• 제목/요약/키워드: p-TS

검색결과 395건 처리시간 0.025초

Effects of polysaccharide fractions from phellodendron chinese SCHNEID on tumor progression and immunopontentiation

  • Jun, Kya-I;Lee, Tae-Kyun;Kim, Cheorl-Ho
    • Advances in Traditional Medicine
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    • 제1권1호
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    • pp.37-44
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    • 2000
  • In the previous paper (Kim et al., Glycoconjugate Journal 16, 247-252, 1999), heteropolysaccharides from Korean medicinal plant, Phellodendri cortex (Hwangbek) showed a poten B-Iymphocyte-stimulating activity in a system using polyclonal antibody forming cells in C57BL/6XC3H mice at dosages of 2-10 mg. In a series of biolgical active polysaccharides from natural medicinal plants, the polysaccharide fractions were isolated and purified from Phellodendron chinese SCHNEID, and antitumor activities were examined at dosages of 2, 5 and 10 mg/100 g. F-7 and F-8 showed the highest tumor inhibitory activities (inhibition ratio 96.4 and 98.2% in 2 mg/100 g), and in dose of 5 mg/100 g, the inhibitory ratios were 95.3 and 97.5%, respectively. Furthermore, 10 mg/100 g of intraperitoneal (i.p.) injection gave 97.3 and 98.7% of inhibition. In oral administration, the inhibitory activities were not markedly observed, indicating that the polysaccharides are directly acting to immune system. When the effects on TS and TK activities were determined, TS activities in the F-2 and F-7-treated mice were markedly suppressed to 73.7% and 79.5% of that in the control (p<0.01), while there was little difference in TK activity with a slight decrease in F-2 only. However, in i.p. injection, TS activities in the F-2, F-5, F-7 and F-8-treated mice were markedly suppressed to 83% to 85% of that in the control (p<0.01). Furthermore, there was also significant differences in TK activities in F-2, F-5, F-7 and F-8-treated mice (p<0.05). Therefore, polysaccharide fraction F-8 was further purified to active fractions of F-9 and F-11 by gel permeation chromatography using TSK Gel HW50S. The purified polysaccharides of F-9 and F-11 were composed of GlcNAc (47.3%), Gal (24.7%) and Man (28.0%). These results clearly indicated that the i.p. injection is much effective to suppress tumor growth than oral administration.

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Ecosystem Health Diagnosis Using Integrative Multiple Eco-metric Model Approaches

  • Kim, Hyun-Mac;Choi, Ji-Woong;An, Kwang-Guk
    • Journal of Ecology and Environment
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    • 제36권1호
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    • pp.73-83
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    • 2013
  • The object of this study was to evaluate lotic ecosystem health using multiple eco-metric approaches such as water chemistry diagnosis, physical habitat health evaluations, and biological integrity modeling at 100 streams of four major watersheds. For the study, eight chemical water quality parameters such as nutrients (N, P) and organic material were measured and 11-metric models of Qualitative Habitat Evaluation Index (QHEI) and multiple eco-metric health assessment model (MEHA) were applied to the four major watershed. Nutrient analysis of nitrogen (N) and phosphorus (P) in all watersheds indicated a eutrophic state depending on the locations of sampling streams. Physical habitat health, based on the QHEI model, averaged 114 (range: 56 - 194), judging as a "good condition" by the criteria of Plafkin et al. (1989). In addition, primary (H1 - H4), secondary (H5 - H7), and tertiary habitat metric variables (H8 - H11) were analyzed in relation to the physical habitat degradations. The plots of tolerant species ($P_{TS}$) and sensitive species ($P_{SS}$) to water quality showed that the proportions of $P_{TS}$ had positive linear functions with nutrients, and that the $P_{SS}$ had inverse linear relations with the chemical variables. The model of eco-metric health assessment showed that mean MEHA was 20.4, indicating a fair condition. Overall, our data suggest that water chemistry, based on nutrients and organic matter, directly modified the trophic structures in relation to food chain in the aquatic ecosystems, and then these directly influenced the compositions of tolerance/sensitive species, resulting in degradations of overall ecological health.

연속반응공정을 이용한 유기성자원으로부터 수소생산을 위한 최적인자도출에 관한 연구 (Deduction of Optimum Factors for Hydrogen Production from Organic Resources using a Continuous Reaction Process)

  • 김충곤;신현곤
    • 유기물자원화
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    • 제19권2호
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    • pp.22-27
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    • 2011
  • 본 연구에서는 음식물류폐기물폐수와 양돈폐수를 특별히 전처리 하지 않고 3:7의 비율로 혼합하여 연속반응공정을 이용한 수소생산의 최적 인자를 도출하기 위해 연구를 수행하였다. 본 연구결과 수소발생량은 pH 5.5의 조건에서 가장 많이 발생하였으며, 이를 통해 음식물류폐기물과 양돈폐수의 혼합시의 수소생산의 최적 pH는 5.5 임을 확인하였다. HRT에 따른 수소발생량은 3일보다 4일의 경우에 높은 수소발생량을 보였으며, 이는 HRT값의 변화에 따라 수소발생미생물의 활성에 크게 관여하는 것으로 HRT역시 수소발생미생물에 중요한 인자로 작용한다고 판단된다. 유기물의 제거율은 운전 6일째에 최대 TS 52%, VS 71%, TSS 83%, VSS 89%의 제거율을 기록하였으며, 수소생산 공정을 통하여도 유기물의 제거가 가능함을 확인하였다.

한국 물리치료사 국가 면허시험 합격 여부의 예측요인 탐색 (Exploring the Predictive Factors of Passing the Korean Physical Therapist Licensing Examination)

  • 김소현;조성현
    • 대한통합의학회지
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    • 제10권3호
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    • pp.107-117
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    • 2022
  • Purpose : The purpose of this study was to establish a model of the predictive factors for success or failure of examinees undertaking the Korean physical therapist licensing examination (KPTLE). Additionally, we assessed the pass/fail cut-off point. Methods : We analyzed the results of 10,881 examinees who undertook the KPTLE, using data provided by the Korea Health Personnel Licensing Examination Institute. The target variable was the test result (pass or fail), and the input variables were: sex, age, test subject, and total score. Frequency analysis, chi-square test, descriptive statistics, independent t-test, correlation analysis, binary logistic regression, and receiver operating characteristic (ROC) curve analyses were performed on the data. Results : Sex and age were not significant predictors of attaining a pass (p>.05). The test subjects with the highest probability of passing were, in order, medical regulation (MR) (Odds ratio (OR)=2.91, p<.001), foundations of physical therapy (FPT) (OR=2.86, p<.001), diagnosis and evaluation for physical therapy (DEPT) (OR=2.74, p<.001), physical therapy intervention (PTI) (OR=2.66, p<.001), and practical examination (PE) (OR=1.24, p<.001). The cut-off points for each subject were: FPT, 32.50; DEPT, 29.50; PTI, 44.50; MR, 14.50; and PE, 50.50. The total score (TS) was 164.50. The sensitivity, specificity, and the classification accuracy of the prediction model was 99 %, 98 %, and 99 %, respectively, indicating high accuracy. Area under the curve (AUC) values for each subject were: FPT, .958; DEPT, .968; PTI, .984; MR, .885; PE, .962; and TS, .998, indicating a high degree of fit. Conclusion : In our study, the predictive factors for passing KPTLE were identified, and the optimal cut-off point was calculated for each subject. Logistic regression was adequate to explain the predictive model. These results will provide universities and examinees with useful information for predicting their success or failure in the KPTLE.

Differences in Design Considerations between InGaN and Conventional High-Brightness Light-Emitting Diodes

  • Lee, Song-Jae
    • Journal of the Optical Society of Korea
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    • 제2권1호
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    • pp.13-21
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    • 1998
  • Based on the escape cone concepts, high-brightness light-emitting diodes (LEDs) have been analyzed. In AlGaAs or InGaAlP LEDs, photon absorption in the ohmic region under the electrode is known to be significant. Thus, ins general, a thick window layer (WL) and a transparent substrate (TS) would minimize photon shielding by the electrodes and considerably improve photon output coupling efficiency. However, the schemes do not seem to be necessary in InGaN system. Photon absorption in ohmic contact to a wide bandgap semiconductor such as GaN may be negligible and, as a result, the significant photon shielding by the electrodes will not degrade the photon output coupling efficiency so much. The photon output coupling efficiency estimated in InGaN LEDs is about 2.5 - 2.8 times that of the conventional high-brightness LED structures based on both WL and TS schemes. As a result, the extenal quantum efficiency in InGaN LEDs is as high as 9% despite the presumably very low internal quantum efficiency.

$Cul-Cu_2S-Cu_2O-MoO_3$계 유리의 전기전도 및 유전환화와의 상관 (Correlation between Electrical Conduction and Dielectric Relaxation in the Glass System $Cul-Cu_2S-Cu_2O-MoO_3$)

  • 이재형;임기조
    • 대한전기학회논문지
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    • 제43권7호
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    • pp.1152-1157
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    • 1994
  • The glasses were prpared in the system CuI-CuS12TS-CuS12TO-MoOS13T by rapid quenching technique. These glasses have high ionic conductivities at 2$0^{\circ}C$ in the range of 10S0-1T[S/m], and the conductivities increase with increasing CuI and CuS12TS content. The value of activation energy for dielectric relaxation is nearly identical with that for conductivity. The cole-Cole parameter $\beta$ for representation of the distribution of dielectric relaxation times varies the range from 0.92 to 0.96. This parameter has a weak dependence on the composition of glass, and is independent of temperature. The correlation factors P for the glasses shows from 1.1 to 1.7.

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Characterization of Cinnamaldehyde-Supplemented Soy Protein Isolate Films

  • Kim, Ki-Myong;Hanna, Milford A.;Weller, Curtis L.;Cho, Sung-Hwan;Choi, Sung-Gil
    • Food Science and Biotechnology
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    • 제15권4호
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    • pp.631-634
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    • 2006
  • Soy protein isolate (SPI) films were supplemented with cinnamaldehyde (CA) at concentrations of 0.1-0.5 mL/5 g SPI. The effects of CA on film color, tensile strength (TS), percent elongation at break (E, %) and water vapor permeability (WVP) of SPI films were investigated. Generally, total color difference (${\Delta}E$), WVP, and TS of SPI films increased gradually, while E and TSM decreased significantly (p<0.05) as the amount of cinnamaldehyde in the SPI films increased. Cinnamaldehyde can be used as a potential cross-linking agent for preparing SPI films by improving mechanical strength and water resistant properties.

폴리피롤을 고체전해질로 이용한 알루미늄 고체전해 캐패시터 (Aluminum Solid Electrolytic Capacitor Employing Polypyrrole as Solid Electrolyte)

  • 조준상;유남산;이상빈;박영서
    • 공업화학
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    • 제8권5호
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    • pp.784-789
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    • 1997
  • 전도성 고분자인 폴리피롤(PPy)을 전해질로 하는 알루미늄(Al)고체전해 캐패시터를 제작하기 위하여 알루미늄 산화피막($Al_2O_3$) 위에 화학산화중합(CP)법으로 얇은 PPy층을 형성시키고, 이 층을 양극으로 이용하여 피롤(Py)을 전해산화중합(EP)시켰다. 캐패시터 특성에 영향을 미치는 중합조건을 조사한 결과, 지지전해질로서 sodium p-toluenesulfonate (TsONa)를 사용하고, 소자당 2.0~4.0 mA의 정전류를 인가, 전해중합 후 제작한 캐패시터의 전기적 특성 및 임피던스 특성이 가장 우수하였다.

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손의 한랭자극이 인체생리반응과 의복의 쾌적성에 미치는 영향 -한랭혈관반응, 온랭감각, 한랭통증을 중심으로- (Effect of Cooling Hands in the Cold Water for the Physiological Responses and Clothing Comfort -Focused on Vascular Hunting Reaction, Thermal Sensation and Pain Sensation-)

  • 이원자
    • 복식문화연구
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    • 제12권2호
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    • pp.279-289
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    • 2004
  • This study was conducted to compare the hunting reaction of finger in the cold water. Finger skin temperature is measured the left middle finger tip immersion in cold water of 5℃ for 30 minutes and measurements were made on finger skin temperature(Ts), thermal comfort, and cold pain sensations during the experiment at the spring (March) and Winter(December). Results were follows. Is before immersion was at the highest in spring and at the lowest in winter and was closely related to the indoor temperature Ts during immersion and recovery. Mean of finger skin temperature(MST), the skin temperature at the first rise(TTR) and amplitude of finger skin temperature reaction during immersion(AT) were significant higher in spring than that in winter(P<.01). The lowest skin temperature(LST) during the cold water immersion were significantly higher in spring than that in winter (P<.05). The frequency of the appearance of cold-Induced vase dilation(CIVD) was higher in spring than that in winter. However, time for the first temperature(TTR) and recovery time(RT) had no seasonal variation. In addition, cold pains during immersion were felt more strongly in spring than in winter. Local thermal sensation, finger thermal sensation in dynamic state during hand immersion was different from that in the Winter. Spring was slowly cold in cold water immersion.

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EPC Sensor Network-based Product and Process Traceability System in the Food Supply Chain

  • Chun, Jung-Woo;Oh, Ji-Sung;Rho, Jae-Jueng;Lee, Jung-Wook
    • 한국경영정보학회:학술대회논문집
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    • 한국경영정보학회 2007년도 International Conference
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    • pp.184-189
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    • 2007
  • Concerns about food safety continue to rise and under this situation, governments of some countries have reinforced their regulations more strictly for food safety. In order to prevent food safety incidents or, at least to minimize the impact, the preparedness is very important. As a consequence of this, traceability system has become an essential tool for food safety. Recently, it requires more prevention-based food safety control system. One of the most generally used systems for food safety control is Hazard Analysis and Critical Control Point (HACCP). Both traceability and HACCP systems can be integrated through Electronic Product Code (EPC) Sensor Network technologies which have four value propositions. In this paper, we will introduce the concept of product and process traceability system (P2TS) through the integration of three systems to improve food safety management. The final aim is to find out the added values of the P2TS.

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