosa, and its maximum activity was observed in the diet supplemented with 20 mg/kg Zn as ZnPal. Conclusion: ZnPal supplementation did not alter growth performance of broilers. Dietary ZnPal inclusion could increase concentrations of hepatic trace minerals (Zn and Mg) and inhibit lipid peroxidation by reducing serum MDA accumulation, with the optimal dosage of Zn from ZnPal being 80 mg/kg diet (analyzed Zn content in the diet: 165 mg/kg), and 60 mg/kg Zn as ZnPal (analyzed Zn content in the diet: 148 mg/kg) was the optimum dosage for broilers to achieve maximum antioxidant enzyme activities.

• International Journal of Contents
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• v.15 no.3
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• pp.39-46
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• 2019

This study aimed to develop a peer-assisted learning (PAL) program for use in a core nursing skills education course and to investigate the effects of the education program on three key outcomes. A comparative study was conducted through the division of students of a core nursing skills education program into a treatment group and control group. After the programs, self-efficacy, confidence and satisfaction were compared between the groups. The comparison of these three factors indicated that the related scores were significantly higher in the treatment group receiving the education program with the PAL method than those of the control group receiving traditional education. We concluded that self-efficacy gave the nursing students the confidence that they could successfully perform their tasks and motivation to learn. Education programs using the PAL method are suggested as an effective method for the acquisition of skills among nursing students.

• Proceedings of the KIEE Conference
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• summer
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• pp.1190-1192
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• 2004

풍력을 이용한 풍력발전기의 전력변환 시스템을 개발하기 위해서는 바람특성을 정확히 분석하고 이를 대치할 수 있는 모의시험 장치가 필수적이다. 모의시험 장치는 풍향, 풍속 등의 인자들을 입력받아 회전 블레이드의 토오크를 전동기가 대신해서 발전기에 공급하게 된다. 본 논문에서는 풍력발전 모의시험 장치를 이용해서 현재 개발 중인 750kW gearless형 풍력발전 시스템의 인버터 특성과 고효율의 전력변환 설계를 위해 시험용 지그에서 시험한 결과를 보이고자 한다.