• Title/Summary/Keyword: oxygen level

Search Result 1,659, Processing Time 0.024 seconds

Effects of Hyperbaric Oxygen Treatment on the Malondialdehyde Level and Oxygen Free Radical Reactions in the Heart of the Rats Exposed to Carbon Monoxide (일산화탄소 폭로후 고압산소 투여가 흰쥐 심장에서의 malondialdehyde 함량과 산소유리기 반응에 미치는 영향)

  • 신인철;고현철;하지희
    • Biomolecules & Therapeutics
    • /
    • v.6 no.1
    • /
    • pp.9-13
    • /
    • 1998
  • ln an attempt to define the effects of hyperbaric oxygen treatment on the lipid peroxidation and oxygen See radical reactions in rats exposed to carbon monoxide, we studied malondialdehyde(MDA) level and activities of catalase and superoxide dismutase in the heart of the rats exposed to carbon monoxide. Male Sprague-Dawley albino rats weighing 240 to 260gm were used. Experimental groups consist of Control group (=breathing with air), HBO group(=exposed to hyperbaric oxygen(HBO, 3ATA, 100%) after air breath), CO group(=exposed to CO(3,970 ppm) after air breath), CO-Air group(=exposed to CO after air breath followed by air breath) and CO-HBO group(=exposed to CO after ai. breath followed HBO treatment). The CO group showed significantly higher MDA level, catalase activity and SOD activity as compared to that of control group. The CO-HBO group showed significantly lower MDA level as compared to that of CO group, and did not show significantly lower catalase activity and SOD activity as compared to that of CO group. These results suggest that the excessive oxygen free radicals is an important determinant in pathogenesis of Co-induced cardiotoxicity and HBO inhibits the lipid peroxidation caused by excessive oxygen free radicals in the heart of the rats exposed to carbon monoxide.

  • PDF

Effects of Hyperbaric Oxygen Treatment on the Malondialdehyde Level and Activities of Catalase and Superoxide Dismutase in the Kidney of the Rats Exposed to Carbon Monoxide (일산화탄소 폭로후 고압산소 투여가 흰쥐 신장에서의 malondialdehyde 함량과 catalase 및 superoxide dismutase 활성에 미치는 영향)

  • 신인철;강주섭;고현철;하지희
    • Biomolecules & Therapeutics
    • /
    • v.7 no.2
    • /
    • pp.121-126
    • /
    • 1999
  • In an attempt to define the effects of hyperbaric oxygen treatment on the lipid peroxidation and oxygen free radical reactions in rats exposed to carbon monoxide, we studied malondialdehyde (MDA) level and activities of catalase and superoxide dismutase in the kidney of the rats exposed to carbon monoxide. Male Sprague-Dawley albino rats weighing 240 to 260 gm were used. Experimental groups consist of Control group (=breathing with air), HBO group (=exposed to hyperbaric oxygen 〔HBO, 3ATA, 100%〕 after air breath), CO group (=exposed to CO〔3,970 ppm〕after air breath), CO-Air group (=exposed to CO after air breath followed by air breath) and CO-HBO group (=exposed to CO after air breath followed HBO treatment). The CO group showed significantly higher MDA level, catalase activity and SOD activity as compared to that of control group. The CO-HBO group showed significantly lower MDA level as compared to that of CO group, and did not show significantly lower catalase activity and SOD activity as compared to that of CO group. These results suggest that the excessive oxygen free radicals is an important determinant in pathogenesis of CO-induced nephrotoxicity and HBO inhibits the lipid peroxidation caused by excessive oxygen free radicals in the kidney of the rats exposed to carbon monoxide.

  • PDF

Flame Structure of Fuel-rich $CH_4/O_2/N_2$ Premixed Flame with Oxygen Enrichment (과농 조건에서 산소부화된 $CH_4/O_2/N_2$ 예혼합화염의 화염구조)

  • Lee, Ki-Yong;Kwon, Young-Suk
    • Journal of the Korean Society of Combustion
    • /
    • v.8 no.2
    • /
    • pp.1-6
    • /
    • 2003
  • Numerical simulations are conducted at atmospheric pressure in order to understand the effect of the oxygen enrichment level on structure of $CH_4/O_2/N_2$ premixed flames. Under several equivalence ratios the flame speeds are calculated and compared with those obtained from the experiments, the results of which are in good agreement. The effects of the oxygen enrichment are investigated on flames under fuel-rich conditions. As the oxygen enrichment level is increased from 0.21 to 1, the flame speed and the temperature are increased. The emission index of $CO_2$ is decreased in cases of flames for fuel rich mixtures, so the efficiency of combustion may be decreased. The maximum emission index of NO is obtained for 0.6 of the oxygen enrichment level.

  • PDF

Malondialdehyde Levels in Middle Ear Fluid from Patients of Otitis Media with Effusion

  • Mun, Kyo-Cheol;Kim, Deok-Jun
    • BMB Reports
    • /
    • v.32 no.1
    • /
    • pp.25-27
    • /
    • 1999
  • Otitis media with effusion (OME) is an inflammatory disease of the middle ear cleft. Oxygen free radicals have been implicated in a variety of inflammatory disorders. Oxygen free radicals may also be involved in the pathogenesis of OME. To evaluate the involvement of oxygen free radicals in the pathogenesis of OME, the level of malondialdehyde, which gives an index of lipid peroxidation by oxygen free radicals, was measured by the reaction with thiobarbituric acid. Malondialdehyde level in the middle ear fluid from the OME group was higher than that in the normal control group. Malondialdehyde level in the middle ear fluid from a mucoid subgroup was higher than that in the serous subgroup. Malondialdehyde levels in the middle ear fluid from the serous subgroup was significantly correlated with symptom duration. The Pearson correlation coefficient between malondialdehyde levels in the middle ear fluid from the serous subgroup and symptom duration was 0.842 (P<0.05). These results indicate that lipid peroxidation by oxygen free radicals may be involved in the pathogenesis of human OME.

  • PDF

A Study on the Development of ppb Level Dissolved Oxygen Measuring Technology using Clark Cell (Clark Cell을 이용한 ppb Level 용존산소 측정기술 개발에 관한 연구)

  • 정경열;이후락;동은석;이수태;류길수
    • Proceedings of the Korean Society of Marine Engineers Conference
    • /
    • 2001.05a
    • /
    • pp.197-201
    • /
    • 2001
  • Measuring of the dissolved oxygen is widely used for the environmental control of natural waters, sewage waste treatment, medical and biochemical studies, soil husbandry, food and drug process control, and prevention of corrosion in boilers. Especially, a power plants need special management for preventing accidents from corrosion, therefore, it is essential to measure the concentration of dissolved oxygen in real-time. In this paper we present a method of measuring dissolved oxygen very accurately up to ppb units. This method, called polarographic method, is based on the measures of the electric current generated by the oxidation process in cathode and de-oxidation process in anode, assuming that the amount of the current is proportional to the density of dissolved oxygen.

  • PDF

Effect of Oxygen Transfer Rate and Dissolved Oxygen on the Production of PHBV by Azoto-bacter vinelandii UWD. (산소전달 속도와 용존산소가 Azotobacter vinelandii UWD의 생분해성 고분자(PHBV) 생산에 미치는 영향)

  • 박창호
    • Microbiology and Biotechnology Letters
    • /
    • v.26 no.6
    • /
    • pp.529-536
    • /
    • 1998
  • In a 20 L fermentor experiments the level of dissolved oxygen (D.O.) strongly affected growth and PHBV production of Azotobacter vinelandii UWD. A higher D.O. (5%) increased specific cell growth rate two folds but PHBV production was 17 folds higher (62.3 wt%) at a lower D.O.(1%) level. D.O. level was not a good criterion to evaluate the effect of aeration on fermentation characteristics of A. vinelandii UWD. This strain maintained an equal D.O. (5%) by decreasing its oxygen consumption rate when oxygen transfer rate (OTR) was decreased by changing agitation speed at a fixed aeration rate. OTR rather than D.O. was a criterion to explain the effect of aeration on the cell growth and PHBV production. At 5% D.O. with a lower 0TR cell growth rate decreased but PHBV production (57.3 wt%) approached to that (62.3 wt%) of the lower (1%) D.O.

  • PDF

Visuospatial Cognitive Performance, Hyperoxia and Heart Rate due to Oxygen Administration (산소 공급으로 유발된 공간 인지 능력, 혈중 산소 농도, 심박동율의 변화)

  • Chung Soon Cheol;Shon Jin Hun;Lee Bongsoo;Lee Soo Yeol
    • Journal of the Korean Society for Precision Engineering
    • /
    • v.22 no.1
    • /
    • pp.193-198
    • /
    • 2005
  • Changes in visuospatial cognitive performance, blood oxygen saturation and heart rate due to the highly concentrated oxygen administration were observed in this study. Six male ($25.8 \pm$1.0) and six female (($23.8 \pm$ 1.9) adults were asked to perform 20 visuospatial tasks with the same level of difficulties by supplying two different oxygen levels (21%, 30%). Experiment consisted of Rest1 (1 min.), Control (1 min.), Task (4 min.), and Rest2 (4 min.) and physiological signals such as blood oxygen saturation and heart rate were measured through each stage. The result showed the accuracy of task performance increased significantly at 30% oxygen concentration compared with 21%, which means oxygen supply has positive effects on visuospatial cognitive performance. When 30% oxygen was supplied, blood oxygen saturation during control and task phases was increased and heart rate was decreased compared with 21%. It means that 30% oxygen can stimulate brain activities by directly increasing the actual level of blood oxygen concentration during cognitive performance, and enough oxygen supply during cognitive performance make heart rate decrease.

Low-Oxygen Atmosphere and its Predictors among Agricultural Shallow Wells in Northern Thailand

  • Wuthichotwanichgij, Gobchok;Geater, Alan F.
    • Safety and Health at Work
    • /
    • v.6 no.1
    • /
    • pp.18-24
    • /
    • 2015
  • Background: In 2006, three farmers died at the bottom of an agricultural shallow well where the atmosphere contained only 6% oxygen. This study aimed to document the variability of levels of oxygen and selected hazardous gases in the atmosphere of wells, and to identify ambient conditions associated with the low-oxygen situation. Methods: A cross-sectional survey, conducted in June 2007 and July 2007, measured the levels of oxygen, carbon monoxide, hydrogen sulfide, and explosive gas (percentage of lower explosive limit) at different depths of the atmosphere inside 253 wells in Kamphaengphet and Phitsanulok provinces. Ambient conditions and well use by farmers were recorded. Carbon dioxide was measured in a subset of wells. Variables independently associated with low-oxygen condition (<19.5%) were identified using multivariate logistic regression. Results: One in five agricultural shallow wells had a low-oxygen status, with oxygen concentration decreasing with increasing depth within the well. The deepest-depth oxygen reading ranged from 0.0% to 20.9%. Low levels of other hazardous gases were detected in a small number of wells. The low-oxygen status was independently associated with the depth of the atmosphere column to the water surface [odds ratio (OR) = 13.5 for 8-11 m vs. <6 m], depth of water (OR = 0.17 for 3-<8 m vs. 0-1 m), well cover (OR = 3.95), time elapsed since the last rainfall (OR = 7.44 for >2 days vs. <1 day), and location of well in sandy soil (OR = 3.72). Among 11 wells tested, carbon dioxide was detected in high concentration (>25,000 ppm) in seven wells with a low oxygen level. Conclusion: Oxygen concentrations in the wells vary widely even within a small area and decrease with increasing depth.

The Research on the Oxidative Stress by Free Oxygen Radicals in Sasang Constitution (활성산소(活性酸素)에 의한 산화스트레스환자의 사상체질별(四象體質別) 특성(特性)에 관한 연구(硏究))

  • Han, Kyoung-Su;Ahn, Taek-Won;Bae, Na-Young
    • Journal of Sasang Constitutional Medicine
    • /
    • v.18 no.3
    • /
    • pp.155-165
    • /
    • 2006
  • 1. Objectives The purpose of this research is to find out the Constitutional difference of Oxidative stress by Free oxygen radicals. 2. Methods We enrolled 55 patients who visited our hospital for medical examination from February 1, 2006 to May 31, 2006. This research investigated the Constitutional difference of Oxidative stress by Free oxygen radicals. 3. Results and Conclusions l) The Sasang Constitutional distribution of patients have oxidatative stress by Free oxygen radicals was Taeunmin 30%(8persons of total 27persons), Soeumin 56%(9persons of total 16persons), Soyangin 33%(4persons of total 12persons). The rate of patients have oxidatate stress was high in Soeumin. The Sasang Constitution had significance relation with oxidatative stress by Free oxygen radicals. 2) Triglyceride on the average of Taeumin patients have oxidatative stress by Free oxygen radicals is ststistical significantly higher than Triglyceride on the average of controlled normal persons in Taeumin(p-value=0.010) and Soyangin(p-value=0.015). Blood uric acid level on the average of patients have oxidatate stress by Free oxygen radicals is ststistical significantly lower than Blood uric acid level on the average of controlled normal persons in Taeumin(p-value=0.004) and Soyangin(p-value=0.037). This research has shown that there is a statistical significance between the Triglyceride level, Blood uric acid level and oxidatate stress by Free oxygen radicals.

  • PDF

A Study on the Oxygen Saturation Level Changes in the Blood Exposed to the Static Magnetic Field (자속에 노출된 인체의 혈중 산소 포화농도의 변화에 관한 연구)

  • Jung, Yong-Chul;Lee, Dong-Hoon
    • Journal of the Korean Society of Safety
    • /
    • v.22 no.6
    • /
    • pp.87-90
    • /
    • 2007
  • The effects of static magnetic field on the human biological system are becoming increasingly more important with the adaption of static magnet in the medical community. It is the goal of this paper to review the effects of static magnetic fields on oxygen saturation level in blood. The results of this paper show that the oxygen saturation level increased in the blood in index finger when the static magnetic dipole was fitted on index finger.