• 제목/요약/키워드: p67

검색결과 5,721건 처리시간 0.036초

유기인제 농약 폭로로 인한 혈중 Cholinesterase 활성치와 요중 P-nitrophenol의 배설량의 변동 (Alterations of Blood Cholinesterase Activity and Urinary Para-nitrophenol Excretion After Exposure to Organophosphorus Insecticides)

  • 이병국;정규철
    • Journal of Preventive Medicine and Public Health
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    • 제7권1호
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    • pp.115-121
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    • 1974
  • In order to evaluate the health hazard due to exposure to organophosphorus insecticides, we measured the blood cholinesterase activity ana urinary para-nitrophenol among 56 exposed subjects. They are orchard workers, rice plant workers and smithion factory workers. The clinical symptoms were also checked by physicians. We also measured the blood cholinesterase activity and urinary para-nitrophenol excretion of 20 urban people and 15 rural people who had never been exposed to organophosphorus insecticides in order to compare them according to age, sex and geographical differences. And these results were also compared with those of exposed groups. The results obtained were as follows. 1. The normal plasma cholinesterase activity and cell cholinestrase activity were $0.861{\pm}0.148\;{\Delta}pH/hr$ and $0.822{\pm}0.154\;{\Delta}pH/hr$. And normal para-nitrophenol in urine was $1.21{\pm}0.52mg/liter$. 2. No significant difference was existed in blood cholinesterase activities and urinary para-nitrophenol excre tion according to sex, age and geographical difference. 3. The plasma cholinesterase activity and cell cholinesterase activity of orchard workers, rice plant workers and smithion factory workers were $0.682{\pm}0.189\;{\Delta}pH/hr,\;0.775{\pm}0.160\;{\Delta}pH/hr,\;0.754{\pm}0.123\;{\Delta}pH/hr,\;and\;0.691{\pm}0.082\;{\Delta}pH/hr,\;0.756{\pm}0.117\;{\Delta}pH/hr,\;0.739{\pm}0.117\;{\Delta}pH/hr$. And significant decreses in blood cholinesterase activities were existed among orchard workers and smithion factory workers compared with control group. 4, The urinary para-nitrophenol excretions of orchard workers, rice plant workers and smithion factory workers were $1.33{\pm}0.66mg/liter,\;1.19{\pm}0.88mg/liter\;and\;1.37{\pm}0.67mg/liter$ and there were no significant difference between exposed groups and control group. 5. The clinical symptoms complained during and after organophosphorus insecticides exposure were frequently ranked by headache (67.7%) and vertigo (64.5%) and muscular ataxia and weakness (51.6%).

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부수게 제조(製造)에 관한 연구 -제 1 보 : 수침공정(水浸工程)이 원료찹쌀의 점도(粘度)와 팽화력(膨化力)에 미치는 영향- (Studies on Manufacture of Busuge -I. Effect of Steeping Process on Viscosity and Raising Power of Glutinous Rice-)

  • 양희천;홍재식;김중만
    • 한국식품과학회지
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    • 제14권2호
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    • pp.141-145
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    • 1982
  • 부수게 제조공정중 원료찹쌀의 수침공정이 원료찹쌀의 산도, 점도, 금속이온 및 인의 함량에 미치는 영양과 이들 결과가 부수게 제품의 물성에 밀접한 관계가 있는 팽화율에 어떤 영향을 주는지를 알고저 하였다. 원료 찹쌀을 $10^{\circ}C$에서 20일 동안 수침한 결과 최초의 총산도는 0.03%에서 1.02%까지 증가하였고 점도는 수침 일수가 길어 짐에 따라 처음 점도 25.5cP가 점점 증가하여 14일에 최고점도 30.3cP를 나타냈고 그 후에는 23.5cP로 낮아졌다. 또한 찹쌀 중의 K, Na, P은 수침 초기에 Ca, Mg는 수침 중기에 많이 용출되었는데 20일간 K는 68%, Na는 67%, Ca는 85%, Mg는 81%, P는 16%가 용출되고 팽화력은 수침중 산도의 증가에 비례적으로 증가하여 최초 180이던 것이 수침 20일에는 251로 증가하였다. 수침에 의한 찹쌀의 점도 증가는 산도의 증가보다 양이온과 무기인(無機燐)의 용출에 크게 영향을 받으며 팽화력은 유기산의 존재와 양이온에 무기인의 용출로 증가되었으나 수침중 생성된 산에 의한 영향이 더욱 컸다.

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국내 및 국외 가정용 마아가린의 지방산(脂肪酸) 조성(組成)에 대한 연구(硏究) (Fatty Acid Composition of Domestic and Foreign Margarine for Home Use)

  • 최춘언;김혜위
    • 한국식품과학회지
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    • 제18권4호
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    • pp.301-305
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    • 1986
  • 국내(여름제품12종, 겨울제품12종) 및 국외(미국4종, 일본8종, 덴마크2종)외 가정용 마아가린의 지방산 조성(賠紡酸 組成)을 GLC에 의해 분석비교(分析比較)하여 보았다. 국내산 마아가린의 주요구성지방산(主要構成脂肪酸)은 palmitic acid(16 : 0). stearic acid(18 : 0). oleic acid(18 : 1). linoleic acid(18 : 2), linolenic acid(18 : 3)로 외국산과 같았으며, P/S비는 겨울제품이 $0.40{\sim}1.74$, 여름제품이 $0.21{\sim}1.82$로 겨울제품의 부포화도(不胞和度)가 여름제품보다 높은 경향(傾向)이었다. 한편, 외국산 마아가린의 P/S비는 $0.82{\sim}2.91$ 이었고, 이 중(中) stick 형(型)과 soft형(型)의 P/S비는 각각 $0.82{\sim}2.59,\;0.90{\sim}2.67$로 비슷하였다. 특히, P/S비가 높은 마아가린은 PUFA형(型) 마아가린이었으며, 그 값은 2.91이었다. 국내마아가린이 외국산 마아가린에 비하여 P/S비가 낮은 경향을 보이고 있으나. 외국산 마이가린의 P/S비에 상당하는 제품도 다수 있었다.

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부산지역 대학교 급식소의 급식서비스 만족도와 고객충성도와의 관계 (Relationship between Satisfaction with Foodservice and Customer Loyalty of University Students in Busan)

  • 이경아;류은순
    • 한국식품조리과학회지
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    • 제26권4호
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    • pp.413-421
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    • 2010
  • The purpose of this study was to improve the satisfaction of college foodservice customers by analyzing the correlation between college student satisfaction with foodservice and customer loyalty. The questionnaire was distributed to 480 customers at six universities in Busan. The average customer satisfaction score was 2.76, and customer satisfaction was highest with food, followed by sanitation, environment, and service (in decreasing order). Customers reported the frequency with which they were satisfied when using university foodservice operations (on an increasing scale from "almost never" to "more than five times") in four areas: food (p<0.001), service (p<0.01), sanitation (p<0.05), and environment (p<0.001). The average scores of customer loyalty, intent to purchase again, intent to advertise by word-of-mouth, and intent to switch were 2.67, 2.83, 2.52, and 2.67, respectively, and these scores demonstrated differences according to frequency of foodservice use (p<0.001). Food, service, sanitation, and environment correlated significantly (+) with customer loyalty. Intent to repeat purchase showed the highest correlation with food quality (p<0.05), and intent to advertise by word-of-mouth and to continue patronizing foodservice demonstrated the highest correlations with service (p<0.01). After classifying customers into four groups according to customer satisfaction and loyalty, a comparison was done to determine satisfaction and loyalty by each customer strata. In the "loyalist" group, satisfaction with environment and the intent to advertise by repurchase were significantly higher than in the other groups (p<0.001). In "defectors" group, satisfaction with service and the intent to advertise by word-of-mouth were significantly lower than in the other groups (p<0.001).

카자흐스탄 구리제련소 슬래그 내 구리회수를 위한 선별 특성 (Characteristic of Flotation for Recovery of Copper from Copper Slag in Kazakhstan)

  • 박제현;최의규;최홍일;신승한
    • 자원리싸이클링
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    • 제24권4호
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    • pp.12-21
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    • 2015
  • 일반적으로 구리제련 슬래그내 구리함량은 0.5-3.7% 혹은 그 이상의 높은 비율로 포함되어 있며, 슬래그내 구리회수에 대한 대표적인 방법으로는 부유선별, 침출 그리고 배소가 있다. 본 연구에서는 부유선별법에 의한 구리 회수방법을 검토하였으며, 잔세이트포수제를 이용한 황화부선을 수행하였다. 산성과 알칼리 조건에서 부유선별 특성을 관찰하였으며, pH 4 에서 구리회수율 50%, pH 11 에서 구리회수율 67%로 나타났으며, 특히 pH 11에서는 $100{\mu}m$ 이상의 입자가 정광으로 부유되어 회수율이 상대적으로 높게 나타나는 경향을 보였다. 슬래그 입도를 200 mesh 이하로 분쇄하여 단체분리도를 향상시켜 pH조건별 부유선별 실험을 수행한 결과, 회수율이 78 - 83%까지 향상되는 것을 확인할 수 있었다.

Scutellaria baicalensis Inhibits Coxsackievirus B3-Induced Myocarditis Via AKT and p38 Pathways

  • Fu, Qiang;Gao, Lu;Fu, Xiao;Meng, Qinghua;Lu, Zhihong
    • Journal of Microbiology and Biotechnology
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    • 제29권8호
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    • pp.1230-1239
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    • 2019
  • Scutellaria baicalensis Georgi has been widely used in China for treatment of various diseases. This study investigated the effect of Scutellaria baicalensis Georgi extracts (SBE) against Coxsackievirus B3 (CVB3)-induced myocarditis in vitro and in vivo. In vitro, Hela cells and primary myocardial cells were infected with CVB3 and treated with SBE ($50-800{\mu}g/ml$) and ribavirin ($200{\mu}M$) for 48 h and then determined by CCK8 assay. Real-time PCR and western blotting assays were performed. In vivo, a myocarditis model was induced in male BALB/c mice by injecting CVB3 suspension intraperitoneally for three times, followed by treatment with SBE (400 and 200 mg/kg) and ribavirin (100 mg/kg) for 28 days. SBE ameliorated the cytotoxicity of CVB3 in Hela cells, especially at $400{\mu}g/ml$ (39.93% vs 65.67%, p < 0.05) without influencing cell growth and also significantly reduced CVB3 replication in primary myocardial cells. The levels of AKT, ERK, and p38 were increased after CVB3 infection. SBE could downregulate the expressions of AKT and p38. In vivo, the mortality rate from CVB3 reached to 66.67%, while 10.00% and 23.33% of this came after 400 and 200 mg/kg SBE treatment, respectively (p < 0.05). The CVB3 replication was obviously reduced after SBE administration from day 5. Similarly, the levels of AKT, ERK, and p38 mRNAs and proteins were increased, and SBE suppressed the expression of AKT and p38. Our study indicates that SBE is a promising potent antiviral agent against CVB3-induced myocarditis by inhibition of virus replication via depressing AKT and p38 expressions.

원발성 다형선종과 재발성 다형선종의 면역조직화학적 특성 (Immunohistochemical Characteristics of Primary and Recurrent Pleomorphic Adenoma)

  • 서명환;하정훈;이경분;정영호;권성근;김광현;성명훈
    • 대한두경부종양학회지
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    • 제21권2호
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    • pp.146-150
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    • 2005
  • Background and Objectives: When the pleomorphic adenoma(PA) recures, the tumor tends to become a multinodular mass that infiltrates into the normal tissue which is not a common condition for a benign tumor. This manifestation is probably due to the difference in cell biology of the recurrent tumor compared to that of the primary PA. The aim of this study is to assay the immunhistochemical characteristics of the recurrent PA compared to the primary PA and to evaluate whether this property can be used for developing a method that can select the patients who have higher risk to recur. Materials and Methods: Thirteen patients were enrolled in the primary PA group and 15 patients who had a recurrent PA were enrolled in the recurrent PA group. To evaluate the cell biology of the tumor, immunohistochemical stainings of Ki-67, bcl-2 and p53 were performed. Results: There was no difference in the expression of Ki-67 (p=0.117, p=.208) and p53 (p=.430, p=.328). The extent stained by bcl-2 was significantly larger in the recurrent PA group (p=.033, p=.014). The expression of bcl-2 did not increase while time passed. Conclusion: The high expression of bcl-2 seems to be a property of the recurrent PA group which can be found even during first operation before recurrence. By this immunhistochemical characteristic, we would be able to sort out the patients who have higher risk to recur.

Impact of Collateral Circulation on Futile Endovascular Thrombectomy in Acute Anterior Circulation Ischemic Stroke

  • Yoo Sung Jeon;Hyun Jeong Kim;Hong Gee Roh;Taek-Jun Lee;Jeong Jin Park;Sang Bong Lee;Hyung Jin Lee;Jin Tae Kwak;Ji Sung Lee;Hee Jong Ki
    • Journal of Korean Neurosurgical Society
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    • 제67권1호
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    • pp.31-41
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    • 2024
  • Objective : Collateral circulation is associated with the differential treatment effect of endovascular thrombectomy (EVT) in acute ischemic stroke. We aimed to verify the ability of the collateral map to predict futile EVT in patients with acute anterior circulation ischemic stroke. Methods : This secondary analysis of a prospective observational study included data from participants underwent EVT for acute ischemic stroke due to occlusion of the internal carotid artery and/or the middle cerebral artery within 8 hours of symptom onset. Multiple logistic regression analyses were conducted to identify independent predictors of futile recanalization (modified Rankin scale score at 90 days of 4-6 despite of successful reperfusion). Results : In a total of 214 participants, older age (odds ratio [OR], 2.40; 95% confidence interval [CI], 1.56 to 3.67; p<0.001), higher baseline National Institutes of Health Stroke Scale (NIHSS) scores (OR, 1.12; 95% CI, 1.04 to 1.21; p=0.004), very poor collateral perfusion grade (OR, 35.09; 95% CI, 3.50 to 351.33; p=0.002), longer door-to-puncture time (OR, 1.08; 95% CI, 1.02 to 1.14; p=0.009), and failed reperfusion (OR, 3.73; 95% CI, 1.30 to 10.76; p=0.015) were associated with unfavorable functional outcomes. In 184 participants who achieved successful reperfusion, older age (OR, 2.30; 95% CI, 1.44 to 3.67; p<0.001), higher baseline NIHSS scores (OR, 1.12; 95% CI, 1.03 to 1.22; p=0.006), very poor collateral perfusion grade (OR, 4.96; 95% CI, 1.42 to 17.37; p=0.012), and longer door-to-reperfusion time (OR, 1.09; 95% CI, 1.03 to 1.15; p=0.003) were associated with unfavorable functional outcomes. Conclusion : The assessment of collateral perfusion status using the collateral map can predict futile EVT, which may help select ineligible patients for EVT, thereby potentially reducing the rate of futile EVT.

전기분해에 의한 염색폐수 처리공정에 관한 연구 (A study on dye wastewater treatment using the electrolysis)

  • 김성국;박상원;홍대일
    • 한국환경과학회지
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    • 제8권4호
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    • pp.539-545
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    • 1999
  • Dye wastewater was treated by using an electrochemical oxidation process. Various combinations of electrodes such as carbon, Al and Fe were investigated. In this study, electrode material, electrolyte concentration, electrode distance, current density, and pH value were found to have significant effect on both pollutant removal efficiency and current efficiency in electrochemical oxidation process. After electrolysis for 40min with carbon/Al, it was observed that COD, $T-N, NH_{4}^{+}-N$ and color of treated wastwater were reduced from 580mg/$\ell$ to 145mg/$\ell$, 67.2mg/$\ell$ to 26.8mg/$\ell$, 46.8mg/$\ell$ to 1.4mg/$\ell$, and 4200 Pt-Co units to 336 Pt-Co units, respectively. The optimal conditions of the electrooxidation process to treat the wastewater for this study were found to be such : current density ; 16.67mA/$cm^2$, electrode distance ; 2.5cm, pH value ; 5.0 and carbon/Al electrode.

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