• 제목/요약/키워드: oral manifestations

검색결과 182건 처리시간 0.024초

Alternative Therapies with Tacrolimus and Low-Dose Doxycycline for Oral Chronic Graft-versus-Host Disease That Is Resistant to Topical Corticosteroid Medication: Case Report

  • Ju, Hye-Min;Ahn, Yong-Woo;Ok, Soo-Min;Jeong, Sung-Hee
    • Journal of Oral Medicine and Pain
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    • 제43권1호
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    • pp.16-20
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    • 2018
  • Graft-versus-host disease (GVHD) is frequent complications of hematopoietic stem cell transplantation. In the chronic GVHD (cGVHD), the oral cavity is the most commonly affected region. The clinical manifestations include erythema, ulceration, lichenoid-hyperkeratotic change in oral mucosa, dry mouth, and limitation of mouth opening. The initial treatment strategy of oral cGVHD patients is topical corticosteroid therapy in various formulation. However, corticosteroid resistance appears in some patients. We report a case of a 25-year-old male patient with oral cGVHD, who has resistance to topical corticosteroid medication, treated with 0.03% tacrolimus ointment and low-dose doxycycline. The patient showed subjective and objective improvement without side effect.

Oral Manifestation of Unknown Hematopoietic Malignancy

  • Hyun Jun, Oh;Buyanbileg, Sodnom-Ish;Mi Young, Eo;Ju Young, Lee;Kyung-Hoe, Huh;Soung Min, Kim
    • Journal of Korean Dental Science
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    • 제15권2호
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    • pp.162-165
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    • 2022
  • Burkitt lymphoma is a highly aggressive type of hematopoietic malignancy that is comparatively common in children and young people. It is important that Burkitt lymphoma be diagnosed as early as possible for prompt intervention due to its rapidly progressive, high-grade malignant nature. Dentists, especially maxillofacial surgeons, can play a life-saving role in patients with such unknown malignancy as the first clinical or radiological manifestation might occur in the oral region.

Mimicking Odontogenic Pain Caused by Burkitt's Lymphoma: A Case Report

  • Kim, Eui-Joo;Kim, Soung-Min;Park, Hee-Kyung
    • Journal of Oral Medicine and Pain
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    • 제42권3호
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    • pp.85-88
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    • 2017
  • Burkitt's lymphoma is a malignant monoclonal proliferation of early B-lymphocyte. Since Burkitt's lymphoma is a highly aggressive disease, early detection is a crucial. This disease often involves jaw and mandibular mass or swelling may also be seen, but in the early phase of Burkitt's lymphoma these symptoms cannot be observed. A rare case of Burkitt's lymphoma without any mandibular mass and the general symptoms was present. The excruciating toothache led the patient to visit the dental clinic and misdiagnosis of chronic periodontal abscess was made initially. Dentists should consider the oral manifestations of systemic disease when the multiple periodontal ligament space widening is observed and the dental treatment for mimicking odontogenic pain has no effect.

A Case of Aphthous Stomatitis in a Healthy Adult Following COVID-19 Vaccination: Clinical Reasoning

  • Kim, Hye Kyoung;Kim, Mee Eun
    • Journal of Oral Medicine and Pain
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    • 제47권1호
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    • pp.62-66
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    • 2022
  • Recent case studies raised the possibility that cutaneous and oral mucosal manifestations may be associated with the coronavirus disease 2019 (COVID-19) vaccination. A healthy 43-year-old male presented an acute aphthous stomatitis following Moderna COVID-19 vaccination. This rare case draws attention to a potential etiologic effect for oral mucosal manifestation from COVID-19 vaccination. Further investigation to shed light on prevalence and pathophysiologic association of this oral lesion and COVID-19 vaccination deserve attention.

중추 신경계 증상이 동반된 Behcet,씨 병 1예 (A case of Behcet's Disease with CNS Manifestations)

  • 신동구;고명구;윤경우;김종설
    • Journal of Yeungnam Medical Science
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    • 제3권1호
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    • pp.307-311
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    • 1986
  • Behcet씨 병의 경우 중추 신경계 침범여부는 조기에 진단 치료되어야 할 정도로 불량한 예후를 나타내는 지표로써 아프타성 구내염, 생식기 궤양, 표피성 혈관염, 포도막염, 활막염 등 전신적 증상에 주의를 기울임으로써 조기 진단 및 치료를 하여야 예후의 호전에 기여할 것으로 생각된다. 저자들은 51세 여자 환장서 중추 신경계 증상을 동반한 Behcet씨 병 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

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Ellis-van Creveld syndrome in an Indian child: a case report

  • Veena, K.M.;Jagadishchandra, H.;Rao, Prasanna Kumar;Chatra, Laxmikanth
    • Imaging Science in Dentistry
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    • 제41권4호
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    • pp.167-170
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    • 2011
  • Ellis-van Creveld syndrome is a rare congenital genetic disorder having autosomal recessive inheritance. It is a syndrome affecting the Amish population of Pennsylvania in USA with prevalence rate of 1/5,000 live at birth. In non-Amish population, the birth prevalence is 7/1,000,000. The syndrome is characterized by bilateral postaxial polydactyly of the hands, chondrodysplasia of long bones resulting in acromesomelic dwarfism, ectodermal dysplasia affecting nails as well as teeth and congenital heart malformation. There were very rare reports of this syndrome in dentistry. The present case focuses on the striking and constant oral findings of these patients, which are the main diagnostic features of this syndrome. Since the oral manifestations affect the esthetic, speech, and jaw growth of the child, the dentists have an important role to play in proper management of such case.

Adenomatoid odontogenic tumor of the mandible with unusual radiographic features: A case report

  • Narayanan, Veena S.;Naidu, Giridhar;Ragavendra, Raju;Mhaske-Jedhe, Shubangi;Haldar, Maya
    • Imaging Science in Dentistry
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    • 제43권2호
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    • pp.111-115
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    • 2013
  • Adenomatoid odontogenic tumor (AOT) usually presents as a unilocular, pericoronal radiolucency in the maxillary anterior region in adolescent females. Very few conditions occur in such a narrow age range and at such a restrictive site. Rarely, these tumors present with varied clinical features. A case of AOT of the mandible is reported with unusual features such as large size, multilocular appearance, and aggressive behavior. The role of radiology in diagnosis of atypical AOT is extremely important. The unique radiological manifestations of the lesion helped in the diagnosis, and it was managed conservatively with no evidence of recurrence.

Manifestation and treatment in a cleidocranial dysplasia patient with a RUNX2 (T420I) mutation

  • Lee, Chaky;Jung, Hee-sup;Baek, Jin-A;Leem, Dae Ho;Ko, Seung-O
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제37권
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    • pp.41.1-41.6
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    • 2015
  • Cleidocranial dysplasia is an autosomal dominant heritable skeletal disorder. The characteristic features of cleidocranial dysplasia (CCD) may include hypoplasia of the clavicle, delayed closure of frontanelles, late tooth eruption, and other skeletal disorders. This case report describes clinical and radiographic manifestations at the age of 11 and 29 of a CCD patient, investigates the mutation of core-binding factor A1 (CBFA1) based on gene analysis, and illustrates successful oral reconstruction with fixed prosthesis and dental implant after the extraction of multiple teeth.

Oral Manifestation of Paraneoplastic Pemphigus

  • Kim, Seurin;Park, In Hee;Park, YounJung;Kwon, Jeong-Seung;Choi, Jong-hoon;Ahn, Hyung-Joon
    • Journal of Oral Medicine and Pain
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    • 제44권3호
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    • pp.118-122
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    • 2019
  • Paraneoplastic pemphigus (PNP) is a rare and often fatal autoimmune blistering disease accompanied by both benign and malignant neoplasms. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by PNP patients. Oral ulcers are initial lesions in various autoimmune diseases like pemphigus, bullous pemphigoid, erythema multiforme, graft-versus-host, lichen planus, it does not improved despite of high-dose steroid therapy. We report a-35-year-old female who presented oral ulceration, lip crust and skin lesions. By doing several examinations, such as enzyme-linked immunosorbent assay, incisional biopsy with indirect immunofluorescence, she was diagnosed PNP with non-Hodgkin's lymphoma on pancreas.