• 대한한방소아과학회지
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• 제30권3호
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• pp.52-60
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• 2016

Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: "allergic rhinitis", "traditional Chinese medicine", "traditional Korean medicine", "Chinese herbal medicine", "randomized controlled trial", "clinical study", "nasal spray", and "nasal drop" Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.

• 한방비만학회지
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• 제6권2호
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• pp.113-120
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• 2006

Objectives : The purpose of this study was to investigate the clinical application of Starvation and coffee enema and oriental medical therapy to a patient with obesity caused by overeating and lack of exercise. Methods : This study was carried out on a patient who had obesity caused by overeating and lack of exercise, and whose body weight was reduced through starvation, coffee enema and oriental medical therapy. After checked body weight, we analyzed effect of starvation, coffee enema and oriental medical therapy. Results and conclusions : Following the treatment the patient's body weight was reduced. The present results suggest that starvation coffee enema and oriental medical therapy has positive effects on an obese patient

• 대한한의학원전학회지
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• 제18권3호통권30호
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• pp.70-80
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• 2005

1) Objective External treatments have various curative effects. So it had been used to cure various patients. But, it has a limited sphere of application in the present South Korea. Therefore we would like to bring out its sphere of application and detailed method in the oriental medicine classics. 2) Conclusions From long time ago people have used external treatment to cure various disease. According to the ${\lceil}Nei-Jing{\rfloor}$, hot compress therapy, fumigation therapy and bathing therapy had been used to cure blockage syndrome, muscle disease, carbuncle and cellulitis. Thereafter, a sphere of external treatment had gradually enlarged. (1) After all its sphere had included dermatologic, psychologic, internal, ophthalmic, otolaryngologic, obstetrics, gynecologic, pediatric and surgical diseases. (2) External treatment methods have contained hot compress therapy, fumigation therapy, bathing therapy, application therapy, medication bag therapy, medication plug therapy, medication massotherapy, aroma therapy and so on. (3) Medication types of external treatment have contained ointment, juice, infusion, powder, suppository and so on.

• 한방안이비인후피부과학회지
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• 제19권2호
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• pp.192-201
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• 2006

Objectives : Recently, He-Ne laser has been used for clinical purpose. We study the medical basis of He-Ne laser therapy and We make a proposal concerning the clinical application of using He-Ne laser in Medicine. Methods : We have selected data related to He-Ne laser therapy and study how to use He-Ne laser in clinic. Results : In biology, He-Ne laser therapy has been effects of an improve in skin regeneration an improve in peripheral and central nerve regeneration an improve in muscle regeneration, an anti-inflammation an alleviation of pain and a bone repair. In oriental medicine, He-Ne laser has been used to laser acupuncture and laser oriental physical treatment. In clinic, He-Ne laser have been used to care several parts like as facial palsy, facial spasm, trigeminal neuropathy, rhinitis and tinnitus. Recently, there is argument that He-Ne laser therapy is suitable to medical insurance. Conclusions : Laser therapy in oriental medicine is widespread and We can apply He-Ne laser to facial palsy, facial spasm, trigeminal neuropathy, rhinitis, tinnitus by using laser acupuncture or laser oriental physical treatment. Till now the whole mechanisms are not fully understood, so we hope to study these mechanisms actively and make suitable to medical insurance device in the near future.

• 대한한의학회지
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• 제32권4호
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• pp.68-74
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• 2011

Objective: The purpose of this study is to expatiate on high performance thin layer chromatography (HPTLC) as a simple, easy and scientific method for evaluation and standardization of herbal formulae. Methods: Through retrieving HPTLC application for herbal formulae in the literatures, the current situation of HPTLC application, and potential as well as limitation of HPTLC as a standardization method for multi-herbal drug was studied. Results: HPTLC is a speedy, inexpensive and well-operable tool for possessing multi-capability on component identification, separation, quantification and purification compared to other methods, such as high performance liquid chromatography (HPLC), gas chromatography (GC). Conclusions: HPTLC is considered as an available and convenient method for quality control and standardization of multi-herbal drugs. Thereby, this method could be recommended to widely applicate in the traditional Korean medicine.

• 동의신경정신과학회지
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• 제17권3호
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• pp.175-181
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• 2006

The purpose of this study is to investigate the clinical application of oriental medical therapy for Insomnia due to Qi and Blood deficiency and insufficiency of Heart. In this case, we treated the patient with insomnia by oriental medical therapy, specially Insamyaogyung-tang(人蔘養榮湯) and Gong-jin-dan(拱辰丹), And we checked patient's sleeping time. In result, at the first time, the patient slept only one hour. After oriental medical therapy, the patient slept over 6 hours, Conclusionally oriental medical therapy, specially Insamyaogyung-tang(人蔘養榮湯) and Gong-jin-dan(拱辰丹) is very helpful for the patient of insomnia due to Qi and Blood deficiency, and insufficiency of Heart.

• Journal of Acupuncture Research
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• 제19권1호
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• pp.54-64
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• 2002

Objective : The one of the main cause in back pain & sciatica is HNP of L-spine. This study is for taking data for the clinical application of Bee-Venom Acupuncture on HNP of L-spine. Methods : This clinical study was carried out 24 patients with HNP of L-spine, who had been admitted from March, 2001 to November, 2001. We devided the patients into two groups; One was an experimental group, treated by 2 methods-common acupuncture therapy and Bee-Venom Acupuncture. The other was an control group, treated only by common acupuncture therapy. Results and Conclusion : In an experimental group, there were 4 excellent cases (33.33%) and 5 good cases(41.67%). In an control group, there were 2 excellent cases (16.67%) and 5 good cases (41.67%). We thought that it needed to prove effects of Bee- Venom Acupuncture for efficient application by more clinical data from now.

• 대한한의학방제학회지
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• 제25권4호
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• pp.483-497
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• 2017

Background : Behavioral stress has been suggested as one of the significant factors that is able to disrupt physiological systems and cause depression as well as changes in various body systems. The stressful events can alter cognition, learning, memory and emotional responses, resulting in mental disorders such as depression and anxiety. Results : We used a restraint stress model to evaluate the alteration of behavior and stress-related blood parameter. The animals were randomly divided into two groups of five animals each group. Furthermore, we assessed the change of body weight to evaluate the locomotor activity as well as status of emotional and anxiety in mice. After 7 days of restraint stress, the body weight had significantly decreased in the restraint stress group compared with the control group. We also observed stress-associated behavioral alterations, as there was a significant decrease in open field and forced swim test, whereas the immobilization time was significantly increased in the stress group compared to the control group. We observed the morphological changes of neuronal death and microglia by immunohistochemistry and western blot. In our study restraint stress did not cause change in neuronal cell density in the frontal cortex and CA1 hippocampus region, but there was a trend for an increased COX-2 and iNOS protein expression and microglia (CD11b) in brain, which is restraint stress. Conclusion : Our study, there were significant alterations observed in the behavioral studies. We found that mice undergoing restraint stress changed behavior, confirming the increased expression of inflammatory factors in the brain.

• 대한한의학방제학회지
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• 제28권2호
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• pp.157-167
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• 2020

Objectives : The purpose of this clinical study was to investigate the efficacy and safety of Hwangryunhaedok-tang on the gastritis treatment. Methods : A total of 20 subjects who visited Pusan National University Hospital from April 2nd, 2019 to September 2nd, 2019 were included. In this study, we evaluated the individual symptoms through questionnaires, laboratory test, BIA (Bioelectrical Impedance Analysis), and adverse reaction according to medication. Statistical analysis was performed with paired t-test and Wilcoxon Signed Rank test. Statistical significance was achieved if the probability was less than 5% (p < 0.05). Results : After medications, the total score of individual symptoms, primary outcome, was significantly decreased. In particular, individual symptoms such as upper abdominal pain, bloating, heartburn and trim showed significant improvement. However, no statistically significant differences were found in nausea/vomiting and anorexia. In additions, the laboratory test showed a statistically significant decrease in total cholesterol, but no statistically significant differences in results of BIA. In the safety evaluation, adverse reactions were not reported. Conclusions : Considering this results, we have confirmed the possibility of Hwangryunhaedok-tang to the gastritis treatment.

• 동의신경정신과학회지
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• 제17권1호
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• pp.145-152
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• 2006

The purpose of this study was to investigate the clinical application of oriental medical therapy to Pick's disease We treated the patient with oriental medical therapy. The recovery of the dementia was evaluated by Korean-Mini Mental State Examination(MMSE-K), Korean-dementia Rating Scale(K-DRS) & Barthel ADL Index.(ADL) The applicability of oriental medical therapy has positive effects on the patient with Pick's disease. The Sum of MMSE-K score was increased. K-DRS & ADL were also promoted.