• 제목/요약/키워드: otitis externa

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개에서 Brain-stem Auditory Evoked Responses를 이용한 Deafness 진단 (Brain-stem Auditory Evoked Responses as a Diagnostic tool for Deafness in Dogs)

  • 윤영심;연성찬;권오경;남치주
    • 한국임상수의학회지
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    • 제15권2호
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    • pp.410-416
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    • 1998
  • These experiments were designed to evaluate the possibility of brain-stem auditory evoked responses(BAER) as a diagnostic tool for deafness in dogs. The BAER was recorded from three different groups of dogs; the normal dogs,'dog with otitis externa and dogs with unilateral destruction of cochlear. BAER of the normal dogs was consisted of distinct five peaks(I, II, III-IV, V). Furthermore, the clear shapes of waveform were observed at 85 dB. The latency of BAER was increased with reducing the intensity of sound-stimulus. The highest threshold of BAER was measured at 2 KHz with 10-30 dB. Dog with otitis externs demonstrated unclear shapes of BAER compared to the that of normal dogs. In the dogs with unilateral destruction of cochlear, the flat and indistinct waveform of BAER was recorded from the cochlear destroyed ear while that of BAER from normal side of ears did not show any differences from the normal BAER. These results indicate that the BAER can be clinically used in order to diagnose the deafness in dogs.

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정상개와 Malassezia 외이염을 가진 개에 있어서 Malassezia pachydermatis 추출물의 즉시형 과민반응 (Type-I Hypersensitivity to Malassezia pachydermatis Extracts in Healthy Dogs and Dogs with Malasseza Otitis Externa)

  • 김영섭;이근우;오태호
    • 한국임상수의학회지
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    • 제24권2호
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    • pp.88-93
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    • 2007
  • Malassezia pachydermatis 추출물의 피내접종시 과민반응을 알아보고자 본 실험을 수행하였다. 정상적인 개와 M. pachydermatis 외이염에 이환된 개를 대상으로 M. pachydermatis 추출물의 피내접종을 실시하였다. 전기영동을 통해 M. pachydermatis 분자량 조사를 통해 $43{\sim}63kDa$을 포함하고 있는 추출물을 사용하였다. Malassezia 외이염에 감염된 군에서의 평균 팽진의 직경은 20, 2, 0.2, and $0.02{\mu}g/ml$을 피내로 접종했을 때, 각각 $13.36{\pm}0.67,\;5.33{\pm}0.67,\;5.47{\pm}0.82$$5.07{\pm}0.64$을 나타내었으며, 팽진의 두께는 각각 20, 2, 0.2, and $0.02{\mu}g/ml$에서 $6.44{\pm}0.40,\;3.86{\pm}0.35,\;2.64{\pm}0.36$$2.60{\pm}0.44$를 나타내었다. 통계학적으로 건강한 군과 외이염에 이환된 군에 있어서 유의한 차이가 인정되었다. (p<0.01). 더구나$20{\mu}g/ml$ 을 주입한 군에서 이 차이는 더욱 두드러져 농도 의존성을 나타내었다. 따라서 M. pachydermatis 유래 항원을 개의 피내에 접종했을 때, 즉시 팽진반응을 유발한다는 것이 확인되었으며 효모균에 대한 과민증은 즉시형 피부과민반응을 보이는 개, 특히 Malassezia otitis에 감염된 개에서 임상증상의 발현에 관여하는 것으로 사료된다. 또한 2, 0.2, $0.02{\mu}g/ml$의 농도에서는 큰 차이를 보이지 않는 것으로 보아 즉시형 과민반응을 나타내기 위해서는 일정한 역치가 있을 것으로 생각되며 이에 대한 추가적인 연구가 필요할 것으로 사료된다.

개 외이도에서 분리된 Malassezia pachydermatis에 대한 키토산의 항진균 효과 (Antifungal Effect of Chitosan against Malassezia pachydermatis Isolated from the Dog with Otitis Externa)

  • 오현호;김영인;서정아;최성원;배슬기;오태호
    • 한국임상수의학회지
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    • 제29권4호
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    • pp.323-327
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    • 2012
  • The effect of pH of chitosan solution (w/v) on antifungal activity against Malassezia pachydermatis isolated from a dog with otitis externa was evaluated. This study was investigated to find out the optimal pH of chitosan solution that could be able to eliminate yeast cells. For comparison of antifungal activity of chitosan solution 2% chlorhexidine that have been already proved the antifungal effect against M. pachydermatis was used as positive control. The chitosan solution at different pH (2.5, 3.0, 3.5, 4.0, 4.5, 5.0) were involved this experiment. The chitosan solutions at each pH could eliminate a number of yeast cells when they were compared to other antifungal agents. In chitosan solution's antifungal effect of varying degrees according to the pH M. pachydermatis was inhibited at pH of < 5.0. Especially it has been proved an effective antifungal effect at pH 3.5. Therefore, the pH of chitosan solution had a effect on antifungal activity and the optimal pH was 3.5 in vitro. The possibility of topical therapy with acidific solution of chitosan has a potential in skin infection against M. pachydermatis.

Antibiotic Resistance Profiles of Staphylococcus pseudintermedius Isolates from Canine Patients in Korea

  • Yoon, Jang-Won;Lee, Ki-Jong;Lee, So-Young;Chae, Min-Joo;Park, Jae-Keun;Yoo, Jong-Hyun;Park, Hee-Myung
    • Journal of Microbiology and Biotechnology
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    • 제20권12호
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    • pp.1764-1768
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    • 2010
  • In this study, the prevalence of antibiotic resistance was examined among 74 Staphylococcus pseudintermedius strains recently isolated from clinical cases of canine pyoderma and otitis externa at the veterinary teaching hospital at Konkuk University, Korea. Bacterial resistance to the nine commonly used antibiotics was evaluated by a standard disk diffusion technique based on the guidelines of the Clinical and Laboratory Standards Institute. The results demonstrated that most S. pseudintermedius isolates were resistant to penicillin (95.9%) or tetracycline (91.9%), but highly susceptible to amoxicillin/clavulanic acid (90.5%). Among the 74 isolates, 13 mecA-positive and methicillin-resistant S. pseudintermedius (MRSP) strains were identified, displaying a high level of resistance (84.6-100%) to each of the individual antibiotics evaluated, with the exception of amoxicillin/clavulanic acid (46.2% resistance). Notably, all of the MRSP isolates exhibited simultaneous resistance to four or more different antibiotics, indicating that they are multiple drug resistant (MDR) strains. Taken together, these results imply that more careful selection or prescription of antibiotics for canine pyoderma and otitis externa should be required for reducing the emergence and/or spread of MDR strains, especially MDR-MRSP isolates, in veterinary pet clinics in Korea.

말티즈견에서의 귀지선암종 1례 (Ceruminous Gland Adenocarcinoma in a Maltese Dog)

  • 안세준;안지영;임수지;정성목;박성준;조성환;최호정;이영원
    • 한국임상수의학회지
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    • 제26권5호
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    • pp.499-503
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    • 2009
  • A 12-year-old, female, Maltese dog was presented with otic signs, such as pruritus and malordorous discharge. Medical treatment of otitis externa had been carried out for several months at primary animal hospital. Radiography, ultrasonography (US), computed tomography (CT), fine needle aspiration (FNA), and histopathological examination were performed for the diagnosis of ceruminous gland adenocarcinoma. Total ear canal ablation and lateral bulla osteotomy were performed for excision of the tumor. Facial nerve paralysis developed after surgery is getting better through the acupuncture therapy.

Per-Endoscopic Trans-Tympanic Traction Treatment of an Aural Inflammatory Polyp in a Cat

  • Park, Won-Keun;Song, Doo-Won;Shin, Dong-Hoon;Kim, So-Yeon;Lee, Ga-Won;Kang, Dong-Jae;Ro, Woong-Bin;Cho, Jong-Mun;Park, Hee-Myung
    • 한국임상수의학회지
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    • 제38권3호
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    • pp.147-151
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    • 2021
  • A 5-year-old castrated male Maine Coon cat presented with chronic otitis on the right ear. The clinical signs, scratching and head shaking, were recurrent despite symptomatic treatment, including antibiotics and antifungal agents. Video otoscopic examination and computed tomography (CT) examination revealed a polyp in the right ear canal. The polyp was removed via per-endoscopic trans-tympanic traction (PTT) with a grasping forceps. After treatment, Horner's syndrome occurred in the right eye but spontaneously resolved a week later. The mass was diagnosed as inflammatory polyp with a fibrovascular stroma containing plasma cells, lymphocytes, and neutrophils. All clinical signs were improved, and no recurrence was observed after 3 weeks of follow-up. This case report demonstrates that CT scan is effective in identifying the margin of polyp and PTT technique is non-invasive method for treating inflammatory polyp in cats without severe complications.

개에서 만성외이염과 중이염에 대한 전이도 적출술과 외측 고포절골술: 수술 후 회복과정과 장기간 예후 (Total Ear Canal Ablation and Lateral Bulla Osteotomy for Chronic Otitis Externa and Media in Dogs: Postoperative Recovery and Long-Term Follow-up)

  • Kim, Joon-Young;Jeong, Soon-Wuk;Jeong, Man-Bok;Han, Hyun-Jung;Kim, Je-Sun
    • 한국임상수의학회지
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    • 제20권1호
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    • pp.26-32
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    • 2003
  • 전이도적출술 및 외측고포절골술 (total ear canal ablation combined with lateral bulla osteotomy, TECA-LBO)을 행한 10개의 (6마리의 개) 임상결과를 수술 후 회목과정과 장기간 예후를 통해서 평가하였다. 모든 개들은 아래의 다섯가지 소견을 보일 때 TECA-LBO를 실시하였다. 첫째, 적어도 2개월 이상 약물적인 치료가 더 이상 임상증상을 호전시키지 못하는 경우, 둘째, 고막이 완전히 사라진 경우, 셋째, 고포의 방사선밀도가 증가된 경우, 넷째, petrous temporal bone에 경화가 일어난 경우, 다섯째, 이도의 석회화가 진행된 경우. 수술 후 회복경과는 입원 14일 동안, 퇴원 후 7.5개월에 평가하였다. 수술 후 14일째 만성외이염 및 중이염의 증상인 귀를 긁는 것, 통증, 그리고 귀의 경화는 사라졌다. 그리고 이때 수술부위의 종창, 발적, 머리를 기울이는 증상 그리고 Penrose에 의한 삼출물은 모두 사라졌다. 눈을 깜박이지 못하는 것은 4예에서 발생하였고, 이것은 수술 후 14일째 사라졌다. 하지만 한 경우에는 3개월 뒤에 사라졌다. 모든 개들은 수술 후 14일째 퇴원하였다. 퇴원 후 3.5개월에서 6.5개월 사이에 para-aural abscessation이 모든 코커 스파니엘 종에서 발생하여 VBO을 통해 완치시켰다. TECA-LBO를 행하고 para-aural abscessation이 생기지 않은 개들에서는 수술 후 7.5개월 후 귀를 긁는 것, 통증, 귀의 경화가 더 이상 발견되지 않았고, 듣는 능력도 향상되었다. 또한 TECA-LBO를 행하고 para-aural abscessation이 생긴 개들에서는 VBO를 행하고 7.5개월 후 귀를 긁는 것, 통증, 귀의 경화가 더 이상 발견되지 않았고, 듣는 능력도 향상되었다. 결론적으로 전이도적출술 및 외측고포절골술은 적용한 후 약 2주 정도의 치료 경과를 보였고 치료 후 코커 스파니엘종을 제외하고는 별다른 합병증 없이 좋은 회복을 보였다. 그리고 수술 후 눈을 깜박이지 못하는 것은 수술 후 약 2주안에 자연적으로 사라졌다. 그리고, para-aural abscessation은 수술 후 4개월에서 7개월 사이에 발생하므로 follow-up 은 8개월까지 이루어져야 한다.

Ceruminous Gland Adenocarcinoma in a Maltese Dog

  • O, I-Se;Lim, Soo-Ji;Park, Seong-Jun;Jeong, Seong-Mok;Lee, Jae-Yeon;Cho, Sung-Whan;Choi, Ho-Jung;Lee, Young-Won
    • 한국임상수의학회:학술대회논문집
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    • 한국임상수의학회 2008년도 춘계학술대회
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    • pp.108-108
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    • 2008
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