• 제목/요약/키워드: osteoporosis

검색결과 1,471건 처리시간 0.022초

원주농촌코호트에서 사상체질별 심혈관위험인자와 골다공증의 관계 (Relationship between Osteoporosis and Cardiovascular Risk Factors according to Sasang Constitution in Rural Wonju Cohort)

  • 송학수;최재완;유준상;박종구
    • 사상체질의학회지
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    • 제25권2호
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    • pp.81-97
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    • 2013
  • Objectives The purpose of this study was to investigate the relationship between osteoporosis and cardiovascular risk factors according to Sasang constitution. Methods A total of 1773 participants, over 40 years old, were examined as part of a community-based cohort in Wonju city in Gangwon province of South Korea, from June 2006 to August 2009. We measured bone mineral density by Achilles ultrasonometer, serum levels of lipids, fasting blood sugar, insulin and other cardiovascular risk factors like blood pressure and waist circumference. Constitution was verified by a Sasang constitution specialist using the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Results The prevalence rate was 11.2% in total participants, and 10.6% in Soyangin, 10.4% in Taeeumin and 13.9% in Soeumin. In general characteristics, educational and economic property and exercise were concerned with osteoporosis. Systolic blood pressure, pulse rate and total cholesterol were significantly high in osteoporosis group. Age and menopause were the key risk factors for osteoporosis. There was a significantly high prevalence in Soeumin for osteoporosis in men alone. Low physical activity was a major risk factor for osteoporosis. Waist circumference and hip circumference had significantly high odds ratio and weight had significantly low odds ratio. By Sasang constitution, Soyangin has the negative correlation with free fatty acid, Taeeumin has the negative correlation with waist circumference, pulse rate, systolic blood pressure, total cholesterol and low density lipoprotein and Soeumin has the positive correlation with body fat amount. Conclusions Regimens on osteoporosis should be considered according to Sasang constitution. Cardiovascular diseases should be considered according to Sasang constitution. Soeumin should be cautious of osteoporosis and gain weights and reasonable amount of fat food. Soyangin had better do exercise lower body and eat little food containing triglyceride. Taeeumin had better lose weights and eat little cholesterol food.

골다공증(骨多孔症)의 한의학적(韓醫學的) 인식(認識)과 침구치료(鍼灸治療)의 문헌연구(文獻硏究) (The literatural study on the oriental cognizance and acupuncture-moxibustion therapy of osteoporosis)

  • 김동수;김영일
    • 혜화의학회지
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    • 제18권1호
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    • pp.9-18
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    • 2009
  • Objectives and Methods: The treatments of osteoporosis in occidental medicine are need complementations for reason of low-continuation and adverse-drug-reaction. So we would have literature centered consideration both oriental medical cognition and acupuncture-moxibustion therapy in osteoporosis. Results: 1. Deficiency of bone marrow caused by heat in the kidney and deficiency of kidney Gi, is causative of osteoporosis in pathology in oriental medicine. 2. Bone flaccidity and bone impediment are similar with osteoporosis. Withered bone comes under pathogenesis of bone flaccidity. And heavy debilitating disease of the bone is exacerbation of bone impediment. 3. In acupuncture-moxibustion therapy of osteoporosis, Bladder Meridian of Foot Taeyang, Kidney Meridian of Foot Soeum, Gallbladder Meridian of Foot Soyang, Lung Meridian of Hand Taeeum, Large Intestine Meridian of Hand Yangmyeong, Spleen Meridian of Foot Taeeum, Conception Channel, Stomach Meridian of Foot Yangmyeong, and Heart Meridian of Hand Soeum are used much in the order named. 4. In acupuncture-moxibustion therapy of osteoporosis, Hyeonjong(GB39, 7times), Daejeo(BL11, 3times), Sanggwan(GB3, 2times), Sinsu(BL23, 2times), Gyeoksu(BL17, 2times), Honmun(BL47, 2times), Buryu(KI7, 2times), Taebaek(SP3, 2times), Sanggu(SP5, 2times), Sangnyeom(LI9, 2times) are used much in the order named. Conclusions: In treatment of osteoporosis, we could make full use of acupuncture-moxibustion therapy. And we need active and persistent study about osteoporosis.

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Effect of Childbirth Age on Bone Mineral Density in Postmenopausal Women

  • We, Ji Sun;Han, Kyungdo;Kwon, Hyuk-Sang;Kil, Kicheol
    • Journal of Korean Medical Science
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    • 제33권48호
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    • pp.311.1-311.10
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    • 2018
  • Background: In postmenopausal women, there is rapid bone loss due to estrogen depletion. In women, reproductive factors such as age at menarche, breastfeeding, and parity are considered risk factors of osteoporosis. Many reports suggest that obesity is associated with a reduced risk of osteoporosis. This nationwide, population-based study aims to identify the association between maternal age and osteoporosis risk in postmenopausal women of different obesity classifications. Methods: We assessed data from the Korean National Health and Nutrition Examination Survey 2010-2012. The study included 1,328 postmenopausal women, after excluding women with missing data for reproductive history among 4,546 postmenopausal women in the survey. Multivariate regression was used to identify the association between childbirth age and postmenopausal bone mineral density after adjustments for confounding factors. Results: The prevalence of postmenopausal osteoporosis was 35.24% (n = 468). After dividing the subjects into obese and non-obese groups based on body mass index (BMI) and waist circumference, there were significant differences between non-osteoporosis and osteoporosis groups with regard to age at first childbirth, age at last childbirth, and parity in the BMI-based general obesity group. The prevalence of osteoporosis was highest in women older than 35 years old at last childbirth. The prevalence of osteoporosis was also greater in women with parity ${\geq}4$ compared to those with lower parity levels. Conclusion: Postmenopausal women of older age at last childbirth and higher parity were at increased risk of osteoporosis in the BMI-based non-general obesity group.

고령 장애인의 골다공증 유무에 따른 일상생활수행능력과 삶의 질 비교 (Comparison of ADL and QoL for the Osteoporosis and Non-osteoporosis in elderly people with disabilities)

  • 김예순;남영희
    • 한국학교ㆍ지역보건교육학회지
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    • 제22권1호
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    • pp.1-9
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    • 2021
  • Objective: This study examines the prevalence of osteoporosis, and compares with activity of daily living(ADL), instrumental activity of daily living(IADL) and health-related quality of life(QoL) among the elderly people with disabilities. Methods: This study analyzed the data of 3,113 persons with disabilities over 65 years of age who responded to the questionnaire using data from the National Survey of People with Disabilities in 2017 on the people with disabilities (PWD). Descriptive statistics, X2-test, and independent sample t-test were conducted using the SPSS win 21.0 program. Results: The prevalence of osteoporosis in the elderly PWD was 18.7%. There were significant differences in sex, age, type of disability, and disability severity according to the presence or absence of osteoporosis (p<0.05). Walking and Transfer of ADL were related to osteoporosis in elderly PWD. Financial management and Transportation use of IADL were related to osteoporosis (p<0.05). The PWD with osteoporosis were analyzed to have lower health-related quality of life compared to the disabled elderly without osteoporosis (p<0.05). Conclusion: Based on the results of this study, a strategy for developing a program for managing osteoporosis. Strengthening health management in the elderly PWD is required.

Osteoporosis: New Biomedical Engineering Aspects

  • Singh, Kanika;Lee, Sung-Hak;Kim, Kyung-Chun
    • Journal of Mechanical Science and Technology
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    • 제20권12호
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    • pp.2265-2283
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    • 2006
  • There is tremendous interest of research which surrounds the concept of 'osteoporosis,' as shown by the intense and growing research activity in the field. The urgency to advance knowledge in this area is motivated by the need to understand not only the causes, diagnosis and treatment but also need for early identification or detection of this silent disease. Despite the various researches work is going on, important issues remain unresolved. In this paper, Osteoporosis has also been discussed with respect to biological, engineering, biochemical and physical aspects. The diagnostic and therapeutic techniques have been described for osteoporosis, for better health care. The novelty of the review paper lies in clarifying several myths, explaining the disease in details with biomedical engineering aspects and focuses on the several detection techniques, providing a new direction for early diagnosis of this deadly disease and gives new directions for the POCT device for Osteoporosis.

골 다공증의 최신 약물 치료 (Recent Advances in the Drug Therapy of Osteoporosis)

  • 이형우
    • Journal of Yeungnam Medical Science
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    • 제16권2호
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    • pp.155-168
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    • 1999
  • Osteoporosis is one of the most important public health problems facing the aging population. Drug therapy for osteoporosis can be divided operationally into two main categories: drugs that inhibit bone resorption, and thus reduce bone turnover, and those that stimulate bone formation, exerting an anabolic effect. Antiresorptive agents such as estrogens, calcitonin, and bisphosphonates are most effective in the prevention of osteoporosis. Formation-stimulating agents such as sodium fluoride or monofluorophosphate, parathyroid hormone fragments, and anabolic steroids are of potential value in the treatment of established osteoporosis, where bone mass is already low and benefit from antiresorptive drugs is likely to be small Recently, raloxifene, a selective estrogen receptor modulator, has become available in various countries for clinical use in the treatment of involutional osteoporsis. This paper will review the use of these drugs in postmenopausal woman.

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Biological characteristics of osteoporosis drugs: the effect of osteoblast-osteoclast coupling

  • Kim, Sung-Jin;Moon, Seok Jun;Seo, Jeong Taeg
    • International Journal of Oral Biology
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    • 제44권1호
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    • pp.1-7
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    • 2019
  • Osteoporosis is a common disease characterized by bone mass reduction, leading to an increased risk of bone fracture, and it is caused by an imbalance of osteoblastic bone formation and osteoclastic bone resorption. Current osteoporosis drugs aim to reduce the risk of bone fracture, either by increasing osteoblastic bone formation or decreasing osteoclastic bone resorption. However, osteoblasts and osteoclasts are closely coupled, such that any reagent altering the differentiation or activity of one eventually affects the other. This tight coupling between osteoblasts and osteoclasts not only limits the therapeutic efficacy but also threatens the safety of osteoporosis drugs. This review will discuss the biological mechanisms of action of currently approved medications for osteoporosis treatment, focusing on the osteoblast-osteoclast coupling.

세포교정영양요법(OCNT)을 이용한 골다공증 환자 사례 연구 (A Case Study on an Osteoporosis Patient Using Ortho-Cellular Nutrition Therapy (OCNT))

  • 차명진
    • 셀메드
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    • 제13권12호
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    • pp.47.1-47.8
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    • 2023
  • Objective: A case report on the improvement of symptoms in an osteoporosis patient using ortho-cellular nutrition therapy Methods: Currently a 70 years old Korean woman was diagnosed with osteoporosis in her late 50s around 2010 and continued to receive injection treatments once every three months. Her T-score did not improve, and fractures continued to occur in the ankles, wrists, shoulders, ribs, etc., even from light impacts. Results: The patient underwent an osteoporosis test in February 2019, which resulted in an average T-score of -2.5 or less, equivalent to being diagnosed with osteoporosis. OCNT has been performed since May 2019 (late 60s), and in the test received in April 2020, the T-score value improved to over -2.5 and was determined normal at the hospital. Since then, OCNT continued without any further injection treatments. Unlike before, even when she fell hard, she only suffered bruises without fractures, and no additional fractures have occurred. Conclusion: OCNT may help patients with similar problems relieve symptoms and recover.

직장 근로자의 골다공증 유병실태와 관련요인 연구 (A Study of Prevalence and Related Risk Factors of Osteoporosis for Employees)

  • 홍순안;유시영
    • 한국전자통신학회논문지
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    • 제8권4호
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    • pp.631-637
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    • 2013
  • 본 논문은 G광역시 H병원에서 S전자 근로자를 대상으로 골다공증 검사를 실시함으로 근로자들의 골다공증 유병율과 관련 요인을 파악하여 직원들의 건강을 증진시킬 수 있는 보건교육 프로그램의 기초자료로 제시하고자 연구되었다. 또한 가족과 집을 떠나 원거리에 근무하는 직장 근로자들에 있어 골다공증 실태를 파악하여 골다공증과 관련한 자료를 제시하고자 하였다. 연구결과 골다공증의 발생원인으로는 성별, 직급, 체중 등이 관련 있었으며, 실험에 참여한 대부분의 대상자가 골다공증이 있거나, 관리대상으로 볼 때 기업체 내의 골다공증에 대한 조직적인 예방과 집중적인 관리가 필요함을 알 수 있었다. 골다공증은 직장 근로자들에게 있어 흡연, 음주, 운동부족, 카페인과 같은 생활 습관에 대한 보다 더 심층적인 연구가 필요함을 절감했다.

High dairy products intake reduces osteoporosis risk in Korean postmenopausal women: A 4 year follow-up study

  • Park, Seon-Joo;Jung, Ji Hye;Ki, Myung-Sunny;Lee, Hae-Jeung
    • Nutrition Research and Practice
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    • 제12권5호
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    • pp.436-442
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    • 2018
  • BACKGROUND/OBJECTIVES: The aim of this study was to identify the effect of dairy products, milk and yogurt on osteoporosis incidence among Korean postmenopausal women using prospective cohort data. MATERIALS/METHODS: Between 2001 and 2003, 10,038 participants were recruited in rural and urban areas for a baseline examination of a community-based cohort study. Of those, 1,573 postmenopausal women (aged 40-69 years at baseline) were eligible for the present study. Intakes of dairy products, milk, and yogurt were assessed using a validated semi-quantitative food frequency questionnaire. The speed of sound at the radius and tibia were measured using a quantitative ultrasound device and osteoporosis was defined based on the WHO criteria (T-score ${\leq}-2.5$). RESULTS: During the 4-years follow-up study, the cumulative incidence of osteoporosis was 18.4% (273 cases) in the radius and 33.6% (407 cases) in the tibia. The subjects with higher frequency of dairy product consumption showed a decreased risk of radius osteoporosis after adjusting for potential confounders [hazard ratio (HR) = 0.51, 95% confidence interval (CI): 0.33-0.80 for >1 time/day vs. non consumer; P for trend = 0.0027]. Similarly, high frequency of milk and yogurt consumption had a protective effect on radius osteoporosis risk [milk: HR = 0.60, 95% CI: 0.42-0.87 for > 5-6 times/week vs. non consumer (P for trend = 0.0130), yogurt: HR = 0.51, 95% CI: 0.30-0.85 for > 5-6 times/week vs. non consumer (P for trend = 0.0167)]. However, high dairy products consumption was not related with tibia osteoporosis. CONCLUSIONS: This study suggests that daily intake of dairy products could potentially reduce radius osteoporosis incidence among Korean postmenopausal women.