• Plant Resources
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• 제6권2호
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• pp.94-97
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• 2003

The objective of this study is to investigate morphological characteristics of seeds and effects of environmental factors such as light and temperature on the germination and seedling growth of Adenophora triphylla var. japonica, Codonopsis lanceolata, Platycodon glandiflorum, Which belongs to Campanulaceae and useful for on oriental medicine materials. Seed shape of Codonopsis lanceolata is Elliptic. Platycodon glandiflorum is Oblong. Color of seed coats varied from yellow to dark brown. Seed size of Adenophora triphylla var. japonica is 1.37mm in length, 0.69mm in width. One thousand-seed weight of Adenophora triphylla var. japonica is 258mg. Seed size of Codonopsis lanceolata is 4.45mm in length, 2.11mm in width. One thousand-seed weight of Codonopsis lanoceolata is 1,278mg. Seed size of Platycodon glandiflorum is 2.31mm in length, 1.10mm in width. One thousand-seed weight of Platycodon glandiflorum is 988mg. Optimum temperatures for seed germination and seedling growth range from 20 to $25^{\circ}C$.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 추계학술발표회
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• pp.348-349
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• 2011

• Preventive Nutrition and Food Science
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• 제15권3호
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• pp.189-195
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• 2010

Water extracts from 20 medicinal plants, traditionally used for postmenopausal symptoms in Korea, were examined for their vasorelaxant activity in isolated rat thoracic aorta rings precontracted with norepinephrine (NE). Among the 20 medicinal plants, Cornus officinalis (CoEx, 0.3 mg/mL), Schisandra chinensis (ScEx, 0.3 mg/mL), Erythrina variegate (EvEx, 0.3 mg/mL), and Epimedium koreanum (EkEx, 0.3 mg/mL) showed rapid relaxation of endothelium-intact aorta ($69\pm4%$, $40\pm3%$, $25\pm2%$, and $23\pm3%$ of active tone induced by NE, respectively). In contrast, the extracts of Erythrina variegata (EvEx), Angelica gigas (AgEx), Pueraria thunbergiana (PtEx), and EkEx lead to gradual (i.e., long-term) relaxation to baseline in endothelium-intact vessels. The time to complete relaxation was 20～40 min. These 6 plant extracts were selected for the investigation of possible underlying mechanisms. The CoEx-, ScEx-, or EkEx-induced rapid relaxations were virtually abolished by endothelium denudation, and were significantly inhibited by pretreatment with nitric oxide (NO) synthase inhibitor $N^G$-nitro-L-arginine (L-NNA, 10 ${\mu}M$), indicating that increased formation of NO might contribute to the endothelium-mediated relaxation. In long-term responses, the endothelium denudation did not affect PtEx-induced relaxation, whereas it delayed responses by EvEx and AgEx, and significantly inhibited the effect of EkEx. Among EvEx, AgEx, and PtEx, EvEx attenuated the $CaCl_2$-induced vasoconstriction in high-potassium depolarized medium, implying that EvEx is involved in inhibition of the extracellular calcium influx to smooth muscle through voltage dependent calcium channels. These results provide the scientific rationale for the interrelationships between the use of 20 medicinal plants and their effects on cardiovascular health in estrogen deficient conditions.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 추계국제학술대회
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• pp.80-80
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• 2020

Glycyrrhizae Radix (GR), commomly known as liquorice, is a medicinal and edible plant widely used in East Asia with its pharmacological properties. Currently, Glycyrrhiza uralensis, G. glabra and G. inflata are used for pharmaceutical purposes in Korea and then the improved Glycyrrhiza varieties, WON-GAM (WG) has been developed by Korea Rural Development Administration. To evaluate equivalence of efficacy, several comparative studies between already-registered species and new cultivars have been conducted. To evaluate equivalence of efficacy, several comparative studies between already-registered species and new cultivars have been conducted. The aim of this study was to evaluate the effect of WG on fecal microbiota in DSS-induced colitis model. Fecal microbiota was analyzed by terminal restriction fragment length polymorphism (T-RFLP). The composition of the fecal microbiota did not show a specific pattern based on experimental groups; however, a tendency toward an increase in the proportion of Lactobacillales was observed. Glycyrrhiza varieties could change composition of fecal microbiota in DSS-induced colitis model. This work was carried out with the support of "Cooperative Research Program for Agriculture Science and Technology Development (Project No. PJ014246022020)" Rural Development Administration.

• 한국약용작물학회지
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• 제10권5호
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• pp.419-422
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• 2002

참당귀 신품종 "안풍"은 작물시험장에서 지역수집종을 개체 및 집단선발하여 육성한 품종이다. 1999년부터 2001년까지 수원, 평창, 봉화 3지역에서 지역적응시험을 실시한 결과 저추대 고품질 다수성으로 인정되어 2001년 농촌진흥청 농작물직무육성 신품종선정심의위원회에서 신규품종으로 결정되어 품종보호출원을 하였다. 안풍의 주요 특성은 다음과 같다. 1. 엽색은 녹색이고 줄기색은 녹색에 자색을 띠며 꽃색은 적자색이고 종피색은 담갈색이다. 뿌리의 표피는 황갈색이고 육질은 백색이다. 2. 초장은 만추당귀 보다 길며 엽수는 비슷하였으나 생육기간중 지상부 생육은 만추당귀에 비하여 양호하였다. 뿌리는 만추당귀에 비하여 근장이 길고 근경이 굵으며 지근수가 많아 주당 건근중이 무거웠다. 3. 점무늬병은 만추당귀와 비슷하였으나 뿌리썩음병은 다소 적었다. 응애는 만추당귀와 비슷하였다. 4. 온상육묘이식 재배시 1년차에 안풍의 추대율은 0.6%로 만추당귀 0.3%보다는 다소 높았으나 진부재래 49.3%보다 낮았다. 노지육묘이식 재배시 2년차에 추대 및 개화되는 정도는 $0{\sim}15%$정도이다. 5. 3개지역 3년간 안풍의 평균수량은 3,630 kg/ha로 만추당귀 3,270 kg/ha보다 11% 증수되었다. 6. 안풍의 엑스함량은 46.3%, 데쿠루신은 3.48%, 데쿠루시놀 안젤라이트는 2.79%로 주요성분 모두 만추당귀 보다 높았다.

• 한국한의학연구원논문집
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• 제14권3호
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• pp.57-63
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• 2008

Glehnia littoralis (Umbelliferae) is the medicinal plant used traditionally for treatment of immune-related diseases. Prostaglandins and nitric oxide (NO) have been implicated as important mediators in the processes of inflammation and carcinogenesis. For understanding the mechanisms for pharmacological activities of Glehnia littoralis, we evaluated the inhibitory activity of Glehnia littoralis on lipopolysaccharide (LPS)-induced prostaglandin $E_2$ ($PGE_2$) and NO production in mouse macrophage RAW264.7 cells. The results showed that the extract of Glehnia littoralis inhibited LPS- induced $PGE_2$ production effectively, but not NO. Additional study revealed that the extract of Glehnia littoralis suppressed cyclooxygenase-2 (COX-2) expression in a dose-dependent manner. Present study suggests that Glehnia littoralis may have anti-inflammatory and/or cancer chemopreventive activity through the inhibition of $PGE_2$ production by the suppression of COX-2 activity.

• 대한한방부인과학회지
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• 제23권1호
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• pp.65-71
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• 2010

Purpose: To suggest for the following experimental study of antioxidant by reviewing recent oriental medicine journals that have been published since 2007 in Korea. Methods: We investigated various types of studies in relation to antioxidant through 79 articles that have been published from 2007 to 2009 in recent oriental medicine journals were registered National Research Foundation of Korea. Results: In this study, most of studies performed using herbs or medicinal plant for medical disorder such as liver, Cardiac & Vascular, Diabetes Mellitus etc. Most of these herbs have positive effects against oxidative stress and free radicals. Conclusion: This result will provide useful information of field of Oriental medicine for the development of new anti-oxidative prescriptions or antioxidant. We will have to carry out comparative study between each herbs or each extract method.

• 한국약용작물학회지
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• 제15권1호
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• pp.21-25
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• 2007

해당화 뿌리는 우리나라 민간에서 당뇨병 치료제로 사용되는 약용식물이다. Bromobenzene으로 간독성을 유발한 흰쥐에 뿌리에서 분리한 화합물인 (+)-catechin을 경구투여하여 bromobenzene대사계에 미치는 효소활성을 간독성 물질인 bromobenzene 3,4-oxide 생성에 관여하는 효소인 aminopyrine N-demetylase와 aniline hydroxylase와 독성 epoxide 대사중간체를 무독화 시키는 epoxide hydrolase와 glutathione S-transferase에 활성을 관찰하였다. (+)-Catechin의 투여가 aminopyrine N-demetylase, aniline hydroxylase 및 glutathione S-transferase에 활성에는 영향을 주지 못하였으나, epoxide hydrolase는 positive control로 사용한 ascorbic acid에 미치지 못하지만, bromobenzene 처리군 보다 39% 효소활성을 회복 시켰다. 따라서, (+)-catechin은 간독성 물질을 무독화시키는 epoxide hydrolase의 활성을 회복시켜 간보호 활성을 나타냄을 알 수 있었으며, 해당화에서 분리한 사포닌 성분인 rosamultin도 이효소의 활성을 증가시킴으로 인해 보호활성을 나타내는 것으로 보고된바 있다.

• 대한본초학회지
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• 제28권3호
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• pp.85-93
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• 2013

Objective : For the purpose of developing Korean herbalogy of the plants to Iridaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. Methods : The examined herbalogical books and research paper which published at home and abroad. Results : A list was made about Iridacease plant which are cultivated or grew naturally in Korea, after investigate the data on domestic and foreign Iridaceae plants. Out of those lists, serviceable plants were selected and with those available plants, their distributions were analysed and parts which can be used as medicines were divided into 3 categories such as oriental medicine name, scientific name and non-official name. Iridacease's properties flavor, channels they use and effects were also noted, not to mention their toxicity. Iridacease (grew in Korea) was divided into 6 classes with 32 species. Out of those, 5 classes with 11 species were found serviceable which indicates 34% of all. Out of all 32 specified Iridacease plants, Iris plants were found 27 species, which were shown the most. And 7 classes of Iris plants were also selected the most in serviceable Iridacease. Out of all serviceable parts in Iridaceae, root parts took first place as 6 species. Conclusion ; There were totaled to 6 genera and 32 species in Iridaceae in Korea and among them medicinal plants are 5 genera, 11 species, some 34% in total.

• 대한본초학회지
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• 제28권4호
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• pp.41-48
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• 2013

Objectives : For the purpose of developing Korean herbalogy of the plants to Iridaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. Methods : The examined herbological books and research paper which published at home and abroad. Results : A list was made about Eriaceae plant which are cultivated or grew naturally in Korea, after investigate the data on domestic and foreign Eriaceae plants. Out of those lists, serviceable plants were selected and with those available plants, their distributions were analysed and parts which can be used as medicines were divided into 3 categories such as oriental medicine name, scientific name and non-official name. Eriaceae's properties flavor, channels they use, effects, and toxicity were also noted. Eriaceae (grew in Korea) was divided into 9 classes with 48 species. Out of those, 3 classes with 14 species were found serviceable which indicates 29% of all. Out of all 48 specified Eriaceae plants, Rhododendron plants were found 26 species, which were shown the most. And 7 classes of Rhododendron plants were also selected the most in serviceable Eriaceae. Out of all serviceable parts in Eriaceae, leaf parts took first place as 12 species. Conclusion : There were totaled to 9 genera and 48 species in Iridaceae in Korea and among them medicinal plants are 3 genera, 14 species, some 29% in total.