• International Journal of Aeronautical and Space Sciences
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• 제15권1호
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• pp.20-31
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• 2014

This paper deals with the development of a realistic shape optimization of damaged columns that are subjected to conservative and non-conservative forces, using the Genetic Algorithm (GA). The analysis is based on the design of the most optimized shape of the column under the constraint of constant weight, considering the Static, Vibrational, and Flutter characteristics. Under the action of conservative and non-conservative longitudinal forces, an elastic column loses its stability. A numerical analysis based on FEM has been performed on a uniform damaged column, to compute the fundamental buckling load, vibration frequency, and flutter load, under various end restraints. An optimization search based on the Genetic Algorithm is then executed, to find the optimal shape design of the column. The optimized column references the one having the highest buckling load, highest vibration frequency, and highest flutter load, among all the possible shapes of the column, for a given volume. A comparison is then made between the values obtained for the optimized damaged column, and those obtained for the optimized undamaged column. The comparison reveals that the incorporation of damage in the column alters its optimal shape to only a certain extent. Also, the critical load and frequency values for the optimized damaged column are comparatively low, compared with those obtained for the optimized undamaged column. However, these results hold true only for moderate-intensity damage cases. For high intensity damage, the optimal shape may not remain the same, and may vary, according to the severity of damage.

• ETRI Journal
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• 제38권2호
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• pp.291-301
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• 2016

In this paper, we study an optimized block-diagonal zero-forcing (BD-ZF) precoder in a two-tiered cognitive network consisting of a macro cell (MC) and a small cell (SC). By exploiting multiuser multiple-input and multiple-output Vandermonde-subspace frequency-division multiplexing (VFDM) transmission, a cognitive SC can coexist with an MC. We first devise a cross-tier precoder based on the idea of VFDM to cancel the interference from the SC to the MC. Then, we propose an optimized BD-ZF intra-tier precoder (ITP) to suppress multiuser interference and maximize the throughput in the SC. In the case where the dimension of a provided null space is larger than that required by the BD-ZF ITP, the optimized BD-ZF ITP can collect all limited channel gain by optimizing rotating and selecting matrices. Otherwise, the optimized BD-ZF ITP is validated to be equivalent to the conventional BD-ZF ITP in terms of throughput. Numerical results are presented to demonstrate the throughput improvement of the proposed optimized BD-ZF ITP and to discover the impact of imperfect channel state information.

• 소성∙가공
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• 제29권4호
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• pp.218-228
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• 2020

The prediction of final mass and optimized process conditions of injection molded products using Artificial Neural Network (ANN) were demonstrated. The ANN was modeled with 10 input parameters and one output parameter (mass). The input parameters, i.e.; melt temperature, mold temperature, injection speed, packing pressure, packing time, cooling time, back pressure, plastification speed, V/P switchover, and suck back were selected. To generate training data for the ANN model, 77 experiments based on the combination of orthogonal sampling and random sampling were performed. The collected training data were normalized to eliminate scale differences between factors to improve the prediction performance of the ANN model. Grid search and random search method were used to find the optimized hyper-parameter of the ANN model. After the training of ANN model, optimized process conditions that satisfied the target mass of 41.14 g were predicted. The predicted process conditions were verified through actual injection molding experiments. Through the verification, it was found that the average deviation in the optimized conditions was 0.15±0.07 g. This value confirms that our proposed procedure can successfully predict the optimized process conditions for the target mass of injection molded products.

• Smart Structures and Systems
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• 제21권2호
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• pp.207-223
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• 2018

In this inquisition, a passive damper namely Stockbridge Damper (SBD) has been introduced to the field of vibration control of Offshore Wind Turbine (OWT) to reduce the earthquake excitations. The dynamic responses of the structure have been analyzed for three recorded earthquakes and the responses have been assessed. To find an optimum SBD, the parameters of damper have been optimized using Response Surface Methodology (RSM) based on Box-Behnken Design (BBD) and Particle Swarm Optimization (PSO). The influence of the design variables of SBD such as the diameter of messenger cable, the length of messenger cable and logarithmic decrement of the damping has been investigated through response variables such as maximum displacement, RMS displacement and frequency amplitude of structure under an artificially generated white noise. After that, the structure with optimized and non-optimized damper has been analyzed with under the same earthquakes. Moreover, the comparative results show that the structure with optimized damper is 11.78%, 18.71%, 11.6% and 7.77%, 7.01%, 10.23% more effective than the structure with non-optimized damper with respect to the displacement and frequency response under the earthquakes. The results show that the SBD can obviously affect the characteristics of the vibration of the OWT and RSM based on BBD and PSO approach can provide an optimum damper.

• 한국항해항만학회지
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• 제35권2호
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• pp.159-165
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• 2011

The aim of paper is to calculate the optimized size of Mobile Harbor(MH) which would be operated in South Korea coast area. MH is the combined entity which has the function of both ship and container port. In estimating the optimized size, the total cost concept is applied to the different size of MH. Trade-off factors for calculating total cost are MH cost and the over-capacity lost cost. The factors for MH cost estimation are the cargo demand, distance from origin to destination, voyage route and MH's fixed and variable cost in both sailing and port. The other cost is the over-capacity lost cost which is occurred from dead space in case of oversize compared with a voyage demand. The alternatives for the least cost are 250TEU, 500TEU, 750TEU and 1,000TEU sized vessel. The result of research is that 250TEU sized vessel is optimized in a South Korea costal service. If the coastal area be separated in terms of voyage distance or the specific area in considering trade, the optimized size is changed depending upon distance.

• 복식
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• 제53권7호
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• pp.139-146
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• 2003

This study was aimed at analyzing a characteristics of the sewing machines and analyzing the effective sewing time in the garment manufacture process, therefore to obtain the basic data concerned with the sewing. operation standardization. The two methods were experimented. First, two garment factories established in Seoul and Geonggi province were randomly selected for the analyzing the sewing speed of the sewing operator for the optimized sewing speed using the equipment of Digital Tachometer HT4100. Second, five garment factories established in Seoul and Geonggi province were randomly selected to analyze the required time data to reach the fixed sewing speed using the lock stitch sewing machine which was used in the sewing factories. The results are divided into 3 categories as follows; 1) Survey results for the optimized sewing speed : The sewing operations of 10~20 cm range were most frequently selected in seam constructions in Korean sewing factories, and the sewing speed of 2,500 R.P.M was most used; 2) Required time to reach the fixed sewing speed using the lock stitch sewing machine : The mean of required time to the fixed sewing speed of 2.500 R.P.M was 3.5 second, and the mean of the real-sewing length during the 3.5 second was 43.8 cm ; 3) Analysis of the optimized sewing speed calculated using these results : The optimized sewing speed for the sewing manufacturers of the upward of 43.8 cm was 2,500 R.P.M. and for the sewing manufacturers of the below of 42.2 cm, the optimized sewing speed was 2.450 R.P.M.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.461-463
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• 2002

Image quality and selection of optimized window for good quality reconstruction in coronary angiography using multi-detector row CT (MDCT) have not been studied by heart rate and its variation. Therefore, the effect of heart rate and its variation was systemically analyzed. Eighty-three patients were undergone contrast-enhanced coronary angiography using MDCT. In this study, sixty cases were enrolled. Two radiologists graded image quality as follows: 4, excellent; 3, good; 2, fair; l, bad. The starting points of the reconstruction window were chosen at seventy and forty percent of R wave interval. Optimized window was scored as 1 when 40% reconstruction was better quality than 70%, as 2 when 40% reconstruction is same as 70%, and as 3 when 70% reconstruction was better than 40%. Regression analysis was performed. The range of variation of beats per minute (BPM) was well correlated with image quality (r=-0.55, p=0.000), however correlation with optimized window percentage was not statistically significant (p=0.969). By contraries, median value of BPM was comparatively well correlated with optimized window grade (r=-0.24, p=0.086). Median value of BPM was not well correlated with image quality (r=0.l70, p=0.l97). Image quality is more affected by variation of heart rate (VHR) than by higher heart rate. Selection of optimized reconstruction window for good image quality is mainly affected by heart rate and there is a tendency that systolic phase reconstruction is better in image quality than diastolic reconstruction in higher heart rate.

• Journal of Microbiology and Biotechnology
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• 제29권2호
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• pp.304-310
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• 2019

Interleukin-21 is a common ${\gamma}$-chain cytokine that controls the immune responses of B cells, T cells, and natural killer cells. Targeting IL-21 to strengthen the immune system is promising for the development of vaccines as well as anti-infection and anti-tumor therapies. However, the practical application of IL-21 is limited by the high production cost. In this study, we improved IL-21 production by codon optimization and selection of appropriate signal peptide in CHO-K1 cells. Codon-optimized or non-optimized human IL-21 was stably transfected into CHO-K1 cells. IL-21 expression was 10-fold higher for codon-optimized than non-optimized IL-21. We fused five different signal peptides to codon-optimized mature IL-21 and evaluated their effect on IL-21 production. The best result (a 3-fold increase) was obtained using a signal peptide derived from human azurocidin. Furthermore, codon-optimized IL-21 containing the azurocidin signal peptide promoted $IFN-{\gamma}$ secretion and STAT3 phosphorylation in NK-92 cells similar to codon-optimized IL-21 containing original signal peptide. Collectively, these results indicate that codon optimization and azurocidin signal peptides provide an efficient approach for the high-level production of IL-21 as a biopharmaceutical.

• 대한치과의사협회지
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• 제37권10호통권365호
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• pp.785-795
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• 1999

• Composites Research
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• 제18권4호
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• pp.52-58
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• 2005

사이클로콥터는 회전축에 평행하게 회전하는 블레이드로 구성된 사이클로이드 블레이드 시스템으로부터 추력을 얻는 수직이착륙 무인기이다. 본 논문에서는 공기역학을 고려한 최적 설계를 통해 결정된 형상을 갖는 사이글로콥터 로터에 대해서 구조적 관점에서 최적 설계를 수행하였다. 복합재료 블레이드의 적층각, 적층수와 스파 위치 등을 설계 변수로 하여 MSC/NASTRAN을 이용한 해석을 통해 데이터베이스를 구축하고, 반응면 기법 등에 의해서 최적의 조합을 결정하였다. 최적 설계된 블레이드와 복합재료로 구성된 허브암을 포함하는 로터에 대해, 정적 해석을 수행하여 각 요소가 허용 응력 이내의 값을 가짐을 확인하였고, 동적 해석을 통해 주요 저차 모드가 로터 회전과 불일치하게 함으로써 공진의 가능성을 없앴다.