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Explosion Hazards and Flame Velocity in Aluminum Powders (알루미늄 분체의 폭발위험성과 화염전파속도)

  • Han, Ou-Sup;Lee, Su-Hee
    • Journal of the Korean Institute of Gas
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    • v.16 no.5
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    • pp.7-13
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    • 2012
  • An experimental study has been done to investigate the explosion characteristics of aluminum powders with different sizes and concentrations in a 20 L spherical explosion vessel. Two different sizes of aluminum powder were used : $15.1{\mu}m$ and $34.8{\mu}m$ with a volume mean diameter. The results revealed that $15.1{\mu}m$ Al powder has a Lower explosion limit (LEL) of $40g/m^3$, a maximun explosion pressure ($P_{max}$) of 9.8 bar and a maximum rate of pressure rise ($[dP/dt]_{max}$) of 1852 bar/s, in $34.8{\mu}m$ Al powder, LEL of $70g/m^3$, $P_{max}$ of 7.9 bar and $[dP/dt]_{max}$ of 322 bar/s. The LEL of Al powders tended to increase with the increase of particle size. Also, it was found that the flame velocity calculated from the powder with $15.1{\mu}m$ was about 5 times higher than that of the powder of $34.8{\mu}m$.

Relationships of Job Stress, Fatigue & Depression among one Ship-building Supply Workers (일 조선업 협력업체 근로자의 직무 스트레스, 피로 및 우울과의 관계)

  • Kim, Sang-Dol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.5
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    • pp.2789-2796
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    • 2014
  • This is a descriptive correlation study to identify job stress, fatigue, and depression among ship-building supply workers. The subjects were 175 ship-building supply workers at one small & medium-sized ship-building supply company in K city. The data were collected from February 1st throughout 28th, 2013. The collected data were analyzed using the SAS program through mean, standard deviation, and Pearson's correlation coefficients. There was a positive correlation between job need and job insecurity of the job stress underlying factors and fatigue respectively (r=0.15, p<.05; r=0.17, p<.05). There was a negative correlation between organizational system factor and fatigue (r=-0.19, p<.05). Also there was a positive correlation between workplace culture factor and depression (r=0.15, p<.05). In conclusion, it could be needed for organizational managers to develop strategies for improving the workers' psychosocial workplace environment.

A Novel SLC25A15 Mmutation Causing Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome (Hyperornithinemia-hyperammonemia-homocitrullinuria 증후군을 유발하는 SLC25A15 유전자의 새로운 변이)

  • Jang, Kyung Mi;Hyun, Myung Chul;Hwang, Su-Kyeong
    • Journal of the Korean Child Neurology Society
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    • v.25 no.3
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    • pp.204-207
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    • 2017
  • Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome (HHH syndrome) is a neurometabolic disorder with highly variable clinical severity ranging from mild learning disability to severe encephalopathy. Diagnosis of HHH syndrome can easily be delayed or misdiagnosed due to insidious symptoms and incomplete biochemical findings, in that case, genetic testing should be considered to confirm the diagnosis. HHH syndrome is caused by biallelic mutations of SLC25A15, which is involved in the urea cycle and the ornithine transport into mitochondria. Here we report a boy with spastic paraplegia and asymptomatic younger sister who have compound heterozygous mutations of c.535C>T (p.R179*) and c.116C>A (p.T39K) in the SLC25A15 gene. We identified that p.T39K mutation is a novel pathogenic mutation causing HHH syndrome and that p.R179*, which is prevalent in Japanese and Middle Eastern heritage, is also found in the Korean population.

Capacitation and acrosome reaction differences of bovine, mouse and porcine spermatozoa in responsiveness to estrogenic compounds

  • Ryu, Do-Yeal;Kim, Ye-Ji;Lee, June-Sub;Rahman, Md. Saidur;Kwon, Woo-Sung;Yoon, Sung-Jae;Pang, Myung-Geol
    • Journal of Animal Science and Technology
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    • v.56 no.7
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    • pp.26.1-26.10
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    • 2014
  • Background: Endocrine disruptors are exogenous substance, interfere with the endocrine system, and disrupt hormonal functions. However, the effect of endocrine disruptors in different species has not yet been elucidated. Therefore, we investigated the possible effects of $17{\beta}$-estradiol (E2), progesterone (P4), genistein (GEN) and 4-tert-octylphenol (OP), on capacitation and the acrosome reaction in bovine, mouse, and porcine spermatozoa. In this in vitro trial, spermatozoa were incubated with $0.001-100{\mu}M$ of each chemical either 15 or 30 min and then assessed capacitation status using chlortetracycline staining. Results: E2 significantly increased capacitation and the acrosome reaction after 30 min, while the acrosome reaction after 15 min incubation in mouse spermatozoa. Simultaneously, capacitation and the acrosome reaction were induced after 15 and 30 min incubation in porcine spermatozoa, respectively. Capacitation was increased in porcine spermatozoa after 15 min incubation at the lowest concentration, while the acrosome reaction was increased in mouse spermatozoa after 30 min (P < 0.05). E2 significantly increased the acrosome reaction in porcine spermatozoa, but only at the highest concentration examined (P < 0.05). P4 significantly increased the acrosome reaction in bovine and mouse spermatozoa treated for 15 min (P < 0.05). The same treatment significantly increased capacitation in porcine spermatozoa (P < 0.05). P4 significantly increased capacitation in mouse spermatozoa treated for 30 min (P < 0.05). GEN significantly increased the acrosome reaction in porcine spermatozoa treated for 15 and 30 min and in mouse spermatozoa treated for 30 min (P < 0.05). OP significantly increased the acrosome reaction in mouse spermatozoa after 15 min (P < 0.05). Besides, when spermatozoa were incubated for 30 min, capacitation and the acrosome reaction were higher than 15 min incubation in E2 or GEN. Furthermore, the responsiveness of bovine, mouse and porcine spermatozoa to each chemical differed. Conclusions: In conclusion, all chemicals studied effectively increased capacitation and the acrosome reaction in bovine, mouse, and porcine spermatozoa. Also we found that both E2 and P4 were more potent than environmental estrogens in altering sperm function. Porcine and mouse spermatozoa were more responsive than bovine spermatozoa.

Clinical Study and Risk Factors of Surgical Mortality of Congenital Heart Defects (선천성 심장기형의 임상고찰 및 수술사망율에 미치는 위험인자의 분석)

  • 이상호;김병균
    • Journal of Chest Surgery
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    • v.30 no.1
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    • pp.17-26
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    • 1997
  • Objeitives. The surgical mortality of congenital heart defects has been reduced (or the very young age group. Especially, young age at repair is an important risk factor for mortality after repair of tetralogy of Falloff. Some risk factors were analyzed Methods. Three hundred and sixty six patients underwent surgical Intervention. Ages ranged from 5 days to 64 years, and 80 patients were adults(over 15 years of age). The defects consisted of 313(84.2%) acyanotic and 53(15.8%) cyanotic anomalies. The surgical mortalities were evaluated by univariate and multivariate analysis. Results. The overall surgical mortality was 10.4%. Mos deaths occurred in the infant group younger than 6 months(20/38 deaths) and in cyanotic group(21/38 deaths). Surgical infant mortality younger than 12 months was 24.8%(25/101). Risk factors of mortality in open heart surgery were age(p< 0.0001), body weight(p< 0.0001), pump time(p< 0.0001), aortic cross clamp time(p< 0.0001), use of total circulatory arrest(p<0.0001) and cyanotic disease(p<0.0001) by univariate analysis. But by multivariate analysis, the risk factor of mortality in open heart surgery was disease entity(p=0.002) only. A disease group with the highest risk was a cyanotic group(odds ratio was 15.3 relative to ventricular septal defect) excluding tetralogy of Falloff(odds ratio=0.27). Conclusions. Even though the most important risk factor was disease entity, we should conentrate our efforts on the technically improvable factors affecting surgical mortality indicated by univarlate analysis.

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Effect of Eu in Partial Oxidation of Methane to Hydrogen over Ln(1)-Ni(5)/SBA-15 (Ln = Dy, Eu, Pr, and Tb) Catalysts (Ln(1)-Ni(5)/SBA-15 (Ln = Dy, Eu, Pr, Tb) 촉매상에서 수소제조를 위한 메탄의 부분 산화 반응에서 Eu의 효과)

  • Seo, Ho Joon
    • Applied Chemistry for Engineering
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    • v.32 no.4
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    • pp.478-482
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    • 2021
  • The catalytic yields of partial oxidation of methane (POM) to hydrogen over Ln(1)-Ni(5)/SBA-15 (Ln = Dy, Eu, Pr, and Tb) were investigated in a fixed bed flow reactor under atmosphere. As 1 wt% of Eu was added to Ni(5)/SBA-15 catalyst, the O1s and Si2p core electron levels of Eu(1)-Ni(5)/SBA-15 showed the chemical shift by XPS. XPS analysis also demonstrated that the atomic ratio of O1s, Ni2p3/2, and Si2p increased to 1.284, 1.298, and 1.058, respectively, and exhibited O-, and O2- oxygen and metal ions such as Eu3+, Ni0, Ni2+, and Si4+ on the catalyst surface. The yield of hydrogen on the Eu(1)-Ni(5)/SBA-15 was 57.2%, which was better than that of Ln(1)-Ni(5)/SBA-15 (Ln = Dy, Pr, and Tb), the catalytic activity was kept steady even 25 h. As 1 wt% of Eu was added to Ni(5)/SBA-15, the oxygen vacancies caused by strong metal-support interaction (SMSI) effect due to the strong interaction between metals and carrier are made. They are resulted in increasing the dispersion of Ni0, and Ni2+ nano particles on the surface of catalyst, and are kept catalytic activity.

15-Deoxy-${\Delta}^{12,14}$-Prostaglandin $J_2$ Upregulates the Expression of LPS-Induced IL-8/CXCL8 mRNA in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats

  • Kim, Jung-Hae;Kim, Hee-Sun
    • IMMUNE NETWORK
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    • v.9 no.2
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    • pp.64-73
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    • 2009
  • Background: 15d-$PGJ_2$ has been known to act as an anti-inflammatory agent and has anti-hypertensive effects. As a result of these properties, we examined the effect of 15d-$PGJ_2$ on the LPS-induced IL-8/CXCL8 mRNA expression in VSMCs from SHR. Methods: Effect and action mechanism of 15d-$PGJ_2$ on the expression of LPS-induced IL-8/CXCL8 mRNA in VSMCs from SHR and WKY were examined by using real-time polymerase chain reaction, electrophoretic mobility shift assay for NF-${\kappa}B$ avtivity, Western blotting analysis for ERK and p38 phosphorylation and flow cytometry for NAD(P)H oxidase activity. Results: 15d-$PGJ_2$ decreased the expression of LPS-induced IL-8/CXCL8 mRNA in WKY VSMCs, but increased the expression of LPS-induced IL-8/CXCL8 mRNA in SHR VSMCs. The upregulatory effect of 15d-$PGJ_2$ in SHR VSMCs was mediated through PPAR${\gamma}$, and dependent on NF-${\kappa}B$ activation and ERK phosphorylation. However, inhibition of the p38 signaling pathway augmented the upregulatory effect of 15d-$PGJ_2$ on LPS-induced IL-8/CXCL8 mRNA. A NAD(P)H oxidase inhibitor inhibited the upregulatory effect of 15d-$PGJ_2$ on LPS-induced IL-8/CXCL8 mRNA expression in SHR VSMCs, and an increase in NAD(P)H oxidase activity was detected in SHR VSMCs treated with 15d-$PGJ_2$/LPS. Conclusion: Our results indicate that the upregulatory effect of 15d-$PGJ_2$ on LPS-induced IL-8/CXCL8 expression in SHR VSMCs is mediated through the PPAR${\gamma}$ and ERK pathway, and may be related to NAD(P)H oxidase activity. However, p38 inactivation may also play an important role in 15d-$PGJ_2$/LPS-induced IL-8/CXCL8 expression in SHR VSMCs.

Effects of pH of Washing Solution, Washing Frequency and Individual Bull on Proton Concentration in the Sperm Washed Solution and Sperm Acrosome Reaction (精子 洗滌液의 pH와 洗滌頻度 및 수소個體가 精子洗滌液內 水素이온濃度와 소 精子의 尖帽反應에 미치는 影響)

  • Park, Yeong-Sik;Im, Gyeong-Sun
    • Korean Journal of Animal Reproduction
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    • v.15 no.1
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    • pp.7-13
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    • 1991
  • This study was carried out to investigate the effects of pH of sperm-washing solution, sperm-washing frequency and individual bull on concentration of hydrogen ion in sperm-washed solution and sperm acrosome reaction. The results obtained were as follow. 1. When bovine sperm was washed at 4 times with SHP solution and incubated, the difference of light absorbance between sperm-washing and sperm-washed solution(${\Delta}$Ao-${\Delta}$At) was higher in 2nd sperm-washed solution than that in the other washed solutions. 2. When sperm was thrice washed with SHP solutions of pH 5.99, 6.38, 6.78, 7.10, 7.40, 7.69, 8.15, 8.45, and 8.83, ${\Delta}$Ao-${\Delta}$At was significantly increased at pH7.69 to 8.83, and ${\Delta}$Ao-${\Delta}$At in 1st sperm washed solution was significantly higher than that in 2nd and 3rd sperm washed solution. 3. When sperm of Holstein, KNC and Hereford was thrice washed with SHP solutions of pH 5.99, 6.38, 6.78, 7.10, 7.40, 7.69, 8.15, 8.45, and 8.83, Holstein showed higher ${\Delta}$Ao-${\Delta}$At of sperm Washed solution than KNC and Hereford, and ${\Delta}$Ao-${\Delta}$At in sperm washed solution was significantly increased at 7.69 for Holstein and at 8.15 for KNC and Hereford, respectively. 4. When sperm was thrice with SHP solution of pH 6.8, 7.1 and 7.4, and then incubated in mTALP of pH 7.4 for 15 minutes, in 1st and 2nd sperm washing ${\Delta}$Ao-${\Delta}$At of sperm washed solution was significantly higher at pH 7.1 and 7.4 than at pH 6.8, and the sperm acrosome reaction of pH 6.8, 7.1 and 7.4 was 49.1, 68.8 and 72.9%, respectively. The sperm acrosome reaction of pH 7.1 and 7.4 was higher than that of pH 6.8.

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Factors Affecting the Retention Intention of the Emergency Room Nurse to Promote Life Care (응급실 간호사의 라이프케어 증진을 위한 재직의도에 영향을 미치는 요인)

  • Jung, Ji-Hyeon;Park, Huyn-Jung
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.4
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    • pp.287-297
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    • 2021
  • This study was to investigate the relationship of job stress, health status, and health promotion behavior, retention intention and to identify the influencing factors on retention intention of nurse in Emergency Room(ER). The subjects were 155 ER nurses working at 15 general hospital in Gwangju, Korea. The data were collected from October 15, 2020 to November 3, 2020. The result, there were negative correlation between job stress and health promotion behavior(r=-0.310, p=<.000), between job stress and retention intention(r=-0.220, p=.006), between health status, and health promotion behavior(r=-0.448, p=<.000), between health status and retention intention(r=-0.296, p=<.000), but there were positive correlation between job stress and health status(r=0.368, p=<.000), between health promotion behavior and retention intention(r=0.229, p=.004). Factors influencing retention intention were fatige and health status with R2 value 22.7%. Considering these results, it seems that important factors determining the retention intention of nurses in ER are Spiritual health status, heavy workload due to job stress, fatigue and social health status by nurse. Therefore, in order to increase the retention intention of nurse in ER, it is a need for strategies to improve the working environment and develop programs to reduce job stress and fatigue through work adjustment, and to maintain and promote health.