• Title/Summary/Keyword: orthopedic surgery

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Neurotropin protects rotator cuff tendon cells from lidocaine-induced cell death

  • Abe, Ryunosuke;Ohzono, Hiroki;Gotoh, Masafumi;Nakamura, Yosuke;Honda, Hirokazu;Nakamura, Hidehiro;Kume, Shinichiro;Okawa, Takahiro;Shiba, Naoto
    • Clinics in Shoulder and Elbow
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    • v.24 no.4
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    • pp.224-230
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    • 2021
  • Background: Local anesthetics often are used in rotator cuff tears as therapeutic tools, although some cases have reported that they have detrimental effects. Neurotropin (NTP) is used widely in Japan as a treatment for various chronic pain conditions and is shown to have protective effects on cartilage and nerve cells. In this study, we investigated the protective effect of NTP against lidocaine-induced cytotoxicity. Methods: Tenocytes from rotator cuff tendons were incubated with lidocaine, NTP, lidocaine with NTP, and a control medium. Cell viability was evaluated using the WST-8 assay. Cell apoptosis was detected via annexin V staining using flow cytometry. The expression of BCL-2 and cytochrome c, which are involved in the intrinsic mitochondrial pathway of apoptosis, was evaluated via Western blotting and immunohistochemical staining. Results: In the cell viability assay, lidocaine decreased cell viability in a dose-dependent manner, and NTP did not affect cell viability. Moreover, NTP significantly inhibited the cytotoxic effect of lidocaine. The flow cytometry analysis showed that lidocaine significantly induced apoptosis in tenocytes, and NTP considerably inhibited this lidocaine-induced apoptosis. Western blotting experiments showed that lidocaine decreased the protein expression of BCL-2, and that NTP conserved the expression of BCL-2, even when used with lidocaine. Immunohistochemical staining for cytochrome c showed that 0.1% lidocaine increased cytochrome c-positive cells, and NTP suppressed lidocaine-induced cytochrome c expression. Conclusions: NTP suppresses lidocaine-induced apoptosis of tenocytes by inhibiting the mitochondrial apoptotic pathway. Intra-articular/bursal injection of NTP with lidocaine could protect tenocytes in rotator cuff tendons against lidocaine-induced apoptosis.

Internet search analytics for shoulder arthroplasty: what questions are patients asking?

  • Johnathon R. McCormick;Matthew C. Kruchten;Nabil Mehta;Dhanur Damodar;Nolan S. Horner;Kyle D. Carey;Gregory P. Nicholson;Nikhil N. Verma;Grant E. Garrigues
    • Clinics in Shoulder and Elbow
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    • v.26 no.1
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    • pp.55-63
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    • 2023
  • Background: Common questions about shoulder arthroplasty (SA) searched online by patients and the quality of this content are unknown. The purpose of this study is to uncover questions SA patients search online and determine types and quality of webpages encountered. Methods: The "People also ask" section of Google Search was queried to return 900 questions and associated webpages for general, anatomic, and reverse SA. Questions and webpages were categorized using the Rothwell classification of questions and assessed for quality using the Journal of the American Medical Association (JAMA) benchmark criteria. Results: According to Rothwell classification, the composition of questions was fact (54.0%), value (24.7%), and policy (21.3%). The most common webpage categories were medical practice (24.6%), academic (23.2%), and medical information sites (14.4%). Journal articles represented 8.9% of results. The average JAMA score for all webpages was 1.69. Journals had the highest average JAMA score (3.91), while medical practice sites had the lowest (0.89). The most common question was, "How long does it take to recover from shoulder replacement?" Conclusions: The most common questions SA patients ask online involve specific postoperative activities and the timeline of recovery. Most information is from low-quality, non-peer-reviewed websites, highlighting the need for improvement in online resources. By understanding the questions patients are asking online, surgeons can tailor preoperative education to common patient concerns and improve postoperative outcomes. Level of evidence: IV.

Effect of suprascapular nerve injury on muscle and regenerated enthesis in a rat rotator cuff tear model

  • Kenichiro Eshima;Hiroki Ohzono;Masafumi Gotoh;Hisao Shimokobe;Koji Tanaka;Hidehiro Nakamura;Tomonoshin Kanazawa;Takahiro Okawa;Naoto Shiba
    • Clinics in Shoulder and Elbow
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    • v.26 no.2
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    • pp.131-139
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    • 2023
  • Background: Massive rotator cuff tears (RCTs) are complicated by muscle atrophy, fibrosis, and intramuscular fatty degeneration, which are associated with postoperative tendon-to-bone healing failure and poor clinical outcomes. We evaluated muscle and enthesis changes in large tears with or without suprascapular nerve (SN) injury in a rat model. Methods: Sixty-two adult Sprague-Dawley rats were divided into SN injury (+) and SN injury (-) groups (n=31 each), comprising tendon (supraspinatus [SSP]/infraspinatus [ISP]) and nerve resection and tendon resection only cases, respectively. Muscle weight measurement, histological evaluation, and biomechanical testing were performed 4, 8, and 12 weeks postoperatively. Ultrastructural analysis with block face imaging was performed 8 weeks postoperatively. Results: SSP/ISP muscles in the SN injury (+) group appeared atrophic, with increased fatty tissue and decreased muscle weight, compared to those in the control and SN injury (-) groups. Immunoreactivity was only positive in the SN injury (+) group. Myofibril arrangement irregularity and mitochondrial swelling severity, along with number of fatty cells, were higher in the SN injury (+) group than in the SN injury (-) group. The bone-tendon junction enthesis was firm in the SN injury (-) group; this was atrophic and thinner in the SN injury (+) group, with decreased cell density and immature fibrocartilage. Mechanically, the tendon-bone insertion was significantly weaker in the SN injury (+) group than in the control and SN injury (+) groups. Conclusions: In clinical settings, SN injury may cause severe fatty changes and inhibition of postoperative tendon healing in large RCTs. Level of evidence: Level Basic research, controlled laboratory study.

Analysis of the Nursing Interventions performed by orthopedic surgery care unit using NIC (NIC 간호중재 분류체계를 이용한 간호중재분석;정형외과 간호단위를 중심으로)

  • Kwon, Mi-Suk;Park, Kyung-Sook
    • Journal of Korean Academy of Nursing Administration
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    • v.8 no.4
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    • pp.655-667
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    • 2002
  • Purpose : This study analysis of nursing interventions and core nursing interventions performed orthopedic surgery care unit. Method : The data were collected from 55 nurses of 4 general hospital from July. 10, 2002 to Aug. 30, 2002. The instrument for this study was the Korean translation of 486 nursing intervention classifications developed by McColskey & Bulechek in 2000. In the 486 nursing interventions 350 nursing interventions were selected 8 among the 10 more than 5 years working group in orthopedic surgery care unit. Self frequency checking performed by 350 nursing interventions were used secondary questionnaire In the orthopedic surgery care unit nurses. Results : 1. The most frequently used nursing interventions domains were "Physiological : basic" and then "Physiological: complex", "Health system" "Behavior", "Family", "Safety". 2. Orthopedic surgery care unit core nursing interventions were performed several times a day by 50% or more of orthopedic surgery care unit and this result were 4 of domain, 11 of class, 26 core nursing interventions. This core nursing interventions were 5 of "Physiological : basic", 17 of "Physiological: complex", 1 of "Safety", 3 of "Health system" and have no "Behavior", "Family". Conclusion : This study analyzed nursing intervention of orthopedics and reestablished nursing intervention concept and I hope this study will be helpful for the nurse to be a professional by applying this to actual clinic, for development in qualified nursing and for establishment nursing information system.

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Extensor Hallucis Longus Tendon Rupture in TaeKwonDo Players: Two Case Report (태권도 선수에서 발생한 장 족무지 신전건의 파열: 2예 보고)

  • Lee, Kyung-Tai;Kim, Jin-Su;Young, Ki-Won;Kim, J-Young;Choi, Jae-Hyuck;Park, Hyun-Kyoo;Kim, Byung-Kwan
    • Journal of Korean Foot and Ankle Society
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    • v.10 no.1
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    • pp.101-104
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    • 2006
  • Occasionally, extensor hallucis longus tendon (EHL) ruptures becames open by laceration and spontaneous rupture of EHL that has previous story of diabetes mellitus, steroid injection, systemic steroid administration, operation and rheumatoid arthritis. But, closed traumatic EHL ruptures are reported rarely. Especially, we diagnosed the closed EHL ruptures in TaeKwonDo players. We reported the 2 patients, differently treated end to end anastomosis and EHL transfer, had the course and treatment methods. Be care the prognosis can be altered according to the treatment time and method.

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Lateral Epicondylitis: Current Concept

  • Jeon, In-Ho;Kekatpure, Aashay Laxmikant;Sun, Ji-Ho;Shim, Kyeong-Bo;Choi, Sung-Hoon;Lim, Sung-Joon;Chun, Jae-Myeung
    • Clinics in Shoulder and Elbow
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    • v.17 no.3
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    • pp.138-144
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    • 2014
  • Lateral epicondylitis is one of the most common causes of elbow pain and has been known to be caused by degeneration of the extensor carpi radialis brevis (ECRB). Nonoperative treatment should be tried first in all patients, because it has been deemed highly successful; however only few prospective studies suggest that symptoms frequently was completely resolved. Operative treatment is indicated for recalcitrant pain after failed conservative treatment, which involves excision of the pathologic portion of the ECRB and results in a high degree of subjective relief and functional restoration. We will review the pathology of the lateral epicondylitis and operative and nonoperative treatment of lateral epicondylitis.

Reverse Superficial Sural Artery Flap for Reconstruction of Soft Tissue Defect (역혈행성 비복 동맥 피판술을 이용한 연부 조직 결손의 재건)

  • Lee, Sang-Soo;Lee, Young-Ho;Kim, Joo-Sung;Choi, Jae-Hyuck;Lee, Young-Hyun;You, Yeon-Sik;Nam, Il-Hyun
    • Journal of Korean Foot and Ankle Society
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    • v.6 no.1
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    • pp.46-53
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    • 2002
  • Purpose: We would introduce the reverse superficial sural artery flap to reconstruct soft tissue defect on lower leg, ankle, and hind-foot. Materials and Method: From October 1998 to December 2001, we reconstructed 12cases (l2patients) of soft tissue defect around the hind - foot, ankle, and distal lower extremity with the reverse sural artery flap. Results: The time for flap dissection was 28 minutes in average. The size of the flap was from $4\times3cm$ to $14\times10cm$. All flaps survived. Conclusion: The reverse superficial sural artery flap is the useful technique for the soft tissue defect in the lower leg and the foot.

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Chorpart's Dislocation: A Case Report (중족근 관절 탈구: 1예 보고)

  • Choi, Jun-Weon;Choi, Joon-Choil;Na, Hwa-Yeop;Shim, Dong-Joon;Kim, Young-Ho;Lee, Sang-Ho;Cho, Hyoung-Wook
    • Journal of Korean Foot and Ankle Society
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    • v.9 no.1
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    • pp.121-124
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    • 2005
  • The midtarsal joint which consists of the talonavicular and calcaneocuboid joints lies transversely across the medial and lateral arches of the foot. Complete dislocation of this joint unassociated with fracture is extremely rare. A 36 year-old male who was injured by motor vehicle accident came to help for his left midfoot pain and deformity. We misdiagnosed as subtalar dislocation. Closed reduction was performed. We reviewed initial and post-reduction X-rays, and then we diagnosed as Chopart's dislocation. CT scan was taken; it showed fracture of the anterior process of the calcaneous.

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Painful Osteochondroma of the Hallucal Sesamoid: A Case Report (통증을 동반한 족무지 종자골의 골연골종: 증례 보고)

  • Kim, Dae Geun;Ahn, Gil Yeong;Nam, Il Hyun;Lee, Yeong Hyeon;Lee, Tae Hun;Lee, Yong Sik;Lee, Dong Hyun
    • Journal of Korean Foot and Ankle Society
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    • v.20 no.3
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    • pp.140-144
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    • 2016
  • Osteochondroma is one of the most common bone tumors. It can occur anywhere, although it is most frequent mainly around the metaphysis of long bones. Prediction sites are distal femur, proximal humerus, proximal tibia, and so on. However, osteochondroma in sesamoid is very rare. Herein, we report a case of a 56-year-old woman with symptomatic extra-articular osteochondroma in hallucal sesamoid with a brief literature review.

Early Diagnosis of Acute Hematogenous Osteomyelitis Using the Ultrasonography in a Child: A Case Report (초음파를 이용한 소아 급성 혈행성 골수염의 조기 진단: 증례보고)

  • Min, Kyoung-Dae;Ahn, Joong-Hyun;Cho, Woo-In;Hwang, Seok-Ha;Cho, Sang-Hyuck;Song, Sang-Hun;Lee, Byung-Ill
    • The Journal of Korean Orthopaedic Ultrasound Society
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    • v.6 no.2
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    • pp.76-80
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    • 2013
  • It is very important to make an early diagnosis of acute hematogenous osteomyelitis in children to avoid various complications. We report a case of a five-year-old patient with tibial subperiosteal abscess, who was diagnosed using ultrasonography and treated at the early point of the disease.

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