• 제목/요약/키워드: overall time

검색결과 6,235건 처리시간 0.038초

Clinical Outcomes of Gamma Knife Radiosurgery for Metastatic Brain Tumors from Gynecologic Cancer : Prognostic Factors in Local Treatment Failure and Survival

  • Shin, Hong Kyung;Kim, Jeong Hoon;Lee, Do Heui;Cho, Young Hyun;Kwon, Do Hoon;Roh, Sung Woo
    • Journal of Korean Neurosurgical Society
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    • 제59권4호
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    • pp.392-399
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    • 2016
  • Objective : Brain metastases in gynecologic cancer (ovarian, endometrial, and cervical cancer) patients are rare, and the efficacy of Gamma Knife Radiosurgery (GKRS) to treat these had not been evaluated. We assessed the efficacy of GKRS and prognostic factors for tumor control and survival in brain metastasis from gynecologic cancers. Methods : This retrospective study was approved by the institutional review board. From May 1995 to October 2012, 26 women (mean age 51.3 years, range 27-70 years) with metastatic brain tumors from gynecologic cancer were treated with GKRS. We reviewed their outcomes, radiological responses, and clinical status. Results : In total 24 patients (59 lesions) were available for follow-up imaging. The median follow-up time was 9 months. The mean treated tumor volume at the time of GKRS was $8185mm^3$ (range $10-19500mm^3$), and the median dose delivered to the tumor margin was 25 Gy (range, 10-30 Gy). A local tumor control rate was 89.8% (53 of 59 tumors). The median overall survival was 9.5 months after GKRS (range, 1-102 months). Age-associated multivariate analysis indicated that the Karnofsky performance status (KPS), the recursive partitioning analysis (RPA) classification, and the number of treated lesions were significant prognostic factors for overall survival (HR=0.162, p=0.008, HR=0.107, p=0.038, and HR=2.897, p=0.045, respectively). Conclusion : GKRS is safe and effective for the management of brain metastasis from gynecologic cancers. The clinical status of the patient is important in determining the overall survival time.

건조 감귤의 제조조건 최적화 (Optimization on Preparation Conditions of Dried Citrus)

  • 이기동;윤성란
    • 한국식품영양과학회지
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    • 제32권8호
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    • pp.1297-1301
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    • 2003
  • 감귤의 건조에 따른 품질 특성을 모니터링하고 기호도가 우수한 건조 감귤을 제조하고자 건조온도 및 건조시간에 대한 중심합성실험 계획으로 반응표면분석을 실시하였다. 그 결과 수분활성도, 경도(hardness) 및 부드러움 정도(softness)는 건조온도에 영향을 많이 받는 것으로 나타났다. 건조 감귤의 건조온도가 증가할수록 수분 활성도는 감소하는 것으로 나타났으며, 경도는 증가하는 것으로 나타났다. 부드러움 정도는 건조 온도가 낮고 건조시간이 짧을수록 높게 나타났다. 건조감귤의 전반적인 기호도는 건조온도가 낮을수록 높은 기호도를 가지는 것으로 나타났다. 높은 기호도를 가지는 범위에서의 경도는 2.01 ∼ 3.20 ${\times}$ $10^{6}$ dyn/$\textrm{cm}^2$, 부드러움 정도는 62.54 ∼ 146.37 cm/kg의 범위로 나타났다. 이러한 범위를 만족시켜주는 건조 조건범위는 건조온도 66 ∼ 75$^{\circ}C$ 및 건조시간 8 ∼ 14 hr범위였다.

제조 방법을 달리한 당근 정과의 품질 특성 (Quality Characteristics of Jungkwa Made with Carrot, using Different Manufacturing Methods)

  • 김현아;이경희
    • 동아시아식생활학회지
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    • 제24권2호
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    • pp.242-251
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    • 2014
  • The traditional food - jungkwa of Korea, is difficult to manufacture. In this study, jungkwa with carrots was made in a rice cooker to simplify preparation. The boiling times for red color, chewiness and overall acceptability of jungkwa with carrots in a rice cooker as compared to the traditional method were 135 minutes, 150 minutes, 165 minutes, 180 minutes and 195 minutes, respectively. The rice cooker produced a lower moisture content in jungkwa with carrots when cooked for a longer time period, whereas the sugar content increased significantly. The color value of jungkwa with carrots was reduced at a longer boiling time as compared to the traditional method, yellowness increased when boiling time was longer than 195 minutes, whereas it remained the same with the traditional method. The hardness of jungkwa with carrots increased and candied jungkwa's result increased significantly when the boiling time was longer than 165 minutes. The rice cooker created a similar chewiness even when boiling time was over 165 minutes, although not consistently. The sensory evaluation scores of jungkwa made with carrots in terms of appearance, smell, taste, texture and overall preference were highest at 150 minutes and 165 minutes. Boiling jungkwa for 150 minutes in the rice cooker is the traditional method which simmers jungkwa at a lower timethan the preference time. Therefore, the best time for boiling jungkwa in the rice cooker highest was 165 minutes. After storage for 15 days chewiness and moisture content of jungkwa made with carrots at different boiling times, increased and decreases respectively. Therefore, the rice cooker can used to achieve comparable jungkwa without the traditional method.

Age and Survival of Cervical Cancer Patients with Bone Metastasis

  • Nartthanarung, Adisak;Thanapprapasr, Kamolrat;Udomsubpayakul, Umaporn;Thanapprapasr, Duangmani
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권19호
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    • pp.8401-8404
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    • 2014
  • Background: To determine survival times of cervical cancer patients with bone metastasis related to the effect of age at the time of cervical cancer diagnosis, we performed the retrospectively analytical study. Methods: A total of 68 cervical cancer patients with bone metastasis were treated at a single hospital, during January 1998 to December 2010. Fifty-two medical records were identified and collected, the remaining sixteen medical records were not found. Main outcome measures were patient characteristics, clinical information, duration from cervical cancer diagnosis to bone metastasis diagnosis, survival time after bone metastasis and overall survival time. Results: Among fifty-two cervical cancer patients with bone metastasis, there were 13 patients who were less than 45 years old, and 39 patients were 45 years old or more at the time of cervical cancer diagnosis. The younger group had less median overall survival than the older group, with a statistically significant difference (21 months, 95% CI 19.93-22.06; 34 months, 95% CI 23.27-44.72, p = 0.021). However, they were comparable in the duration from cervical cancer diagnosis to bone metastasis diagnosis and the survival time after bone metastasis. Conclusion: Young patients with bone metastasis aged less than 45 years old at the time of cervical cancer diagnosis have a poorer prognosis than the elderly patients. Impact: To improve survival and quality of life, more intensive and novel multimodal treatments at the time of cervical cancer diagnosis should be considered in patients less than forty-five years, who can tolerate the side effects better.

반응표면분석을 이용한 데리야끼소스의 최적화에 관한 연구 (A Study on the Optimization of Teriyaki Sauce by RSM(Response Surface Methodology))

  • 김현아;정현아;송청락
    • 한국조리학회지
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    • 제17권5호
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    • pp.206-217
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    • 2011
  • 본 연구는 설탕 간장을 주로 사용하는 데리야끼소스의 간장, 설탕, 가열시간의 최적화를 구하고자 하였다. 연구 결과를 요약하면 다음과 같다. 간장, 설탕, 가열시간을 독립변수로 하여 관능검사를 실사하였다. 관능검사결과 외관, 맛, 전반적인 기호도에서 유의적으로 차이를 보였고, 소스의 외관에는 가열시간이 가장 큰 영향을 미쳤고, 맛은 설탕, 가열시간, 간장순으로 영향을 미쳤으며, 전반적인 기호도는 간장, 가열시간, 설탕순으로 영향을 미쳤다. 종합하면 간장은 1,182.76 g -1,210.11 g, 설탕은 843.97 g - 851.17 g, 가열시간은 174.49 분 - 181.46 분의 범위에서 데리야끼소스를 제조함이 좋은 것으로 나타났고, 최적은 간장 1,196.44 g, 설탕은 847.57 g, 가열시간은 177.98 분으로 하여 데리야끼소스를 제조함이 적당한 것으로 나타났다.

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A Time-Domain Method to Generate Artificial Time History from a Given Reference Response Spectrum

  • Shin, Gangsig;Song, Ohseop
    • Nuclear Engineering and Technology
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    • 제48권3호
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    • pp.831-839
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    • 2016
  • Seismic qualification by test is widely used as a way to show the integrity and functionality of equipment that is related to the overall safety of nuclear power plants. Another means of seismic qualification is by direct integration analysis. Both approaches require a series of time histories as an input. However, in most cases, the possibility of using real earthquake data is limited. Thus, artificial time histories are widely used instead. In many cases, however, response spectra are given. Thus, most of the artificial time histories are generated from the given response spectra. Obtaining the response spectrum from a given time history is straightforward. However, the procedure for generating artificial time histories from a given response spectrum is difficult and complex to understand. Thus, this paper presents a simple time-domain method for generating a time history from a given response spectrum; the method was shown to satisfy conditions derived from nuclear regulatory guidance.

대형할인매장 이용자의 충동구매에 관한 연구 (A Study on the Impulse Buying of Large Discount Store Consumers)

  • 김수영;유두련
    • 가정과삶의질연구
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    • 제19권1호
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    • pp.95-110
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    • 2001
  • Recently a number of large discount store and those of its users was increasing. The purpose of this study is to investigate the tendency of impulse buying and analyzes factors which influence impulse buying. The data had been collected from questionaries with 474 consumers who visit large discount store. The major statistical methods used for data analysis are frequency, percentile, mean, t-test, multiple regression analysis, one-way ANOVA, and Duncans multiple range test utilizing SPSS Win pc+program. The results of this study are as follows : 1. The four different kind of impulse buying is measured. The overall level of impulse buying is 2.76. Suggestion impulse buying(M=3.19) is the highest, and the lowest is pure impulse buying(M=2.66). 2. In the area of demographic variables is significantly different in the age of twenties and thirties(p<.05). A visit frequency and membership. In the area of in-store variables is significantly different by all factors at impulse buying except waiting time. Especially, point-of-purchase(POP) advertisement and discount sale are very important variables. A visit frequency and membership are significantly different in the area of consumer-related variables. 3. Waiting time, a visit frequency, a POP advertisement, and a discount sale have the positive effects on overall impulse buying. Pure impulse buying is influenced by shopping list, POP advertisement and a stores atmospher. Buying companion, membership, kind of store and waiting time have the effect on reminder impulse buying. Suggestion impulse buying is influenced by school career, shopping list and POP advertisement. Planned impulse buying is influenced by sex, POP advertisement, buying companion and discount sale.

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혼합보증이 종료된 이후의 비용과 비가동시간에 근거한 보전정책 (Maintenance Policy Based on Cost and Downtime Following the Expiration of Combination Warranty)

  • 정기문
    • Communications for Statistical Applications and Methods
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    • 제15권6호
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    • pp.909-923
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    • 2008
  • 본 논문에서는 수리가 가능한 시스템에 대하여 혼합보증이 종료된 이후의 교체모형과 예방보전모형을 고려하는데, 만약 보증기간이 종료된 이후에 시스템에 고장이 발생하면 최소수리를 수행한다. 최적의 교체정책과 최적의 예방보전정책을 결정하기 위한 기준으로는 기대비용과 기대비가동시간에 근거한 총밸류함수를 사용한다. 그리고 시스템의 고장시간이 와이블분포를 할 때 수치적 예를 통해서 제안된 최적의 교체정책 및 예방보전정책을 자세히 설명하고자 한다.

Concurrent Channel Time Allocation for Resource Management in WPANs

  • Park, Hyunhee;Piamrat, Kandaraj;Singh, Kamal Deep
    • Journal of information and communication convergence engineering
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    • 제12권2호
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    • pp.109-115
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    • 2014
  • This paper presents a concurrent channel time allocation scheme used in the reservation period for concurrent transmissions in 60-GHz wireless personal area networks (WPANs). To this end, the proposed resource allocation scheme includes an efficient method for creating a concurrent transmission group by using a table that indicates whether individual streams experience interference from other streams or not. The coordinator device calculates the number of streams that can be concurrently transmitted with each stream and groups them together on the basis of the calculation result. Then, the coordinator device allocates resources to each group such that the streams belonging to the same group can transmit data concurrently. Therefore, when the piconet coordinator (PNC) allocates the channel time to the individual groups, it should allow for maximizing the overall capacity. The performance evaluation result demonstrates that the proposed scheme outperforms the random grouping scheme in terms of the overall capacity when the beamwidth is $30^{\circ}C$ and the radiation efficiency is 0.9.

Some Phonetic Characteristics of Mid-vocalic Lax Stops and Pre/Post-stop Vowels in Korean

  • Kim, Dae-Won
    • 음성과학
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    • 제5권2호
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    • pp.17-26
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    • 1999
  • It has been claimed that Korean mid-vocalic voiceless unaspirated lax stops are phonetically realized with voicing throughout the oral closure phase. Acoustic measurements were undertaken to examine the claim with four Korean native speakers using /$V_1CV_2$/ words where the vowel ($V_1\;=\;V_2$) was /i, a, u/ and the C was voiceless unaspirated lax stops /p, t, k/. Findings: (1) During mid-vocalic stops /k/ and /p/ the vowel /u/ was accompanied generally by a significant increase in voice cessation time as percentage of the oral closure interval (PCT) than the vowel /a/, regardless of subjects, whereas in mid-vocalic alveolar stop /t/ the effects of vowels on PCT were subject-dependent, (2) The effects of vowels on PCT were significantly greater in mid-vocalic /k/ than /p/, regardless of subjects, (3) The mean PCT, averaged across six tokens, ranged from 17% to100%, giving overall mean 61% in which the standard deviation was ${\pm}30$, and (4) Overall % of the total of mid-vocalic unaspirated lax stops were produced with a substantial period of devocing and voicing lag. Considering these results, it is difficult to agree with the existing claims that Korean voiceless unaspirated lax stops are phonetically realized with voicing throughout the oral closure phase. Other phonetic variables, including the durations of pre/post-stop vowels, voice onset time, voice cessation time, and the duration of oral closure, were measured.

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