• The Journal of the Korea institute of electronic communication sciences
• /
• v.13 no.3
• /
• pp.601-608
• /
• 2018

While the legislation on the protection of personal information in public institutions was enacted and amended, the guidelines and laws on information security were focused, contracted and realized with focus on specific institutions. Mutual laws and guidelines have been applied and realized for the dual purpose of securing both the asset of macroscopic information and the asset of personally identification information, which are mutually different media information. However, in a bid to present the definition and direction of the fourth industrial revolution in 2017, a variety of products and solutions for security designed to ensure the best safety line of the 21st century, and the third technology with the comprehensive coverage for all these fields, a number of solutions and technologies, including IOT(: Internet of Things), ICT Internet of Things(: ICT), ICT Cloud, and AI (: Artificial Intelligence) are pouring into the security market as if plastic doll toys were manufactured in massive scale into the market. With the rising need for guaranteeing the interrelation for securities with dualistic physical, administrative, logical and psychological differences, that is, information security and personal information security that are classified into two main categories and for the enhanced security for integrated management and technical application, the study aims to acquire the optimal security by analyzing the interrelationship between the two cases and applying it to the study results.

• Herbal Formula Science
• /
• v.14 no.2
• /
• pp.76-85
• /
• 2006

Objectives : We Investigated the effect of Dioscoreae Rhizoma(山藥) on the change of the corticosterone and the rectal temperature(直腸溫渡) of the mice induced by starvation stress(創戰 스트레스). Methods : After administration of Dioscoreae Rhizoma (0.25g/kg, 0.5g, 1.0g/kg, 3g/kg) three times, mice were starved. The corticosterone and rectal temperature were measured after 36.5 hours starvation stress. Results : The plasma cortiosterone levels in the S-2, S-3 and S-4 group were decreased significantly comparing with the control group (P<0.01) after 36.5 hours starvation stress. and rectal temperature was decreased in the control goup comparing with the normal group, but there is no significant change in the Dioscoreae Rhizoma treated group. Conclusion : it might be recognized that Dioscoreae Rhizoma has preventive-effect against starvation stress and also it might be needed further study in various viewpoints. Objectives : This study was disegned to elucidate the short term effect of Rossa rugosae Radix on proliferation. differentiation and maturation of 3T3-L1 Preadipocyte. Methods: 3T3-L1 preadipocytes obtained from Korean Cell Line Bank were cultured in a D ulbecco’ s modified eagle medium(MEM) culture solution containing 10% fetal bovine serum(FBS) and various concentrations of aqueous extract of Rossa rugosae Radix.. The short term effect of the extract of Rossa rugosae Radix on proliferation. differentiation and maturation of 3T3-L1 preadipocytes were investigate after treatment for 24 hours by measuring MTT. Oil Red 0 and latate dehydrogenase activity.. Results: The Rossa rugosae Radix extract inhibited significantly the proliferation of 3T3-L1 preadipocytes and tended to increase latate dehydrogenase activity in the media of differentiated 3T3-L1 preadipocytes & matured 3T3-L1 preadipocytes. the extract also inhibit the lipid accumulation of differentiated 3T3-L1 preadipocytes & matuered 3T3-L1 preadipocytes. Conclusions: These results demonstrated that the Rossa rugosae Radjx extract inhibited the proliferation. differentiation and maturation of 3T3-L1 preadipocytes. suggesting that Rossa rugosae Radix has anti-obesity effect: however further in vivo study is needed to demonstrate its pharmacological effects.

• Journal of the Korean Society for information Management
• /
• v.39 no.3
• /
• pp.263-292
• /
• 2022

The purpose of this study is to identify the topics of research related to the concepts of literacy in the field of Library and Information Science which is related to user education in libraries. Data were collected from the WoS and KCI databases, and complementary keyword analysis and topic modeling analysis techniques were used to identify topics of literature-related research articles in the field of Library and Information Science. Findings presented that there was a difference in keywords and topics between the two databases. Literacy-related topics identified from the KCI database were classified into three groups through topic modeling. Also, it was analyzed that there is a difference between the overall literacy-related research trend, the timing of the surge in research volume, and key frequent keywords in the Library and Information Science field confirmed in the study. In particular, in the study of literacy in all fields, a number of words such as 'literacy', 'education', 'media', and 'digital' were derived. However, in literature research in the field of Library and Information Science, keywords such as 'information utilization ability' and 'school library' appeared. Based on this, it was concluded that research on the ability to develop an evaluative eye for information is needed in line with today's information environment, where information is rapidly increasing in Korea in the future.

• Korean Journal of Radiology
• /
• v.21 no.9
• /
• pp.1077-1086
• /
• 2020

Objective: To evaluate the effect of perfluorobutane microbubbles (Sonazoid^®, GE Healthcare) on steam popping during radiofrequency (RF) ablation for treating hepatocellular carcinoma (HCC), and to assess whether popping affects treatment outcomes. Materials and Methods: The institutional review board approved this retrospective study, which included 90 consecutive patients with single HCC, who received percutaneous RF ablation as the first-line treatment. The patients were divided into two groups, based on the presence or absence of the popping phenomenon, which was defined as an audible sound with a simultaneous sudden explosion within the ablation zone as detected via ultrasonography during the procedure. The factors contributing to the popping phenomenon were identified using multivariable logistic regression analysis. Local tumor progression (LTP) and disease-free survival (DFS) were assessed using the Kaplan-Meier method with the log-rank test for performing comparisons between the two groups. Results: The overall incidence of the popping phenomenon was 25.8% (24/93). Sonazoid^® was used in 1 patient (4.2%) in the popping group (n = 24), while it was used in 15 patients (21.7%) in the non-popping group (n = 69). Multivariable analysis revealed that the use of Sonazoid^® was the only significant factor for absence of the popping phenomenon (odds ratio = 0.10, p = 0.048). There were no significant differences in cumulative LTP and DFS between the two groups (p = 0.479 and p = 0.424, respectively). Conclusion: The use of Sonazoid^® has a suppressive effect on the popping phenomenon during RF ablation in patients with HCC. However, the presence of the popping phenomenon may not affect clinical outcomes.

• Radiation Oncology Journal
• /
• v.21 no.3
• /
• pp.216-221
• /
• 2003

Purpose: To investigate the modulation of radiosensitivity by celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on cancer cells over- and under-expressing COX-2. Materials and Methods: A clonogenic radiation survival analysis was performed on A549 human lung and MCF-7 human breast cancer cell lines incubated in both 1 and $10\%$ fetal bovine serum (FBS) containing media. The apoptosis in both cell lines was measured after treatment with radiation and/or celecoxib. Results: Celecoxib enhanced the radiation sensitivity of the A549 cells in the medium containing the $10\%$ FBS, with radiation enhancement ratios of 1.58 and 1.81 respectively, at surviving fractions of 0.1, with $30\muM\;and\;50\muM$ celecoxib. This enhanced radiosensitivity disappeared in the medium containing the $1\%$ FBS. Celecoxib did not change the radiation sensitivity of the MCF-7 cells in either media. The induction of apoptosis by celecoxib and radiation was not synergistic in either cell line. Conclwsion: Celecoxib, a selective COX-2 inhibitor, preferentially enhanced the effect of radiation on COX-2 over-expressing cancer cells compared to the cells with a low expression, and this effect disappeared on incubation of the cells during drug treatment in the medium with suboptimal serum concentration. Apoptosis did not appear to be the underlying mechanism of this radiation enhancement effect due to celecoxib on the A549 cells. These findings suggest radiosensitization by a selective COX-2 inhibitor is COX-2 dependent.

• Journal of Embryo Transfer
• /
• v.31 no.3
• /
• pp.191-197
• /
• 2016

Historically, Korea old cattle had been consisted with various lines of coat color brindle, black and white-brown breeds or more. The two rare lines of black and white coat color are maintained for animal resources and preserved critically. The present study was carried out to evaluate potential usage of cysteamine supplementation during in vitro matration (IVM) and in vitro culture/production of embryo (IVP) by transvaginal ultrasound-guided follicle aspiration (Ovum Pick-Up: OPU) for the establishment of cryo-banking system. Immature slaughterhouse-derived cumulus-oocyte complexes (SL-COCs) were matured in IVM medium supplemented with 0, 0.1, 0.3 or 0.9 mM cysteamine, and then cultured in mSOF-BAS for 8 days after in vitro fertilization. The treatment of 0.1 mM cysteamine on SL-COCs showed higher rate of blastocyst, so OPU-derived COCs from rare breeds were matured in TCM media supplemented with or without 0.1 mM cysteamine, FSH and 5% FBS. The embryos were evaluated their developmental stages on day 8. During IVM, cysteamine treatment significantly increased the embryo production rate of slaughterhouse-derived COCs (19.6% vs. 30.5%). The presence of cysteamine during IVM of OPU-derived COCs from rare Korean cattle breeds (albino white and black line) also increased embryo production rates than those from SL-COCs (27.4% vs. 41.9% and 36.4%). With these results, cysteamine treatment during IVM is one of key factors IVP of blastocysts to establish banking system of endangered rare Koarean cattle with OPU derived transferable blastocysts.

• Journal of Broadcast Engineering
• /
• v.21 no.1
• /
• pp.76-86
• /
• 2016

This study was investigated whether the perceived depth was changed depending on the measurement methods. In the method of direct comparison, virtual object with one of the various binocular disparities was presented in the frontal space with LEDs which were used for depth estimation for a binocular stimulus, while in the method of indirect comparison, visual object was presented in the frontal space but the LEDs were placed rightward at the angle of 45 degree from the mid-sagittal line. In these experimental setup, the depth of binocular stimulus was directly matched that of LED in direct comparison condition. In indirect comparison condition, however, observer estimated the depth of binocular stimulus, turned one's head rightward to the array of LEDs and turned on the LED which was supposed to be the same depth as binocular stimulus. Additionally, it was investigated whether the perceived depth was different depending on observer's stereo acuity. The results showed that perceived depths measured in the direct comparison were more similar to the depth predicted from geometry than those in the indirect comparison, and that the perceived depths from observers with high stereo acuity were similar to the predicted depth from geometry those from observers with low stereo acuity. These results indicated that stereoscopic depths of the binocular stimuli would vivid and compelling when binocular stimuli was simultaneously presented with real objects in the same visual space, like a mixed reality.

• Women's Health Nursing
• /
• v.2 no.1
• /
• pp.106-124
• /
• 1996

This paper reviews battering, sexual violence and divorce experienced among women. There three problems have negative influence on health status in women and are further developed to social problems such as family dissolution. The victims of the problems may manifest physical injury, emotional difficulties and social withdrawl, while their children may show problems caused by lack of parental caring and by resembling abusive behaviors of their parents. Hence, nurses need to pay attention to batting, sexual violence, and divorce and to develop relevant nursing interventions for them. Some strategies of dealing with those problems are presented in the following. First, we have to eliminate sexism prevailing in out society. Our society is assigning inequal and asymmetrical gender role. Mass media should inspire equality between genders and show a healthy model of family and community. Second, social system and laws should be changed through collective efforts. Those living conditions of women cannot be changed by the effort of women themselves only. We all need to work for establishing and changing the law, so that those women in suffering can obtain immediate and adequate protection. Third, social support system of consulting and referring women's problems should be established. Such support system as hot line, shelter and counseling clinics would help women in crisis. Fourth, job training and arrangement should be available to women who are divorced. Fifth, there should be self-help group for those women in suffering. Self-help group would help those women in sharing their problems and feelings and in establishing coping strategies. Nurses, as the largest group among health professionals, are sensitive and respond to health needs of clients and have an effect on managing women's health. However, we nurses have not been ready for dealing with problems of women, although most of us are women. we not need to change our perspective of women's health problems from a traditional medical perspective to feministic one. Accordingly, nurses need to develop realistic way of caring those women in suffering and to assist them in making decisions for their lives by themselves.

• The Journal of the Korea Contents Association
• /
• v.18 no.10
• /
• pp.631-643
• /
• 2018

This study is the first ever attempted series paper of one particular TV drama writer, Su-Hyeon Kim, with diversified and systematic scale. Along with the just before study, proving Su-Hyeon Kim's line's conceptual properties as the Bahktin's dialogism, its core of polyphony, this study is to analyze the concrete method of creation through Bahktin's Canivalistic creation component of 'Grotesque Realism' and 'Unofficial Square Language'. With her work of (SBS, 1992), this study verifies its characteristic creation of lines to be the 'Grotesque Realism' components of overturn, destruction, and creation along with 'Unofficial Square Language' components of the masses, material, physical language, and discourse of self-liberation. In this way, this study is on one hand, to overcome the application problem of Bahktin's theory as a separated one, but also to enhance the quality of the study of the writer and the lines. As a result, she has acquired her own distinction of ambivalence by the way of demotion, overturn with masses' material, physical, unofficial square language along with a stronger execution of acquiring self denial, positivity. liberation, and life. Therefore the writer is highly rated for her fierce cognition of language and her artistic spirit. Also, this paper proposes the following study to appraise the impact of the writer's differentiation and artistic spirit on the creation of Korean TV drama, contents industry, and mass media.

• Journal of Periodontal and Implant Science
• /
• v.33 no.2
• /
• pp.277-288
• /
• 2003

It has been suggested that increased number and activity of phagocytes in periodontitis lesion results in a high degree of reactive oxygen species (ROS) such as superoxide anion, hydrogen peroxide, nitric oxide and peroxynitrite. There are few reports on the relationship between ROS and MMPs expressions in gingival fibroblast. We studied to elucidate whether and how ROS, especially nitric oxide affects the MMP expression. Human gingival fibroblasts and HTl080 cells (human fibrosarcoma sell line as reference) were grown in DMEM supplemented with 10 mM HEPES, 50 mg/L gentamicin, and 10% heat inactivated fetal bovine serum with addition of various reactive oxygen species (ROS). Culture media conditioned by cells were examined by gelatin zymography. HT1080 cells expressed proMMP-2 and proMMP-9, but human gingival fibroblasts (HGF) produced only proMMP-2. Hydrogen peroxide upregulated MMP-9 expression in HT1080 cells, whereas in human gingival fibroblast SNP treatment showed marked increase in MMP-2 level compared to other ROS. These results suggest that the effects of ROS on MMPs expressions are cell-type specific. RT-PCR for MMP-2 and TIMP-2 m-RNA were performed using total RNA from cultured cells under the influence various kinase inhibitors. In HT1080 cells, treatment with FPTI III (Ras processing inhibitor) and LY294002 (PI3-kinase inhibitor) resulted in inhibition of MMP-2 and MMP-9 expressions, suggesting that Ras/P13-kinase pathway is important for MMPs expression in HT1080 cells. In gingival fibroblasts, treatment with FPTI III and PDTC (NF-kB inhibitor) showed marked decrease in MMP-2 regardless of the of SNP , suggesting that Ras/NF-kB could be the key pathway for NO-induced MMP-2 expression in gingival fibroblasts. This study showed that ROS, especially nitric oxide, could be the critical mediator of periodontal disease progression through control of MMP-2 expression in gingival fibroblasts possibly via Ras/NF-kB pathway.