• Title/Summary/Keyword: organization absorption

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The Suggestion of Seismic Performance Values on Connections for Performance Based Design of Steel Structures (강구조 성능기반설계를 위한 접합부의 내진성능평가치 제안)

  • Oh, Sang-Hoon;Oh, Young-Suk;Hong, Soon-Jo;Lee, Jin-Woo
    • Journal of Korean Society of Steel Construction
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    • v.23 no.2
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    • pp.147-158
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    • 2011
  • The purpose of this research was to analyze the connections of the seismic-performance values for domestic-performance-based designs. Basic research on the performance design method has been increasing of late, along with performance-based organization investigations. These investigations concern the performance level state of steel structure buildings. According to the performance limit state, seismic-performance values should be presented as appropriate steel structure engineering amounts. The first step, based on the full-scale steel structure experiments, involves researching on the making of a basic document. The moment-rotation angle relationship results of the experiment on the moment-frame connection were used to assort the functional and undamaged limits, which were assumed to be less than the yield moment. Moreover, the repairable and safety limits, which were assumed to exist between the yield and maximum moments, were assorted by investigating the accumulated plastic deformation ratio.

Gerneral concept of dietary fiber and it's functionality (식품 중 식이섬유(Dietary fiber)의 의미와 기능성 고찰 -식이섬유의 특성과 기능을 중심으로-)

  • Shin, Dong-Hwa
    • Food Science and Industry
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    • v.52 no.1
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    • pp.84-99
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    • 2019
  • Dietary fiber is defined as soluble and insoluble polysaccharide consisted in the plant cell wall-associated fibers naturally occurring in fruits, vegetables, and cereal products, and of isolated fibers that are added to processed foods which are also artificially modified. There are so many difference types of dietary fibers as arabinoxylan, polydextrose chicory, oligosccharide. inulin, pectin, bran, cellulose, ${\beta}$-glucan, resistant starch and some seaweed polymers as alginate. Most of them provide many biological benefits in the intestine, as lower risk for developing coronary heart disease, stroke, hypertension, diabetes, obesity and some of the gastrointestinal disease like as colon cancer. And also lowering cholesterol levels, improves glycemic and insulin sensitivity to non-diabetic and diabetic persons including immune system. Beside of many benefits, average consumers in developed and under developing countries take far less amounts of dietary fiber that international organization recommended. Adequate intake of dietary fiber is 14g/1,000kcal base using the energy guide line of 2,000kcal/day for women and 26,000 kcal/day for men, dietary intake is 28g/day of adult women and 36g/day for adult men. The mechanisms behind the reported effects of dietary fiber on metabolic health are not fully well established. It is suggested that changes in intestinal viscosity resulting mucus increasing, macro-nutrients absorption, rate of passage of large intestinal, production of short chain fatty acids by fermentation. Production of gut hormones and changes of microbiota in intestine. It is necessary to do more research in this field in the future and combined interdisciplinary works together.

Computer-aided drug design of Azadirachta indica compounds against nervous necrosis virus by targeting grouper heat shock cognate protein 70 (GHSC70): quantum mechanics calculations and molecular dynamic simulation approaches

  • Islam, Sk Injamamul;Saloa, Saloa;Mahfuj, Sarower;Islam, Md Jakiul;Jahan Mou, Moslema
    • Genomics & Informatics
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    • v.20 no.3
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    • pp.33.1-33.17
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    • 2022
  • Nervous necrosis virus (NNV) is a deadly infectious disease that affects several fish species. It has been found that the NNV utilizes grouper heat shock cognate protein 70 (GHSC70) to enter the host cell. Thus, blocking the virus entry by targeting the responsible protein can protect the fishes from disease. The main objective of the study was to evaluate the inhibitory potentiality of 70 compounds of Azadirachta indica (Neem plant) which has been reported to show potential antiviral activity against various pathogens, but activity against the NNV has not yet been reported. The binding affinity of 70 compounds was calculated against the GHSC70 with the docking and molecular dynamics (MD) simulation approaches. Both the docking and MD methods predict 4 (PubChem CID: 14492795, 10134, 5280863, and 11119228) inhibitory compounds that bind strongly with the GHSC70 protein with a binding affinity of -9.7, -9.5, -9.1, and -9.0 kcal/mol, respectively. Also, the ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties of the compounds confirmed the drug-likeness properties. As a result of the investigation, it may be inferred that Neem plant compounds may act as significant inhibitors of viral entry into the host cell. More in-vitro testing is needed to establish their effectiveness.

Physical and Mechanical Properties of Magnesium Oxide Matrix depending on Addition Ratio of Magnesium Chloride (염화마그네슘 첨가율에 따른 산화마그네슘 경화체의 물리 및 역학적 특성)

  • Kim, Heon-Tae;Jung, Byeong-Yeol;Lee, Sang-Soo;Song, Ha-Young
    • Journal of the Korea Institute of Building Construction
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    • v.14 no.4
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    • pp.308-313
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    • 2014
  • Recently, for longevity of resident building, the main trend is that the change of the inside space organization of resident building from wall construction to rhamen construction, which resulted in increase in use of lightweight composite panel. Thus, in this study, authors analyzed the engineering property of oxide of magnesium depending on the magnesium chloride addition ratio. The results of this research is expected to contribute on providing a fundamental material for the surface materials of lightweight composite panel. As the result of the experiment, as fluidity increased, air content decreased and initial set and final set as the magnesium chloride addition ratio increase. In the aspect of flexural strength and compressive strength, the test specimen showed the highest strength at 40% of the magnesium chloride addition ratio. At 20% of the magnesium chloride addition ratio, the test specimen showed the lowest water absorption rate. As the magnesium chloride addition ratio increases, the expansibility tends to increase as well in the aspect of shrinkage strain. After observing microstructure, we can see hydration products in the form of needle. It appeared high flexural strength because the hydration products have mineral fibrous tissue shape, which also contribute to the cause of the expansibility.

A Study on the Development of the Triple helix and University-Business incubation (트리플 힐릭스와 대학 창업보육의 발전방안)

  • Seol, Myung Hwan;Choi, Jong In
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.13 no.3
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    • pp.99-112
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    • 2018
  • This research focuses on the university-business incubation from the prospective of triple helix and summarizes complementary researches and develop plans for university-business incubation. To pursue these objectives, we analyzed the studies of triple helix on domestic as well as overseas university-business incubators and their collaboration. The findings of this study showed that firstly In order to innovate the business incubator of the university, it is necessary to secure sufficient competence for the capability. For this purpose, Research and policy implications from various perspectives must be preceded.. Second, the collaborative relationship of business incubations should lead to organic and dynamic cooperative relations instead of static cooperative partnerships. Furthermore, based on the internal innovation that runs the business incubation program together with bottom-up rather than top-down approach, it is necessary to plan incubation and lead the transformation through creative ideas. Third, for the dynamic collaboration of business incubation, the management and practice of the organization should be given priority so that the boundary spanning appropriate to each situation, which turn increase the absorption capacity. As a future direction, studies are expected to explore the development of innovative university-business incubation about boundary spanning and knowledge transformation.

Research on the improvement of technology transfer agent system Through South Korea and China's technology transfer agent system comparison (한국과 중국의 기술거래사 자격제도 비교를 통한 기술거래사 제도개선에 관한 연구)

  • Kim, Hye-Sun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.7 no.1
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    • pp.165-175
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    • 2012
  • Recently, accumulation of technology, transfer, absorption, and commercialization is being significantly recognized as a key factor for sustainable growth of the 21st century global economy. The government established "Technology Transfer and Commercialization Promotion Act" In order that the technology developed at public research institutions can be transferred to the private sector and commercialized; the technology developed in the private sector can be traded and commercialized. Also, the Article 14 of "Technology Transfer and Commercialization Promotion Act" is concerning technology transfer agents' registration, promotion, and support: it introduced the special status system of technology transfer agents and the government registers, manages, and supervises it. In most developed countries, the technology transfer agency is transferred to the private sector and it is referred as a technology transfer agent or technology broker. In the domestic market, despite the introduction of the above special status system and the building a various organization and transfer medium system for boosting the market's revitalization, some problems occurred; because the registration system of a technology transfer agent and legal basis and system about its following-up control fall short. For example, recently technology transfer-related performance exemption has brought the activation of technology transfer agent's registration, but there was the limit of selecting the expert above a certain level. Therefore, some countermeasures for this are urgent, In addition, through a compulsory training completion system before the technology trade agent registration is prepared, a short period of curriculum was not sufficient to provide applicants various specialized knowledge. In this research, it is considered about the reform of technology transfer agent through its comparative study in China and Korea. Some improvements are suggested for expanding the market of technology transfer commercialization, assuring the agents' service and strengthening the competitiveness.

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A Survey on Asbestos Exposure Possibility in Indoor and Outdoor Environments of Childcare Centers (어린이집 실내·외 석면노출 가능성 조사에 관한 연구)

  • Park, Whame;Son, Byeung-Hun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.2
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    • pp.122-129
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    • 2014
  • Objectives: Because of its properties such as resistance to heat, chemicals and corrosion; tensile strength; sound absorption; and affordable price, asbestos has been widely used as a building material, fire resistant and retardant, thermal and heat insulator, soundproofing material, and electrical insulation. Since the prolonged inhalation of asbestos can cause serious illnesses such as lung cancer, mesothelioma, and asbestosis after an incubation period of 20 to 40 years, the mineral was classified as a Group 1 carcinogen by the International Agency for Research on Cancer, an intergovernmental agency forming part of the World Health Organization. Children and infants are more at risk than are adults if they are exposed to carcinogens, due to aweaker immunity that has not yet been fully developed. Most childcare centers are operated all day and children tend to spend a great amount of time in the centers. This is why it is important for them to be systematically isolated from environments that may expose them to asbestos. Materials: In order to understand both indoor and outdoor hazards to which children may have been exposed, the study focused on actual surveys of asbestos used in childcare centers, paying special attention to slate-roofed buildings in the vicinity of the centers. Results: A survey of a total of 211 childcare centers showed that the buildings of 18.1% of the centers contained asbestos, with 60.53% of the material being found in classroom ceilings. "Tex" was the most used material for ceilings, making up 89.47% of all ceilings. An outdoor survey showed that childcare centers in Daegu Metropolitan City had an average of 143 slate-roof buildings within a distance of 1km. Conclusions: Buildings housing mainly toddlers, children, teenagers and others more vulnerable to the toxicity of asbestos are not subject to asbestos investigation by law. A legal and practical basis for asbestos control is required for such buildings. In particular, housing materials which contain asbestos in day care centers require asbestos control. GIS should be used to identify the location of buildings with slate roofing materials in the vicinity of daycare centers in order to gauge toxicity of exposure to asbestos caused by potential asbestos friability possibility in outdoor conditions.