• 대한수의학회지
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• 제37권4호
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• pp.809-816
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• 1997

In this presented study, we established a method for diagnosis of porcine epidemic diarrhea(PED) by in situ hybridization(ISH), which made distinct progress in diagnostic pathology. We also carried out the retrospective diagnosis through ISH to assume the exact time of the first outbreak and incidence of PED in Korea. The outbreak of PED in Korea reported in 1992. However, since the end of 1980's, some researches of pig-industry have already suspected the outbreak of PED, not transmissible gastroenteritis(TGE). In this experiment, we performed the ISH using 80 formalin-fixed and paraffin-embedded tissues of porcine intestine which were requests for pathological diagnosis from 63 farms whose primary sign was diarrhea from 1984 to 1991. We prepared biotinylated cDNA probe(492base pairs) for ISH by nick translation method and carried out the ISH, using $Microprobe^{TM}$ capillary action system(Fisher $Biotech^R$). We detected PED virus in intestinal mucosa of 2 cases in 1992, 1 case in 1988, and 1 case in 1987. As a result, we assume that the outbreak of PED in Korea have already started since 1987.

• Environmental Engineering Research
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• 제20권1호
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• pp.59-63
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• 2015

About 4,500 mass burial sites of carcasses from the 2010/2011 outbreak of Foot-and-Mouth (FMD) disease in Korea show very slow stabilization speed, although more than 3 years have passed. Therefore, a plan is being considered to boost the speed of stabilization or removal. This is a study on the social value of the removal plan for 4,500 mass burial sites from the 2010/2011 outbreak of FMD in Korea. This valuation is based on the survey of 1,000 people living all over Korea. Korean people have a willingness to pay 101.2 billion Korean Won (about US $100 million). This value is a large amount, but it is small compared to the cost of a FMD outbreak. The cost for the Korean government from 5 outbreaks since 2000 ranged from 28.8 billion Won to 3.2 trillion Won. These were the costs only paid by the Korean government. One estimate reported that there would be a total damage of 1.4 trillion Won, if FMD outbreak occurs in Jeju Islands, a small part of Korea. If burial sites have very slow stabilization speed and some hazardous contents, the social damage will exceed the removal cost.

• Journal of Preventive Medicine and Public Health
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• 제48권6호
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• pp.265-270
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• 2015

The recent Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak has originated from a failure in the national quarantine system in the Republic of Korea as most basic role of protecting the safety and lives of its citizens. Furthermore, a number of the Korean healthcare system's weaknesses seem to have been completely exposed. The MERS-CoV outbreak can be considered a typical public health crisis in that the public was not only greatly terrorized by the actual fear of the disease, but also experienced a great impact to their daily lives, all in a short period of time. Preparedness for and an appropriate response to a public health crisis require comprehensive systematic public healthcare measures to address risks comprehensively with an all-hazards approach. Consequently, discussion regarding establishment of post-MERS-CoV improvement measures must focus on the total reform of the national quarantine system and strengthening of the public health infrastructure. In addition, the Korea Centers for Disease Control and Prevention must implement specific strategies of action including taking on the role of "control tower" in a public health emergency, training of Field Epidemic Intelligence Service officers, establishment of collaborative governance between central and local governments for infection prevention and control, strengthening the roles and capabilities of community-based public hospitals, and development of nationwide crisis communication methods.

• 셀메드
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• 제10권4호
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• pp.29.1-29.6
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• 2020

COVID-19 (Corona Virus Disease-2019) is an infectious respiratory disease caused by the most recently discovered coronavirus, SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona virus-2). This new viral disease was unknown before the outbreak began in Wuhan, China, in December 2019. As of November 16th 2020, it affects about 54.3 million populations, death troll increased to 1.32 million cases in worldwide. Whereas in India 8.85 cases are infected with COVID-19, of which 1, 30, 112 cases were died. Till now there has been no specific anti-virus drug or vaccines are available for the treatment of this disease, the supportive care and non-specific treatment to the symptoms of the patient are the only options in Biomedicine, the entire world turns its attention towards alternative medicine or Traditional medicine. Siddha medicine is one of the primordial systems of medicine practiced in the southern part of India, it dealt a lot about pandemic, and its management. This review provides an insight into Pandemic in Siddha system and its management in both ancient history and modern history, National and state level Government policies related to current pandemic, World Health Organization (WHO) guidelines on usage of unproven drug during infectious disease outbreak, Preparedness of Siddha system during a pandemic outbreak Challenges and Recommendations.

• 대한수의학회지
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• 제47권4호
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• pp.429-435
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• 2007

The risk of an outbreak of classical swine fever (CSF) was evaluated in relation to the vaccination and seroprevalence of antibodies. Blood samples were collected from 60 piggeries throughout Korea and information regarding CSF vaccination habits was also obtained via in-person interviews with pig farmers. The results of the survey indicated that 51 out of 60 farms were regularly performing CSF vaccinations in reproductive herds. Farmers preferred to vaccinate their reproductive pigs before weaning (41 farms) than on (9 farms) or after weaning (1 farm). In growing herds, however, double vaccinations as recommended were implemented for only 40 farms (66.7%) and vaccine schedules were identified as being frequently ignored. Moreover, many farms (18/40) were found to vaccinate earlier or later than the recommended time. According to antibody seroprevalence levels, only 36 farms (60%) were considered to be safe regarding potential risk for a CSF outbreak. Among the remaining pig farms, 6 were at low-risk (10%), 12 were at medium-risk (20%), and another 6 were at high-risk (10%). Antibody levels were found to be consistent with vaccination status obtained from personal interview surveys. Our findings demonstrate the importance of vaccinations regarding the prevention of a CSF outbreak, suggesting that vaccinations must be promoted toward pig raisers and practitioners.

• 한국임상수의학회지
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• 제29권5호
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• pp.395-399
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• 2012

2011년 경북 영주의 여러 농가에서 이병율과 치사율이 높은 소 바이러스성 설사 바이러스(BVDV)가 발생하였다. 유전자 분석 결과 두 개의 유전자형 BVDV-1b (n = 21)와 BVDV-2a (n = 7)이 확인되었다. 검사결과, 이 지역의 농가에서는 BVDV-1b 유전자형이 가장 많이 검출되었고, 또한 몇 농가에서 BVDV-2a 유전자형도 검출되었다. 이들 농가에서 발생한 BVDV-1b 감염은 BVDV-2 감염과 유사한 중증의 급성 임상증상을 보여 주었다. 이 결과는 한우 송아지에서 급성이면서 치명적인 BVDV-1b 발생을 보고한다.

• Journal of Preventive Medicine and Public Health
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• 제54권5호
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• pp.370-375
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• 2021

Objectives: The number of cases of hepatitis A virus (HAV) infections has sharply increased in Korea, especially among young adults. In this study, an HAV outbreak in a facility for disabled people was investigated, and we found epidemiological differences both between 2 different generations and between generally abled and disabled groups. Methods: We analyzed the incubation period and attack rate of an HAV outbreak and investigated the prevalence of HAV antibodies among the staff and residents of a facility for the disabled. We performed a retrospective cohort study during the HAV outbreak, which lasted from February 8 to 25, 2019, including examinations of HAV antibody tests and post-exposure HAV vaccination for the staff or residents of the facility. Results: There were 9 confirmed cases in 2 staff members and 7 residents. Among 53 people (30 staff and 23 residents), except for the 9 confirmed cases and 1 staff member with a known history of HAV infection, HAV seroprevalence was seen in 16.7% of the staff under 40 years of age and 95.2% of those over 40 years of age, while the corresponding rates in the residents were 0.0% and 58.8%, respectively. Conclusions: This result implies that it is necessary to prioritize HAV vaccination for vulnerable groups and workers of residential care facilities.

• 한국병원경영학회지
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• 제22권3호
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• pp.144-156
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• 2017

Purpose: Crisis is inevitable to every organization and therefore, successful crisis management is critical to the organizations' survival and prosperity. With the understanding, this study aims to draw propositions for successful crisis management of hospitals when facing infectious disease outbreak. For the purpose, a case of a small and medium sized hospital's experience of crisis management during 2015 Middle East Respiratory Syndrome outbreak was analyzed. Methodology/Approach: The detailed internal circumstances and experiences of the hospital during the MERS outbreak were identified by in-depth interview as well as the extensive material review, and analyzed under the view of the theories of accident, error, and crisis in relation of organization management Findings: Overall, nine propositions are drawn by the phase of crisis. In pre-crisis phase, for example, 'the hospital preparedness has positive influence on the effective responding to the crisis'. In detection phase, 'the mindfulness of the hospital organizations' as well as the individuals' has positive influence on detecting the crisis signals'. In crisis phase, for example, 'improvising naturally occurs in crisis by the unknown disease, therefore, a component site supervisor coordinating such improvision is important'. Lastly, in post-crisis phase, 'successful crisis responding experience facilitates the positive hospital culture'. Practical implication: From the experience of a small and medium size hospital, it is suggested that proactive system approach oriented by safety is beneficial for effective crisis management.

• 한국환경보건학회지
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• 제33권3호
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• pp.184-189
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• 2007

Pathogenic microbial foodborne disease outbreaks (PMFBDOs) have increased in many countries, the boom in food service establishment is not matched by effective food safety and control. In this study, we investigated the current state and the epidemic aspects of FBDOs in Korea and Japan. In Korea, the average prevalence rate of foodborne disease (FBD) was 15.0 per 100,000 population and cases per outbreak of FBD was 57.0. During the same period in Japan, the prevalence rate showed an average of 24.9, and the cases per outbreak were 16. When both prevalence rate and cases per outbreak were compared, the prevalence rate in Japan was much higher than that in Korea (p<0.01). However, average cases per outbreak of FBD in Japan were much lower than those in Korea (p<0.01). In Korea, outbreaks of FBDs were more common in spring (p<0.01), while in Japan, more frequent in summer and winter (p<0.01). Outbreaks of FBD occurred largely through restaurant and school foods (32.0% and 27.5%) in Korea. In Japan, the proportion of the outbreak cases in the restaurant and home were 23.7% and 12.1%, and cases of unknown causes of FBDs were 48.2%, respectively. Bacteria were the major causes of infection in both countries. The prevalence of PMFBDOs by Salmonella spp. Vibrio parahemolyticus and Staphylococcus aureus were much higher in Korea, while those by Camphylobacter spp. and SRSV were more common in Japan. The causes by virus were more frequent in Japan (13.7%) than in Korea (7.7%). The prevalence of FBDs in Korea and Japan showed characteristic differences, especially in the PMFBDOs due to such factors as geography, climate, culture, diet and food management.

• 한국임상수의학회지
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• 제34권2호
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• pp.146-151
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• 2017

Six major outbreaks of highly pathogenic avian influenza (HPAI) occurred from 2003 to 2016 in Korea. Epidemiological investigations of each outbreak revealed that migratory birds were the primary source of the HPAI virus. During the last five years, the geographic transmission pattern of domestic HPAI seems to have extended from local to nationwide; therefore, it is necessary to identify specific locations in which poultry farms are at elevated risk for HPAI outbreak to enable targeted surveillance and other mitigation strategies. Here, a geographical information system (GIS)-based analysis was used to identify geographic areas at high risk for future HPAI incidents in Korea based on historical outbreak data collected between December 2003 and April 2016. To accomplish this, seven criteria were used to identify areas at high-risk for HPAI occurrence. The first three criteria were based on defined spatial criteria buffering of 200 bird migration sites to some defined extents and the historical incidence of HPAI outbreaks at the buffering sites. The remaining criteria were based on combined attribute information such as number of birds or farms at district levels. Based on the criteria established for this study, the most-likely areas at higher risk for HPAI outbreak were located in Chungcheong, Jeolla, Gyeonggi, and Gyeongnam provinces, which are densely populated poultry regions considered major poultry-production areas that are located along bird migration sites. The proportion of areas at risk for HPAI occurrence ranged from 4.5% to 64.9%. For the worst criteria, all nine provinces, including Jeju Island, were found to be at risk of HPAI. The results of this study indicate that the number of poultry farms at risk for HPAI outbreaks is largely underestimated by current regulatory risk assessment procedures conducted for biosecurity authorization. The HPAI risk map generated in this study will enable easy use of information by policy makers to identify surveillance zones and employ targeted surveillance to reduce the impact of HPAI transmission.