Background: The effects of omega-3 polyunsaturated fatty acids (PUFAs) on cerebral vessels have not been clarified until now. Thus we investigated the efficacy of omega-3 PUFAs supplementation on cerebral blood flow velocity and vascular resistance via transcranial doppler (TCD). Methods: Consecutive twenty patients (13 male and 7 female) with at least 1 cerebrovascular risk factor or a known cerebrovascular disease were enrolled. Patients were treated with omega-3 PUFAs (1 g, two times per day) for 12 weeks. Cerebral blood flow velocity, resistance index, and pulsatile index were checked before and after 12 weeks of treatment using TCD. Results: The change of resistance index in right MCA (from $0.58{\pm}0.07$ to $0.55{\pm}0.07$, p = 0.042) and left PCA (from $0.56{\pm}0.07$ to $0.53{\pm}0.06$, p = 0.037) showed significant improvement after 12 weeks of omega-3 PUFAs treatment. The changes in other vessels, however, failed to show any significant changes compared to the baseline. Conclusions: Omega-3 PUFAs treatment showed feasible efficacies for cerebral vascular resistances in this open label trial. To confirm these results, larger samples of patients and longer period of follow-up is warranted.
With rapid advances on Interactive technology, and the growing popularity of the Internet, Internet shopping receives considerable attention in both the popular-press and academic journals. The Internet has enormous commercial possibilities. But it is a new and dynamic medium that poses special challenges for marketers. The revolutionary nature of the Internet mandates that established wisdom on consumer marketing along with marketing-mix strategies has to be reexamined and perhaps radically revised. In order to assist marketers in this endeavor it is critical to understand consumers' buying behaviors of Internet shopping. But research in this area still very much its infancy. This study examined previous researches of Internet shopping and developed conceptual framework of Internet shopping modes. Additionally, this study examined empirical investigation of Internet shopping. Preliminary results suggests that there are significant differences in individuals' perceptions of Internet shopping and traditional shopping modes. Various factors influences on consumers' buying behavior on Internet shopping. There are Individuals' factors(personality, lifestyle, prior experience, perceived risk etc), shopping mall factors(trust, vividness, security, promotion, etc), product characteristics(product category, brand, etc), situational factors(time pressure, locational constraints etc), social/cultural factors(Norms, importance of other peoples etc). Additionally, We conducted empirical study of the impact of the Internet on consumer shopping behavior. We gathered consumers' reactions via an open-ended survey using a sample of 90 shoppers. We related the reactions to the factors of consumers' satisfaction or dissatisfaction of the Internet shopping. Consequently, there are many questions regarding factors that might influence Internet shopping. From theoretical and practical perspectives, studies that examine these factors would seem to offer much to the discipline. This paper has attempted th provide insights and direction of future empirical examination of Internet shopping.
Aly, Aly Mousaad;Chowdhury, Arindam Gan;Bitsuamlak, Girma
Wind and Structures
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v.14
no.4
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pp.285-300
/
2011
Researchers at the International Hurricane Research Center (IHRC), Florida International University (FIU), are working in stages on the construction of a large state-of-the-art Wall of Wind (WoW) facility to support research in the area of Wind Engineering. In this paper, the challenges of simulating hurricane winds for the WoW are presented and investigated based on a scale model study. Three wind profiles were simulated using airfoils, and/or adjustable planks mechanism with and without grids. Evaluations of flow characteristics were performed in order to enhance the WoW's flow simulation capabilities. Characteristics of the simulated wind fields are compared to the results obtained from a study using computational fluid dynamics (CFD) and also validated via pressure measurements on small-scale models of the Silsoe cube building. Optimal scale of the test model and its optimal distance from the WoW contraction exit are determined - which are two important aspects for testing using an open jet facility such as the WoW. The main objective of this study is to further the understanding of the WoW capabilities and the characteristics of its test section by means of intensive tests and validations at small scale in order to apply this knowledge to the design of the full-scale WoW and for future wind engineering testing.
The attractant (orange light) or repellent (white light) signal is transmitted from SRI (Sensory Rhodopsin I) via protein-protein interaction with its transducer Htrl (Halobacterial Transducer for Sensory Rhodopsin I) which in turn controls a cytoplasmic phospho-transfer pathway that modulates flagella motor switching in Halobacterium salinarum. Some mutations in both SRI and Htrl showed an unusual mutant phenotype called inverted signaling, in which the cell produces a repellent response to normally attractant light. Twelve mutations at the Glutamate 56 (E56) position in the second transmembrane helix of Htrl were introduced by site-specific random mutagenesis. Almost all E56 mutants showed orange-light inverted responses in pH and temperature-dependent manners except E56D and E56Y. Except for these two mutants, all mutants accelerated the $S_{373}$ decay compared to wild-type at $18^{\circ}C$. This supported that there is an interaction between SRI and the second transmembrane of Htrl. Also a structural model of Htrl based on the Tar crystal structure and the secondary structure prediction program proposed the E56 residue to be in the middle of the proton channel. The most important observation is that the E56 mutant provides the evidence that this residue is very sensitive for signal relay, which can be explained by the open and closed conformations of the channel (A and R conformations) in SRI, as was postulated by the unified conformational shuttling model for transport and signaling.
In response to the South Korean government's trade diversification policy, the New Southern Policy, research is needed into the large population of Muslim fashion consumers who live there. Currently, veils worn by Muslim women are becoming a part of fashion collections as a style choice not just as a religious requirement. As such, the aim of this study is to investigate the fashion characteristics of the Southeast Asian Hijabistas. To do this we investigate the activities and the meanings of recent changes in the Southeast Asian fashion market, we also take a look at the Hijabistas who lead these changes. This is carried out as a theoretical study via literature review. In addition to this research, we selected 6 Hijabistas from Indonesia and Malaysia and analyzed 204 of their SNS photos. The results showed that the sportive image was popular; in terms of veils, hijabs and turbans were most popular; while pants and T-shirts dominated the clothing choices. Black and neutral colors were most popular but a variety of colors and tones were represented. In terms of fabric patterns, most of the choices were solid with no patterns. In terms of the types of veil used, in order of most to least popular were: hijabs covering down to the neck, turbans, and hijabs covering down to the chest. It was found that the Hijabista in Indonesia and Malaysia prefer an open, trendy fashion style. In conclusion, it was found that the Southeast Asia Muslim Fashion community are utilizing hijabs to express their identity not only as a Muslim and but also as a fashion item.
The putative EPA synthesis gene cluster was mined from the entire genome sequence of Shewanella oneidensis MR-1. The gene cluster encodes a PKS-like pathway that consists of six open reading frames (ORFs): ORFSO1602 (multi-domain beta-ketoacyl synthase, KS-MAT-4ACPs-KR), ORFSO1600 (acyl transferase, AT), ORFSO1599 (multi-domain beta-ketoacyl synthase, KS-CLF-DH-DH), ORFSO1597 (enoyl reductase, ER), ORFSO1604 (phosphopentetheine transferase, PPT), and ORFSO1603 (transcriptional regulator). In order to prove involvement of the PKS-like machinery in EPA synthesis, a 20.195-kb DNA fragment containing the genes was amplified from S. oneidensis MR-1 by the long-PCR method. Its identity was confirmed by the methods of restriction enzyme site mapping and nested PCR of internal genes orfSO1597 and orfSO1604. The DNA fragment was cloned into Escherichia coli using cosmid vector SuperCos1 to form pCosEPA. Synthesis of EPA was observed in four E. coli clones harboring pCosEPA, of which the maximum yield was 0.689% of the total fatty acids in a clone designated 9704-23. The production yield of EPA in the E. coli clone was affected by cultivation temperature, showing maximum yield at $20^{\circ}C$ and no production at $30^{\circ}C$ or higher. In addition, production yield was inversely proportional to glucose concentration of the cultivation medium. From the above results, it was concluded that the PKS-like modules catalyze the synthesis of EPA. The synthetic process appears to be subject to regulatory mechanisms triggered by various environmental factors. This most likely occurs via the control of gene expression, protein stability, or enzyme activity.
Journal of the Korean Institute of Landscape Architecture
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v.29
no.4
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pp.1-11
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2001
The purpose of this study is to re-interpretate the meaning of place from the perspective view of events. In the realm of events, time, process, and evolution are emerging as more important elements for better places rather than space or fixed physical elements. First, this study reviews the phenomenological contribution to the meaning of place by discussing differences between positivism and phenomenology. The phenomenological approach has strengths that can perceive individual experiences and idiosyncraises through a holistic approach and qualitative methods. However, it has weaknesses such as unpredictability, subjectivity and ambiguity. In order to overcome these weaknesses, the notion of singularities(pure events) on the metaphysical plane existing between nature and culture is explored via Deleuzean concepts(Post-structuralism); singularities become events(simulacre) through ´becoming´ and these events have meaning through this process in the particular place. By this process, the subject an feed a sense of place through this meaning. Events unexpectedly create a series of events and have impact in the future. Creating various events in the particular place requires many contextural settings where the embodied perceptions could take place. Describing the potentiality of embodied perceptions demands ´smooth space´ rather than ´striated space´. Smooth space refers to the space where orientations and linkages are in continuous variation. Recent architectural and landscape architectural design projects reveal that the emphasis is placed on the open-ended set of various events unfolding over time rather than the physical settings of the place. For better landscape design, new concepts need to be introduced and implemented. These new concepts should focus on creating a series of events and considering the evolution of the place over time through multi-contextural and rhizomatical synthesis rather than rigid and static master plan of SAD(survey-analysis-design) methodology.
Kronewitter, F. Dell;Ryu, Bo;Zhang, Zhensheng;Ma, Liangping
Journal of Communications and Networks
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v.13
no.5
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pp.518-524
/
2011
A high assurance IP encryption (HAIPE) compliant protocol accelerator is proposed for military networks consisting of red (or classified) networks and black (or unclassified) networks. The boundary between red and black sides is assumed to be protected via a HAIPE device. However, the IP layer encryption introduces challenges for bandwidth on demand satellite communication. The problems experienced by transmission control protocol (TCP) over satellites are well understood: While standard modems (on the black side) employ TCP performance enhancing proxy (PEP) which has been shown to work well, the HAIPE encryption of TCP headers renders the onboard modem's PEP ineffective. This is attributed to the fact that under the bandwidth-on-demand environment, PEP must use traditional TCP mechanisms such as slow start to probe for the available bandwidth of the link (which eliminates the usefulness of the PEP). Most implementations recommend disabling the PEP when a HAIPE device is used. In this paper, we propose a novel solution, namely broadband HAIPE-embeddable satellite communications terminal (BHeST), which utilizes dynamic network performance enhancement algorithms for high latency bandwidth-on-demand satellite links protected by HAIPE. By moving the PEP into the red network and exploiting the explicit congestion notification bypass mechanism allowed by the latest HAIPE standard, we have been able to regain PEP's desired network enhancement that was lost due to HAIPE encryption (even though the idea of deploying PEP at the modem side is not new). Our BHeST solution employs direct video broadcast-return channel service (DVB-RCS), an open standard as a means of providing bandwidth-on-demand satellite links. Another issue we address is the estimation of current satellite bandwidth allocated to a remote terminal which is not available in DVBRCS. Simulation results show that the improvement of our solution over FIX PEP is significant and could reach up to 100%. The improvement over the original TCP is even more (up to 500% for certain configurations).
Journal of the Korean Society for Aeronautical & Space Sciences
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v.33
no.3
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pp.47-56
/
2005
This paper presents a performance improvement result with the aid of closed feedback controller loop to a micro gyroscope. The dynamic model of a micro gyroscope is derived and a conventional proportional and derivative controller is designed via frequency domain analysis. The proposed control loop is implemented using several analog devices and applied to the SNU-Bosch MEMS gyroscope to check its performance improvement in real environment. The experiments demonstrated the performance improvement with the proposed feedback control loop. The bandwidth, linearity, and bias stability are improved to 78 Hz, 0.504 %, and 0.043 deg/sec, respectively, from 35 Hz, 2.07 %, and 0.066 deg/sec of open loop system.
The purpose of this study was to compare and evaluate the bleaching efficacy of three nonvital bleaching techniques: Walking bleaching, Walking bleaching and heat application, and Walking bleaching and bleaching light application. 36 extracted anterior teeth with intact crowns were immersed in 5 % sodium hypochlorite solution for twenty-four hours to loosen extrinsic debris. Lingual access openings were prepared in all teeth and the pulps were extirpated. The teeth were stored in 5% sodium hypochlorite for twenty-four hours to open the dentinal tubules and they were stained via whole blood. Once the teeth were stained, they were evaluated with Colorimeter. The teeth in each group were ranked from lightest to darkest and divided equally into three experimental groups in which the following bleaching techniques were used. Intracoronal base was placed 2mm below cementoenamel junction. Group 1 Walking bleaching (Superoxol + Sodium perborate) Group 2 Heat application + Walking bleaching (Superoxol+Sodium perborate) Group 3 Light application+Walking bleaching (Superoxol+Sodium perborate) The bleaching agents were changed every 3 days and the teeth were bleached for a total of 14 days. The teeth were evaluated with Colorimeter before the start of any bleaching and on day 14. The results were as follows: 1. At the end of 14 days, all the sample teeth demonstrated the increase of Lightness Index at cervical 1/3 of crown (p<0.05) Lightness Index was significant difference in group 2 and 3, but there were some minor differences among groups (p>0.05). 2. In all groups, there was significant difference in red chromacity (p<0.05), but there were some minor differences among groups (p>0.05). 3. In all groups, there was no significant difference in yellow chromacity (p>0.05).
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