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Efficacy and Safety of Dexmedetomidine for Postoperative Delirium in Adult Cardiac Surgery on Cardiopulmonary Bypass

  • Park, Jae Bum;Bang, Seung Ho;Chee, Hyun Keun;Kim, Jun Seok;Lee, Song Am;Shin, Je Kyoun
    • Journal of Chest Surgery
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    • v.47 no.3
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    • pp.249-254
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    • 2014
  • Background: Delirium after cardiac surgery is associated with serious long-term negative outcomes and high costs. The aim of this study is to evaluate neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine, compared with the current postoperative sedative protocol (remifentanil) in patients undergoing open heart surgery with cardiopulmonary bypass (CPB). Methods: One hundred and forty two eligible patients who underwent cardiac surgery on CPB between April 2012 and March 2013 were randomly divided into two groups. Patients received either dexmedetomidine (range, 0.2 to $0.8\;{\mu}g/kg/hr$; n=67) or remifentanil (range, 1,000 to $2,500\;{\mu}g/hr$, n=75). The primary end point was the prevalence of delirium estimated daily via the confusion assessment method for intensive care. Results: When the delirium incidence was compared with the dexmedetomidine group (6 of 67 patients, 8.96%) and the remifentanil group (17 of 75 patients, 22.67%) it was found to be significantly less in the dexmedetomidine group (p<0.05). There were no statistically significant differences between two groups in the extubation time, ICU stay, total hospital stay, and other postoperative complications including hemodynamic side effects. Conclusion: This preliminary study suggests that dexmedetomidine as a postoperative sedative agent is associated with significantly lower rates of delirium after cardiac surgery.

Active Materials for Energy Conversion and Storage Applications of ALD

  • Sin, Hyeon-Jeong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.75.2-75.2
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    • 2013
  • Atomic layer deposition (ALD), utilizing self-limiting surface reactions, could offer promising perspectives for future efficient energy conversion devices. The capabilities of ALD for surface/interface modification and construction of novel architectures with sub-nanometer precision and exceptional conformality over high aspect ratio make it more valuable than any other deposition methods in nanoscale science and technology. In the context, a variety of researches on fabrication of active materials for energy conversion applications by ALD are emerging. Among those materials, one-dimensional nanotubular titanium dioxide, providing not only high specific surface area but also efficient carrier transport pathway, is a class of the most intensively explored materials for energy conversion systems, such as photovoltaic cells and photo/electrochemical devices. The monodisperse, stoichiometric, anatase, TiO2 nanotubes with smooth surface morphology and controlled wall thickness were fabricated via low-temperature template-directed ALD followed by subsequent annealing. The ALD-grown, anatase, TiO2 nanotubes in alumina template show unusual crystal growth behavior which allows to form remarkably large grains along axial direction over certain wall thickness. We also fabricated dye-sensitized solar cells (DSCs) introducing our anatase TiO2 nanotubes as photoanodes, and studied the effect of blocking layer, TiO2 thin films formed by ALD, on overall device efficiency. The photon convertsion efficiency ~7% were measured for our TiO2 nanotubebased DSCs with blocking layers, which is ~1% higher than ones without blocking layer. We also performed open circuit voltage decay measurement to estimate recombination rate in our cells, which is 3 times longer than conventional nanoparticulate photoanodes. The high efficiency of our ALD-grown, anatase, TiO2 nanotube-based DSCs may be attributed to both enhanced charge transport property of our TiO2 nanotubes photoanode and the suppression of recombination at the interface between transparent conducting electrode and iodine electrolytes by blocking layer.

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A Study on Satisfaction with Makeup-kits and Makeup-kit Brand Development -Focused on Lifelong Education Centers of Colleges-

  • Kim, EunSil;Chung, Ju-Im
    • Journal of Fashion Business
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    • v.19 no.3
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    • pp.31-42
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    • 2015
  • The purpose of this study is to develop a new makeup-kit brand for education, analyzing customer satisfaction of makeup-kits used in makeup lessons provided by lifelong education centers of colleges. The research method is as follows. In order to understand the current status of the kits used in makeup lessons offered by lifelong education centers of colleges in South Korea, the study conducted a survey from October 10 of 2014 to October 31 via fax, telephone and e-mail targeting these 98 colleges that were open makeup-courses available in October 2014. As for an analysis technique, the study used a frequency analysis. In order to develop a makeup-kit brand, the study investigated these makeup-kits as well and presented a BI draft and a makeup-kit design that the study had created for itself using Photoshop CS6 and Illustrator CS4. According to findings of the survey, the students were not satisfied with kits that had too many items, were high in price and had poor case design. In the light of that, the study conducted to develop a low to middle priced makeup-kit ranging from 110,000 KRW and 150,000 KRW with approximately 26 items. In terms of a case design, black was a dominant color which would make the case feel simple and modern. Dimensions of a small size makeup-kit container were 22cm*35cm*37cm with a sponge and rubber pad proposed as product ideas. The study also worked on a BI design.

Influence of vacancy defects on vibration analysis of graphene sheets applying isogeometric method: Molecular and continuum approaches

  • Tahouneh, Vahid;Naei, Mohammad Hasan;Mashhadi, Mahmoud Mosavi
    • Steel and Composite Structures
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    • v.34 no.2
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    • pp.261-277
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    • 2020
  • The main objective of this research paper is to consider vibration analysis of vacancy defected graphene sheet as a nonisotropic structure via molecular dynamic and continuum approaches. The influence of structural defects on the vibration of graphene sheets is considered by applying the mechanical properties of defected graphene sheets. Molecular dynamic simulations have been performed to estimate the mechanical properties of graphene as a nonisotropic structure with single- and double- vacancy defects using open source well-known software i.e., large-scale atomic/molecular massively parallel simulator (LAMMPS). The interactions between the carbon atoms are modelled using Adaptive Intermolecular Reactive Empirical Bond Order (AIREBO) potential. An isogeometric analysis (IGA) based upon non-uniform rational B-spline (NURBS) is employed for approximation of single-layered graphene sheets deflection field and the governing equations are derived using nonlocal elasticity theory. The dependence of small-scale effects, chirality and different defect types on vibrational characteristic of graphene sheets is investigated in this comprehensive research work. In addition, numerical results are validated and compared with those achieved using other analysis, where an excellent agreement is found. The interesting results indicate that increasing the number of missing atoms can lead to decrease the natural frequencies of graphene sheets. It is seen that the degree of the detrimental effects differ with defect type. The Young's and shear modulus of the graphene with SV defects are much smaller than graphene with DV defects. It is also observed that Single Vacancy (SV) clusters cause more reduction in the natural frequencies of SLGS than Double Vacancy (DV) clusters. The effectiveness and the accuracy of the present IGA approach have been demonstrated and it is shown that the IGA is efficient, robust and accurate in terms of nanoplate problems.

Syntheses of Alternating Head-to Head Vinyl Copolymers and Vinyl Terpolymers via Ring-Opening Mechanism. Ring-Opening Polymerization of Substituted-3,4-dihydro-2H-pyrans

  • Lee, Ju-Yeon;Cho, I-Whan
    • Bulletin of the Korean Chemical Society
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    • v.8 no.2
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    • pp.96-101
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    • 1987
  • 2-Ethoxy-6-methoxy-5-cyano-3,4-dihydro-2H-pyran (1_a$), 2-n-butoxy-6-methoxy-5-cyano-3,4-dihydro-2H-pyr an (1b), 2-isobutoxy-6-methoxy-5-cyano-3,4-dihydro-2H-py ran ($1_c$), and 2-ethoxy-6-methoxy-3-methyl-5-cyano-3,4-dihydro -2H-pyran ($1_d$) were prepared by (4 + 2) cycloaddition reaction of methyl $\alpha$-cyanoacrylate with the corresponding alkyl vinyl ethers. Compounds $1_{a-d}$ were ring-open polymerized by cationic catalyst to obtain alternating head-to-head (H-H) copolymers. For comparison, head-to-tail (H-T) copolymer $3_a$ was also prepared by free radical copolymerization of the corresponding monomers. The H-H copolymer exhibited minor differences in its $1_H% NMR and IR spectra, but in the $^{13}C$ NMR spectra significant differences were observed between the H-H and H-T copolymers. Glass transition temperature ($T_g$) of H-H copolymer was higher than that of the H-T copolymer, but thermal decomposition temperature of the H-H copolymer was lower than that of the H-T copolymer. Compounds $1_a$, $a_b$, and $1_c$, copolymerized well with styrene by cationic catalyst, but compound 1d failed to copolymerize with styrene. All of the H-H and H-T copolymers were soluble in common solvents and the inherent viscosities were in the range 0.2-0.4 dl/g.

A study on experience of childcare service providers for adolescent parents (청소년부모 양육지원가의 양육지원서비스 제공 경험)

  • Kim, Ji-Hye
    • Journal of Digital Convergence
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    • v.19 no.10
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    • pp.435-451
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    • 2021
  • The purpose of the study is to explore the experience of participants who have provided a chidlcare service, and to suggest implications for childcare service for adolescent parents. The author used a purposive sampling method to select 3 cases with experiences related to childcare service, collecting data via direct interview and by obtaining a written text describing their case management. An inductive (open) coding approach was utilized to draw themes and categories from the data. The 6 categories describing service providing experiences of the study participants include "motives for participate a childcare service", "contents of service provided by participants", "tries to establish relationship with adolescent parents", "deepening of understand about adolescent parents", "limits of providing services". Implications and future directions were discussed for childcare services on adolescent parents having crisis related to childbirth and child rearing.

A Delphi Study on Competencies of Future Green Architectural Engineer (근미래 친환경 건축분야 엔지니어에게 필요한 역량에 대한 델파이 연구)

  • Kang, So Yeon;Kim, Taeyeon;Lee, Jungwoo
    • Journal of Engineering Education Research
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    • v.21 no.3
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    • pp.56-65
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    • 2018
  • With rapid advance of technologies including information and communication technologies, jobs are evolving faster than ever. Architectural engineering is no exception in this regard, and the green architectural engineering is emerging fast as a promising new field. In this study, a Delphi study of expert architectural engineers are conducted to find out (1) near future prospects of the field, (2) near future emerging jobs, (3) competencies needed for these jobs, and (4) educational content necessary to build these competencies with regards to the green architectural engineering. Initial Delphi survey consisting of open-ended questions in the above four areas were conducted and came out with 65 items after duplicate removal and semantic refinements. Further refinements via second and third wave of Delphi results into 40 items that the 13 architectural engineering experts may largely agree upon as future prospects with regards to the green architectural engineering. Findings indicate that it is expected that the demand for green architectural engineering and needs for automatic energy control system increase. Also, collaborations with other fields is becoming more and more important in green architectural engineering. The professional work management skills such as knowledge convergence, problem solving, collaboration skills, and creativity linking components from various related areas seem to also be on the increasing need. Near future ready critical skills are found to be the building environment control techniques (thermal, light, sound, and air), the data processing techniques like data mining, energy monitoring, and the control and utilization of environmental analysis software. Experts also agree on new curriculum for green building architecture to be developed with more of converging subjects across disciplines for future ready professional skills and experiences. Major topics to be covered in the near future includes building environment studies, building energy management, energy reduction systems, indoor air quality, global environment and natural phenomena, and machinery and electrical facility. Architectural engineering community should be concerned with building up the competencies identified in this Delphi preparing for fast advancing future.

Digital Diplomacy via Social Networks: A Cross-National Analysis of Governmental Usage of Facebook and Twitter for Digital Engagement

  • Ittefaq, Muhammad
    • Journal of Contemporary Eastern Asia
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    • v.18 no.1
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    • pp.49-69
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    • 2019
  • Over the last couple of years, digital diplomacy has become a fascinating area of research among Mass Communication, Peace and Conflict Studies, and International Affairs scholars. Social media and new technology open up new avenues for governments, individuals, and organizations to engage with foreign audiences. However, developing countries' governments are still lacking in the realization of the potential of social media. This study aims to analyze the usage of social media (Facebook & Twitter) by the two biggest countries in South Asia (Pakistan and India). I selected 10 government officials' social media accounts including prime ministers', national press offices', military public relations offices', public diplomacy divisions', and ministries of foreign offices' profiles. The study relies on quantitative content analysis and a comparative research approach. The total number of analyzed Twitter tweets (n=1,015) and Facebook posts (n=1,005) include 10 accounts, five from each country. In light of Kent and Taylor's (1998) dialogic communication framework, the results indicate that no digital engagement and dialogue occurs between government departments and the public through social networking sites. Government departments do not engage with local or foreign audiences through digital media. When comparing both countries, results reveal that India has more institutionalized and organized digital diplomacy. In terms of departmental use of social media, the digital diplomacy division and foreign office of India is more active than other government departments in that nation. Meanwhile, Pakistan's military public relations office and press office is more active than its other government departments. In conclusion, both countries realize the potential of social media in digital diplomacy, but still lack engagement with foreign audiences.

Investigation of wave propagation in anisotropic plates via quasi 3D HSDT

  • Bouanati, Soumia;Benrahou, Kouider Halim;Atmane, Hassen Ait;Yahia, Sihame Ait;Bernard, Fabrice;Tounsi, Abdelouahed;Bedia, E.A. Adda
    • Geomechanics and Engineering
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    • v.18 no.1
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    • pp.85-96
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    • 2019
  • A free vibration analysis and wave propagation of triclinic and orthotropic plate has been presented in this work using an efficient quasi 3D shear deformation theory. The novelty of this paper is to introducing this theory to minimize the number of unknowns which is three; instead four in other researches, to studying bulk waves in anisotropic plates, other than it can model plates with great thickness ratio, also. Another advantage of this theory is to permits us to show the effect of both bending and shear components and this is carried out by dividing the transverse displacement into the bending and shear parts. Hamilton's equations are a very potent formulation of the equations of analytic mechanics; it is used for the development of wave propagation equations in the anisotropic plates. The analytical dispersion relationship of this type of plate is obtained by solving an eigenvalue problem. The accuracy of the present model is verified by confronting our results with those available in open literature for anisotropic plates. Moreover Numerical examples are given to show the effects of wave number and thickness on free vibration and wave propagation in anisotropic plates.

Effects of Consecutive whole Body Vibration Exercise using Heel Raise Posture on Neuromuscular Response during Single-leg Stance (뒤꿈치 들기 자세를 이용한 전신진동 운동이 외발서기 시 근신경 반응에 미치는 영향)

  • Kim, Dae Dong;Lee, Myeounggon;Youm, Changhong
    • Korean Journal of Applied Biomechanics
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    • v.31 no.2
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    • pp.104-112
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    • 2021
  • Objective: This study aimed to analyze the effects of consecutive whole body vibration through heel raise posture on the center of pressure and electromyography of anterior tibial muscle, lateral gastrocnemius and soleus muscles during single-leg stance. Method: The subjects of this study included 30 healthy males in their 20's, with the following inclusion criteria: no history of orthopaedic medical history, no participation in regular exercises, no history of whole body vibration exercise, and right leg being the dominant leg. The experimental procedure involved pretreatment measurement of eye open single-leg stance, application of whole body vibration for 30 seconds, post-treatment measurement (3 measurements in total). Static and dynamic movements have been measured over 2 separate experiments, with 72 hours gap between the experiments. Static movement involved maintaining single-leg heel raise posture for 30 seconds while applying whole body vibration, and dynamic movement involved heel raise (15 repetitions over 30 seconds) while applying whole body vibration. The strength of applied whole body vibration was 35 Hz frequency and 2~4 mm amplitude. Results: As the single-leg posture after static heel raise posture, mediolateral velocity of the center of pressure at post 2 and post 3 were significantly reduced compared to the pre-treatment measurement. In addition, the percentage for reference voluntary contraction in anterior tibial muscle and soleus and median frequency at anterior tibial muscle and lateral gastrocnemius muscle at post 3 were significantly decreased compared to the pre-treatment value. As the single-leg posture after dynamic heel raise posture, the mediolateral 95% edge frequency of the center of pressure and median frequency at anterior tibial muscle, lateral gastrocnemius muscle, and soleus muscle at post 3 were significantly reduced compared to the pre-treatment value. Conclusion: Acute whole body vibration via static and dynamic heel raise posture have positive effect on mediolateral posture control during single-leg stance.