• 대한예방한의학회지
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• 제4권2호
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• pp.25-56
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• 2000

Trace element are involved in enzymatic activities, immunological reactions. physiological mechanisms. Deficiency in some trace elements, such as iron and iodine. is still an important health problem, The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. However, the importance of trace elements as chinese herbal constituents is not sufficiently appreciated by the oriental medical profession, although in recent years a significant increase of new finding on their essential character in chinese herbal medicine occurred. It is well known that herbal medicine contains a variety of trace elements which would show therapeutic effects with active components in herbal medicine . In china, recent work showed some positive correlation between trace element and traditional chinese medicine (TCM) in terms of therapeutic effects even if their role in therapeutic effects is still obscure. In korea, not much attention has been on the therapeutic importance of trace element contained in herbal medicine Here, the therapeutic effects of trace element in TCM were reviewed and summarized. 1. Iron, copper, zinc and manganese are mainly contained in TCM. In addtion, chromium, magnesium, molybdenum, nickel, alminium, cobalt, arsenic and selenium has been studied for their therapeutic effects 2. Zinc, is decreased in patients who have deficiency of kindney(腎虛) and chronic disease. Fe is decreased in patients who have deficiency of blood(血虛). However copper is increased in patients who have chronic disease and hepatic disease.3 Iron concentration is high in herbs used for tonifying and nourishing yin or blood(補陰補血藥) Zinc concentration is high also in herb used for tonifying kidiney and vital essence(補腎補精藥). In addition. copper concentration Is high in herb used for replenishing qi(補氣藥) 4 In herbal drugs, the therapeutic substances in TCM are not only organic but also inorganic. It seems that trace elements would be one of components in herb for its therapeutic effects. This indicates that therapeutic effects of TCM should be extended not only to herb itself, bur also to trace elements contained in herb.

• 대한예방한의학회지
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• 제10권2호
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• pp.131-145
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• 2006

Perilla frutescens is known as the herb helps digestion, tonifies stomachache, and decreases fever in oriental medicine. And it is reported it possess the anti-pyretic effect, anti-inflammatory effect, anti-allergy effect, anti-tumor effect etc. The components isolated from this herb consist of perilla aldehyde, d-limonene, ${\alpha}-pinene$, cyanin, linoleic acid, palmitic acid, menthol, rosmarinic acid and luteolin etc. But there is no effective tools to determine the quality of this herb. In this study, we aimed to analyze the changes of liquid chromatogram pattern, one of major standardization method, to determine the quality of Perilla frutescens.

• 혜화의학회지
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• 제14권2호
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• pp.171-176
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• 2005

Objective : The purpose of this study is to report to treat the patient who had numbness, paresthesia, pain after hip fracture in the category of Bi. Methods : The patient was treated by acupunture, moxibustion and herb medication. Conclusion : Pain, numbness, paresthesia belongs to Bi in the oriental medicine and the case that complains pain especially is Tong Bi. We experienced that improvement of the circulation the blood and gi, adding energy by acupuncture, moxibustion and herb medication have the effect treating Bi.

• 대한한방부인과학회지
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• 제25권4호
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• pp.161-170
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• 2012

Purpose: This study was to report the effect and safety of oriental medical treament in the pregnant woman diagnosed to herniated of nucleus pulposus(HNP) at L-spine. Methods: The patient was diagnosed with HNP at L-spine during Pregnancy. She was treated by herb medicine, acupuncture and moxibustion. Their symptoms was disappeared. Results: After treatment, most symptoms decreased, VAS score changed 10 to 2, ODI changed 41 to 20. Conclusions: The oriental medical treament(herb medicine, acupuncture and moxibustion) relieves HNP at L-spine during Pregnancy.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2019년도 추계학술대회
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• pp.103-103
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• 2019

Glycyrrhizae radix, commonly known as licorice, is a perennial herb belonging to Leguminosae and also includes various components such as, glycyrrhizin, liquiritin, liquiritigenin and isoliquiritigenin etc. Licorice has been widely used in East Asia as a medicine having pharmacological effects like antioxidants, anti-bacterial, anti-inflammatory, anti-cancer and immune modulatory activities. Among various licorice, Glycyrrhiza (G.) uralensis G. glabra and G. inflata are used for pharmaceutical purposes in Korea. However, cultivation of licorice has some problems such as low quality, low productivity, and early leaf drop. Korea Rural Development Administration developed new cultivars Wongam and Sinwongam, which are improved in cultivation and quality. To register the newly developed cultivar (s) on Ministry of Food and Drug Safety in Korea as a medicine, it is necessary to prove the similarity and difference through the comparative studies between already-registered species and new cultivars. Some fungi and bacteria usually in the human oral cavity and intestines exist as harmless state in human body. Also, the skin and genital infections by fungi can lead to toxic systemic infections and are accompanied by flushing, rashes, burning or painful sensation. The influences of licorice varieties on fungi and bacteria might be an evidence to prove the outstanding effect of newly developed licorice variety. In this study, the antifungal and antibacterial activity was investigated using newly developed licorice varieties Wongam, and Sinwongam against various fungi and bacteria. These results means newly developed licorice could be used as a replacement of already-registered species in terms of antifungal and antibacterial application.

• 식물분류학회지
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• 제47권1호
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• pp.6-10
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• 2017

Microsatellite markers were isolated for Daphne kiusiana var. kiusiana (Thymelaeaceae), an evergreen broad-leaved shrub endemic to Korea and Japan. Because its populations in Jeju Island are morphologically controversial, and consistently threatened by anthropogenic pressures, taxonomic delimitation and conservation effort are required at the genetic level. We developed 21 polymorphic microsatellite loci from Next Generation Sequencing data. The primer set included di-, tri-, and tetra-nucleotide repeats. Variability in the markers was tested for 80 individuals of D. kiusiana from three natural populations in Jeju Island and Japan. Among the 21 loci, three were unavailable for population JKJU of Japan. The Neighbor-Joining tree based on microsatellite markers described here classified the three populations into two groups according to geographical or morphological traits. These will be a powerful genetics tool for determining the taxonomic boundary and establishing suitable conservation strategies for D. kiusiana in Jeju Island.

• 대한한의학회지
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• 제41권3호
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• pp.151-161
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• 2020

Objectives: The purpose of this study is to report the improvement of multiple rib fracture after korean medical treatment; adhesive treatment and herb-medicine treatment. Methods: A patient with multiple rib fracture was treated with Daewhangchija-paste(大黃梔子膏) adhesive and herb-medicine treatment. Verbal numeric rating scale, medical examination by interview and rib series x-ray were used to assess progress of treatment. And we took pictures of left flank after attaching Daewhangchija-paste to observe the changes of the skin colors. Results: Rib series x-ray taken after 2 months of treatment revealed hard callus which added stability against external force on rib cage. After taking off Daewhangchija-paste, left plank skin turned into blue, green and yellow. And the pain level(VNRS) of left plank decreased from 10 to 0.5 for 4 months. Conclusions: Pain reduction on trauma site and improvement of general health condition were observed during combination treatment of Daewhangchija-paste adhesive and herb-medicine.

• 대한한방소아과학회지
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• 제18권2호
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• pp.127-142
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• 2004

Objective : To evaluate the effect of Oriental medical treatment on a patient with Ramsay Hunt syndrome with poor prognosis on EMG. Methods : We applied various methods of Oriental Medical treatment including Acupuncture, Electroacupuncture, Herb medicine, Vesiculation therapy using Mylabris and Crontonis Fructus, Massage, Self-excercise of face muscles. Results : 1. Herb medicine was applied on the basis of Differentiation of Syndromes(辨證): We tried Herb medicine to improve the function of Digestive System. The patient's stool condition, subjective sensation related with abdominal pain and general condition improved. 2. We used the Vesiculation therapy using Mylabris which was used traditionally to treat Facial Palsy. We powdered Mylabris and mixed it with Crontonis Fructus to make a paste. We put it on Ye-poong(?風), Nae-gwan(內關) at left side. It induced vesicles at the applied area, but it disappeared in 48 hours without any scar. 3. We applied acupuncture, electroacupunture, massage and self-excercise of face muscles. On gross scale assessment, there was some improvement. And assessment with regional scale also showed changes. The patient and the guardian were satisfied with the result. Conclusion : We experienced a case of Ramsay Hunt syndrome with poor prognosis on EMG. She also showed poor response to conservative treatment. Through various modalities of Oriental medical treatment, we attained some clinical improvement.

• Journal of Acupuncture Research
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• 제18권5호
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• pp.11-23
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• 2001

Objective : This study is designed to evaluate the clinical effect of the oriental medical treatment (Ex: chuna, physical theraphy, acupuncture, moxibustion, herb medicine, etc.) on patient of scoliosis. Methods : We investigated 12 patients with scoliosis who visited to Department of Acupunture & Moxibustion, Tae gu Oriental Hopital of Kyung San University from January 2000 to September. 12 patients had a diagnosis of scoliosis by X-ray. We treated 12 patients by the oriental medical treatment (Ex: chuna, acupuncture, physical theraphy, moxibustion, herb medicine, etc.)and they were evaluated with post treatment X-ray findings. Results : 1. We investigated 6 female and 6 male patients. The most commom distribution of age was 30's. 2. In the scoliosis angle : before treatment, the average scoliosis angle was $13.56^{\circ}$ but after treatment, it was decreased to $9.31^{\circ}$ and the mean correctability was 33.47%. 3. The more servious the symptoms were, the lesser the correction rate was. It was decreased in the order of Gr I, Gr II, Gr III and Gr IV. 4. The larger the scoliosis angle and the degree of rotation were, the lesser the correction rate was. Conclusion : These results suggest that the oriental medical treatment (Ex: chuna, acupuncture, physical theraphy, moxibustion, herb medicine, etc.) was effective treatment modality on patient of scoliosis.

• 대한한방부인과학회지
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• 제25권2호
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• pp.185-199
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• 2012

Objectives: This study aimed to review the effects and treatment of Korean, Oriental, Chinese medicine for premenstrual syndrome(PMS) as preceding research in order to further research the effective Korean Medicine treatment for PMS. Methods: Databases from Jan., 2002 through Feb., 2012 were searched through Pubmed for international journals; Korean studies information service system(KISS), National Discovery for Science Leaders(NDSL), Journal of Korean Acumoxa, J of Oriental Obstetrics and Gynecology, J of Meridian and Acupoint, and J of Korean Oriental Medicine for Korean journals were searched for national journals. The following search terms were used: acupuncture premenstrual syndrome, alternative medicine premenstrual syndrome, traditional Chinese medicine(TCM), premenstrual syndrome for Pubmed, premenstrual syndrome(in Korean and English) for the remaining search. Results: Twenty four studies were included in this review. Conclusions: Alternative medicinal intervention such as acupuncture and herb medicine may be effective treatment method in controlling premenstrual syndrome and premenstrual dysphoric disorder(PMDD).