• 한국가시화정보학회:학술대회논문집
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• 2007.11a
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• pp.71-76
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• 2007

Flow visualization of a droplet passing through a straight channel and a diverging channel has been carried out using micro-PIV. Diverging channel is frequently used in lab-on-a-chip and microfluidic devices, where flow pattern inside the droplet passing is quite different from that through a straight channel. In the present study, we visualized the droplet flow in three different regions. The first region is where the droplet has a wide contact area with the channel wall, the second region is characterized with a narrow contact area and the third region is where droplet is detached from the channel wall. Visualization results show that the internal flow inside the droplet passing through the straight channel moves in the opposite direction to the droplet velocity in the near wall exhibiting complex flow patterns. But in the diverging channel the internal flow inside the droplet moves in the same direction as the droplet velocity due to the shear induced by oil phase flow exhibiting rather simple flow pattern.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.356-358
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• 2002

MRI, particularly diffusion weighted imaging (DWI), plays vital roles in detection of the acute brain infarction$\^$1-4/ and others metabolic changes of biological tissues. In general, every molecule in biological tissues may diffuse and move randomly in three-dimensional space. However, in clinical diagnosis, only 2D-DWI is used. The authors have developed a new method for rapid three-dimensional DWI (3D-DWI). In this method, by refocusing of the magnetized spin with the applied gradient field, direction of which is opposite to phase encoding field. Magnetized spin of $^1$H is kept under the SSFP (steady state free precession)$\^$5-6/. Under SSFP, in addition of FID, spin echo and stimulated echo are also generated, so the acquired signal is increased. The signal intensity is increased depending on flip angle (FA) of magnetized spin. This phenomenon is confirmed by human brain and phantom studies. The performance of this method is quantitatively analyzed by using both of conventional spin echo DWI and 3D-DWI. From experimental results, three dimensional diffusion weighted images are obtained correctly for liquid phantoms (water, acetone and oil), diffusion coefficient is enhanced in each image. Therefore, this method will provide useful information for clinical diagnosis.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3803-3807
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• 2012

Prohibitin (PHB), an evolutionarily-conserved protein, has been found to be over-expressed in gastric cancer and be closely related with tumor malignancy. In this study, to investigate the relationship between PHB expression and cell apoptosis in the BGC823 gastric cancer cell line, low and high expression PHB in BGC823 cells was accomplished using RNA interference technology and gene transfer techniques. Cell proliferation, cell cycling, apoptosis, Bax, Bcl-2 and Cyt.c protein expression and the activation of Caspase-3,9 were assessed after 48h. Over-expression of PHB gene in BGC823 cells resulted in slow cell growth, cell arrest in G2 phase, and an increased apoptosis ratio while the opposite was found for PHB under-expressing cells. In PHB over-expressing cells, the expression of Bax gene was increased, the expression of Bcl-2 was decreased, the activation level of Caspase-3, 9 was increased, but the activation level of Caspase-8 demonstrated no change. These results indicate that PHB induced apoptosis through the mitochondrial pathway.

• Journal of computational fluids engineering
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• v.20 no.4
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• pp.109-115
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• 2015

In this study, the Stokes flow in the microchannel is analysed where the semicircular protuberances with constant spacing are attached on the upper and lower walls with staggered arrangement. For the low Reynolds number flow in microchannel, Stokes approximation is used and the periodicity and symmetry of the flow are considered to determine the stream function and pressure distribution in the flow field by using the method of least squared error. As results, the streamline patterns and pressure distributions in the flow field are shown for some specific values of the size and spacing of the protuberances, and shear stress distributions on the surface of semicircular protuberances are plotted. Especially, for an important physical property, the average pressure gradient along the microchannel is obtained and compared with that for the case of in-phase arrangement of the upper and lower protuberances. And, for the small clearance between the protuberances of upper and lower walls or between the protuberances and the opposite wall, the average pressure gradient is derived from the lubrication theory and compared with that of the present study.

• Proceedings of the Membrane Society of Korea Conference
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• 2002.04a
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• pp.23-46
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• 2002

The cryogenic, pressure swing adsorption and membrane methods have been used to separate air into nitrogen and oxygen. The air separation membrane is made of the polymers, of which manufacturing process is complicate and it causes a little high production cost. Polymer membrane has temperature limit in usage and low durability even at moderate temperature. Therefore, inorganic membranes have been studied for years. As formation of unit alumino-silicate membrane, unit cells of membrane were made with a few coating methods. In this study the dipping of substrate into sols, application of vacuum to the opposite side of substrate with coating and rotating of the substrate in the sols were found as good coating memthods to make a uniform coating and to control the thickness of membrane. The membrane coats were examined by SEM and XRD. The sample ESZl-1 was compared with those of samples that prepared by another method. The present developed coating methods could be applied to the various types of zeolite membrane formation, that is A- X-, Y- ZSM- and MCM-types of membranes. Also these membrane forming methods could be applied to formation of catalyst absorbed zeolite membrane, of which zeolite absorb the catalytic metals. The product obtained from these coating methods could be applied to the industrial gas and liquid phase catalytic reaction and separation processes.

• Journal of the Korean Regional Science Association
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• v.13 no.2
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• pp.45-54
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• 1997

A regional economy is characterized as a spatial economy. However the literature shows that it has been treated as a point economy since space is little recognized in regional modeling due to mathematical complication. This leads to the fact that regional model does not sufficiently represent regional characteristic. This paper attempts to construct a regional growth model in a partial equilibrium framework specifically taking into consideration land as a primary factor. The model is formulated largely neoclassical. Labor is assumed to move in response to differences in the wage rate, while capital is perfectly mobile across regions. The paper shows that two growth equilibrium points exist, one stable equilibrium point and the other unstable equilibrium point. The unstable growth equilibrium indicates the existence of minimum threshold that a region must overcome the minimum threshold to grow constantly. Consequently, directions of regional growth are characterized by two growth paths depending on the initial condition of a region. That is to say, a region below the minimum threshold is converging toward the lower stable equilibrium point over time. When a regional economy initially lies above the minimum threshold, it will grow forever. A regional economy is not thus necessarily converging a stationary is not thus necessarily converging a stationary equilibrium point through factor movement. Finally, the impacts of the presence of agglomeration economies and diseconomies are analyzed through the phase diagram. The paper also shows that agglomeration economies result in lowering the minimum threshold and in escalating the level of stable equilibrium However, when agglomeration diseconomies prevail, the results are opposite, i.e., rising the minimum threshold of growth and lowering the growth level of stable equilibrium.

• Journal of the Korean Society for Nondestructive Testing
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• v.33 no.1
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• pp.69-72
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• 2013

In long-range ultrasonic testing, a phased array probe composed of multiple identical transducers with an uniform interval of one quarter wavelength is usually used for the transmission or reception directivity control. This paper shows that the propagation directions of individual echoes can be identified in real time by displaying the inputs of a process for summing the constitution reception signals after compensating the phase difference due to the transducer interval, together with the output of the process. A constructive interference of the constitution echoes indicates a forward direction echo propagating along an intended direction while a destructive interference implies a reverse direction echo propagating along the direction opposite to the intended one.

• Proceedings of the SAREK Conference
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• 2005.11a
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• pp.380-385
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• 2005

An experimental apparatus was constructed to obtain vapor-liquid equilibrium data for $CO_2$/oil mixtures using mass analysis method with sample cylinder. Lubricants employed were POE(Polyol Ester) oil and PAG(Poly Alkylene Glycol) oil. The phase equilibria of $CO_2$/oil mixtures formed in high pressure equilibrium cell are observed through sight glasses at the opposite ends. Data were measured over the temperature range from -10 to $10^{\circ}C$ with $5^{\circ}C$ intervals under pressures up to 14 MPa. Mole fractions were calculated for $CO_2$/oil and $CO_2$/PAAG, respectively and were compared with each other.

• Journal of the Korean institute of surface engineering
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• v.37 no.4
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• pp.226-233
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• 2004

The residual stresses on the surfaces of low carbon 12Cr steels used as a nuclear steam turbine blade material have been studied by controlling the flame hardening surface treatments. The temperature cycles on the surfaces of 12Cr steel were controlled precisely as a function of both the surface temperature and cooling rate. The final residual stress state generated by flame hardening was dominated by two opposite competitive contributions; one is tensile stress due to phase transformation and the other is compressive stress due to thermal contraction on cooling. The optimum processing temperatures required for the desirable residual stress and hardness were in the range of $850^{\circ}C$ to $960^{\circ}C$ on the basis of the specification of GE power engineering. It was also observed that the high residual tensile stress generated by flame hardening induced the cracks on the surfaces, especially across the prior austenite grain boundaries, and the material failure virtually, which might limit practical use of the surface engineered parts by flame hardening.

• Wind and Structures
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• v.21 no.3
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• pp.289-309
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• 2015

Vertical profiles of mean and fluctuating wind velocities over water waves were studied, by performing Large-Eddy Simulations (LES) on a fully developed turbulent boundary layer over simplified water waves. The water waves were simplified to two-dimensional, periodic and non-evolving. Different wave steepness defined by $a/{\lambda}$ (a : wave amplitude; ${\lambda}$ : wavelength) and wave age defined by $c/U_b$ (c: phase velocity of the wave; $U_b$ : bulk velocity of the air) were considered, in order to elaborate the characteristics of mean and fluctuating wind profiles. Results shows that, compared to a static wave, a moving wave plays a lesser aerodynamic role as roughness as it moves downstream slower or a little faster than air, and plays more aerodynamic roles when it moves downstream much faster than air or moves in the opposite direction to air. The changes of gradient height, power law index, roughness length and friction velocity with wave age and wave amplitude are presented, which shed light on the wind characteristics over real sea surfaces for wind engineering applications.