• Asian-Australasian Journal of Animal Sciences
• /
• 제6권1호
• /
• pp.67-72
• /
• 1993

Three sheep fitted with cannulas in the rumen and the caecum were used in a $3{\times}3$ Latin square design to study the changes in ruminal and caecal microbial populations and their metabolite composition with ammoniated rice straw feeding. The 3 diets contained either 80% untreated rice straw (UTS) or ammoniated rice straw (ATS) and 20% formula feed. These were a control diet (C), a urea supplemented diet (U) containing urea at 1.1% and an ammoniated rice straw diet (AT). Data were analyzed by analysis of variance and means separated by the Student Neumann Kuel's multiple comparison. AT feeding increased ruminal bacterial counts, in particular cellulolytic bacterial counts (p < 0.05) which were 1.8, 2.4 and 7.0 (${\times}10^6/ml$ ruminal fluid) for C, U and AT, respectively. There was an increasing tendency (p < 0.10) in ruminal fungal population with U; values were 2.0, 5.2, 3.1 (${\times}10^3/ml$ ruminal fluid) for C, U and AT, respectively. Ruminal protozoa counts were not significantly (p > 0.05) altered with diets. Caecal total viable bacterial count with AT was about thrice the value with C. Total VFA concentration in the rumen was significantly increased (p < 0.025) (7.7 mmol/dl for C and 8.2 mmol/dl for AT) and correspondingly, pH lowered when AT was fed. Sheep on AT tended to produce less acetate and more butyrate in the rumen without significance (p > 0.05). Similar to the rumen, total VFA concentrations of 4.4, 3.8 and 5.2 mmol/dl were detected, respectively, for C, U and AT. Caecal ammonia-nitrogen concentrations were about six-fold of that in the rumen, though there were no differences (p > 0.05) among treatments.

• 한국응용과학기술학회지
• /
• 제38권2호
• /
• pp.343-355
• /
• 2021

이 연구의 목적은 소득에 따른 베이커리 제품 구매 속성과 형태에 대해서 조사하였으며, 일반적인 사항에서 전체 1,235명 중에서 여성이 59.6%, 남성이 40.4%로 여성이 남성보다 다소 많았다. 베이커리 제품 구매 속성에서 '건강관심형'이 40.0%로 가장 많았고, 거주지에서는 대도시 거주자가 '맛 관심형'이 35.8%인 반면에 중소도시 거주자는 '건강 관심형'(p<0.001)의 45.4%로(p<0.001), 소득이 높을수록 건강에 대한 관심이 높았다(p<0.001). 베이커리 제품을 구매하는 소비자들은 '맛' 67.1%, '영양' 13.7%, '가격' 7.8% 순으로 거주지에 따라 유의한 차이를 나타내었다(p<0.01). 베이커리 이용형태에서는 프랜차이즈 베이커리가 71.1%, 윈도우 베이커리 14.6%, 인스토어 베이커리 8.4%였다.

• Journal of Korean Neurosurgical Society
• /
• 제67권2호
• /
• pp.227-236
• /
• 2024

Objective : Numerous studies have indicated that early decompressive craniectomy (DC) for patients with major infarction can be life-saving and enhance neurological outcomes. However, most of these studies were conducted by neurologists before the advent of intra-arterial thrombectomy (IA-Tx). This study aims to determine whether neurological status significantly impacts the final clinical outcome of patients who underwent DC following IA-Tx in major infarction. Methods : This analysis included 67 patients with major anterior circulation major infarction who underwent DC after IA-Tx, with or without intravenous tissue plasminogen activator. We retrospectively reviewed the medical records, radiological findings, and compared the neurological outcomes based on the "surgical time window" and neurological status at the time of surgery. Results : For patients treated with DC following IA-Tx, a Glasgow coma scale (GCS) score of 7 was the lowest score correlated with a favorable outcome (p=0.013). Favorable outcomes were significantly associated with successful recanalization after IA-Tx (p=0.001) and perfusion/diffusion (P/D)-mismatch evident on magnetic resonance imaging performed immediately prior to IA-Tx (p=0.007). However, the surgical time window (within 36 hours, p=0.389; within 48 hours, p=0.283) did not correlate with neurological outcomes. Conclusion : To date, early DC surgery after major infarction is crucial for patient outcomes. However, this study suggests that the indication for DC following IA-Tx should include neurological status (GCS ≤7), as some patients treated with early DC without considering the neurological status may undergo unnecessary surgery. Recanalization of the occluded vessel and P/D-mismatch are important for long-term neurological outcomes.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권23호
• /
• pp.10277-10280
• /
• 2015

Background and Aim: Breast cancer (BC) is a heterogeneous disease and cell proliferation markers may help to identify subtypes of clinical interest. We here analyzed the correlation between cell proliferation determined by Ki67 and HG in BC patients undergoing preoperative chemotherapy (PCT). Materials and Methods: We obtained clinical/pathological data from patients with invasive BC treated at our institution from 1999 until 2012. Expression of estrogen receptor (ER), progesterone receptor (PR), epidermal growth factor receptor type 2 (HER2) and Ki67 were determined by immuno-histochemistry (IHC). Clinicopathological subtypes were defined as: Luminal A, ER and/or PR positive, HER2 negative, HG 1 or 2; Luminal B, ER and/or PR positive, HER2 negative or positive and/or HG 3; triple negative (TN), ER, PR and HER2 negative independent of HG; HER2 positive, ER, PR negative and HER2 positive, independent of HG. By using Ki67, a value of 14% separated Luminal A and B tumors, independently of the histological grade. We analyzed correlations between Ki67 and HG, to define BC subtypes and their predictive value for response to PCT. Results: 1,560 BC patients were treated in the period, 147 receiving PCT (9.5%). Some 57 had sufficient clinicopathological information to be included in the study. Median age was 52 years (26-72), with 87.7% invasive ductal carcinomas (n=50). We performed IHC for Ki67 in 40 core biopsies and 50 surgical biopsies, 37 paired samples with Ki67 before and after chemotherapy being available. There was no significant correlation between Ki67 and HG (p=0.237), both categorizing patients into different subtypes. In most cases Ki67 decreased after PCT (65.8%). Only 3 patients had pathologic complete response (cPR). Conclusions: In our experience we did not find associations between Ki67 and HG. Determination of clinicopathological luminal subtypes differs by using Ki67 or HG.

• 한국산업보건학회지
• /
• 제25권4호
• /
• pp.506-515
• /
• 2015

Objectives: This study was conducted to evaluate the status of hazard communication regarding dental materials among dental hygienists in the Daegu Metropolitan City and the North Gyeongsang-do Province area. Materials: A total of 310 dental hygienists were surveyed using self-administered questionnaires to investigate the status of hazard communication on dental materials and information needs. We collected instructions for use and material safety data sheets(MSDSs) for 67 dental materials frequently used at dental hospitals located in the Daegu Metropolitan City and the North Gyeongsang-do Province area. Results: The questionnaire surveys showed that only 11% of the 310 dental hygienists had knowledge of MSDS and 46.8% of respondents never read instructions for use before using materials. Just 7.4% of dental hygienists have undergone training on hazard information for dental materials. In particular, dental hygienists working at dental clinics had significantly lower response rates on knowledge of MSDS(p<0.001), reading of instructions for use(p=0.042) and training on the hazard information of dental materials(p=0.004) than those in dental hospitals or general hospitals. The essential information most desired by dental hygienists was hazard identification(82.3%) followed by first-aid measures(53.9%), handling and storage(51%), disposal considerations (49%) and toxicological information(47.1%). All dental materials were on foreign products which came from Japan(59.7%), the USA(26.9%) and Liechtenstein(13.7%). In terms of usage, 56.7% of dental materials were prosthetic, followed by conservation(31.3%), orthodontics(9%), and prevention(3%). We found that dental hygienists had accessed MSDSs for only five dental products among the 67 dental materials. The instructions for the use of the 67 dental materials provided hazard identification(64.2%), first-aid measures(83.6%), handling and storage(97%), disposal considerations(20.9%) and toxicological information(26.9%). Conclusions: Based on the results of this study, the hazard communication system for dental hygienists working at dental clinics should be improved.

• 생물환경조절학회지
• /
• 제13권2호
• /
• pp.81-89
• /
• 2004

본 연구는 배지 구성물질로서 발포 유리질 소재(CGF)와 탄화 밤나무 목재입자(CCW)를 이용하여 배지를 재발하고 원예재배용 배지의 국산화를 위해 수행되었다. 토마토 종자는 발포 유리질 소재, 탄화 목재입자, 입상암면(GR), 그리고 피트모스를 혼합한 4종의 배지를 만들어 플러그 트레이에 충진하여 종자를 200구 플러그 트레이에 4반복으로 파종한 후 fog 번식상에서 3일간 발아시켰다. 발아 후 양지붕형 유리온실에 난괴법으로 배치하여 저면관수로 양액을 공급하여 육묘하였다. 상업적으로 이용되는 공정육묘 배지(토실이)를 대조구로 이용하였다. 플러그묘의 생육은 파종 후 31일째 측정하였다. 모든 처리에서 유사한 생육결과를 나타냈지만 특히 CCW(67%)+peatmoss(33%) 혼합배지에서 초장, 뿌리등급, 생체중, 그리고 배지의 기상과 가비중이 다른 처리에서보다 유의성 있게 좋았다. 모든 배지의 pH는 6.3∼7.4의 범위로 측정되었다. CGF와 입상암면의 혼합비율이 증가할수록 배지의 pH는 증가하였다. 재배 후 배지의 EC는 대조구에서 가장 높았으나 독성증상은 관찰되지 않았다. 엽수와 엽록소 함량은 처리간 유의성이 없었다.

• 문화기술의 융합
• /
• 제8권1호
• /
• pp.31-38
• /
• 2022

본 연구는 운동프로그램이 중기 노인(75~84세)의 악력과 균형능력에 미치는 효과를 확인하기 위하여 시도된 비동등성 대조군 전후설계를 이용한 유사 실험연구이다. 연구대상은 본 연구에 참여를 동의한 중기 노인(75~84세) 67명(실험군 33명, 대조군 34명)이다. 본 연구에서 수집된 자료는 SPSS 21.0 프로그램을 이용하여 빈도, 백분율, 카이제곱검정과 t-test로 분석하였다. 67명의 중기 노인들에게 주 2회, 60분씩 16주 운동프로그램을 제공한 결과 실험군의 악력과 균형능력이 대조군에 비해 유의하게 높게 나타났다. 본 연구를 통해 운동프로그램이 악력과 균형능력을 향상시켜 노인의 건강증진에 효과가 있음이 확인되었으므로, 지역사회 많은 노인들에게 운동프로그램을 적용하기 위해 노력해야 할 것이다. 본 연구 대상은 75세에서 84세까지의 중기 노인이었으므로 다양한 연령층의 노인들을 대상으로 하여 반복 연구를 실시 후 연령별 효과를 확인하고, 적어도 6개월 이상의 장기적인 프로그램을 실시하고 기간에 따른 운동의 효과를 평가하는 연구를 제언한다.

• 한국치위생학회지
• /
• 제8권4호
• /
• pp.165-180
• /
• 2008

The present study is a descriptive survey on factors affecting middle school students' oral health belief and oral health practice. In order to find methods for forming right beliefs and inducing desirable behavioral patterns, we conducted a questionnaire survey with 470 students at two middle schools in Cheongju and drew conclusions as follows. Of the 470 questionnaires, 457 were recovered. With 10 inappropriately answered ones excluded, 446 questionnaires were analyzed. 1. As to oral health belief according to general characteristics, susceptibility was 2.63 points (p=0.035) in male students, 2.68 (p=0.016) in 3rd year students, and 2.92 (p=0.002) in only child students. Seriousness was 2.57 (p=0.017) in male students, 2.67 (p=0.001) in 3rd?year students, and 2.92 (p=0.001) in only child students. barrier was 2.62 (p=0.009) in 3rd year students, and 2.95 (p=0.002) in only child students. Benefit was 3.40 (p=0.011) in female students, and 3.43 (p=0.003) in 1st year students. salience was 3.21 (p=0.006) in female students, and 3.24 (p=0.009) in 1st year students. 2. As to oral health belief according to oral?health?related factors, susceptibility and seriousness were 2.69 (p=0.003) and 2.72 (p=0.000), respectively, in the lower?middle class group, 2.83 (p=0.001) and 2.80 (p=0.003), respectively, in the drink taking group, and 2.80 (p=0.000) and 2.75 (p=0.000), respectively, in the low conversation group. barrier was 2.63 (p=0.018) in the lower?middle class group, 2.67 (p=0.021) in the low conversation group, and 2.77 (p=0.000) in the group fearing the visit to the dental clinic. Benefit was 3.36 (p=0.000) in the high conversation group, and 3.37 (p=0.0l5) in the group visiting the dental clinic for prevention. salience was 3.26 for beverage and 3.20 (p=0.003) for fruit and vegetable. 3. As to oral health practice according to general characteristics, the score of oral health practice was 3.21 (p=0.000) in female students, 3.30 (p=0.000) in those aged 12 or below, and 3.27 (p=0.000) in 1st?year students. 4. As to oral health practice according to factors related to oral health, the point was 3.17 (p=0.002) in the middle upper class group, 3.24 (p=0.001) in the group eating mainly fruit or vegetable, and 3.18 (p=0.030) in those with experience in education. 5. Oral health practice was in a negative correlation with susceptibility (r=-0.143), and in a positive correlation with benefit (r=0.229) and salience (r=0.286).

• Journal of Animal Science and Technology
• /
• 제54권2호
• /
• pp.125-131
• /
• 2012

본 시험은 산란계에 대한 맥섬석과 한방제재의 첨가급여가 계란의 생산성과 품질에 미치는 영향을 알아보기 위하여 산란초기에 있는 재래닭교잡종(재래닭${\times}$레드브로교잡종) 360수를 공시하여 4처리로 임의 배치하였다(각 처리구당 30수${\times}$3반복), 대조구(무첨가), 시험 1구(맥섬석 0.3% 첨가), 시험 2구(한방제재 0.3% 첨가), 시험 3구(맥섬석 0.3%+한방제재 0.3%)로 나누어 8주간 시험한 결과는 다음과 같다. 사료섭취량과 난중 및 평균 산란율은 처리구간에는 차이가 없었으나(P>0.05), 그러나 파란율은 대조구(3.41%)가 시험구보다 크게 높았으며, 그 중에서도 시험 3구가 가장 낮은 파란율을 나타내었다(P<0.05). 전란 중에서 조지방의 경우는 대조구(11.20%)가 시험구(9.67 - 10.01%) 보다 크게 높게 나타났다(P<0.05). 계란품질에서 호우유니트 계수, 난황색, 난각 두께 및 난각 강도는 시험구가 더 높은 경향을 보였으나 통계적인 유의차는 나타나지 않았다(P>0.05). 그러나 난각 강도는 시험구(36.98 - 37.52)가 대조구(35.56) 보다 유의적으로 높았고(p<0.05), 난황 중의 콜레스테롤 함량은 시험 3구(14.91 mg/g)가 다른 처리구보다 크게 낮았다(P<0.05). 지방산 조성에서 포화지방산 함량은 대조구가 시험구보다 더 높았으나, 불포화 지방산은 시험구(66.82 - 67.00%)가 대조구(64.58%) 보다 더 높게 나타났다(P<0.05). 결론적으로, 맥섬석과 한방제재 혼합첨가제는 난황중의 콜레스테롤 함량을 낮추고, 계란의 품질을 개선시킬 수 있을 것으로 사료된다.

• Nuclear Medicine and Molecular Imaging
• /
• 제43권1호
• /
• pp.26-34
• /
• 2009

목적: 원발성 위암 환자의 PET/CT 스캔에서 FDG 섭취에 영향을 주는 임상병리학적 및 면역조직화학적 지표들이 있는지 알아보고자 하였다. 대상 및 방법: 본원에 내원하여 수술 전 FDG PET/CT 스캔을 시행한 89명의 위암환자들을 대상으로 하였다. PET/CT 영상에서 원발 종양의 SUVmax를 구한 후 침범 깊이(T기),종양 크기, 림프절전이, 종양 분화, Lauren의 분류, Ki-67 지수, p53, EGFR, Cathepsin D, c-erb-B2. COX-2의 발현과 같은 임상병리학적 및 면역조직화학적 지표들과의 상관 관계를 분석하였다. 결과: 89예의 위암 중 19예에서는 PET/CT 영상에서 인지 가능한 FDG 섭취가 없었는데, 이 19예 중 16예는 원발 종양의 침범 깊이가 점막하 이내에 국한된 경우였다. 위암의 FDG섭취 정도는 T기가 T2 이상일 때가 T1일 때보다 유의하게 높았고($5.8{\pm}3.1$ vs. $3.7{\pm}2.1$, p=0.002), 위암의 크기가 3 cm 이상일 경우가 3 cm 미만일 경우보다 유의하게 높았다($5.7{\pm}3.2$ vs. $3.7{\pm}2.0$, p=0.002) Lauren의 분류에 따른 장형 위암에서 장형이 아닐 때보다 높은 SUVmax를 보였다($5.4{\pm}2.8$ vs. $3.7{\pm}1.3$, p=0.003). 원발 종양의 SUVmax는 p53 양성인 경우가 음성인 경우보다 의미 있게 높았다($6.0{\pm}2.8$ vs. $4.4{\pm}3.0$, p=0.035). 그 외 림프절 전이 유무, 종양 분화, Ki-67 지수, EGFR, Cathepsin D, c-erb-B2 그리고 COX-2 같은 다른 지표들은 원발성 위암의 SUVmax와 의미 있는 상관 관계가 없었다. 결론: 원발성 위암의 침범 깊이(T기)는 FDG PET/CT 스캔에서의 위암 발견율에 영향을 주었다. 위암이 PET/CT스캔에서 인지 가능한 FDG 섭취를 보일 경우 T기, 종양의 크기, Lauren의 분류에 따른 조직형, 그리고 p53의 발현 정도는 원발성 위암의 FDG 섭취와 유의한 상관 관계가 있었다.