• Title/Summary/Keyword: oxygen administration

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Activation of Limbic Area due to Oxygen Administration during Visuospatial Task (공간 과제 수행 시 고농도 산소 공급에 의한 변연계 활성화에 관한 연구)

  • Choi, Mi-Hyun;Lee, Su-Jeong;Yang, Jae-Woong;Kim, Ji-Hye;Choi, Jin-Seung;Tack, Gye-Rae;Chung, Soon-Cheol;Kim, Hyun-Jun
    • Science of Emotion and Sensibility
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    • v.12 no.4
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    • pp.443-450
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    • 2009
  • The purpose of this study is to observe activation of limbic system during performing visuospatial tasks by 21% and 30% oxygen administration. Eight right handed male college students were selected as the subjects for this study. A visuospatial task was presented while brain images were scanned by a 3T fMRI system. The experiment consisted of two runs: one was a visuospatial task under normal air(21% oxygen) condition and the other under hyperoxic air(30% oxygen) condition. The neural activations were observed at the limbic system which is seperated 8 regions such as cingulate gyrus, thalamus, limbic lobe, hypothalamus, hippocampus, parahippocampa gyrus, amygdala, and mammiilary body. By two oxygen levels, activation areas of limbic system are almost identical. Increased neural activations were observed in the cingulate gyrus and thalamus with 30% oxygen administration compared to 21% oxygen. During 30% oxygen administration, improvement of visuospatial task performance has a relation to increase of neural activation of subcortical structures such as thalamus and cingulate gyrus as well as cerebral cortex.

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An Experimental Study on the Protective Effects of Ginseng Extract to Oxygen Toxicity (인삼의 산소중독 보호효과에 관한 실험적 연구)

  • Park, Jae-Young;Lee, Sang-Il;Yun, Dork-Ro
    • Journal of Preventive Medicine and Public Health
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    • v.22 no.2 s.26
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    • pp.208-214
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    • 1989
  • The protective effects of Panax Ginseng extract to oxygen toxicity of mice were studied under 5 ATA hyperbaric oxygen atmosphere. The findings observed are as follows: 1) Administration of Ginseng water extract manifested the prolonging survival time of mice to oxygen toxicity by hyperbaric oxygen atmosphere. After 18 hours of single Ginseng water extract administration and three days, seven days of consecutive Ginseng water extract administration showed the protective effect against oxygen toxicity. 2) Three days and seven days of consecutive Ginseng water extract administration showed the more efficient protective effect than single Ginseng Water extract administration. 3) Seven days of consecutive Ginseng water extract administration did not showed the more efficient protective effect than three days of consecutive Ginseng water extract administration.

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Studies on the Determinations of Dissolved Oxygen in Beverages (음료중 산소분석법에 관한 연구)

  • Lee, Tal-Soo;Lee, Young-Ja;Kwon, Yong-Kwan;Park, Jae-Seok;Hwang, Jung-Yun;Lee, Ju-Yeun;Song, Jee-Won;Chung, Bo-Yong;Lee, Chul-Won
    • Korean Journal of Food Science and Technology
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    • v.34 no.3
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    • pp.361-364
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    • 2002
  • This study was performed to establish a simple and accurate method for the determination of oxygen that is a processing aid in various beverage. The quantitative determination of dissolved oxygen (DO) contents in 30 cases of samples were performed by traditional titration method and polarography. As a result of the study, the analysis of DO contents in fruit-extract beverages containing oxygen by titration method was time consuming and large sample volumes were needed. Besides, serious interferences with compounds such as hydroxylamine and nitric oxide were observed, leading to false response. Although the polarography is easily affected by $H_2S$, proteins, and various organic compounds, it is a simple and practical method that provides inexpensive and relatively rapid analysis. The polarography is best suited to the routine determination of DO in a large number of samples and it is expected that the polarography can directly be applied to the quality control of the beverages containing added oxygen. The analysis results of DO contents in various fruit-extract beverages with oxygen and without oxygen were as follows: 23.10 ppm to 32.60 ppm for various frutis extract beverages with oxygen, 0.70 pp to 2.54 ppm for mixed beverages without oxygen, 7.63 ppm to 8.28 ppm for drinking water.

Effect of Highly Concentrated Oxygen Administration on Addition Task Performance and Physiological Signals (고농도 산소가 덧셈과제 수행능력과 생리신호에 미치는 영향)

  • Chung, Soon-Cheol;Lim, Dae-Woon
    • Science of Emotion and Sensibility
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    • v.11 no.1
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    • pp.105-112
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    • 2008
  • This study investigated the effect of 40% oxygen administration on the addition task performance in three levels of difficulties and physiological signals. Ten male and female college students were selected as the subjects for this study. The experiment consisted of two runs: one was a addition task, with normal air (21% oxygen) administered and the other was with hyperoxic air (40% oxygen) administered. The experimental sequence in each run consisted of Rest1 (3 min), Task1 (1 min, one digit addition task), Task2 (1 min, two digit addition task), Task3 (1 min, three digit addition task), and Rest2 (4 min). Blood oxygen saturation and heart rate were measured throughout the five phases. The accuracy rates of the addition task were enhanced with 40% oxygen administration compared to 21% oxygen. Difference in the accuracy rates grew higher with the rise of difficulty. When 40% concentration oxygen is supplied, blood oxygen saturation increased and heart rate was decreased comparing to 21%. This study showed that the supply of high concentration oxygen increases blood oxygen saturation, which in turns accelerates brain activation resulting from cognitive process and enhances arithmetic abilities. Particularly when difficulty is high, demand for oxygen increases and, as a result, the effect of high concentration oxygen becomes more significant.

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Differences of Blood Oxygen Saturation between Male and Female due to Change of Supply Rate of Highly Concentrated Oxygen (고농도 산소 공급량 변화에 따른 남/녀 혈중 산소 포화도의 차이)

  • Yi, Jeong-Han;Choi, Mi-Hyun;Kim, Ji-Hye;Lee, Su-Jeong;Yang, Jae-Woong;Chung, Soon-Cheol;Lim, Dae-Woon;Lee, Dong-Hyung;Min, Byung-Chan
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.32 no.4
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    • pp.203-207
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    • 2009
  • The purpose of this study was to examine differences between male and female in blood oxygen saturation due to 93% oxygen administration of the three levels (1L/min, 3L/min, 5L/min). Ten healthy male ($25.0{\pm}1.8$ years) and ten female ($23.7{\pm}1.9$ years) college students were selected as the subjects for this study. The experiment consisted of three runs, i.e., the three levels of 93% oxygen administration, respectively. The each run consisted of three phases, i.e., Rest 1 (5 min), Hyperoxia (10 min), and Rest 2 (5 min). Blood oxygen saturation were measured throughout the three phases. By increasing the supply rate of highly concentrated oxygen, rising rate of blood oxygen saturation was increased. Blood oxygen saturation of female was higher than male regardless of supply rate of highly concentrated oxygen and phases.

Development of Nursing Practice Guidelines for Non-humidified Low Flow Oxygen Therapy by Nasal Cannula (비강 캐뉼라를 이용한 저유량 산소 요법에서 비가습 적용의 간호실무 가이드라인 개발)

  • Nam, Ae-Ri-Na;Bae, Woo-Hyun;Park, Mi-Mi;Ko, Eun-Jeong;Park, Byung-Nam;Park, Jeong-Ok;Yim, Ji-Yeoung
    • Journal of Korean Academy of Nursing Administration
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    • v.19 no.1
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    • pp.87-94
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    • 2013
  • Purpose: The purpose of this study was to provide a basis for non-humidified low flow oxygen by nasal cannula and to provide a guide for consistent care in nursing practice. Methods: A methodological study on the development of guidelines with experts' opinions on collected items, framing PICO questions, evaluating and synthesizing texts which were searched with the key words (low flow oxygen, nasal cannula, humidification of oxygen, guideline) from web search engines. Results: Of the 45 researched texts on the web, 9 texts relevant to the theme were synthesized and evaluated. All patients with humidified or non-humidified oxygen therapy reported that they had no discomfort. Conclusion: The results indicate that there are no tangible grounds for patients' perceived differences between the humidified and non-humidified oxygen under 4L/min supplied by nasal cannula. with oxygen. Therefore, non-humidification oxygen therapy is strongly advised when suppling under 4L/min oxygen by nasal cannula (recommended grade A).

Visuospatial Cognitive Performance Following Oxygen Administration in Healthy Young Men (고농도 산소 공급에 따른 젊은 성인 남자의 공간지각 능력 변화)

  • Chung, S.C.;Tack, G.R.;Yi, J.H.;Sohn, J.H.
    • Journal of Korean Institute of Industrial Engineers
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    • v.30 no.1
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    • pp.11-16
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    • 2004
  • Oxygen is an essential element for human beings' physical and mental activities, and in particular, plays an important role in brain functions. The present study attempted to investigate the effects of supply of highly concentrated (30%) oxygen on human ability of visuospatial cognition, compared to air of normal oxygen concentration (21%). This study sampled eight male university students (the average age: 23.5) as subjects. An equipment that supplies 21% and 30% oxygen at a constant rate of 8L/min was developed. Two types of questionnaire containing 20 questions were developed to measure the ability of visuospatial cognition, and accuracy and reaction time were calculated from the result of task performance. The average accuracy was $50.63{\pm}8.63$ [%] and $62.50{\pm}9.64$[%] for 21%and 30% oxygen respectively, and a statistically significant difference was found in the accuracy between the two types of oxygen. The average reaction time was $6.60{\pm}O.77$ [sec] and $7.23{\pm}0.69$ [sec] for 21%and 30% oxygen respectively, and a statistically significant difference was not found in the reaction time. The results showed that there is no difference in the average reaction time but the average accuracy rises with the supply of highly concentrated (30%) oxygen, indicating that the supply of highly concentrated oxygen has a partially positive effect on the ability of visuospatial cognition.

The effects of Seungmagalgeuntang-gamibang on the anti-allergic and immune response to mice (升麻葛根湯加味方이 마우스의 抗 ALLERGY 및 免疫反應에 미치는 影響)

  • Kim, Nam-Kwen;Hwang, Chung-Yeon;Lim, Gyu-Sang
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.8 no.1
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    • pp.1-19
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    • 1995
  • Seungmagalgeuntang-gamibang has long been known to have anti-allergic effect. However, the mechanism of action of Seungmagalgeuntang-gamibang is not well investigated. The author analysed the effects of Seungmagalgeuntang-gamibang on the vascular permeability, delayed-type and contact hypersensitivities, and phagocytic function, the results obtained are as follows: 1. Administration of Seungmagalgeungtang-gamibang decreased the vascular permeability induced by serotonin in the mouse. 2. Administration of Seungmagalgeuntang-gamibang decreased the vascular permeability induced by histamine without statistical significant. 3. Administration of Seungmagalgeuntang-gamibang decreased the delayed-type hypersensitivity induced by sheep red blood cells. 4. Administration of Seungmagalgeungtang-gamibang decreased the contact hypersensitivity induced by dinitrochlorobenzene. 5. Seungmagalgeungtang-gamibang increased the phagocytic-activities of macrophages in vitro and in vivo. 6. Seungmagalgeungtang-gamibang enhanced the formation of reactive oxygen intermediates in vitro and in vivo. The above results demonstrate that Seungmagalgeuntang-gamibang suppresses the hypersensitivity reactions with increasing the phagocytic functions and formations of reactive oxygen intermediates from macrophages.

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A Molecular Dynamics Study of the Interaction of Oxygen Molecules with a Water Droplet

  • Ambrosia, Matthew Stanley
    • Journal of Environmental Science International
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    • v.27 no.10
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    • pp.901-906
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    • 2018
  • Water and oxygen are two of the most essential molecules for many species on earth. Their unique properties have been studied in many areas of science. In this study, the interaction of water and oxygen molecules was observed at the nano-scale. Using molecular dynamics, a water droplet with 30,968 water molecules was simulated. Then, 501 oxygen molecules were introduced into the domain. A few oxygen molecules were attracted to the surface of the water droplet due to van der Waals forces, and some oxygen molecules actually entered the water droplet. These interactions were visualized and quantified at four temperatures ranging from 280 to 370 K. It was found that at high temperatures, there was a higher possibility of the oxygen molecules penetrating the water droplet than that at lower temperatures. However, at lower temperatures, oxygen molecules were more likely to be found interacting at the surface of the water droplet than at high temperatures.