• Journal of Korean Neurosurgical Society
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• 제62권3호
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• pp.321-327
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• 2019

Focal cortical dysplasia (FCD) is the major cause of intractable focal epilepsy in childhood leading to epilepsy surgery. The overall seizure freedom after surgery ranges between 50-75% at 2 years after surgery and the long-term seizure freedom remain relatively stable. Seizure outcome after surgery depends on a various factors such as pathologic etiologies, extent of lesion, and types of surgery. Therefore, seizure outcome after surgery for FCD should be analyzed carefully considering cohorts' characteristics. Studies of pediatric epilepsy surgery emphasize the early surgical intervention for a better cognition. Early surgical intervention and cessation of seizure activity are important for children with intractable epilepsy. However, there are limited data on the cognitive outcome after surgery in pediatric FCD, requiring further investigation. This paper reviews the seizure and cognitive outcomes of epilepsy surgery for FCD in children. Several prognostic factors influencing seizure outcome after surgery will be discussed in detail.

• 한국중재학회지:중재연구
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• 제32권4호
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• pp.87-101
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• 2022

Since Research and Development has been expanded by government, It is very important to evaluate the outcome of Research and Development. Government have levied the penalty of researchers who misused research funding as time goes on. However, there is no protect law for the research before 2021. Government put new committee for the researchers to judge whether their action is legal or illegal based of Innovation Act 2021. Due to the various outcome index of research and development, many firms which is paticipating the research and development have been confused the outcome index. Also, It is difficult for government agencies for management to evaluate the outcome. Even if the committee is trying to solve dispute between researchers and the government agencies, it is not enough to solve it. Therefore, we need to consider Alternative Dispute Resolution(ADR), because the ADR has been developved detail skills for long time.

• Educational Technology International
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• 제12권2호
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• pp.1-18
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• 2011

This study intends to examine the effects of motivational scaffolding in Computer-Supported Collaborative Learning (CSCL). This study was focused on the following two questions. Do motivational scaffolding lead to positive effects on the process in CSCL? Do motivational scaffolding lead to positive effects on the outcome in CSCL? In order to identify strategies for motivational scaffolding, we reviewed the "Flow Theory." Based on literature reviews, principles and strategies were drawn for the motivational scaffolding. An experimental study was conducted in order to investigate the effects of motivational scaffolding on process and outcome. In this study, 87 undergraduate students were divided into two different groups (control group, experimental group). Motivational scaffolding was provided to experimental group. The process was analyzed by examining learners' satisfaction in process. The outcome was analyzed by examining learners' satisfaction in product, group coherence, and quality of product. The difference between the two groups was statistically significant. From these results, we concluded that motivational scaffolding led to positive effects on process and outcome in CSCL environment.

• 대한족부족관절학회지
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• 제10권1호
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• pp.1-6
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• 2006

Purpose: To evaluate the clinical manifestations, the patterns and the functional outcome of the amputations due to the diabetic foot complications. Materials and Methods: Fifty patients (50 feet) of diabetic foot amputations were followed for more than 1 year. The mean age was 62.5 years, and the mean follow-up period was 46 months. Retrospective analysis was performed using chart review and interview with the patients. The outcome was assessed with modified AOFAS scale. Results: The diabetic foot lesions were infection in 45 feet, gangrene in 35 feet and ulcer in 15 feet. Toe amputation was most commonly performed procedure (23 cases) followed by below knee and ray amputation. Postoperative modified AOFAS score was average 51.5 points, and 94% were satisfied with outcome. Minor amputations showed better outcome than the major amputations. Conclusion: Overall postoperative functional outcome was encouraging with high patient satisfaction rate (94%). Better outcome was obtained with the minor amputations.

• 한국간호교육학회지
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• 제20권3호
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• pp.392-401
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• 2014

Purpose: The purpose of this study was to examine the mediating effects of alcohol outcome expectancy and depression on the relation between parents' problematic drinking and their collegiate children's problematic drinking. Methods: This study was conducted using a descriptive survey design. Subjects were 342 university students from three universities in Gwangju city and Jeollanamdo. Data were collected from November to December 2013 using self-report questionnaires. Data were analyzed using SPSS 19.0. Results: Of the participants, 31.0% were in the adult children of alcoholics (ACOA) group. The ACOA group scored significantly higher on problem drinking, alcohol outcome expectancy, and depression measures than did the non-ACOA group. There were significant positive correlations between parent problematic drinking and university students' alcohol outcome expectancy, depression and, problematic drinking. It was also found that alcohol outcome expectancy partially mediated the relationship between parent problematic drinking and their children's problematic drinking. This was not found for depression. Conclusions: Based on the present findings, nursing interventions should be developed to decrease alcohol outcome expectancy, with additional consideration regarding depression, in order to prevent problematic drinking among ACOA.

• 성인간호학회지
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• 제24권6호
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• pp.580-587
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• 2012

Purpose: To develop and test the validity and reliability of the Korean version of outcome expectations-2 for exercise. Methods: The Korean version of outcome expectations for exercise-2 was developed through forward-backward translation techniques. Content, criterion, and construct validity using confirmatory factor analysis and an internal consistency reliability were conducted. Survey data were collected from 200 older adults living in a community. Results: The Korean version of outcome expectations for exercise-2 had factor loadings of the 13 items ranged from .20 to .76, and was validated by confirmatory factor analysis (CFI=.829, NFI=.754, RMSEA=.086). Also there was a reliable internal consistency with a Cronbach's ${\alpha}$ for the positive domain of outcome expectations for exercise scale-2 of .73. Negative domain, however, reported slightly low Cronbach's ${\alpha}$ of .63. Conclusion: The findings of this study demonstrated that the Korean version of outcome expectations for exercise-2 had satisfactory validity to measure expectations regarding exercise among older adults in Korea. Negative domain, however, should be retested to verify reliability for the further study.

• Journal of Korean Neurosurgical Society
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• 제50권5호
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• pp.403-408
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• 2011

Objective : Contrary to some clinical belief, there were quite a few studies regarding animal models of intracerebral hemorrhage (ICH) $in$ $vivo$ suggesting that prior use of statins may improve outcome after ICH. This study reports the effect of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG CoA) reductase inhibitor, simvastatin given before experimental ICH. Methods : Fifty-one rats were subjected to collagenase-induced ICH, subdivided in 3 groups according to simvastatin treatment modality, and behavioral tests were done. Hematoma volume, brain water content and hemispheric atrophy were analyzed. Immunohistochemical staining for microglia (OX-42) and endothelial nitric oxide synthase (eNOS) was performed and caspase-3 activity was also measured. Results : Pre-simvastatin therapy decreased inflammatory reaction and perihematomal cell death, but resulted in no significant reduction of brain edema and no eNOS expression in the perihematomal region. Finally, prior use of simvastatin showed less significant improvement of neurological outcome after experimental ICH when compared to post-simvastatin therapy. Conclusion : The present study suggests that statins therapy after ICH improves neurological outcome, but prior use of statins before ICH might provide only histological improvement, providing no significant impact on neurological outcome against ICH.

• Journal of Korean Neurosurgical Society
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• 제52권5호
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• pp.466-471
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• 2012

Objective : The aim of this study was to devise an objective clustering method for magnetoencephalography (MEG) interictal spike sources, and to identify the prognostic value of the new clustering method in adult epilepsy patients with cortical dysplasia (CD). Methods : We retrospectively analyzed 25 adult patients with histologically proven CD, who underwent MEG examination and surgical resection for intractable epilepsy. The mean postoperative follow-up period was 3.1 years. A hierarchical clustering method was adopted for MEG interictal spike source clustering. Clustered sources were then tested for their prognostic value toward surgical outcome. Results : Postoperative seizure outcome was Engel class I in 6 (24%), class II in 3 (12%), class III in 12 (48%), and class IV in 4 (16%) patients. With respect to MEG spike clustering, 12 of 25 (48%) patients showed 1 cluster, 2 (8%) showed 2 or more clusters within the same lobe, 10 (40%) showed 2 or more clusters in a different lobe, and 1 (4%) patient had only scattered spikes with no clustering. Patients who showed focal clustering achieved better surgical outcome than distributed cases (p=0.017). Conclusion : This is the first study that introduces an objective method to classify the distribution of MEG interictal spike sources. By using a hierarchical clustering method, we found that the presence of focal clustered spikes predicts a better postoperative outcome in epilepsy patients with CD.

• Journal of Korean Neurosurgical Society
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• 제56권4호
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• pp.303-309
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• 2014

Objective : The purpose of this study was to retrospectively review cases of intracerebral hemorrhage (ICH) medically treated at our institution to determine if the CT angiography (CTA) 'spot sign' predicts in-hospital mortality and clinical outcome at 3 months in patients with spontaneous ICH. Methods : We conducted a retrospective review of all consecutive patients who were admitted to the department of neurosurgery. Clinical data of patients with ICH were collected by 2 neurosurgeons blinded to the radiological data and at the 90-day follow-up. Results : Multivariate logistic regression analysis identified predictors of poor outcome; we found that hematoma location, spot sign, and intraventricular hemorrhage were independent predictors of poor outcome. In-hospital mortality was 57.4% (35 of 61) in the CTA spot-sign positive group versus 7.9% (10 of 126) in the CTA spot-sign negative group. In multivariate logistic analysis, we found that presence of spot sign and presence of volume expansion were independent predictors for the in-hospital mortality of ICH. Conclusion : The spot sign is a strong independent predictor of hematoma expansion, mortality, and poor clinical outcome in primary ICH. In this study, we emphasized the importance of hematoma expansion as a therapeutic target in both clinical practice and research.

• 의학교육논단
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• 제15권3호
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• pp.144-150
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• 2013

Before Outcome-based curriculum reform, medical graduate school and medical schools of korea need to understand limit or threshold of outcome-based education's point of view. This article examines the multi-dimensional concept of competence suggested by Stoof and colleagues and discusses about implication for outcomebased education in medical education of Korea. Because Stoof and colleagues's five dimensions of competence reveal various concepts and educational methods of competence. Therefore, It is possible to use to identify the strengths and weaknesses of outcome-based education of Korea as a reference standard. Five dimensions of competence suggested by Stoof and colleagues is consist of 'personal vs. task characteristics,' 'individual vs. distributed competence,' 'specific vs. general competence,' 'levels of competence vs. competence as a level,' and 'teachable vs. non-teachable.' Implication for outcome-based education in medical education of Korea is, first, that It should recognize to outcome-based education as a one of educational models approaching to competence. Second, discussion about competence should be expanded from pre-medical education to graduated medical education and continuing medical education.