• Journal of Digital Convergence
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• v.19 no.2
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• pp.315-322
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• 2021

The purpose of this study was to examine the correlations of oral myofunction and oral environment for the elderly with systemic diseases and to suggest need to improve oral health for the elderly. Data were collected from 64 elderly over the age of 65, from April to June 2019. Data were surveyed on general characteristics, oral myofunction, oral health-related quality of life, oral bacteria. Analysis was performed using PASW Statistics ver 18.0. The subjects were 43.8% systemic diseases, among them 40.6 percent of the people with more than two. The number of functional teeth was 18.6. Age was negatively correlated with functional teeth(r=-.384, p<.01) and tongue pressure (r=-).104, p<.001). Tongue pressure was a positive correlation with lip force(r=.279, p<.05). Age and total number of bacteria was negative correlation(r=-.336, p<.01). The functional teeth and total number of bacteria was positive correlation(r=.551, p<.001). The number of systemic diseases and total number of bacteria was positive correlation(r=.327, p<.01) the analysis of oral myofunction and oral bacteria in older patients with systemic diseases It was meaningful in suggesting a plan to improve oral health for the elderly. A practical policy plan was required to improve the quality of oral health life in a super-aged society.

• Biomedical Science Letters
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• v.25 no.3
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• pp.218-226
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• 2019

In old age, measures to cope with the natural phenomenon of aging and various diseases of the elderly due to the deterioration of physical function are also a challenge for this society. While interest in systematic health is increasing, it is true that awareness and interest in oral-related diseases is relatively lacking. This study aims to present basic data necessary to improve the quality of life for senior citizens aged 65 or older by improving the oral dryness caused by systemic health. By research method, improve oral dryness caused by whole-body health with the elderly over 65 and promote their oral health, inducing the increase of the salivary flow rate through oral health care education, oral exercise, and salivary gland massage. First, on the DMSQ according to the general characteristics of the elderly, the recognition of the whole body and oral health status, independent sample t-test and One-way ANOVA were conducted. Second, on changes in the salivary flow rate and saliva pH according to the general characteristics of the elderly, recognition of oral and whole-body health status, and whole-body health, paired samples t-test was conducted. Studies have shown that salivary gland flow increased significantly after oral exercise and salivary gland massage, the salivary flow rate significantly increased. In all variables of the recognition of the oral health status, the salivary flow rate increased after oral exercise and salivary gland massage, and in the whole-body health, regardless of hypertension, diabetes, cardiovascular disorders, and osteoporosis, the salivary flow rate increased after oral exercise and salivary gland massage, and the salivary flow rate increased after oral exercise and salivary gland massage if the subjects responded that they did not have thyroid abnormality, anemia, abnormalities of breathing, hypotension, gastrointestinal disturbance, or kidney diseases. As a comprehensive analysis of this study, many felt oral dryness when they had a problem with the whole-body health, and many felt oral dryness when they had a problem with oral health cognition. After applying oral exercise and salivary gland massage as intervention methods in the oral health care for the elderly, the salivary flow rate significantly increased, and it is judged that the methods were very effective for controlling oral dryness. Furthermore, it is judged that the factors affecting oral health, whole-body health, and oral dryness would be identified, which would be helpful for the promotion of whole-body health and oral health. It is judged that continuous research would be needed so that measures for the application of the oral care program and system for the elderly would be prepared in the future.

• Journal of Environmental Health Sciences
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• v.32 no.2 s.89
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• pp.192-197
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• 2006

This study was performed to investigate anti-microbial activity of soybean extract against oral microbes, and to determine the minimum inhibition concentration (MIC) for microbes causing oral diseases. The soybean extract was prepared using ethyl acetate and it was treated with 16 types of oral microbes at a concentration of 5.00 mg/ml (0.5%). The MIC of soybean extract for three major microbes causing oral diseases was determined. The anti-microbial activity and MIC were measured using broth dilution method. Significant reduction of microbial activities of 9 types oral microbes when the soybean extract was added to the broth compared to the control (p<0.01). The extract showed higher anti-microbial activity against some anaerobic strains (P. gingivalis and P. intermieia). S. mutans, which causes dental caries, showed MIC at a concentration of 40 mg/ml for the soybean extract. P. gingivalis, which causes adult periodontal disease, showed MIC at a concentration of 20 mg/ml for the extract. C. albicans, which causes denture stomatitis and angular stomatitis, showed MIC at a concentration of 20 mg/ml for the extract. These results indicate that soybean extract showed anti-microbial effort against 9 types of oral microbes, and the anti-microbial effect of the extract against oral microbes was stronger against fungi than against bacteria. The anti-microbial mechanism of soybean extract against oral microbes should be investigated, and more research for clinical application is required at a level of actual intake.

• The Journal of the Korean dental association
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• v.58 no.1
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• pp.45-49
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• 2019

Korean society is experiencing a very rapid change in population aging. Oral diseases, including dental caries and periodontal disease, are usually cumulative and make oral health worse with age. Preventing tooth loss through the prevention and treatment of caries and periodontal diseases are essential for retaining oral function later in life. This study aimed to identify the trend in oral health status among elderlies over 65 years old, using major oral health indicators of Health Plan 2020. The fifth, sixth, and seventh Korea National Health and Nutrition Examination Survey (KNHANES V, VI, VII) were used in the present study to estimate the number of remaining natural teeth, the rate of 20 or more natural teeth, the rate of chewing difficulty, and the rate of oral health check-up of elderly. The number of remaining natural teeth increased from 15.6 in 2010 to 17.1 in 2015, and the rate of 20 or more natural teeth also increased from 45.8% in 2010 to 53.7% in 2015. The rate of chewing difficulty was similar but declined a little from 44.3% in 2010 to 42.9% in 2017. Finally, the rate of oral health check-ups of the elderly increased significantly from 12.2% in 2010 to 21.1% in 2017.

• Journal of the Korea Convergence Society
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• v.11 no.10
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• pp.387-392
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• 2020

This study was to investigate the relationship of BMI, sleep time and experience of oral diseases in adolescents. We want to help develop basic data for improving oral health of adolescents. According to the sample design of the Youth Health Behavior online survey, a total of 57,303 adolescents were analyzed for frequency of composite samples, x2-test of composite samples, and logistic regression of composite samples, and the IBM SPSS Statistics 20.0 program was used and the significance level was 0.05. Results, BMI was associated with bad breath, and sleep time was associated with tooth break, pain, bleeding, and bad breath. Therefore, BMI and sleep time should be considered for the management and prevention of oral diseases in adolescents.

• International Journal of Oral Biology
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• v.49 no.1
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• pp.1-9
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• 2024

Oral bacterial infections substantially affect the development of various periodontal diseases and oral cancers. However, the molecular mechanisms underlying the association between Fusobacterium nucleatum (F. nucleatum ), a major periodontitis (PT)-associated pathogen, and these diseases require extensive research. Previously, our RNA-sequencing analysis identified a few hundred differentially expressed genes in patients with PT and peri-implantitis (PI) than in healthy controls. Thus, in the present study using oral squamous cell carcinoma (OSCC) cells, we aimed to evaluate the effect of F. nucleatum infection on genes that are differentially regulated in patients with PT and PI. Human oral squamous cell carcinoma cell lines OSC-2O, HSC-4, and HN22 were used. These cells were infected with F. nucleatum at a multiplicity of infection of 100 for 3 hours at 37℃ in 5% CO₂. Gene expression was then measured using reverse-transcription polymerase chain reaction. Among 18 genes tested, the expression of CSF3, an inflammation-related cytokine, was increased by F. nucleatum infection. Additionally, F. nucleatum infection increased the phosphorylation of AKT, p38 MAPK, and JNK in OSC-20 cells. Treatment with p38 MAPK (SB202190) and JNK (SP600125) inhibitors reduced the enhanced CSF3 expression induced by F. nucleatum infection. Overall, this study demonstrated that F. nucleatum promotes CSF3 expression in OSCC cells through p38 MAPK and JNK signaling pathways, suggesting that p38 MAPK and JNK inhibitors may help treat F. nucleatum-related periodontal diseases by suppressing CSF3 expression.

• Journal of Korean society of Dental Hygiene
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• v.16 no.1
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• pp.27-35
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• 2016

Objectives: The purpose of the study was to find out dental caries and periodontal disease based on oral healthcare of adults in Busan. This study will provide the preventive oral healthcare for the periodontal diseases and dental caries. Methods: The study subjects were 369 people from the regular dental health checkup in the general hospital in Busan. After receiving informed consent, a self-reported questionnaire was completed from October 1, 2014 to January 31, 2015. The questionnaire consisted of dental caries and periodontal diseases by direct examination and toothbrushing method. Data were analyzed by ${\chi}^2$ test, Fisher's exact test, and Pearson's correlation. Results: In the morbidity of dental caries and periodontal diseases, the dental caries was most common in those having restored teeth(236 subjects, 64%), while periodontal diseases were found in mild cases of gingival inflammation in 285 subjects(77.2%), and mild cases of dental calculus in 274 subjects(73.4%). Most of the respondents replied that they did not have systemic disease or oral health related symptoms. According to toothbrushing pattern, dental caries experiences were most common in those having less frequent toothbrushing less than 3 minutes and no tongue brushing. The outbreak of dental caries was more common in 5 times than 3 to 4 times a day. Conclusions: The education of the right toothbrushing method and use of dental floss is the most important prevention of dental caries and periodontal disease in the adults.

• Journal of The Korean Society of Integrative Medicine
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• v.12 no.2
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• pp.25-32
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• 2024

Purpose: This study utilizes big data from the 8th (2021) National Health and Nutrition Examination Survey to determine first, the relationship between chewing discomfort in the elderly and some systemic diseases and second, whether oral diseases and oral health problems are related to systemic diseases. Since this may have an impact, we aim to provide basic data to facilitate the expansion and emphasize the importance of integrated health management education. Methods: Original data from the 8th (2021) National Health and Nutrition Survey, conducted by the Korea Centers for Disease Control and Prevention, were analyzed using SPSS Version 21.0 (IBM). A complex sample frequency analysis was conducted to confirm the general and health-related characteristics of the study subjects, and a complex sample cross-analysis was conducted to determine chewing discomfort according to both general and health-related characteristics. Complex sample multiple logistic regression analysis was conducted to determine the effect on chewing discomfort. Results: In order to analyze the factors that affect chewing discomfort, the general characteristics that showed significant differences in chewing discomfort were adjusted for age, personal income, education level, basic livelihood security, high blood pressure, subjective health status, and subjective oral health. It was found that the condition had a statistically significant effect on chewing discomfort. Conclusion: The findings of this study demonstrate that high blood pressure, subjective health status, and subjective oral health status affect chewing discomfort; hence, measures such as developing and operating programs to improve national oral health are needed. We hope that our study will be used as basic data for research into chewing discomfort and systemic diseases in the elderly.

• Imaging Science in Dentistry
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• v.32 no.2
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• pp.81-87
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• 2002

Purpose : To investigate the diagnostic significance of cortical changes in the bone of diseased jaws utilizing computed tomography (CT). Materials and Methods: Computed tomographic images of 91 patients, consisting of 7 osteomyelitis, 46 cysts, 18 benign tumors, and 20 malignant tumors, were analyzed. The pattern of cortical expansion was classified into three types: no expansion (N), buccal or lingual expansion (B/L), and buccolingual expansion (B & L). The pattern of cortical destruction was classified into four types: no destruction (N), point destruction (PO), gross destruction (GR), and permeative destruction (PE). The pattern of periosteal reaction was classified into four types: parallel, irregular, spicule, and Codmans triangle. The relationship between the pattern of cortical bone changes and diseases of the jaws was assessed. Results: When the pattern of cortical expansion was compared to diseases of the jaw, N-type was most prevalent in cases of osteomyelitis and malignant tumors, B/L-type with cysts, and B&L-types with benign tumors. Comparison between the pattern of cortical bone destruction with diseases of the jaw showed strong correlations between PO and PE-types to osteomyelitis, N-type with cysts, N and GR-types with benign tumors, and GR-type with malignant tumors. Finally, the relationship between the pattern of periosteal reaction to diseases of the jaw showed a strong correlation between parallel-type to osteomyelitis and spicule-type to malignant tumors. Conclusion : The pattern of cortical expansion and cortical destruction is useful in differentiating diseases of the jaws.

• Journal of Technologic Dentistry
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• v.30 no.2
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• pp.121-133
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• 2008

The purpose of this study was to evaluate the role of socioeconomic factors and health behaviors on the prevalence of oral diseases(dental caries and periodontal disease) among Korean adults. Data from the 2005 National Health and Nutrition Examination Survey was analyzed for adults aged over 19 years (n=25,215). Oral disease was defined as disease diagnosed by a dentist for the previous 12 months. Chi-square test and logistic regression analysis were used to conduct statistical analysis. The population without dental caries and periodontal diseases were used as the reference category for all analysis. The overall prevalence of annual dentist-diagnosed dental caries and periodontal diseases were 23.5% and 10.6% respectively. The relative risk of developing dental caries for graduates of middle school and lower were 1.53 times (95% CI: 1.24-1.89) more likely to develop dental caries comparing to college graduates. Low income earners were 1.23 times(95% CI: 1.01-1.49) more likely to develop dental caries than high income earners. Persons covered by national medical insurance were 1.45 times(95% CI: 1.08-1.95) more likely to develop dental caries comparing to persons covered by employee medical insurance. Compared with persons not eating snacks, the risk of developing caries in persons eating snacks once a day was 1.16(95% CI: 1.01-1.32), while those who snacked twice or more a day were 1.19(95% CI: 1.01-1.41). The relative risk of developing periodontal disease was 3.71(95% CI: 2.38-5.80) higher in older individuals than younger. In terms of education level, middle school graduates and lower were 1.54 times more likely to develop periodontal disease than college graduates. Low income earners were 1.47 times more likely to develop periodontal diseases than high income earners. Using data from a large, nationally representative sample of Korean populations, we support the hypothesis that the prevalence of oral diseases is related with socioeconomic factors and health behaviors. More intensive intervention efforts to reduce the prevalence of dental diseases are warranted in Korea.